Research Topics
| C KrulSummaryAffiliation: TNO Nutrition and Food Research Country: The Netherlands Publications
| Collaborators |
Detail Information
Publications
Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compoundsC Krul
TNO Nutrition and Food Research Institute, Utrechtseweg 48, PO Box 360, 3700, AJ Zeist, The Netherlands
Food Chem Toxicol 38:783-92. 2000..More generally, these studies indicate that TIM shows promise as a useful tool for various research purposes dealing with the availability for absorption of mutagenic as well as antimutagenic components in food...
Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal modelC Krul
TNO Nutrition and Food Research, P O Box 360, 3700, AJ Zeist, The Netherlands
Mutat Res 474:71-85. 2001..catechin, epigallocatechin gallate and epigallocatechin. The in vitro gastrointestinal model appears to be a useful tool to study the antimutagenicity of food components...
Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal modelCyrille Krul
TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
Carcinogenesis 23:1009-16. 2002..Between 10% and 30% (mean 19%) of the sinigrin was converted into allyl isothiocyanate. The results of this study suggest that allyl isothiocyanate is converted further into other, yet unknown, metabolites...
Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditionsCyrille A M Krul
TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
Food Chem Toxicol 42:51-63. 2004..that the results obtained with this model are helpful in evaluating human cancer risk for the combined intake of codfish-like fish species and nitrate-containing vegetables...
