Peter A G M De Smet

Summary

Affiliation: Scientific Institute Dutch Pharmacists
Country: The Netherlands

Publications

  1. ncbi request reprint Introduction to the pharmacoeconomics of herbal medicines
    P A de Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Pharmacoeconomics 18:1-7. 2000
  2. ncbi request reprint Clinical risk management in Dutch community pharmacies: the case of drug-drug interactions
    Henk Buurma
    SIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands
    Drug Saf 29:723-32. 2006
  3. ncbi request reprint Possible drug-metabolism interactions of medicinal herbs with antiretroviral agents
    Carolien J P van den Bout-van den Beukel
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Drug Metab Rev 38:477-514. 2006
  4. ncbi request reprint Therapeutic drug monitoring of antidepressants and cytochrome p450 genotyping in general practice
    Jenny E Kootstra-Ros
    Department of Clinical Chemistry, St Jansdal Hospital, 3840 AC Harderwijk, The Netherlands
    J Clin Pharmacol 46:1320-7. 2006
  5. pmc Clinical risk management of herb-drug interactions
    Peter A G M De Smet
    Scientific Institute of Dutch Pharmacists, The Hague and Department of Clinical Pharmacy, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Br J Clin Pharmacol 63:258-67. 2007
  6. ncbi request reprint A composite screening tool for medication reviews of outpatients: general issues with specific examples
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Drugs Aging 24:733-60. 2007
  7. ncbi request reprint Health risks of herbal remedies: an update
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Clin Pharmacol Ther 76:1-17. 2004
  8. ncbi request reprint Clinical risk management of interactions between natural products and drugs
    Peter A G M De Smet
    Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Curr Drug Metab 9:1055-62. 2008
  9. ncbi request reprint Can drug regimens be adapted to patients, or vice versa?
    Peter A G M De Smet
    Department of Clinical Pharmacy, University Medical Centre St Radboud, 6525GA Nijmegen, Netherlands
    Lancet 370:813-4. 2007
  10. ncbi request reprint The interference of botanicals and nutraceuticals with the effects of antithrombotic agents: how should the available evidence be weighed?
    Peter A G M De Smet
    Scientific Institute of Dutch Pharmacists, Alexanderstraat 11, 2514 JL The Hague, The Netherlands
    Thromb Res 117:19-24; discussion 39-42. 2005

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Introduction to the pharmacoeconomics of herbal medicines
    P A de Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Pharmacoeconomics 18:1-7. 2000
    ..At present, such studies are particularly important for Germany, but in the future they may also become relevant for other countries, inside as well as outside Europe...
  2. ncbi request reprint Clinical risk management in Dutch community pharmacies: the case of drug-drug interactions
    Henk Buurma
    SIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands
    Drug Saf 29:723-32. 2006
    ..The objective of our study was to measure the frequency, nature and management of drug-drug interaction alerts as these occur in daily practice of Dutch community pharmacies...
  3. ncbi request reprint Possible drug-metabolism interactions of medicinal herbs with antiretroviral agents
    Carolien J P van den Bout-van den Beukel
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Drug Metab Rev 38:477-514. 2006
    ..Further pharmacokinetic studies to unveil potential Western and especially African herb-antiretroviral drug interactions are urgently required, and the clinical significance of these interactions should be assessed...
  4. ncbi request reprint Therapeutic drug monitoring of antidepressants and cytochrome p450 genotyping in general practice
    Jenny E Kootstra-Ros
    Department of Clinical Chemistry, St Jansdal Hospital, 3840 AC Harderwijk, The Netherlands
    J Clin Pharmacol 46:1320-7. 2006
    ..These results strongly suggest that the rationale for therapeutic drug monitoring and CYP genotyping when prescribing antidepressants in secondary care also applies to the primary care setting...
  5. pmc Clinical risk management of herb-drug interactions
    Peter A G M De Smet
    Scientific Institute of Dutch Pharmacists, The Hague and Department of Clinical Pharmacy, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Br J Clin Pharmacol 63:258-67. 2007
    ..This paper reviews which steps should be explored or taken in these domains to improve the clinical risk management of adverse herb-drug interactions...
  6. ncbi request reprint A composite screening tool for medication reviews of outpatients: general issues with specific examples
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Drugs Aging 24:733-60. 2007
    ..A broad selection of specific examples and references that can be used as a basis for explicit screening of medication patterns in outpatients is also offered...
  7. ncbi request reprint Health risks of herbal remedies: an update
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    Clin Pharmacol Ther 76:1-17. 2004
  8. ncbi request reprint Clinical risk management of interactions between natural products and drugs
    Peter A G M De Smet
    Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Curr Drug Metab 9:1055-62. 2008
    ..It argues that specific components of clinical risk management need to be evaluated, before adoption, and then actively implemented if proven valuable...
  9. ncbi request reprint Can drug regimens be adapted to patients, or vice versa?
    Peter A G M De Smet
    Department of Clinical Pharmacy, University Medical Centre St Radboud, 6525GA Nijmegen, Netherlands
    Lancet 370:813-4. 2007
  10. ncbi request reprint The interference of botanicals and nutraceuticals with the effects of antithrombotic agents: how should the available evidence be weighed?
    Peter A G M De Smet
    Scientific Institute of Dutch Pharmacists, Alexanderstraat 11, 2514 JL The Hague, The Netherlands
    Thromb Res 117:19-24; discussion 39-42. 2005
  11. ncbi request reprint [Class substitution as an instrument of efficiency in the supply of medicines: possibilities and limitations]
    P A G M De Smet
    Wetenschappelijk Instituut Nederlandse Apothekers, Postbus 30 460, 2500 GL s Gravenhage
    Ned Tijdschr Geneeskd 146:553-7. 2002
    ..In addition, specific studies are needed to establish whether undesirable effects occur at the patient level...
  12. ncbi request reprint Herbal remedies
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The Netherlands
    N Engl J Med 347:2046-56. 2002
  13. doi request reprint Implementation of a pharmacist-led intervention to enhance statin prescribing for secondary prevention in primary care: a cluster randomized trial
    Caroline H P A van de Steeg-van Gompel
    Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Prev Cardiol 19:169-76. 2012
    ..Research into the effective and efficient implementation of current guidelines on secondary prevention is therefore needed...
  14. doi request reprint The usefulness of antiplatelet prescriptions for the identification of patients with atherothrombosis in primary care: a Dutch cross-sectional study
    Caroline H P A van de Steeg-van Gompel
    Scientific Institute for Quality of Healthcare IQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Eval Clin Pract 18:866-71. 2012
    ..We aimed to assess which method serves best to identify all patients with ACD in Dutch primary care: morbidity records, antiplatelet prescribing records or a combination of these...
  15. pmc Implementation of patient education at first and second dispensing of statins in Dutch community pharmacies: the sequel of a cluster randomized trial
    Caroline H P A van de Steeg-van Gompel
    Scientific Institute for Quality of Healthcare IQ Healthcare, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    BMC Health Serv Res 11:313. 2011
    ....
  16. pmc A nationwide medication incidents reporting system in The Netherlands
    Ka Chun Cheung
    IQ Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Am Med Inform Assoc 18:799-804. 2011
    ..This article describes the architecture, implementation and current status of the CMR in The Netherlands and compare it with similar systems in other countries...
  17. doi request reprint Implementation of a discontinuation letter to reduce long-term benzodiazepine use--a cluster randomized trial
    Caroline H P A van de Steeg-van Gompel
    Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Drug Alcohol Depend 99:105-14. 2009
    ..An informative discontinuation letter for patients has been shown to reduce long-term benzodiazepine use in general practice. However, little is known about its wide scale implementation in primary care...
  18. doi request reprint Comparison of two methods for performing treatment reviews by pharmacists and general practitioners for home-dwelling elderly people
    Wilma Denneboom
    Centre for Quality of Care Research, UMC St Radboud, Nijmegen, The Netherlands
    J Eval Clin Pract 14:446-52. 2008
    ....
  19. pmc Medication errors: the importance of safe dispensing
    Ka Chun Cheung
    Scientific Institute of Dutch Pharmacists, The Hague, The Netherlands
    Br J Clin Pharmacol 67:676-80. 2009
    ....
  20. doi request reprint Classification of medication incidents associated with information technology
    Ka Chun Cheung
    Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Am Med Inform Assoc 21:e63-70. 2014
    ..This study analyzed the nature and consequences of a large sample of IT-related medication incidents, as reported by healthcare professionals in community pharmacies and hospitals...
  21. doi request reprint Self-reported uptake of recommendations after dissemination of medication incident alerts
    Ka Chun Cheung
    IQ Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    BMJ Qual Saf 21:1009-18. 2012
    ..It is up to the healthcare workers whether or not to implement the recommendations in clinical practice, which may lead to variations in degrees of uptake of the recommendations...
  22. doi request reprint Targeting outpatient drug safety: recommendations of the Dutch HARM-Wrestling Task Force
    Margaretha F Warlé-van Herwaarden
    IQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Drug Saf 35:245-59. 2012
    ..These studies prompted the initiation of a Dutch multidisciplinary task force, which was assigned to reduce the number of prescriber-related hospital admissions related to medications (HARMs) in a quick-win way...
  23. ncbi request reprint Herbal medicine in Europe--relaxing regulatory standards
    Peter A G M De Smet
    Scientific Institute of Dutch Pharmacists, The Hague, Netherlands
    N Engl J Med 352:1176-8. 2005
  24. doi request reprint Implementation of adherence support for patients with hypertension despite antihypertensive therapy in general practice: a cluster randomized trial
    Caroline H P A van de Steeg-van Gompel
    IQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Hypertens 23:1038-45. 2010
    ..The aim of the study was to compare the effectiveness of intensive support for implementation of this tool in community pharmacies with minimal implementation support...
  25. pmc How useful are prescribing indicators based on the DU90% method to distinguish the quality of prescribing between pharmacotherapy audit meetings with different levels of functioning?
    Martina Teichert
    Scientific Institute Dutch Pharmacists, Alexanderstraat 11, 2514 JL The Hague, The Netherlands
    Eur J Clin Pharmacol 63:1171-7. 2007
    ..The objective of the study was to assess the association between the quality of drug prescribing based on three indicator types derived from the DU90% method and different levels of functioning in pharmacotherapy audit meetings (PTAMs)...
  26. pmc Treatment reviews of older people on polypharmacy in primary care: cluster controlled trial comparing two approaches
    Wilma Denneboom
    Centre for Quality of Care Research, UMC St Radboud, Nijmegen, The Netherlands
    Br J Gen Pract 57:723-31. 2007
    ..Older people are prone to problems related to use of medicines. As they tend to use many different medicines, monitoring pharmacotherapy for older people in primary care is important...
  27. doi request reprint Erroneous exchange of asparaginase forms in the treatment of acute lymphoblastic leukemia
    Ka Chun Cheung
    IQ Scientific Institute for Quality of Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Pediatr Hematol Oncol 33:e109-13. 2011
    ..This case report describes the actual course of treatment, the reasons why it went wrong, and possible preventive measures...
  28. ncbi request reprint Repeat prescribing: scale, problems and quality management in ambulatory care patients
    Peter A G M De Smet
    Scientific Institute Dutch Pharmacists, The Hague, The NetherlandsDepartment of Clinical Pharmacy, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Drugs 64:1779-800. 2004
    ..Future studies should also assess whether results are sustained, the optimal time interval between reviews of repeat prescriptions, and the possibilities offered by new computerised support technologies...
  29. ncbi request reprint Interventions to improve medication compliance in older patients living in the community: a systematic review of the literature
    Monique van Eijken
    Centre for Quality of Care Research, University Medical Centre Nijmegen, Nijmegen, The Netherlands
    Drugs Aging 20:229-40. 2003
    ....
  30. doi request reprint Adherence to biochemical monitoring recommendations in patients starting with renin angiotensin system inhibitors: a retrospective cohort study in the Netherlands
    Janet E M Bootsma
    Department of Pharmacology Toxicology, Radboud University Nijmegen Medical Centre, The Netherlands
    Drug Saf 34:605-14. 2011
    ..In addition, serum creatinine monitoring was significantly less often performed in high-risk patients compared with low-risk patients...
  31. ncbi request reprint The rationale of scored tablets as dosage form
    Nienke Rodenhuis
    National Institute of Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, P O Box 1, 3720 BA, Bilthoven, The Netherlands
    Eur J Pharm Sci 21:305-8. 2004
    ..Improving the functioning of score lines may be a more practical approach than banning this dosage form...
  32. pmc Evaluation of the clinical value of pharmacists' modifications of prescription errors
    Henk Buurma
    SIR Institute for Pharmacy Practice Research, Leiden, The Netherlands
    Br J Clin Pharmacol 58:503-11. 2004
    ..Our objective was to examine the clinical value of pharmacists' interventions to correct prescription errors...
  33. pmc Analysis of polypharmacy in older patients in primary care using a multidisciplinary expert panel
    Wilma Denneboom
    Centre for Quality of Care Research, UMC St Radboud, 117 KWAZO, 6500 HB Nijmegen, The Netherlands
    Br J Gen Pract 56:504-10. 2006
    ..Therefore, it is important to review pharmacotherapy concerning older patients in primary care in a reliable way...
  34. ncbi request reprint Compliance with national guidelines for the management of drug-drug interactions in Dutch community pharmacies
    Henk Buurma
    SIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands
    Ann Pharmacother 41:2024-31. 2007
    ..Little is known about compliance with pharmacy practice guidelines for the management of drug-drug interaction alerts...
  35. ncbi request reprint Drug dosage adjustments according to renal function at hospital discharge
    Elisabeth A van Dijk
    VieCuri Medical Centre, Venlo, Netherlands
    Ann Pharmacother 40:1254-60. 2006
    ..Adequate dosing of medication in renal impairment to prevent hospitalizations and adverse reactions is a growing concern in the aging society. There are several dosing guidelines available, but structural use is uncommon...
  36. ncbi request reprint Safety concerns about kava not unique
    Peter A G M De Smet
    Lancet 360:1336. 2002
  37. ncbi request reprint Overanticoagulation associated with combined use of antibacterial drugs and acenocoumarol or phenprocoumon anticoagulants
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Thromb Haemost 88:705-10. 2002
    ..Despite the fact that these drugs are frequently prescribed concurrently, there is little quantitative information on the risks of such complications...
  38. ncbi request reprint Recurrent toxic hepatitis in a Caucasian girl related to the use of Shou-Wu-Pian, a Chinese herbal preparation
    Bianca Panis
    Department of Pediatrics, Maasland Hospital, Sittard, The Netherlands
    J Pediatr Gastroenterol Nutr 41:256-8. 2005
  39. ncbi request reprint Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Clin Pharmacol Ther 77:479-85. 2005
    ..We investigated whether NSAIDs were associated with overanticoagulation during therapy with coumarins and evaluated the effect of the CYP2C9 polymorphisms on this potential interaction...
  40. ncbi request reprint Frequency, nature and determinants of pharmaceutical consultations provided in private by Dutch community pharmacists
    Marcel J Kooy
    Apotheek Koning, Amsterdam, The Netherlands
    Pharm World Sci 29:81-9. 2007
    ..This raised the question, how often Dutch community pharmacists have personal consultations with their patients in daily practice, on which factors this depends, and what kind of topics are discussed during these meetings...
  41. pmc Overanticoagulation associated with combined use of lactulose and acenocoumarol or phenprocoumon
    Loes E Visser
    Pharmaco epidemiology Unit, Departments of Internal Medicine and Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Br J Clin Pharmacol 57:522-4. 2004
    ..4, 95% confidence interval 2.2, 5.3). In view of the widespread use of lactulose, especially among the elderly, awareness of this potential drug interaction is required...
  42. ncbi request reprint The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Easmus MC, Rotterdam, The Netherlands
    Pharmacogenetics 14:27-33. 2004
    ..Phenprocoumon appears to be a clinically useful alternative in patients carrying the CYP2C9*2 and *3 alleles...
  43. ncbi request reprint Disease and intolerability documentation in electronic patient records
    Henk Buurma
    SIR Institute for Pharmacy Practice Research, Leiden, Netherlands
    Ann Pharmacother 39:1640-6. 2005
    ..Documentation of diseases and intolerabilities in electronic patient records (EPRs) in pharmacies is needed to produce an alert in case a contraindicated medicine is prescribed. Limited research is available concerning EPRs in pharmacies...