Neil E Torbett

Summary

Affiliation: The Royal Veterinary College

Publications

  1. ncbi A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
    Neil E Torbett
    Cancer Research Institute, University of California, San Francisco, CA 94143, USA
    Biochem J 415:97-110. 2008
  2. ncbi Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1
    Neil E Torbett
    Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    J Biol Chem 278:32344-51. 2003

Collaborators

Detail Information

Publications2

  1. ncbi A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
    Neil E Torbett
    Cancer Research Institute, University of California, San Francisco, CA 94143, USA
    Biochem J 415:97-110. 2008
    ..Taken together, our data indicate that these compounds, alone or in suitable combinations, may be useful as breast cancer therapeutics, when used in appropriate genetic contexts...
  2. ncbi Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1
    Neil E Torbett
    Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    J Biol Chem 278:32344-51. 2003
    ..Taken together, our findings present a pathway for the selective hyperosmotic-induced Rac1-dependent PKN1 translocation and PDK1-dependent activation...