Manuel Castro Cabezas

Summary

Affiliation: Sint Franciscus Gasthuis
Country: The Netherlands

Publications

  1. ncbi Effects of atorvastatin on the clearance of triglyceride-rich lipoproteins in familial combined hyperlipidemia
    M Castro Cabezas
    Department of Internal Medicine, St Franciscus Gasthuis Rotterdam, 3004 BA Rotterdam, The Netherlands
    J Clin Endocrinol Metab 89:5972-80. 2004
  2. doi Leukocyte activation by triglyceride-rich lipoproteins
    Arash Alipour
    Department of Internal Medicine, University Medical Center Utrecht, The Netherlands
    Arterioscler Thromb Vasc Biol 28:792-7. 2008
  3. pmc Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution
    Jeroen P H van Wijk
    Department of Internal Medicine, University Medical Center, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Int J Vasc Med 2012:201027. 2012
  4. pmc Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases
    Boudewijn Klop
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis, 3004 BA Rotterdam, The Netherlands
    Int J Vasc Med 2012:947417. 2012
  5. pmc AT1 Receptor Gene Polymorphisms in relation to Postprandial Lipemia
    B Klop
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St Franciscus Gasthuis, P O Box 10900, 3004 BA Rotterdam, The Netherlands
    Int J Vasc Med 2012:271030. 2012
  6. pmc Effects of metformin on the regulation of free Fatty acids in insulin resistance: a double-blind, placebo-controlled study
    Manuel Castro Cabezas
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis Rotterdam, P O Box 10900, 3004 BA Rotterdam, The Netherlands
    J Nutr Metab 2012:394623. 2012
  7. pmc Diurnal triglyceridemia in relation to alcohol intake in men
    Ana Torres do Rego
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St Franciscus Gasthuis, P O Box 10900, Rotterdam 3004 BA, The Netherlands
    Nutrients 5:5114-26. 2013
  8. pmc Dyslipidemia in obesity: mechanisms and potential targets
    Boudewijn Klop
    Department of Internal Medicine, Diabetes and Vascular Centre, Sint Franciscus Gasthuis, Rotterdam, P O Box 10900, 3004 BA, The Netherlands
    Nutrients 5:1218-40. 2013
  9. ncbi A physician's guide for the management of hypertriglyceridemia: the etiology of hypertriglyceridemia determines treatment strategy
    B Klop
    Department of Internal Medicine, Diabetes and Vascular Center, Sint Franciscus Gasthuis Rotterdam, The Netherlands
    Panminerva Med 54:91-103. 2012
  10. ncbi Effects of a stanol-enriched diet on plasma cholesterol and triglycerides in patients treated with statins
    Manuel Castro Cabezas
    St Franciscus Gasthuis Rotterdam, Department of Internal Medicine, University Medical Center Utrecht, The Netherlands
    J Am Diet Assoc 106:1564-9. 2006

Collaborators

Detail Information

Publications28

  1. ncbi Effects of atorvastatin on the clearance of triglyceride-rich lipoproteins in familial combined hyperlipidemia
    M Castro Cabezas
    Department of Internal Medicine, St Franciscus Gasthuis Rotterdam, 3004 BA Rotterdam, The Netherlands
    J Clin Endocrinol Metab 89:5972-80. 2004
    ..Fasting plasma TG should be reduced more aggressively in FCHL to overcome the lipolytic disturbance causing delayed clearance of postprandial TRLs...
  2. doi Leukocyte activation by triglyceride-rich lipoproteins
    Arash Alipour
    Department of Internal Medicine, University Medical Center Utrecht, The Netherlands
    Arterioscler Thromb Vasc Biol 28:792-7. 2008
    ..Postprandial lipemia has been linked to atherosclerosis and inflammation. Because leukocyte activation is obligatory for atherogenesis, leukocyte activation by triglyceride-rich lipoproteins (TRLs) was investigated...
  3. pmc Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution
    Jeroen P H van Wijk
    Department of Internal Medicine, University Medical Center, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Int J Vasc Med 2012:201027. 2012
    ..This paper reviews the contribution of both, HIV infection and CART, to insulin resistance, postprandial hyperlipidemia and cardiovascular risk in HIV-infected patients. Strategies to reduce cardiovascular risk are also discussed...
  4. pmc Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases
    Boudewijn Klop
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis, 3004 BA Rotterdam, The Netherlands
    Int J Vasc Med 2012:947417. 2012
    ..This paper will provide an update on current concepts concerning the relationship between postprandial lipemia, inflammation, vascular function, and therapeutic options...
  5. pmc AT1 Receptor Gene Polymorphisms in relation to Postprandial Lipemia
    B Klop
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St Franciscus Gasthuis, P O Box 10900, 3004 BA Rotterdam, The Netherlands
    Int J Vasc Med 2012:271030. 2012
    ..Conclusion. The 1166-C allele of the AT1R gene seems to be associated with increased postprandial lipemia. These data confirm the earlier described relationships between the renin-angiotensin axis and triglyceride metabolism...
  6. pmc Effects of metformin on the regulation of free Fatty acids in insulin resistance: a double-blind, placebo-controlled study
    Manuel Castro Cabezas
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis Rotterdam, P O Box 10900, 3004 BA Rotterdam, The Netherlands
    J Nutr Metab 2012:394623. 2012
    ..Metformin most likely decreases plasma FFAs mainly by suppressing fasting FFA concentrations and not by suppression of acute stress-induced lipolysis...
  7. pmc Diurnal triglyceridemia in relation to alcohol intake in men
    Ana Torres do Rego
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St Franciscus Gasthuis, P O Box 10900, Rotterdam 3004 BA, The Netherlands
    Nutrients 5:5114-26. 2013
    ..05). In males, low alcohol intake was associated with decreased diurnal triglyceridemia, whereas moderate and high alcohol intake was associated with increased triglycerides after dinner and at bed time. ..
  8. pmc Dyslipidemia in obesity: mechanisms and potential targets
    Boudewijn Klop
    Department of Internal Medicine, Diabetes and Vascular Centre, Sint Franciscus Gasthuis, Rotterdam, P O Box 10900, 3004 BA, The Netherlands
    Nutrients 5:1218-40. 2013
    ..The current review will focus on these aspects of lipid metabolism in obesity and potential interventions to treat the obesity related dyslipidemia...
  9. ncbi A physician's guide for the management of hypertriglyceridemia: the etiology of hypertriglyceridemia determines treatment strategy
    B Klop
    Department of Internal Medicine, Diabetes and Vascular Center, Sint Franciscus Gasthuis Rotterdam, The Netherlands
    Panminerva Med 54:91-103. 2012
    ..Finally, family screening is mandatory to detect familial lipid disorders for early intervention in other family members...
  10. ncbi Effects of a stanol-enriched diet on plasma cholesterol and triglycerides in patients treated with statins
    Manuel Castro Cabezas
    St Franciscus Gasthuis Rotterdam, Department of Internal Medicine, University Medical Center Utrecht, The Netherlands
    J Am Diet Assoc 106:1564-9. 2006
    ..It is unclear whether plant stanols in combination with dietary guidance in patients already using optimal doses of statins will further reduce fasting and postprandial lipids compared with standard care...
  11. pmc Erythrocyte-bound apolipoprotein B in relation to atherosclerosis, serum lipids and ABO blood group
    Boudewijn Klop
    Department of Internal Medicine, Diabetes and Vascular Center, Sint Franciscus Gasthuis, Rotterdam, The Netherlands
    PLoS ONE 8:e75573. 2013
    ..We aimed to explore the determinants of ery-apoB to gain more insight into potential mechanisms...
  12. doi Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy
    Jeroen P H van Wijk
    Department of Internal Medicine, St Franciscus Gasthuis Rotterdam, 3004 BA Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 31:228-33. 2011
    ..To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy...
  13. doi Glucose-dependent leukocyte activation in patients with type 2 diabetes mellitus, familial combined hyperlipidemia and healthy controls
    Marijke A de Vries
    Department of Internal Medicine, Center for Diabetes and Cardiovascular Risk Management, Sint Franciscus Gasthuis, Rotterdam, The Netherlands Electronic address
    Metabolism 64:213-7. 2015
    ..Hyperglycemia may be involved in this leukocyte activation. Our aim was to investigate the role of elevated glucose concentrations on leukocyte activation in patients with a wide range of insulin sensitivity...
  14. doi Coronary leukocyte activation in relation to progression of coronary artery disease
    Marijke A de Vries
    Department of Internal Medicine, Centre for Diabetes and Vascular Medicine, Sint Franciscus Gasthuis, Rotterdam, P O Box 10900, 3004 BA, The Netherlands
    Front Med 10:85-90. 2016
    ..These data indicate that coronary monocyte CD11b, neutrophil CD11b and CD66b expression and intracellular MPO do not predict the risk of progression of CAD. ..
  15. doi Alcohol and plasma triglycerides
    Boudewijn Klop
    Department of Internal Medicine, Sint Franciscus Gasthuis Rotterdam, The Netherlands
    Curr Opin Lipidol 24:321-6. 2013
    ..This study reviews recent developments concerning the effects of alcohol on plasma triglycerides. The focus will be on population, intervention and metabolic studies with respect to alcohol and plasma triglycerides...
  16. pmc Systemic inflammation and lung function impairment in morbidly obese subjects with the metabolic syndrome
    Astrid van Huisstede
    Department of Pulmonology, Sint Franciscus Gasthuis, Kleiweg 500, 3045 PM Rotterdam, The Netherlands
    J Obes 2013:131349. 2013
    ..Hypothesis. Low-grade systemic inflammation associated with the metabolic syndrome causes inflammation in the lungs and, hence, lung function impairment...
  17. ncbi [Cholesterol homeostasis and enterohepatic connection: new insights in cholesterol absorption]
    Boudewijn Klop
    Sint Franciscus Gasthuis, afd Interne Geneeskunde, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 155:A2503. 2011
    ..When the effect of statins is insufficient or they cause too many side-effects, additional inhibition of intestinal cholesterol absorption is indicated...
  18. doi Exploring the value of apoB48 as a marker for atherosclerosis in clinical practice
    Arash Alipour
    Department of Internal Medicine, Center for Diabetes and Vascular Medicine, St Franciscus Gasthuis, Rotterdam, The Netherlands
    Eur J Clin Invest 42:702-8. 2012
    ..Scarce data are available on fasting plasma apolipoprotein (apo) B48 levels in relation to these conditions and atherosclerosis...
  19. doi MTP gene polymorphisms and postprandial lipemia in familial combined hyperlipidemia: effects of treatment with atorvastatin
    Boudewijn Klop
    Department of Internal Medicine, Sint Franciscus Gasthuis, Rotterdam, The Netherlands
    Clin Investig Arterioscler 26:49-57. 2014
    ..We studied the effect of the functional MTP-493G/T polymorphism on fasting and postprandial lipoproteins in patients with familial combined hyperlipidemia (FCH) before and after treatment with atorvastatin...
  20. doi Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin
    Arash Alipour
    Department of Internal Medicine, St Franciscus Gasthuis Rotterdam, The Netherlands
    Atherosclerosis 215:125-9. 2011
    ..We evaluated whether the rate of angiographic progression of coronary atherosclerosis during pravastatin treatment was associated with MBL2 haplotypes in REGRESS, a placebo-controlled 2 years intervention study...
  21. ncbi Rosiglitazone modulates fasting and post-prandial paraoxonase 1 activity in type 2 diabetic patients
    Jeroen van Wijk
    Department of Internal Medicine, University Medical Center, Utrecht, The Netherlands
    Clin Exp Pharmacol Physiol 33:1134-7. 2006
    ..59; P < 0.01) and peroxides (r = -0.40; P = 0.07). 4. The present data indicate that rosiglitazone may convey increased protection against the oxidative modification that represents increased post-prandial lipaemia...
  22. ncbi Normal ranges of non-fasting triglycerides in healthy Dutch males and females
    Jeroen P H van Wijk
    Department of Vascular Medicine G02 405, University Medical Center, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Clin Chim Acta 337:49-57. 2003
    ..Increased triglycerides (TG) are associated with atherosclerosis. We determined free-living non-fasting TG concentrations in healthy Dutch subjects...
  23. ncbi Addition of glucose to an oral fat load reduces postprandial free fatty acids and prevents the postprandial increase in complement component 3
    Antonie J van Oostrom
    Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, Netherlands
    Am J Clin Nutr 79:510-5. 2004
    ..C3 is the central component of the complement system and the precursor of acylation-stimulating protein (ASP). Insulin and ASP are principal determinants of free fatty acid (FFA) trapping by adipose tissue...
  24. ncbi Rosiglitazone improves postprandial triglyceride and free fatty acid metabolism in type 2 diabetes
    Jeroen P H van Wijk
    Department of Internal Medicine, University Medical Center Utrecht, Room G02 402, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Diabetes Care 28:844-9. 2005
    ..We investigated the effects of the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone on postprandial lipemia in patients with type 2 diabetes...
  25. ncbi Lower birth weight predicts metabolic syndrome in young adults: the Atherosclerosis Risk in Young Adults (ARYA)-study
    Made K Ramadhani
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Atherosclerosis 184:21-7. 2006
    ..To study the relationship between intrauterine growth and the metabolic syndrome, particularly fasting serum lipids in young adulthood...
  26. ncbi Effects of rosiglitazone and metformin on postprandial paraoxonase-1 and monocyte chemoattractant protein-1 in human immunodeficiency virus-infected patients with lipodystrophy
    Blai Coll
    Servei de Medicina Interna and Centre de Recerca Biomèdica, Hospital Universitari, de Sant Joan, Reus, Spain
    Eur J Pharmacol 544:104-10. 2006
    ..To decrease insulin resistance results in a higher anti-oxidant and consequent lower pro-inflammatory action of HDL. This may confer protection against accelerated atherosclerosis in these patients...
  27. ncbi Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia
    Josep Ribalta
    Unitat de Recerca de Lipids i Arteriosclerosi, Institut de Recerca en Ciències de la Salut, Hospital Universitari de Sant Joan, Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Spain
    Clin Chem 48:1597-600. 2002