Research Topics
| Rolf M F BergerSummaryAffiliation: University Medical Center Groningen Country: The Netherlands Publications
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Detail Information
Publications
Clinical features of paediatric pulmonary hypertension: a registry studyRolf M F Berger
Centre for Congenital Heart Diseases Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Netherlands
Lancet 379:537-46. 2012..The Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension (TOPP) registry is a global, prospective study designed to provide information about demographics, treatment, and outcomes in paediatric pulmonary hypertension...
Pediatric pulmonary hypertension in the Netherlands: epidemiology and characterization during the period 1991 to 2005Rosa Laura E van Loon
Department of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Circulation 124:1755-64. 2011..This study describes the nationwide epidemiological features of pediatric PH in the Netherlands during a 15-year period and the clinical course of pediatric PAH...- Left ventricular outflow tract obstruction: should cardiac screening be offered to first-degree relatives?Wilhelmina S Kerstjens-Frederikse
Department of Genetics, University Medical Centre Groningen, Groningen, The Netherlands
Heart 97:1228-32. 2011..To determine whether offering cardiac screening to relatives of patients with left ventricular outflow tract obstructions (LVOTOs) would be justified... - Pulse densitometer indocyanine green dilution curves: a simple applicable and accurate method for determination of cardiac shuntsArend Bergstra
Thorax Center Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Congenit Heart Dis 4:362-8. 2009..We therefore investigated the feasibility of a new technique, non-invasive pulse densitometry (PD) in patients with intracardiac shunts and compared its results with the established standards: cuvette densitometry (CD) and oximetry (OX)... - Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysisRolf M F Berger
University Medical Center, University of Groningen, Groningen, The Netherlands
Int J Cardiol 144:373-8. 2010..We compared the effects of bosentan and placebo in patients with isolated ASD (ASD subgroup) versus patients with isolated VSD or both defects (VSD subgroup)... 
Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertensionMirjam E van Albada
Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Eur J Pharmacol 549:107-16. 2006..However, these effects may be attributed to effects on cardiac rather than on pulmonary vascular remodeling...- Menstrual cycle and its disorders in women with congenital heart diseaseWillem Drenthen
Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Congenit Heart Dis 3:277-83. 2008..To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD)... - Biological serum markers in the management of pediatric pulmonary arterial hypertensionMirjam E van Albada
Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
Pediatr Res 63:321-7. 2008..The data indicate that these markers can be used to monitor treatment effects and predict mortality in pediatric PAH... - Drug management of fetal tachyarrhythmias: are we ready for a systematic and evidence-based approach?Freek van den Heuvel
Department of Pediatric Cardiology, Beatrix Childrens Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
Pacing Clin Electrophysiol 31:S54-7. 2008..An international registry is proposed as an important step toward obtaining the necessary data to develop evidence-based management strategies... - Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodelingMirjam E van Albada
Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
J Cardiovasc Pharmacol 48:249-54. 2006..Although regression of pulmonary vascular remodeling has been suggested as therapeutic mechanism, its mode of action remains unknown... - Down syndrome and aberrant right subclavian arteryMarcus T R Roofthooft
Department of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9700, Groningen, The Netherlands
Eur J Pediatr 167:1033-6. 2008..The presence of ARSA is not synonymous to the cause of feeding problems in patients with DS and corrective surgery of this vascular anomaly should be restricted to selected cases... - Persistent pulmonary hypertension of the newborn with transposition of the great arteriesMarcus T R Roofthooft
Department of Paediatric Cardiology, Beatrix Children s Hospital, Groningen, The Netherlands
Ann Thorac Surg 83:1446-50. 2007..However, data on its incidence and prognosis are scarce and originate mostly from the era before introduction of inhaled nitric oxide (iNO) therapy for PPHN... - Severe pregnancy-induced deterioration of truncal valve regurgitation in an adolescent patient with repaired truncus arteriosusElke S Hoendermis
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Cardiology 109:177-9. 2008..Despite severe and symptomatic deterioration of truncal valve regurgitation, she successfully delivered a healthy child, and the valve function recovered within 2 weeks postpartum... - Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesionsMirjam E van Albada
Center for Congenital Heart Disease, Beatrix Children s Hospital, Groningen, The Netherlands
Am J Physiol Lung Cell Mol Physiol 298:L483-91. 2010..These pathways, associated with the development of angioproliferative lesions as well as with the response to therapy in PAH, may provide new therapeutic targets... - Pulmonary arterial hypertension in congenital cardiac disease--the need for refinement of the Evian-Venice classificationMirjam E van Albada
Department of Paediatric and Congenital Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands
Cardiol Young 18:10-7. 2008..In addition, we discuss briefly the data currently available on the effectiveness of the new anti-proliferative drugs in patients with the Eisenmenger syndrome... - Clinical characterization of pediatric pulmonary hypertension: complex presentation and diagnosisRosa Laura E van Loon
Department of Pediatric Cardiology, University Medical Center, University of Groningen, Groningen, The Netherlands
J Pediatr 155:176-82.e1. 2009..To describe the clinical presentation of pediatric pulmonary arterial hypertension (PAH) and the intricacies of how to classify pediatric PAH according to the Venice classification... - Pulmonary vascular remodeling in congenital heart disease: enhanced expression of heat shock proteinsRalph Geiger
Department of Pediatric Cardiology, Center For Congenital Heart Diseases, University Medical Center Groningen, University of Groningen
Indian J Biochem Biophys 46:482-90. 2009..HSP-27 and HSP-70 are increasingly expressed in the advanced proliferative lesions of this disease... - Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: does the beneficial effect persist?Rosa Laura E van Loon
Department of Pediatrics, Division of Pediatric Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am Heart J 154:776-82. 2007..Data on long-term response to bosentan in adults and especially children with pulmonary arterial hypertension (PAH) associated with systemic-to-pulmonary shunt are scarce... - Low complication rates with totally implantable access port use in epoprostenol treatment of pulmonary hypertensionMichael G Dickinson
Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
J Heart Lung Transplant 28:273-9. 2009..In this study, we aimed to outline the complications associated with the use of a totally implantable access port (TIAP) and their consequences in continuous intravenous epoprostenol treatment... - Outcome of pediatric patients with pulmonary arterial hypertension in the era of new medical therapiesRosa Laura E van Loon
Department of Pediatric Cardiology, University Medical Center Groningen, Groningen, The Netherlands
Am J Cardiol 106:117-24. 2010..Start of second-generation drugs initially induced clinical improvements, but these effects decreased after longer follow-up...