Research Topics
Genomes and Genes | S C BakkerSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15qS C Bakker
Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Hum Genet 72:1251-60. 2003..04 and 2.05 were found for chromosome regions 7p and 9q in the narrow phenotype. Except for a region on chromosome 5, no overlap was found with regions mentioned in the only other independent genome scan in ADHD reported to date...
The PIP5K2A and RGS4 genes are differentially associated with deficit and non-deficit schizophreniaS C Bakker
Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
Genes Brain Behav 6:113-9. 2007..In conclusion, our data provide further evidence that specific genes may be involved in different schizophrenia subtypes and suggest that the PIP5K2A gene deserves further study as a general susceptibility gene for schizophrenia...
An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophreniaB J Jungerius
Complex Genetics Section, DBG Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
Mol Psychiatry 13:1060-8. 2008..01). Our approach--of screening genes involved in a particular pathway for association--resulted in identification of several, mostly novel, genes associated with the risk of developing schizophrenia in the Dutch population...
Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findingsJ J Luykx
Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
Neurosci Biobehav Rev 36:198-205. 2012..These results fit the central role of the ACC in depressive symptomatology and suggest that in MDD changes in glutamatergic neurotransmission are state-dependent...
Neuregulin 1: genetic support for schizophrenia subtypesS C Bakker
Mol Psychiatry 9:1061-3. 2004
Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13M N Ogdie
Mol Psychiatry 11:5-8. 2006
