Research Topics
| M D WaldingerSummaryAffiliation: The Hague Country: The Netherlands Publications
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Detail Information
Publications
Treatment of hot flushes with mirtazapine: four case reportsM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, Leyweg 275, 2545 CH, The Hague, The Netherlands
Maturitas 36:165-8. 2000..On the basis of this observation clinical studies were extended with two non-depressed and non-anxious women with hot flushes. Both subjects were prescribed mirtazapine daily...
Lifelong premature ejaculation: from authority-based to evidence-based medicineM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
BJU Int 93:201-7. 2004..Moreover, animal studies show the presence of a distinct ejaculation-related neural circuit in the central nervous system; its role in premature ejaculation remains to be elucidated...
Towards evidence-based drug treatment research on premature ejaculation: a critical evaluation of methodologyM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
Int J Impot Res 15:309-13. 2003....
Antidepressants and ejaculation: a double-blind, randomized, fixed-dose study with mirtazapine and paroxetineMarcel D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
J Clin Psychopharmacol 23:467-70. 2003..9-fold increase). These results confirm earlier findings that paroxetine, but not mirtazapine, significantly delays orgasm and ejaculation in men with early ejaculation, whereas mirtazapine is devoid of any effect on it...
Postorgasmic illness syndrome: two casesMarcel D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, Leyweg 275, 2545 CH The Hague, The Netherlands
J Sex Marital Ther 28:251-5. 2002..Both cases are presented to draw attention to this syndrome for further research regarding etiology, pathogenesis, and treatment...
SSRIs and ejaculation: a double-blind, randomized, fixed-dose study with paroxetine and citalopramM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
J Clin Psychopharmacol 21:556-60. 2001..8-fold increase). These results indicate that paroxetine leads to a significant delay in orgasm and ejaculation, whereas citalopram seems to have less of an effect on it...
Antidepressants and ejaculation: a double-blind, randomized, placebo-controlled, fixed-dose study with paroxetine, sertraline, and nefazodoneM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
J Clin Psychopharmacol 21:293-7. 2001..85). Compared with baseline, paroxetine exerted the strongest delay in ejaculation, whereas sertraline delayed it only moderately. There was no clinically relevant delay in ejaculation with nefazodone...
Relevance of methodological design for the interpretation of efficacy of drug treatment of premature ejaculation: a systematic review and meta-analysisM D Waldinger
Department of Psychiatry and Neurosexology, Leyenburg Hospital, The Hague, The Netherlands
Int J Impot Res 16:369-81. 2004..Single-blind studies, open designs, retrospective reporting, or the use of a questionnaire to assess ejaculation time should be avoided...
Animal models of ejaculatory behaviorT Pattij
Department of Psychiatry and Neurosexology, Leyenburg Hospital, Leyweg 275, 2545 CH The Hague, The Netherlands
Curr Pharm Des 11:4069-77. 2005..Together, these preclinical studies may contribute to a better understanding of the neurobiology of ejaculation and help the development of novel drug targets to treat ejaculatory disorders such as premature ejaculation...
Effects of chronic paroxetine pretreatment on (+/-)-8-hydroxy-2-(di-n-propyl-amino)tetralin induced c-fos expression following sexual behaviorT R de Jong
Department of Anatomy, Radboud University Nijmegen Medical Centre, The Netherlands
Neuroscience 134:1351-61. 2005....
Psychopharmacology of male rat sexual behavior: modeling human sexual dysfunctions?B Olivier
Department of Psychopharmacology, Utrecht Institute for Pharmaceutical Sciences and Rudolf Magnus Institute of Neuroscience, Utrecht University, Utrecht, The Netherlands
Int J Impot Res 18:S14-23. 2006..These preclinical studies and models contribute to a better understanding of the neurobiology of ejaculation and boost the development of novel drug targets to treat ejaculatory disorders such as premature and retarded ejaculation...
