Neil K Aaronson

..This study investigated adherence to treatment guidelines on cancer-related anaemia and fatigue (CRA/CRF) and factors influencing the choice of intervention...

..These new CAT measures are conceptualised to reflect the same constructs as the QLQ-C30 scales. Accordingly, the Fatigue-CAT is intended to capture physical and general fatigue...

..This article reviews issues that arise when testing for DIF in HRQoL instruments. We focus on logistic regression methods, which are often used because of their efficiency, simplicity and ease of application...

..This study aimed to determine the relative and absolute reliability of intra and inter-observer strength measurements with a hand-held dynamometer (HHD)...

..A systematic review was performed to summarize the current evidence of the effect of physical activity interventions on daily walking activity enhancement in cancer survivors, and to review the literature for its methodological quality...

..A second aim is to link information on quality of life to clinical pathways and treatment guidelines...

..To investigate the generic and condition-specific health-related quality of life (HRQL) of patients with low-grade glioma (LGG)...

..The aim of the current study was to identify baseline predictors of PBSO versus gynecologic screening (GS) in this group of high-risk women...

..Physicians need to provide younger high-risk women considering PBSO with realistic information about both benefits and drawbacks of this preventive strategy, including information about premature menopause and HRT...

..These results, obtained in a homogenous group of patients, may serve as HRQOL benchmarks for future studies investigating surgical and other treatment modalities...

..Routine discussion of all reproductive options with a medical specialist should be encouraged...

..Our aim was to assess levels and predictors of psychological distress and quality of life (QOL) among partners of FAP-patients...

..Little is known about the psychological impact and treatment consequences of rapid genetic counseling and testing offered between breast cancer diagnosis and surgery...

..To evaluate the effect of behavioral techniques and physical exercise on psychosocial functioning and health-related quality of life (HRQoL) outcomes in breast cancer patients and survivors...

..We concluded that baseline HRQOL is not related to duration of survival and that long-term survivors show improvement of HRQOL to a level comparable to that of the healthy...

..It can be used in future comparative studies for oral and oropharyngeal cancer and in clinical practice to identify patients in need of further diagnostics and/or swallowing rehabilitation services...

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..1) To translate and validate the COOP/WONCA charts in Turkish, Moroccan-Arabic, and Tarifit for use among ethnic minority cancer patients in the Netherlands, and (2) to determine the patient-proxy agreement for Dutch speaking proxies...

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..A Speech Handicap Index (SHI) questionnaire with 30 items on speech problems was developed and validated in 92 patients with cancer of the oral cavity or pharynx and 110 healthy subjects...

..Practical approaches to resolving these issues are presented...

..However, many previous studies had methodological weaknesses related to trial design, sample size, comparison group, outcome measures, short follow-up durations and programme content...

..quot; The purpose of this study was to evaluate these to proxy perspectives in terms of patient-proxy bias and agreement...

..To evaluate the psychometrics of the SF-36 Health Survey among Turkish and Moroccan ethnic minority populations in the Netherlands and to compare the results to those based on the indigenous Dutch population...

..To evaluate long-term changes in health related quality of life (HRQOL) in oral/oropharyngeal cancer survivors and their need for and use of supportive care...

..The aim of this study is to determine the effect of RGCT on treatment decisions and on psychosocial health...

..This nationwide study assessed: (1) the prevalence of psychological distress; and (2) the need for and use of specialized professional psychosocial support...

..In this study, we evaluated the uptake of genetic testing and the psychosocial impact of undergoing or not undergoing a genetic test for LFS...

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..The aim of this study was to assess a range of health-related quality of life outcomes in patients with esophageal cancer treated with potentially curative intent at least 1 year earlier...

..The objective of this study is to investigate the efficacy of these interventions among women with breast cancer experiencing treatment-induced menopause...

..Additional studies are needed to confirm the psychometrics of the questionnaire when used among these ethnic minority groups in other Western European countries...

..As stereotactic ablative radiotherapy (SABR) can result in local control percentages exceeding 90%, we studied baseline and post-treatment HRQOL in SABR patients...

..In conclusion, low-grade glioma patients suffer from a number of neuropsychological and psychological problems that are aggravated by the severity of epilepsy and by the intensity of the treatment...

..By taking the preferences of patients into account, trust in medical practice can be maintained...

..To investigate the statistical fit of alternative higher order models for summarizing the health-related quality of life profile generated by the EORTC QLQ-C30 questionnaire...

..The present randomized trial investigated the measurement properties of the EORTC QLQ-C30 under three different modes of administration (MOA's)...

..To obtain consent from breast cancer survivors to use residual tissue for a study on carriership of germ line mutations in the BRCA 1 and 2 genes. To investigate which consent regimen patients prefer for research with archived tissue...

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..CONCLUSION: On average, four years after genetic counselling for HNPCC, only a small minority of counselled individuals reports clinically significant levels of distress, or significant family or social problems...

..The aims of this study were to determine the degree of compliance and to identify the factors related significantly to noncompliance with periodic screening in this high-risk population...

..Balanced information will help clinicians and high-risk women to make informed decisions about the optimal preventive health strategy...

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..To assess compliance with a periodic surveillance regimen for Von Hippel-Lindau disease...

..Knowledge of pretreatment HRQOL and functional status levels is useful for better understanding the impact of treatment on these outcomes over time...

..CONCLUSION: Incorporating standardized HRQL assessments in daily clinical oncology practice facilitates the discussion of HRQL issues and can heighten physicians' awareness of their patients' HRQL...

..Chromogranin A (CgA) is a promising marker, but a thorough evaluation during follow-up is still lacking...

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..In addition, the possible impact of genetic testing on insurance, work and future plans is discussed. Suggestions are given for translating research findings into psychosocial services and future research efforts...