Neil E Torbett

Summary

Affiliation: The Royal Veterinary College

Publications

  1. pmc A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
    Neil E Torbett
    Cancer Research Institute, University of California, San Francisco, CA 94143, USA
    Biochem J 415:97-110. 2008
  2. ncbi request reprint Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1
    Neil E Torbett
    Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    J Biol Chem 278:32344-51. 2003

Collaborators

Detail Information

Publications2

  1. pmc A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition
    Neil E Torbett
    Cancer Research Institute, University of California, San Francisco, CA 94143, USA
    Biochem J 415:97-110. 2008
    ..Taken together, our data indicate that these compounds, alone or in suitable combinations, may be useful as breast cancer therapeutics, when used in appropriate genetic contexts...
  2. ncbi request reprint Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1
    Neil E Torbett
    Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    J Biol Chem 278:32344-51. 2003
    ..Taken together, our findings present a pathway for the selective hyperosmotic-induced Rac1-dependent PKN1 translocation and PDK1-dependent activation...