Research Topics
| Roos E BarthSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Rapid accumulation of nonnucleoside reverse transcriptase inhibitor-associated resistance: evidence of transmitted resistance in rural South AfricaRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
AIDS 22:2210-2. 2008..Importantly, monitoring of HIV-RNA and prompt switch of treatment may prevent development of thymidine analogue-associated mutations...
Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: a systematic reviewRoos E Barth
University Medical Centre Utrecht, Department of Internal Medicine and Infectious Diseases, Netherlands
Lancet Infect Dis 10:155-66. 2010....
Long-term outcome of children receiving antiretroviral treatment in rural South Africa: substantial virologic failure on first-line treatmentRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
Pediatr Infect Dis J 30:52-6. 2011..Data from rural areas are especially scarce. The aim of this study was to evaluate the long-term virologic outcome of a pediatric cohort in rural South Africa...
Hepatitis B/C and HIV in sub-Saharan Africa: an association between highly prevalent infectious diseases. A systematic review and meta-analysisRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, F02 126, Postbus 85500, 3508 GA Utrecht, The Netherlands
Int J Infect Dis 14:e1024-31. 2010..The aim of this review was to determine the prevalence of HBV and HCV in HIV-infected patients in sub-Saharan Africa and to analyze whether HIV is associated with a higher HBV/HCV prevalence in that region...
'To bead or not to bead?' Treatment of osteomyelitis and prosthetic joint-associated infections with gentamicin bead chainsRoos E Barth
University Medical Centre Utrecht, Department of Internal Medicine and Infectious Diseases, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
Int J Antimicrob Agents 38:371-5. 2011..It is concluded that more well-executed, prospective studies are needed to settle the discussion on the use of gentamicin-containing beads in the treatment of orthopaedic infections...
Presence of occult HBV, but near absence of active HBV and HCV infections in people infected with HIV in rural South AfricaRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
J Med Virol 83:929-34. 2011..Local HBV/HCV prevalence data are needed to optimize vaccination and antiretroviral treatment strategies. Occult HBV in patients with HIV may be missed regularly when molecular analyses are not available...
Accumulation of drug resistance and loss of therapeutic options precede commonly used criteria for treatment failure in HIV-1 subtype-C-infected patientsRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
Antivir Ther 17:377-86. 2012..Here, accumulation of resistance and consequences for second-line therapy were investigated in African HIV-1 subtype-C-infected patients...
Sustained virological response on second-line antiretroviral therapy following virological failure in HIV-infected patients in rural South AfricaAnnelot F Schoffelen
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands
PLoS ONE 8:e58526. 2013..This study aims to describe the virological, immunological and clinical efficacy of protease inhibitor (PI)-based second-line antiretroviral therapy (ART) in rural South Africa...
Long-Term Outcome of an HIV-Treatment Programme in Rural Africa: Viral Suppression despite Early MortalityRoos E Barth
Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, F02 126, Postbus 85500, 3508 GA Utrecht, The Netherlands
AIDS Res Treat 2011:434375. 2011..Continued efforts are needed to enrol patients earlier. Furthermore, the observed viro-immunological dissociation emphasises the need to make HIV-RNA testing more widely available...
Interferon-gamma release assays (IGRAs) in high-endemic settings: could they play a role in optimizing global TB diagnostics? Evaluating the possibilities of using IGRAs to diagnose active TB in a rural African settingRoos E Barth
University Medical Centre Utrecht, Department of Internal Medicine and Infectious Diseases and Eijkman Winkler Institute for Medical Microbiology and Infectious Diseases, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Int J Infect Dis 12:e1-6. 2008..As these settings are the ones that suffer the most from the TB epidemic, we believe that the role of IGRAs in global TB control is questionable...
