Andre Aleman

Summary

Affiliation: University Medical Center Groningen
Country: The Netherlands

Publications

  1. ncbi request reprint Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a meta-analysis
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    J Clin Psychiatry 68:416-21. 2007
  2. doi request reprint Brain imaging, genetics and emotion
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Biol Psychol 79:58-69. 2008
  3. doi request reprint Bidirectional information flow in frontoamygdalar circuits in humans: a dynamic causal modeling study of emotional associative learning
    Branislava Curcic-Blake
    Cognitive Neuropsychiatry Group, Department of Neuroscience, Neuroimaging Center, University Medical Center Groningen, University of Groningen, 9713AW Groningen, The Netherlands
    Cereb Cortex 22:436-45. 2012
  4. pmc REFLEX, a social-cognitive group treatment to improve insight in schizophrenia: study protocol of a multi-center RCT
    G H M Pijnenborg
    Dept of Psychotic Disorders, GGZ Drenthe, Dennenweg 9, 9404 LA, Assen, The Netherlands
    BMC Psychiatry 11:161. 2011
  5. pmc Sex differences in neural activation to facial expressions denoting contempt and disgust
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 3:e3622. 2008
  6. doi request reprint Insights into hallucinations in schizophrenia: novel treatment approaches
    Andre Aleman
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, The Netherlands
    Expert Rev Neurother 11:1007-15. 2011
  7. doi request reprint Repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex disrupts digit span task performance
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neuropsychobiology 57:44-8. 2008
  8. doi request reprint Circulating insulin-like growth factor I and cognitive function: neuromodulation throughout the lifespan
    Andre Aleman
    Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands Department of Psychology, University of Groningen, Groningen, The Netherlands
    Prog Neurobiol 89:256-65. 2009
  9. ncbi request reprint Feelings you can't imagine: towards a cognitive neuroscience of alexithymia
    Andre Aleman
    BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    Trends Cogn Sci 9:553-5. 2005
  10. ncbi request reprint Strange feelings: do amygdala abnormalities dysregulate the emotional brain in schizophrenia?
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, A Deusinglaan 2, 9713 AW Groningen, The Netherlands
    Prog Neurobiol 77:283-98. 2005

Collaborators

Detail Information

Publications67

  1. ncbi request reprint Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a meta-analysis
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    J Clin Psychiatry 68:416-21. 2007
    ..Several studies have now been reported regarding the efficacy of TMS treatment, but results were inconsistent. Therefore, meta-analytic integration of the published trials is needed to evaluate the prospects of this new treatment...
  2. doi request reprint Brain imaging, genetics and emotion
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Biol Psychol 79:58-69. 2008
    ....
  3. doi request reprint Bidirectional information flow in frontoamygdalar circuits in humans: a dynamic causal modeling study of emotional associative learning
    Branislava Curcic-Blake
    Cognitive Neuropsychiatry Group, Department of Neuroscience, Neuroimaging Center, University Medical Center Groningen, University of Groningen, 9713AW Groningen, The Netherlands
    Cereb Cortex 22:436-45. 2012
    ..This circuit (especially for negative stimuli) converges with emotion regulation circuits. The enhancement in the connectivity might be responsible for the emotional memory effect in this type of learning...
  4. pmc REFLEX, a social-cognitive group treatment to improve insight in schizophrenia: study protocol of a multi-center RCT
    G H M Pijnenborg
    Dept of Psychotic Disorders, GGZ Drenthe, Dennenweg 9, 9404 LA, Assen, The Netherlands
    BMC Psychiatry 11:161. 2011
    ..REFLEX is a 12-sessions group training, consisting of three modules of four sessions each. Modules in this intervention are: "coping with stigma", "you and your personal narrative", and "you in the present"...
  5. pmc Sex differences in neural activation to facial expressions denoting contempt and disgust
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 3:e3622. 2008
    ..Thus, our results suggest a neural basis for sex differences in moral sensitivity regarding hierarchy on the one hand and physical purity on the other...
  6. doi request reprint Insights into hallucinations in schizophrenia: novel treatment approaches
    Andre Aleman
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, The Netherlands
    Expert Rev Neurother 11:1007-15. 2011
    ..After a brief discussion of these approaches, we take stock of recent advances and discuss avenues for future research...
  7. doi request reprint Repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex disrupts digit span task performance
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neuropsychobiology 57:44-8. 2008
    ..This effect of rTMS did not differ between digits forward and digits backward. Our results suggest that the right DLPFC is critical for central executive processes utilized by the digits forward and backward tasks...
  8. doi request reprint Circulating insulin-like growth factor I and cognitive function: neuromodulation throughout the lifespan
    Andre Aleman
    Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands Department of Psychology, University of Groningen, Groningen, The Netherlands
    Prog Neurobiol 89:256-65. 2009
    ..The role of IGF-I in synaptic plasticity render its neurotrophic potential a key target for remediating the cognitive impairment associated with a range of neurological conditions...
  9. ncbi request reprint Feelings you can't imagine: towards a cognitive neuroscience of alexithymia
    Andre Aleman
    BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    Trends Cogn Sci 9:553-5. 2005
    ..This finding augments the emerging understanding of the neural basis of alexithymia, and potentially provides valuable insights into brain systems underlying normal emotion processing...
  10. ncbi request reprint Strange feelings: do amygdala abnormalities dysregulate the emotional brain in schizophrenia?
    Andre Aleman
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, A Deusinglaan 2, 9713 AW Groningen, The Netherlands
    Prog Neurobiol 77:283-98. 2005
    ..We also hypothesize that the central and basolateral nuclei of the amygdala may contribute differentially to these abnormalities...
  11. ncbi request reprint How to fill a half-full glass: emotion and schizophrenia
    Andre Aleman
    University of Groningen, Groningen, Netherlands
    Am Psychol 61:75-6. 2006
  12. ncbi request reprint Insight in psychosis and neuropsychological function: meta-analysis
    Andre Aleman
    BCN Neuroimaging Centre, University Medical Centre Groningen, The Netherlands, and Department of Neuropsychiatry, St George s Hospital, London, UK
    Br J Psychiatry 189:204-12. 2006
    ..One factor contributing to impaired awareness of illness (poor insight) in psychotic disorders may be neurocognitive deficits...
  13. doi request reprint Insight in bipolar disorder: associations with cognitive and emotional processing and illness characteristics
    Marieke J van der Werf-Eldering
    Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands
    Bipolar Disord 13:343-54. 2011
    ..To investigate the multifactorial relationship between illness insight, cognitive and emotional processes, and illness characteristics in bipolar disorder patients...
  14. doi request reprint Functional connectivity of the temporo-parietal region in schizophrenia: effects of rTMS treatment of auditory hallucinations
    Ans Vercammen
    Department of Neuroscience, University Medical Center Groningen, The Netherlands
    J Psychiatr Res 44:725-31. 2010
    ..However, the relationship between these functional changes during the resting state and the rate of clinical improvement needs further clarification...
  15. pmc Altered resting state connectivity of the default mode network in alexithymia
    Edith J Liemburg
    Neuroimaging Center, Antonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands
    Soc Cogn Affect Neurosci 7:660-6. 2012
    ..On the other hand, alexithymia was associated with stronger functional connections of the DMN with brain areas involved in sensory input and control of emotion...
  16. doi request reprint Emotion regulation strategies in patients with schizophrenia
    Lisette van der Meer
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Psychiatry Res 170:108-13. 2009
    ..These difficulties were related to symptoms of depression. Interventions specifically targeted at affect regulation and recognition of emotional state could promote emotional well-being in schizophrenia patients...
  17. doi request reprint Altered activation and functional connectivity of neural systems supporting cognitive control of emotion in psychosis proneness
    Gemma Modinos
    Department of Neuroscience, University Medical Center Groningen, and BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    Schizophr Res 118:88-97. 2010
    ..These findings extend the hypothesis of emotion dysregulation in schizophrenia to PP, and suggest that emotion regulation difficulties may be at the core of a vulnerability to psychosis...
  18. pmc Reduced connectivity in the self-processing network of schizophrenia patients with poor insight
    Edith J Liemburg
    Department of Neuroscience, University Medical Center Groningen and BCN NeuroImaging Center, University of Groningen, Groningen, The Netherlands
    PLoS ONE 7:e42707. 2012
    ..This finding is compatible with theories implying a role of reduced self-referential processing as a mechanism contributing to poor insight...
  19. doi request reprint The nature of affective priming in music and speech
    Katharina Sophia Goerlich
    University of Groningen, The Netherlands
    J Cogn Neurosci 24:1725-41. 2012
    ..The present data further suggest a role of response competition during the affective categorization of music, prosody, and words with emotional connotations...
  20. pmc Structural covariance in the hallucinating brain: a voxel-based morphometry study
    Gemma Modinos
    BCN Neuroimaging Center, Department of Neuroscience, University of Groningen, Groningen, The Netherlands
    J Psychiatry Neurosci 34:465-9. 2009
    ..We used voxel-based morphometry to examine regional grey matter volumes and structural covariance associated with severity of auditory verbal hallucinations...
  21. pmc Subjective loudness and reality of auditory verbal hallucinations and activation of the inner speech processing network
    Ans Vercammen
    Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands
    Schizophr Bull 37:1009-16. 2011
    ..We aimed to assess whether subjective perceptual and experiential characteristics may be linked to neural activation in the inner speech processing network...
  22. pmc Can variation in hypothalamic-pituitary-adrenal (HPA)-axis activity explain the relationship between depression and cognition in bipolar patients?
    Marieke J van der Werf-Eldering
    Department of Psychiatry, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 7:e37119. 2012
    ..This study examined whether variation in HPA axis activity underlies the association between mood symptoms and cognitive functioning...
  23. doi request reprint Abnormal connectivity between attentional, language and auditory networks in schizophrenia
    Edith J Liemburg
    Department of Neuroscience, University Medical Center Groningen, and BCN Neuroimaging Center, University of Groningen, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands
    Schizophr Res 135:15-22. 2012
    ..This altered connectivity pattern appears to be present independent of symptom severity, and may be suggestive of a trait, rather than a state characteristic...
  24. doi request reprint Auditory hallucinations in schizophrenia are associated with reduced functional connectivity of the temporo-parietal area
    Ans Vercammen
    Department of Neuroscience, University Medical Center Groningen, BCN Neuroimaging Center, University of Groningen, The Netherlands
    Biol Psychiatry 67:912-8. 2010
    ....
  25. pmc Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion
    Gemma Modinos
    University Medical Center Groningen, Department of Neuroscience, University of Groningen, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands
    Soc Cogn Affect Neurosci 5:369-77. 2010
    ....
  26. doi request reprint Functional magnetic resonance imaging correlates of emotional word encoding and recognition in depression and anxiety disorders
    Marie Jose van Tol
    Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Biol Psychiatry 71:593-602. 2012
    ....
  27. doi request reprint Neurobiological correlates of theory of mind in psychosis proneness
    Gemma Modinos
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neuropsychologia 48:3715-24. 2010
    ..These results suggest that subjects with positive-dimension PP require more activation of prefrontal areas to adequately mentalize. Differences in the neural mechanisms underlying ToM might be associated with vulnerability to psychosis...
  28. pmc Psychosis-proneness and neural correlates of self-inhibition in theory of mind
    Lisette van der Meer
    Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands
    PLoS ONE 8:e67774. 2013
    ..This may reflect a compensatory mechanism, which may no longer be available for patients with schizophrenia-spectrum disorders resulting in ToM impairments. ..
  29. pmc When Broca goes uninformed: reduced information flow to Broca's area in schizophrenia patients with auditory hallucinations
    Branislava Curcic-Blake
    Department of Neuroscience, University of Groningen, Groningen, The Netherlands
    Schizophr Bull 39:1087-95. 2013
    ..In addition, a lack of synchronization between Broca and its homolog may lead to the erroneous interpretation of emotional speech activity from the right hemisphere as coming from an external source. ..
  30. doi request reprint Antipsychotic medication and prefrontal cortex activation: a review of neuroimaging findings
    Edith J Liemburg
    Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 2 9713 AW Groningen, The Netherlands
    Eur Neuropsychopharmacol 22:387-400. 2012
    ....
  31. pmc Results of a pilot study on the involvement of bilateral inferior frontal gyri in emotional prosody perception: an rTMS study
    Marjolijn Hoekert
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 2, PO Box 196, 9700 AD Groningen, The Netherlands
    BMC Neurosci 11:93. 2010
    ..In the semantics condition an emotion (fear, anger or neutral) was expressed in the content pronounced with a neutral intonation. In the prosody condition the emotion was expressed in the intonation, while the content was neutral...
  32. pmc Insight in psychosis: relationship with neurocognition, social cognition and clinical symptoms depends on phase of illness
    Piotr J Quee
    Department of Psychiatry and Rob Giel Research Center, University Medical Center Groningen, Groningen, The Netherlands
    Schizophr Bull 37:29-37. 2011
    ..This supports theories that imply a role for deficient emotion recognition and mentalizing in reduced insight. Further studies need to investigate insight in ROP into more detail...
  33. doi request reprint COMT Val158Met polymorphism, verbalizing of emotion and activation of affective brain systems
    Marte Swart
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, Postbus 196, 9700 AD Groningen, The Netherlands
    Neuroimage 55:338-44. 2011
    ..We conclude that the Met allele modulates neural activation in regions associated with emotional awareness. Our findings may contribute to understanding the neural correlates of susceptibility for affective disorders...
  34. ncbi request reprint The hallucinating brain: a review of structural and functional neuroimaging studies of hallucinations
    Paul Allen
    Kings College London, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, London, UK
    Neurosci Biobehav Rev 32:175-91. 2008
    ..Based on the findings of these studies we tentatively propose a neurocognitive model in which both bottom-up and top-down processes interact to produce these erroneous percepts. Finally, directions for future work are discussed...
  35. doi request reprint Two subdomains of negative symptoms in psychotic disorders: established and confirmed in two large cohorts
    Edith Liemburg
    Department of Neuroscience, and BCN Neuroimaging Center, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands
    J Psychiatr Res 47:718-25. 2013
    ..This factor structure supports the DSM-V classification and may be relevant for pathophysiology and treatment of schizophrenia and other psychotic disorders...
  36. pmc Influence of COMT val158met genotype on the depressed brain during emotional processing and working memory
    Esther M Opmeer
    Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
    PLoS ONE 8:e73290. 2013
    ..These results demonstrate that COMT genotype is associated with relevant endophenotypes for MDD. In addition, presence of MDD only interacts with genotype during emotional processing and not working memory. ..
  37. doi request reprint Neural correlates of alexithymia: a meta-analysis of emotion processing studies
    Jorien van der Velde
    Neuroimaging Center, University Medical Center Groningen, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands Electronic address
    Neurosci Biobehav Rev 37:1774-85. 2013
    ..These results suggest valence-specific as well as valence-independent effects of alexithymia on the neural processing of emotions. ..
  38. ncbi request reprint Dissecting the cognitive and neural basis of emotional abnormalities
    Andre Aleman
    Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Cogn Neuropsychiatry 11:193-7. 2006
  39. doi request reprint The amygdala, top-down effects, and selective attention to features
    Richard H A H Jacobs
    University of Groningen, University Medical Center Groningen, Laboratory for Experimental Ophthalmology, School for Behavioral and Cognitive Neurosciences, 9700 RB Groningen, The Netherlands
    Neurosci Biobehav Rev 36:2069-84. 2012
    ..Our hypothesis results in the testable prediction that the amygdala is involved when searching for stimuli based on their feature information, but not when searching for stimuli based on spatial cues...
  40. pmc The sound of feelings: electrophysiological responses to emotional speech in alexithymia
    Katharina Sophia Goerlich
    Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 7:e36951. 2012
    ..We investigated the impact of both alexithymia dimensions on electrophysiological responses to emotional speech in 60 female subjects...
  41. pmc Semantic expectations can induce false perceptions in hallucination-prone individuals
    Ans Vercammen
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
    Schizophr Bull 36:151-6. 2010
    ..We conclude that aberrant top-down processing, particularly in the form of strong semantic expectations, may contribute to the experience of auditory-verbal hallucinations...
  42. pmc Dealing with feelings: characterization of trait alexithymia on emotion regulation strategies and cognitive-emotional processing
    Marte Swart
    Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 4:e5751. 2009
    ..In order to shed light on the core deficit, we tested our subjects on a wide range of emotional tasks. We expected the high alexithymics to underperform on all tasks...
  43. doi request reprint Normal brain activation in schizophrenia patients during associative emotional learning
    Marte Swart
    Lentis Research, Lentis Center for Mental Healthcare, Groningen, The Netherlands
    Psychiatry Res 214:269-76. 2013
    ....
  44. doi request reprint The biological and psychological basis of neuroticism: current status and future directions
    Johan Ormel
    Department of Psychiatry and Interdisciplinary Center Psychopathology and Emotion regulation, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Neurosci Biobehav Rev 37:59-72. 2013
    ..We discuss potential methodological improvements and substantive directions for future research...
  45. pmc Impaired attribution of emotion to facial expressions in anxiety and major depression
    Liliana R Demenescu
    Department of Neuroscience, University Medical Center Groningen, BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    PLoS ONE 5:e15058. 2010
    ..There is a need to review and integrate the published literature on emotional expression recognition in anxiety disorders and major depression...
  46. doi request reprint Multivariate pattern classification reveals differential brain activation during emotional processing in individuals with psychosis proneness
    Gemma Modinos
    Department of Psychosis Studies, Institute of Psychiatry, King s College London, United Kingdom
    Neuroimage 59:3033-41. 2012
    ..Further application of this approach may aid in characterising people at clinical and genetic risk of developing psychosis...
  47. doi request reprint Inhibit yourself and understand the other: neural basis of distinct processes underlying Theory of Mind
    Lisette van der Meer
    University of Groningen, University Medical Center Groningen, Department of Neuroscience, Antonius Deusinglaan 2, P O Box 196, 9700 AD Groningen, The Netherlands
    Neuroimage 56:2364-74. 2011
    ..Furthermore, evidence for partially shared neural mechanisms for inhibition in complex social situations and basic motor response inhibition was found...
  48. doi request reprint Effects of bilateral repetitive transcranial magnetic stimulation on treatment resistant auditory-verbal hallucinations in schizophrenia: a randomized controlled trial
    Ans Vercammen
    Department of Neuroscience, University Medical Center Groningen and BCN NeuroImaging Center, University of Groningen, The Netherlands
    Schizophr Res 114:172-9. 2009
    ..This study aimed to investigate whether 1 Hz repetitive transcranial magnetic stimulation (rTMS) of the bilateral temporo-parietal region would lead to increased effectiveness in the management of AVH, compared to left rTMS or placebo...
  49. pmc Time course of the involvement of the right anterior superior temporal gyrus and the right fronto-parietal operculum in emotional prosody perception
    Marjolijn Hoekert
    BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    PLoS ONE 3:e2244. 2008
    ..This may reflect that emotional cues can still be ambiguous at the beginning of sentences, but become more apparent half-way through the sentence...
  50. doi request reprint Neuroticism and the brain: a quantitative meta-analysis of neuroimaging studies investigating emotion processing
    Michelle N Servaas
    Neuroimaging Center, Department of Neuroscience, University of Groningen University Medical Center Groningen, Antonius Deusinglaan 2, 9713 AW, Groningen, The Netherlands Electronic address
    Neurosci Biobehav Rev 37:1518-29. 2013
    ..Furthermore, the meta-analytic findings are incorporated into a general model of emotion processing in neuroticism. ..
  51. doi request reprint Emotional valence modulates brain functional abnormalities in depression: evidence from a meta-analysis of fMRI studies
    Nynke A Groenewold
    BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 37:152-63. 2013
    ..Emotional valence is a moderator of neural abnormalities in depression, and therefore a critical feature to consider in models of emotional dysfunction in depression...
  52. doi request reprint Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning
    Branislava Curcic-Blake
    Cognitive Neuropsychiatry Group, Department of Neuroscience, Neuroimaging Center NIC, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 2, 9713 AW Groningen, The Netherlands
    Neuroimage 59:1540-50. 2012
    ..We conclude that PPP1R1B is associated with the neural network involved in associative emotional learning...
  53. pmc Hearing feelings: affective categorization of music and speech in alexithymia, an ERP study
    Katharina Sophia Goerlich
    Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 6:e19501. 2011
    ..We investigated the neural signature of such emotional processing in alexithymia by means of event-related potentials...
  54. doi request reprint Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: review and meta-analysis
    Jozarni J Dlabac-de Lange
    Department of Pschiatry, University Medical Center Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
    J Clin Psychiatry 71:411-8. 2010
    ..During the past decade, several trials have reported on the efficacy of rTMS treatment; however, the results were inconsistent...
  55. doi request reprint Is the lack of association between cognitive complaints and objective cognitive functioning in patients with bipolar disorder moderated by depressive symptoms?
    Marieke J van der Werf-Eldering
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Affect Disord 130:306-11. 2011
    ..To investigate the association between cognitive complaints and objective cognitive functioning in bipolar patients, with a focus on the moderating role of depressive symptoms...
  56. pmc Activation of anterior insula during self-reflection
    Gemma Modinos
    BCN Neuroimaging Center, University of Groningen, Groningen, The Netherlands
    PLoS ONE 4:e4618. 2009
    ..However, although some studies reported involvement of the insula, little attention has been paid to this region as forming part of the "self"-network...
  57. doi request reprint A manual-based individual therapy to improve metacognition in schizophrenia: protocol of a multi-center RCT
    Rozanne J M van Donkersgoed
    Department of Clinical Psychology and Experimental Psychopathology, Faculty of Behavioral and Social Sciences, University of Groningen, Grote Kruisstraat 2 1, 9712 TS Groningen, The Netherlands
    BMC Psychiatry 14:27. 2014
    ....
  58. pmc A novel magnetic stimulator increases experimental pain tolerance in healthy volunteers - a double-blind sham-controlled crossover study
    Rudie Kortekaas
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    PLoS ONE 8:e61926. 2013
    ..In addition, the flexible configuration with small coils on a head cap improves clinical applicability...
  59. pmc The effect of criticism on functional brain connectivity and associations with neuroticism
    Michelle Nadine Servaas
    Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen University of Groningen, Groningen, The Netherlands
    PLoS ONE 8:e69606. 2013
    ..Furthermore, multiple aspects of emotion processing were found to be affected in individuals scoring higher on neuroticism during the processing of criticism, which may increase their sensitivity to negative social-evaluation. ..
  60. pmc Comparing cognitive and somatic symptoms of depression in myocardial infarction patients and depressed patients in primary and mental health care
    Nynke A Groenewold
    Interdisciplinary Center for Psychopathology and Emotion regulation, Department of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands
    PLoS ONE 8:e53859. 2013
    ..Future studies should investigate the etiological factors predictive of symptom dimensions in myocardial infarction and late-onset depression patients...
  61. ncbi request reprint Impaired recognition and expression of emotional prosody in schizophrenia: review and meta-analysis
    Marjolijn Hoekert
    BCN Neuroimaging Center, University of Groningen, University Medical Center Groningen, The Netherlands
    Schizophr Res 96:135-45. 2007
    ..In this report we focus on vocal emotion processing. This function bears upon two corner stones of social functioning, language and emotion, which have both been found to be impaired in schizophrenia...
  62. doi request reprint Self-reflection and the brain: a theoretical review and meta-analysis of neuroimaging studies with implications for schizophrenia
    Lisette van der Meer
    Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Neurosci Biobehav Rev 34:935-46. 2010
    ..Finally, implications of the model for schizophrenia and lack of insight are noted...
  63. doi request reprint Distinct associations of insula and cingulate volume with the cognitive and affective dimensions of alexithymia
    Katharina Sophia Goerlich-Dobre
    Neuroimaging Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Aachen 52074, Germany Electronic address
    Neuropsychologia 53:284-92. 2014
    ..These results suggest that the two alexithymia dimensions are associated with distinct structural correlates. ..
  64. doi request reprint Relationship between cognition, clinical and cognitive insight in psychotic disorders: a review and meta-analysis
    Akshay Nair
    NIHR Academic Clinical Fellow, South London and Maudsley NHS Foundation Trust, London, UK Institute of Psychiatry, King s College, London, UK Electronic address
    Schizophr Res 152:191-200. 2014
    ..These findings reflect the complexity of the insight construct and indicate that while the neurocognitive model is important it is likely to be one of many which contribute to the understanding of this phenomenon. ..
  65. doi request reprint Magnetic resonance spectroscopy in mild cognitive impairment: systematic review and meta-analysis
    Shankar Tumati
    Neuroimaging Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands Electronic address
    Neurosci Biobehav Rev 37:2571-86. 2013
    ..NAA/mI ratio was reduced in the PC. NAA may be the most reliable marker of brain dysfunction in MCI though mI, Cho, and Cr may also contribute towards this. ..
  66. doi request reprint Depression and the role of genes involved in dopamine metabolism and signalling
    Esther M Opmeer
    Department of Neuroscience, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Prog Neurobiol 92:112-33. 2010
    ..Two notable exceptions are the DRD4 and DAT gene: both have variable tandem repeat polymorphisms which may have a "single gene" influence on susceptibility to MDD...
  67. ncbi request reprint Inner speech models of auditory verbal hallucinations: evidence from behavioural and neuroimaging studies
    Paul Allen
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, De Crespigny Park, Denmark Hill, King s College, London, UK
    Int Rev Psychiatry 19:407-15. 2007
    ..The evidence is critically discussed and directions for future investigations are suggested...