Rolf M F Berger

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. pmc Clinical features of paediatric pulmonary hypertension: a registry study
    Rolf M F Berger
    Centre for Congenital Heart Diseases Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Netherlands
    Lancet 379:537-46. 2012
  2. doi request reprint Identification of treatment goals in paediatric pulmonary arterial hypertension
    Mark Jan Ploegstra
    Center For Congenital Heart Diseases, Dept of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur Respir J 44:1616-26. 2014
  3. doi request reprint Pediatric pulmonary hypertension in the Netherlands: epidemiology and characterization during the period 1991 to 2005
    Rosa Laura E van Loon
    Department of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Circulation 124:1755-64. 2011
  4. doi request reprint Prognostic factors in pediatric pulmonary arterial hypertension: A systematic review and meta-analysis
    Mark Jan Ploegstra
    Centre for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, The Netherlands Electronic address
    Int J Cardiol 184:198-207. 2015
  5. doi request reprint Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children s Hospital, The Netherlands Cardiovascular Center laboratory for Experimental Cardiology, Graduate School of Medical Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Electronic address
    J Mol Cell Cardiol 79:244-53. 2015
  6. doi request reprint Left ventricular outflow tract obstruction: should cardiac screening be offered to first-degree relatives?
    Wilhelmina S Kerstjens-Frederikse
    Department of Genetics, University Medical Centre Groningen, Groningen, The Netherlands
    Heart 97:1228-32. 2011
  7. ncbi request reprint Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension
    Mirjam E van Albada
    Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Pharmacol 549:107-16. 2006
  8. doi request reprint Pulse densitometer indocyanine green dilution curves: a simple applicable and accurate method for determination of cardiac shunts
    Arend Bergstra
    Thorax Center Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Congenit Heart Dis 4:362-8. 2009
  9. doi request reprint Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysis
    Rolf M F Berger
    University Medical Center, University of Groningen, Groningen, The Netherlands
    Int J Cardiol 144:373-8. 2010
  10. doi request reprint Menstrual cycle and its disorders in women with congenital heart disease
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Congenit Heart Dis 3:277-83. 2008

Collaborators

Detail Information

Publications28

  1. pmc Clinical features of paediatric pulmonary hypertension: a registry study
    Rolf M F Berger
    Centre for Congenital Heart Diseases Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Netherlands
    Lancet 379:537-46. 2012
    ..The Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension (TOPP) registry is a global, prospective study designed to provide information about demographics, treatment, and outcomes in paediatric pulmonary hypertension...
  2. doi request reprint Identification of treatment goals in paediatric pulmonary arterial hypertension
    Mark Jan Ploegstra
    Center For Congenital Heart Diseases, Dept of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur Respir J 44:1616-26. 2014
    ..The identification of these variables allows for the introduction of goal-oriented treatment strategies in paediatric PAH. ..
  3. doi request reprint Pediatric pulmonary hypertension in the Netherlands: epidemiology and characterization during the period 1991 to 2005
    Rosa Laura E van Loon
    Department of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Circulation 124:1755-64. 2011
    ..This study describes the nationwide epidemiological features of pediatric PH in the Netherlands during a 15-year period and the clinical course of pediatric PAH...
  4. doi request reprint Prognostic factors in pediatric pulmonary arterial hypertension: A systematic review and meta-analysis
    Mark Jan Ploegstra
    Centre for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, The Netherlands Electronic address
    Int J Cardiol 184:198-207. 2015
    ..The aim of this study was to identify and evaluate prognostic factors in pediatric PAH by a systematic review of the literature and to summarize the prognostic value of currently reported prognostic factors using meta-analysis...
  5. doi request reprint Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction
    Marinus A J Borgdorff
    Center For Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children s Hospital, The Netherlands Cardiovascular Center laboratory for Experimental Cardiology, Graduate School of Medical Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Electronic address
    J Mol Cell Cardiol 79:244-53. 2015
    ..The mechanisms of RVF are unknown. We used an experimental approach based upon clinical signs of RVF to delineate functional and biological processes associated with RVF...
  6. doi request reprint Left ventricular outflow tract obstruction: should cardiac screening be offered to first-degree relatives?
    Wilhelmina S Kerstjens-Frederikse
    Department of Genetics, University Medical Centre Groningen, Groningen, The Netherlands
    Heart 97:1228-32. 2011
    ..To determine whether offering cardiac screening to relatives of patients with left ventricular outflow tract obstructions (LVOTOs) would be justified...
  7. ncbi request reprint Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension
    Mirjam E van Albada
    Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Eur J Pharmacol 549:107-16. 2006
    ..However, these effects may be attributed to effects on cardiac rather than on pulmonary vascular remodeling...
  8. doi request reprint Pulse densitometer indocyanine green dilution curves: a simple applicable and accurate method for determination of cardiac shunts
    Arend Bergstra
    Thorax Center Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Congenit Heart Dis 4:362-8. 2009
    ..We therefore investigated the feasibility of a new technique, non-invasive pulse densitometry (PD) in patients with intracardiac shunts and compared its results with the established standards: cuvette densitometry (CD) and oximetry (OX)...
  9. doi request reprint Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysis
    Rolf M F Berger
    University Medical Center, University of Groningen, Groningen, The Netherlands
    Int J Cardiol 144:373-8. 2010
    ..We compared the effects of bosentan and placebo in patients with isolated ASD (ASD subgroup) versus patients with isolated VSD or both defects (VSD subgroup)...
  10. doi request reprint Menstrual cycle and its disorders in women with congenital heart disease
    Willem Drenthen
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Congenit Heart Dis 3:277-83. 2008
    ..To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD)...
  11. ncbi request reprint Severe pregnancy-induced deterioration of truncal valve regurgitation in an adolescent patient with repaired truncus arteriosus
    Elke S Hoendermis
    Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Cardiology 109:177-9. 2008
    ..Despite severe and symptomatic deterioration of truncal valve regurgitation, she successfully delivered a healthy child, and the valve function recovered within 2 weeks postpartum...
  12. doi request reprint Biological serum markers in the management of pediatric pulmonary arterial hypertension
    Mirjam E van Albada
    Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
    Pediatr Res 63:321-7. 2008
    ..The data indicate that these markers can be used to monitor treatment effects and predict mortality in pediatric PAH...
  13. ncbi request reprint Treprostinil in advanced experimental pulmonary hypertension: beneficial outcome without reversed pulmonary vascular remodeling
    Mirjam E van Albada
    Department of Pediatrics, Division of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Cardiovasc Pharmacol 48:249-54. 2006
    ..Although regression of pulmonary vascular remodeling has been suggested as therapeutic mechanism, its mode of action remains unknown...
  14. doi request reprint Drug management of fetal tachyarrhythmias: are we ready for a systematic and evidence-based approach?
    Freek van den Heuvel
    Department of Pediatric Cardiology, Beatrix Childrens Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
    Pacing Clin Electrophysiol 31:S54-7. 2008
    ..An international registry is proposed as an important step toward obtaining the necessary data to develop evidence-based management strategies...
  15. ncbi request reprint Persistent pulmonary hypertension of the newborn with transposition of the great arteries
    Marcus T R Roofthooft
    Department of Paediatric Cardiology, Beatrix Children s Hospital, Groningen, The Netherlands
    Ann Thorac Surg 83:1446-50. 2007
    ..However, data on its incidence and prognosis are scarce and originate mostly from the era before introduction of inhaled nitric oxide (iNO) therapy for PPHN...
  16. pmc Down syndrome and aberrant right subclavian artery
    Marcus T R Roofthooft
    Department of Paediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9700, Groningen, The Netherlands
    Eur J Pediatr 167:1033-6. 2008
    ..The presence of ARSA is not synonymous to the cause of feeding problems in patients with DS and corrective surgery of this vascular anomaly should be restricted to selected cases...
  17. doi request reprint Gene expression profile in flow-associated pulmonary arterial hypertension with neointimal lesions
    Mirjam E van Albada
    Center for Congenital Heart Disease, Beatrix Children s Hospital, Groningen, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 298:L483-91. 2010
    ..These pathways, associated with the development of angioproliferative lesions as well as with the response to therapy in PAH, may provide new therapeutic targets...
  18. doi request reprint Survival differences in pediatric pulmonary arterial hypertension: clues to a better understanding of outcome and optimal treatment strategies
    Willemijn M H Zijlstra
    Center For Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Am Coll Cardiol 63:2159-69. 2014
    ....
  19. doi request reprint Pulmonary arterial hypertension in congenital cardiac disease--the need for refinement of the Evian-Venice classification
    Mirjam E van Albada
    Department of Paediatric and Congenital Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands
    Cardiol Young 18:10-7. 2008
    ..In addition, we discuss briefly the data currently available on the effectiveness of the new anti-proliferative drugs in patients with the Eisenmenger syndrome...
  20. doi request reprint Sildenafil treatment in established right ventricular dysfunction improves diastolic function and attenuates interstitial fibrosis independent from afterload
    Marinus A Borgdorff
    Center For Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children s Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands and
    Am J Physiol Heart Circ Physiol 307:H361-9. 2014
    ..These results indicate that sildenafil treatment has therapeutic potential for established RV dysfunction. ..
  21. doi request reprint The challenges in paediatric pulmonary arterial hypertension
    Maurice Beghetti
    Paediatric Cardiology Unit, Children s University Hospital Geneva, Geneva, Switzerland Centre for Congenital Heart Diseases, Dept of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Eur Respir Rev 23:498-504. 2014
    ....
  22. doi request reprint Ventricular remodelling after pulmonary valve replacement: comparison between pressure-loaded and volume-loaded right ventricles
    Thomas M Gorter
    Department of Pediatric Cardiology, Center For Congenital Heart Diseases, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Netherlands
    Interact Cardiovasc Thorac Surg 19:95-101. 2014
    ..PVR thereby decreases the progression of RV dilatation and/or hypertrophy. This study investigates RV remodelling patterns after PVR in patients with either pressure, volume or combined volume- and pressure-loaded RVs...
  23. doi request reprint Current and advancing treatments for pulmonary arterial hypertension in childhood
    Willemijn M H Zijlstra
    Center For Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Expert Rev Respir Med 8:615-28. 2014
    ..We also discuss potential treatment goals and how the available data can be translated into treatment strategies in pediatric PAH. ..
  24. doi request reprint Clinical characterization of pediatric pulmonary hypertension: complex presentation and diagnosis
    Rosa Laura E van Loon
    Department of Pediatric Cardiology, University Medical Center, University of Groningen, Groningen, The Netherlands
    J Pediatr 155:176-82.e1. 2009
    ..To describe the clinical presentation of pediatric pulmonary arterial hypertension (PAH) and the intricacies of how to classify pediatric PAH according to the Venice classification...
  25. doi request reprint Low complication rates with totally implantable access port use in epoprostenol treatment of pulmonary hypertension
    Michael G Dickinson
    Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, The Netherlands
    J Heart Lung Transplant 28:273-9. 2009
    ..In this study, we aimed to outline the complications associated with the use of a totally implantable access port (TIAP) and their consequences in continuous intravenous epoprostenol treatment...
  26. ncbi request reprint Pulmonary vascular remodeling in congenital heart disease: enhanced expression of heat shock proteins
    Ralph Geiger
    Department of Pediatric Cardiology, Center For Congenital Heart Diseases, University Medical Center Groningen, University of Groningen
    Indian J Biochem Biophys 46:482-90. 2009
    ..HSP-27 and HSP-70 are increasingly expressed in the advanced proliferative lesions of this disease...
  27. ncbi request reprint Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: does the beneficial effect persist?
    Rosa Laura E van Loon
    Department of Pediatrics, Division of Pediatric Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Am Heart J 154:776-82. 2007
    ..Data on long-term response to bosentan in adults and especially children with pulmonary arterial hypertension (PAH) associated with systemic-to-pulmonary shunt are scarce...
  28. doi request reprint Outcome of pediatric patients with pulmonary arterial hypertension in the era of new medical therapies
    Rosa Laura E van Loon
    Department of Pediatric Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    Am J Cardiol 106:117-24. 2010
    ..Start of second-generation drugs initially induced clinical improvements, but these effects decreased after longer follow-up...