S C Bakker

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q
    S C Bakker
    Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Hum Genet 72:1251-60. 2003
  2. ncbi The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophrenia
    S C Bakker
    Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
    Genes Brain Behav 6:113-9. 2007
  3. ncbi An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia
    B J Jungerius
    Complex Genetics Section, DBG Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Mol Psychiatry 13:1060-8. 2008
  4. doi Schizophrenia genetic variants are not associated with intelligence
    A F Terwisscha van Scheltinga
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Psychol Med 43:2563-70. 2013
  5. doi Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid
    J J Luykx
    1 Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands 2 Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Mol Psychiatry 19:228-34. 2014
  6. doi Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findings
    J J Luykx
    Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurosci Biobehav Rev 36:198-205. 2012
  7. ncbi Neuregulin 1: genetic support for schizophrenia subtypes
    S C Bakker
    Mol Psychiatry 9:1061-3. 2004
  8. ncbi Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13
    M N Ogdie
    Mol Psychiatry 11:5-8. 2006

Collaborators

Detail Information

Publications8

  1. pmc A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q
    S C Bakker
    Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Am J Hum Genet 72:1251-60. 2003
    ..04 and 2.05 were found for chromosome regions 7p and 9q in the narrow phenotype. Except for a region on chromosome 5, no overlap was found with regions mentioned in the only other independent genome scan in ADHD reported to date...
  2. ncbi The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophrenia
    S C Bakker
    Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
    Genes Brain Behav 6:113-9. 2007
    ..In conclusion, our data provide further evidence that specific genes may be involved in different schizophrenia subtypes and suggest that the PIP5K2A gene deserves further study as a general susceptibility gene for schizophrenia...
  3. ncbi An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia
    B J Jungerius
    Complex Genetics Section, DBG Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Mol Psychiatry 13:1060-8. 2008
    ..01). Our approach--of screening genes involved in a particular pathway for association--resulted in identification of several, mostly novel, genes associated with the risk of developing schizophrenia in the Dutch population...
  4. doi Schizophrenia genetic variants are not associated with intelligence
    A F Terwisscha van Scheltinga
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Psychol Med 43:2563-70. 2013
    ..Therefore, we hypothesized that genetic variants associated with schizophrenia, including copy number variants (CNVs) and a polygenic schizophrenia (risk) score (PSS), may influence intelligence...
  5. doi Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid
    J J Luykx
    1 Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands 2 Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
    Mol Psychiatry 19:228-34. 2014
    ..These findings will hopefully contribute to an exploration of the functional impact of the highlighted genes on monoaminergic transmission and neuropsychiatric phenotypes...
  6. doi Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findings
    J J Luykx
    Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurosci Biobehav Rev 36:198-205. 2012
    ..These results fit the central role of the ACC in depressive symptomatology and suggest that in MDD changes in glutamatergic neurotransmission are state-dependent...
  7. ncbi Neuregulin 1: genetic support for schizophrenia subtypes
    S C Bakker
    Mol Psychiatry 9:1061-3. 2004
  8. ncbi Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13
    M N Ogdie
    Mol Psychiatry 11:5-8. 2006