Research Topics
| R E G SchutgensSummaryCountry: The Netherlands Publications
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Publications
Combination of a normal D-dimer concentration and a non-high pretest clinical probability score is a safe strategy to exclude deep venous thrombosisR E G Schutgens
Department of Internal Medicine, St Antonius Hospital, Nieuwegein, The Netherlands
Circulation 107:593-7. 2003..We studied the clinical validity of the combination of a pretest clinical probability score and a D-dimer test in the initial evaluation of patients suspected of deep venous thrombosis...
Low molecular weight heparin (dalteparin) is equally effective as unfractionated heparin in reducing coagulation activity and perfusion abnormalities during the early treatment of pulmonary embolismRoger E G Schutgens
Department of Internal Medicine, St Antonius Hospital, Nieuwegein, The Netherlands
J Lab Clin Med 144:100-7. 2004..04). These results show that dalteparin is at least as effective as UFH in reducing coagulation activity and perfusion abnormalities in the early treatment of pulmonary embolism...
No influence of heparin plasma and other (pre)analytic variables on D-dimer determinationsRoger E G Schutgens
Department of Internal Medicine, St. Antonius Hospital Koekoekslaan 1, PO Box 2500, 3430 EM Nieuwegein, The Netherlands
Clin Chem 48:1611-3. 2002
The usefulness of five D-dimer assays in the exclusion of deep venous thrombosisR E G Schutgens
Department of Internal Medicine, St Antonius Hospital, Nieuwegein, The Netherlands
J Thromb Haemost 1:976-81. 2003..d-Dimer assays with a low specificity still necessitate additional diagnostic tests in the majority of the patients...
[Simplified diagnosis of deep venous thrombosis by applying clinical score and D-dimer concentration]R E Schutgens
Universitair Medisch Centrum Utrecht, Afd Hematologie, Heidelberglaan 100, 3584 CX Utrecht
Ned Tijdschr Geneeskd 147:1721-6. 2003..Recent studies show that DVT can safely be excluded on the basis of the combination of a normal D-dimer concentration and a low clinical score alone...
The predictive value of D-dimer measurement for cancer in patients with deep vein thrombosisRoger E G Schutgens
Department of Hematology, University Hospital Utrecht, The Netherlands
Haematologica 90:214-9. 2005..The aim of this study was to evaluate the value of D-dimer concentration in predicting cancer in patients with DVT...
No firm association between N-terminal pro-brain natriuretic peptide and percentage of pulmonary vascular obstruction in patients with acute pulmonary embolismM J Agterof
Department of Internal Medicine, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Thromb Res 127:547-50. 2011..We postulated that NT-proBNP is associated with the amount of perfusion defects, expressed as the PVO, on perfusion scintigraphy...
Reduced efficacy of clinical probability score and D-dimer assay in elderly subjects suspected of having deep vein thrombosisRoger E G Schutgens
Haematology, University Hospital Utrecht, Utrecht, The Netherlands
Br J Haematol 129:653-7. 2005..8 years) versus 25% in younger patients (P = 0.00005). We therefore conclude that the combined strategy of a low/moderate PCP score with a normal D-dimer test is safe for excluding DVT in all age groups, but is less useful in the elderly...
The role of fibrin monomers in optimizing the diagnostic work-up of deep vein thrombosisRoger E G Schutgens
Department of Haematology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Thromb Haemost 97:807-13. 2007..In patients with abnormal D-dimer concentrations and a normal US, a normal FM test might be able to replace the second US...
Usefulness of a semiquantitative D-dimer test for the exclusion of deep venous thrombosis in outpatientsRoger E G Schutgens
Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands
Am J Med 112:617-21. 2002..D-dimer tests in patients with cancer and in patients over 70 years old may not be worthwhile, because the tests are usually positive...
