Monique A J Rennen

Summary

Affiliation: TNO Chemistry
Country: The Netherlands

Publications

  1. ncbi request reprint Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment
    Monique A J Rennen
    Department of Toxicological Risk Assessment, TNO Chemistry, P O Box 360, 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 39:5-11. 2004
  2. ncbi request reprint Inhaled formaldehyde: evaluation of sensory irritation in relation to carcinogenicity
    Josje H E Arts
    TNO Quality of Life, Zeist, P O Box 360, 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 44:144-60. 2006
  3. doi request reprint Application of the threshold of toxicological concern (TTC) concept to the safety assessment of chemically complex food matrices
    Monique A J Rennen
    TNO Quality of Life, Zeist, The Netherlands, Utrechtseweg 48, PO Box 360, 3700 AJ Zeist, The Netherlands
    Food Chem Toxicol 49:933-40. 2011
  4. ncbi request reprint Prediction of local irritant effects after repeated dermal and respiratory exposure to chemicals
    Monique A J Rennen
    Department of Toxicological Risk Assessment, TNO Chemistry, P O Box 360, NL 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 36:253-61. 2002
  5. ncbi request reprint Within-animal variation as an indication of the minimal magnitude of the critical effect size for continuous toxicological parameters applicable in the benchmark dose approach
    Susan Dekkers
    Food and Chemical Risk Analysis, TNO Quality of Life, P O Box 360, Utrechtseweg 48, Zeist, 3700 AJ, The Netherlands
    Risk Anal 26:867-80. 2006

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment
    Monique A J Rennen
    Department of Toxicological Risk Assessment, TNO Chemistry, P O Box 360, 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 39:5-11. 2004
    ..Especially, in cases where chemical exposure by inhalation or skin contact cannot be excluded route-specific toxicity studies should be considered to prevent from inadequate estimates of human health risks...
  2. ncbi request reprint Inhaled formaldehyde: evaluation of sensory irritation in relation to carcinogenicity
    Josje H E Arts
    TNO Quality of Life, Zeist, P O Box 360, 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 44:144-60. 2006
    ..In addition, a Benchmark dose (BMD) analysis of sensory irritation was used to estimate response incidences at different formaldehyde concentrations...
  3. doi request reprint Application of the threshold of toxicological concern (TTC) concept to the safety assessment of chemically complex food matrices
    Monique A J Rennen
    TNO Quality of Life, Zeist, The Netherlands, Utrechtseweg 48, PO Box 360, 3700 AJ Zeist, The Netherlands
    Food Chem Toxicol 49:933-40. 2011
    ..This paper describes the criteria and development of the framework proposing a stepwise approach for the application of TTC in safety assessment of CCFM and future developments required...
  4. ncbi request reprint Prediction of local irritant effects after repeated dermal and respiratory exposure to chemicals
    Monique A J Rennen
    Department of Toxicological Risk Assessment, TNO Chemistry, P O Box 360, NL 3700 AJ Zeist, The Netherlands
    Regul Toxicol Pharmacol 36:253-61. 2002
    ..We conclude that the presumed reliability of route-to-route extrapolation in the absence of route-specific toxicity data can be questioned...
  5. ncbi request reprint Within-animal variation as an indication of the minimal magnitude of the critical effect size for continuous toxicological parameters applicable in the benchmark dose approach
    Susan Dekkers
    Food and Chemical Risk Analysis, TNO Quality of Life, P O Box 360, Utrechtseweg 48, Zeist, 3700 AJ, The Netherlands
    Risk Anal 26:867-80. 2006
    ..6% and 34% for different clinical chemistry and hematological parameters in 90-day rat studies. This indicates that different (minimal) CES values may be applicable for different parameters...