Elke E M Brouwers
Affiliation: Slotervaart Hospital
Country: The Netherlands
Brouwers E, Huitema A, Beijnen J, Schellens J. Long-term platinum retention after treatment with cisplatin and oxaliplatin. BMC Clin Pharmacol. 2008;8:7 pubmed publisher
..Platinum species in pUF were partly present in a reactive form. The effects of the reactivity on long-term consequences of Pt-containing chemotherapy, however, remains to be established. ..
Brouwers E, Sohne M, Kuipers S, van Gorp E, Schellens J, Koks C, et al
. Ciprofloxacin strongly inhibits clozapine metabolism: two case reports. Clin Drug Investig. 2009;29:59-63 pubmed publisher
..This might cause severe adverse effects. We advise using another antibacterial agent or reducing the clozapine dose and monitoring clozapine levels when this antipsychotic agent is used in combination with ciprofloxacin. ..
Brouwers E, Huitema A, Boogerd W, Beijnen J, Schellens J. Persistent neuropathy after treatment with cisplatin and oxaliplatin. Acta Oncol. 2009;48:832-41 pubmed publisher
..This study was performed as an explorative study and the issues discussed need to be investigated further. ..