C Krul

Summary

Affiliation: TNO Nutrition and Food Research
Country: The Netherlands

Publications

  1. ncbi request reprint Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds
    C Krul
    TNO Nutrition and Food Research Institute, Utrechtseweg 48, PO Box 360, 3700, AJ Zeist, The Netherlands
    Food Chem Toxicol 38:783-92. 2000
  2. ncbi request reprint Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model
    C Krul
    TNO Nutrition and Food Research, P O Box 360, 3700, AJ Zeist, The Netherlands
    Mutat Res 474:71-85. 2001
  3. ncbi request reprint Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model
    Cyrille Krul
    TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
    Carcinogenesis 23:1009-16. 2002
  4. ncbi request reprint Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions
    Cyrille A M Krul
    TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
    Food Chem Toxicol 42:51-63. 2004

Detail Information

Publications4

  1. ncbi request reprint Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds
    C Krul
    TNO Nutrition and Food Research Institute, Utrechtseweg 48, PO Box 360, 3700, AJ Zeist, The Netherlands
    Food Chem Toxicol 38:783-92. 2000
    ..More generally, these studies indicate that TIM shows promise as a useful tool for various research purposes dealing with the availability for absorption of mutagenic as well as antimutagenic components in food...
  2. ncbi request reprint Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model
    C Krul
    TNO Nutrition and Food Research, P O Box 360, 3700, AJ Zeist, The Netherlands
    Mutat Res 474:71-85. 2001
    ..catechin, epigallocatechin gallate and epigallocatechin. The in vitro gastrointestinal model appears to be a useful tool to study the antimutagenicity of food components...
  3. ncbi request reprint Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model
    Cyrille Krul
    TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
    Carcinogenesis 23:1009-16. 2002
    ..Between 10% and 30% (mean 19%) of the sinigrin was converted into allyl isothiocyanate. The results of this study suggest that allyl isothiocyanate is converted further into other, yet unknown, metabolites...
  4. ncbi request reprint Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions
    Cyrille A M Krul
    TNO Nutrition and Food Research, PO Box 360, 3700 AJ Zeist, The Netherlands
    Food Chem Toxicol 42:51-63. 2004
    ..that the results obtained with this model are helpful in evaluating human cancer risk for the combined intake of codfish-like fish species and nitrate-containing vegetables...