Henk L Smits

Summary

Affiliation: Royal Tropical Institute
Country: The Netherlands

Publications

  1. pmc Multi-locus variable-number tandem repeat profiling of Salmonella enterica serovar Typhi isolates from blood cultures and gallbladder specimens from Makassar, South-Sulawesi, Indonesia
    Mochammad Hatta
    Department of Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia
    PLoS ONE 6:e24983. 2011
  2. ncbi request reprint Brucellosis seroprevalence in Bali cattle with reproductive failure in South Sulawesi and Brucella abortus biovar 1 genotypes in the Eastern Indonesian archipelago
    Hanah Muflihanah
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, 1105AZ, Amsterdam, The Netherlands
    BMC Vet Res 9:233. 2013
  3. ncbi request reprint Brucellosis in pastoral and confined livestock: prevention and vaccination
    H L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Rev Sci Tech 32:219-28. 2013
  4. doi request reprint Limitations of typhoid fever diagnostics and the need for prevention
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, Amsterdam, 1105AZ, The Netherlands
    Expert Rev Mol Diagn 13:147-9. 2013
  5. doi request reprint Prospects for the control of neglected tropical diseases by mass drug administration
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Institute voor de Tropen KIT, Meibergdreef 39, 1105 AZ, Amsterdam, The Netherlands
    Expert Rev Anti Infect Ther 7:37-56. 2009
  6. doi request reprint MLVA genotyping of human Brucella isolates from Peru
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Trans R Soc Trop Med Hyg 103:399-402. 2009
  7. pmc International multicenter evaluation of the clinical utility of a dipstick assay for detection of Leptospira-specific immunoglobulin M antibodies in human serum specimens
    H L Smits
    Department for Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    J Clin Microbiol 37:2904-9. 1999
  8. ncbi request reprint Brucellosis in India: a deceptive infectious disease
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen, Amsterdam, The Netherlands
    Indian J Med Res 122:375-84. 2005
  9. pmc Immunochromatographic Brucella-specific immunoglobulin M and G lateral flow assays for rapid serodiagnosis of human brucellosis
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Amsterdam, The Netherlands
    Clin Diagn Lab Immunol 10:1141-6. 2003
  10. pmc Lateral-flow assay for rapid serodiagnosis of human leptospirosis
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    Clin Diagn Lab Immunol 8:166-9. 2001

Collaborators

  • R A Hartskeerl
  • C Yersin
  • S Sugathan
  • Jairo Gooskens
  • Marga G A Goris
  • A Rocha
  • Encarnacion Clavijo
  • T Masuzawa
  • Javier Solera
  • David L Blazes
  • P N Levett
  • Aysin Zeytinoglu
  • Mochammad Hatta
  • Theresia H Abdoel
  • María Pía Franco
  • Rob Pastoor
  • Maximilian Mulder
  • Theresia Abdoel
  • Robert H Gilman
  • Kathlène S J S M Maas
  • Hanah Muflihanah
  • Andi R Sultan
  • - Ratnawati
  • Marjorie Mendoza-Núñez
  • Melissa Mendez
  • Eric Hall
  • Jesus Chacaltana
  • Milagros Zavaleta
  • Maria L Castañeda
  • Elena Yagui
  • Benjamin Espinosa
  • Nilo Bonifacio
  • Tran T T Nga
  • Sukran Kose
  • Mohammedreza R Hasanjani Roushan
  • Hasan Irmak
  • C K Eapen
  • M Hussein Gasem
  • Ente Rood
  • Pauline Scheelbeek
  • Ibrahim Labeda
  • Ressy Dwiyanti
  • Pauline F D Scheelbeek
  • Regina Cardoso
  • Zósimo Yausen
  • Pilar Osorio
  • Isabel Travassos Dias
  • Pilar Tuesta
  • Nancy Cordova
  • Laura Castañeda Castañeda
  • Jenny Manrique
  • Jennie Manrique
  • Alfredo Guillen
  • Yusuf Ozbel
  • Peter J de Vries
  • M J Soleimani Amin
  • Hayrettin Akdeniz
  • A Pekcan Demiroz
  • Turan Buzgan
  • Omer Evirgen
  • Mariamma Kuriakose
  • Wil M V Dolmans
  • Evy Heerkens
  • Halim Mubin

Detail Information

Publications35

  1. pmc Multi-locus variable-number tandem repeat profiling of Salmonella enterica serovar Typhi isolates from blood cultures and gallbladder specimens from Makassar, South-Sulawesi, Indonesia
    Mochammad Hatta
    Department of Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia
    PLoS ONE 6:e24983. 2011
    ..The high diversity in S. Typhi genotypes circulating in Makassar indicates that the number of carriers could be very large, which may complicate disease prevention and control...
  2. ncbi request reprint Brucellosis seroprevalence in Bali cattle with reproductive failure in South Sulawesi and Brucella abortus biovar 1 genotypes in the Eastern Indonesian archipelago
    Hanah Muflihanah
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, 1105AZ, Amsterdam, The Netherlands
    BMC Vet Res 9:233. 2013
    ..The control of brucellosis requires a major and prolonged effort and confirmation of the infection by isolation with detailed knowledge of the spread of the infection is essential when planning a control program...
  3. ncbi request reprint Brucellosis in pastoral and confined livestock: prevention and vaccination
    H L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Rev Sci Tech 32:219-28. 2013
    ..Although test and slaughter may be an option for the management of remaining or re-emerging foci of infection, such a strategy is frequently not an option because of the cost...
  4. doi request reprint Limitations of typhoid fever diagnostics and the need for prevention
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, Amsterdam, 1105AZ, The Netherlands
    Expert Rev Mol Diagn 13:147-9. 2013
    ..Described PCR assays for typhoid fever have not been validated against bone marrow culture, the gold standard, and their diagnostic utility remains to be established...
  5. doi request reprint Prospects for the control of neglected tropical diseases by mass drug administration
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Institute voor de Tropen KIT, Meibergdreef 39, 1105 AZ, Amsterdam, The Netherlands
    Expert Rev Anti Infect Ther 7:37-56. 2009
    ..Given the risk for the development of drug resistance and the need for a high degree of participation, close attention should be paid to the monitoring of the coverage and efficacy of the different program components...
  6. doi request reprint MLVA genotyping of human Brucella isolates from Peru
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Trans R Soc Trop Med Hyg 103:399-402. 2009
    ..The Peruvian strains were clearly distinct from the East and West Mediterranean groups of B. melitensis genotypes, suggesting that they may constitute a unique Latin American cluster...
  7. pmc International multicenter evaluation of the clinical utility of a dipstick assay for detection of Leptospira-specific immunoglobulin M antibodies in human serum specimens
    H L Smits
    Department for Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    J Clin Microbiol 37:2904-9. 1999
    ....
  8. ncbi request reprint Brucellosis in India: a deceptive infectious disease
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen, Amsterdam, The Netherlands
    Indian J Med Res 122:375-84. 2005
    ..Alertness of medical staff is needed to recognize and diagnose the disease. Awareness of risk groups is needed to take appropriate preventive measures and to accept control measures...
  9. pmc Immunochromatographic Brucella-specific immunoglobulin M and G lateral flow assays for rapid serodiagnosis of human brucellosis
    Henk L Smits
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Amsterdam, The Netherlands
    Clin Diagn Lab Immunol 10:1141-6. 2003
    ..Together these characteristics indicate that the Brucella IgM and IgG flow assays are ideal for use in clinical settings in rural and suburban areas in which brucellosis is endemic...
  10. pmc Lateral-flow assay for rapid serodiagnosis of human leptospirosis
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    Clin Diagn Lab Immunol 8:166-9. 2001
    ..The assay is read after 10 min, and a positive result is obtained when staining of the test line is observed...
  11. pmc Development and evaluation of a rapid dipstick assay for serodiagnosis of acute human brucellosis
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, The Netherlands
    J Clin Microbiol 37:4179-82. 1999
    ..All of these factors make the test ideal for developing countries and rural settings...
  12. pmc Simple latex agglutination assay for rapid serodiagnosis of human leptospirosis
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, 1105 AZ Amsterdam, The Netherlands
    J Clin Microbiol 38:1272-5. 2000
    ..The reagents have a long shelf life, even at tropical temperatures. Together, these factors make the assay suitable for use even at the peripheral level of a health care system as a rapid screening test for leptospirosis...
  13. ncbi request reprint International multi-centre evaluation of a dipstick assay for human leptospirosis
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    Trop Med Int Health 5:124-8. 2000
    ..It is also easy to use and does not require special equipment or refrigeration. Therefore the assay is ideal for use in developing countries and rural settings...
  14. ncbi request reprint Latex based, rapid and easy assay for human leptospirosis in a single test format
    H L Smits
    Department of Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands
    Trop Med Int Health 6:114-8. 2001
    ..2% for samples collected at a later stage. The specificity was 93.9% and 89.8%, respectively. These characteristics make the test ideal for use in areas where the disease is common and where laboratory support is not routinely available...
  15. doi request reprint Simple and rapid field tests for brucellosis in livestock
    Theresia Abdoel
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, Amsterdam, The Netherlands
    Vet Microbiol 130:312-9. 2008
    ..However, as expected, some degree of reactivity was observed when testing selected serum samples that reacted non-specific in reference tests for brucellosis...
  16. doi request reprint Simple, rapid, and affordable point-of-care test for the serodiagnosis of typhoid fever
    Rob Pastoor
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Amsterdam, The Netherlands
    Diagn Microbiol Infect Dis 61:129-34. 2008
    ..Because of its simplicity, the assay may also be used as a field test in remote areas...
  17. ncbi request reprint Antibody response in typhoid fever in endemic Indonesia and the relevance of serology and culture to diagnosis
    Mochammad Hatta
    Department of Medical Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
    Southeast Asian J Trop Med Public Health 33:742-51. 2002
    ..Duration of illness and presence of S. typhi in the blood are major factors that determine severity of disease...
  18. ncbi request reprint Rapid latex agglutination test for the serodiagnosis of human brucellosis
    Theresia H Abdoel
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, 1105 AZ Amsterdam, The Netherlands
    Diagn Microbiol Infect Dis 57:123-8. 2007
    ..2% (95% CI, 96-99). The assay is ideal for use as a field test in remote areas and as point-of-care test in hospitals and health care centers that lack the expertise and facilities to perform the more demanding classic serologic tests...
  19. pmc New flagellin gene for Salmonella enterica serovar Typhi from the East Indonesian archipelago
    Mochammad Hatta
    Department of Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia
    Am J Trop Med Hyg 84:429-34. 2011
    ..The Hj gene was not detected. The z66 gene was present in 15.4% of the isolates. The presence of these "foreign" flagellin genes could be associated with an increased risk for developing severe disease...
  20. ncbi request reprint Laboratory evaluation of a simple and rapid latex agglutination assay for the serodiagnosis of typhoid fever
    Theresia H Abdoel
    KIT Biomedical Research, Royal Tropical Institute Koninklijk Instituut voor de Tropen KIT, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands
    Trans R Soc Trop Med Hyg 101:1032-8. 2007
    ..5% for samples collected between days 7 and 9, and to 84.6% for the samples collected more than 9 days after the onset of illness. Testing of follow-up samples may further improve sensitivity by demonstrating seroconversion...
  21. ncbi request reprint Simple dipstick assay for the detection of Salmonella typhi-specific IgM antibodies and the evolution of the immune response in patients with typhoid fever
    Mochammad Hatta
    Department of Microbiology, Hasanuddin University, Makassar, Indonesia
    Am J Trop Med Hyg 66:416-21. 2002
    ..The stability of the reagents of the dipstick and the simplicity of the assay allows its use in places that lack laboratory facilities...
  22. ncbi request reprint Detection of Salmonella typhi by nested polymerase chain reaction in blood, urine, and stool samples
    Mochammad Hatta
    Department of Medical Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia
    Am J Trop Med Hyg 76:139-43. 2007
    ..These results show that the PCR with blood is a sensitive method for the diagnosis of typhoid fever, and that the PCRs with urine and feces could be useful complementary tests...
  23. ncbi request reprint Evaluation of brucellosis by PCR and persistence after treatment in patients returning to the hospital for follow-up
    Kathlène S J S M Maas
    KIT Biomedical Research, Amsterdam, The Netherlands
    Am J Trop Med Hyg 76:698-702. 2007
    ..Thus, Brucella DNA may persist in the serum weeks to months after completion of the standard treatment regimen...
  24. ncbi request reprint Point-of-care testing for malaria outbreak management
    - Ratnawati
    Department of Parasitology, Hasanuddin University, Makassar, Indonesia
    Trans R Soc Trop Med Hyg 102:699-704. 2008
    ..0%) was slightly higher than that of microscopy (87.6%). The result indicates that rapid antigen detection for malaria could be a useful alternative to microscopy to reduce the workload during emergency outbreak situations...
  25. ncbi request reprint Comparison of Brucella immunoglobulin M and G flow assays with serum agglutination and 2-mercaptoethanol tests in the diagnosis of brucellosis
    Aysin Zeytinoglu
    Ege University Medical Faculty, Department of Microbiology and Clinical Microbiology, Izmir, Turkey
    Clin Chem Lab Med 44:180-4. 2006
    ..The flow assays are very useful, especially in rural settings where brucellosis is widespread and where well-equipped laboratories to perform the laboratory tests are not readily available...
  26. pmc Comparison of a dipstick assay for detection of Brucella-specific immunoglobulin M antibodies with other tests for serodiagnosis of human brucellosis
    Encarnacion Clavijo
    Microbiology Unit, HCU Virgen de la Victoria, Malaga, Spain
    Clin Diagn Lab Immunol 10:612-5. 2003
    ..Under laboratory conditions this test has the advantage of being quick and IgM antibody-specific...
  27. ncbi request reprint Use of the Brucella IgM and IgG flow assays in the serodiagnosis of human brucellosis in an area endemic for brucellosis
    Hasan Irmak
    Department of Infectious Diseases and Clinical Microbiology, Yuzuncu Yil University, Van, Turkey
    Am J Trop Med Hyg 70:688-94. 2004
    ..The agreement was 92%. Application of the flow assays on serum samples collected during a village survey for brucellosis after an outbreak demonstrated their diagnostic potential as field tests...
  28. ncbi request reprint Application of a user-friendly Brucella-specific IgM and IgG antibody assay for the rapid confirmation of Rose Bengal-positive patients in a hospital in Iran
    Mohammedreza R Hasanjani Roushan
    Yahyanejad Hospital, Babol Medical University, Babol, Islamic Republic of Iran
    Trans R Soc Trop Med Hyg 99:744-50. 2005
    ....
  29. ncbi request reprint Brucellosis is not a major cause of febrile illness in patients at public health care facilities in Binh Thuan Province, Vietnam
    Tran T T Nga
    Department of Microbiology, Cho Ray Hospital, Ho Chi Minh City, Vietnam
    J Infect 53:12-5. 2006
    ..To determine the presence of brucellosis among patients with acute febrile illness at health care facilities in Binh Thuan province, Vietnam...
  30. ncbi request reprint Evaluation of the clinical utility of a rapid blood test for human leptospirosis
    C K Eapen
    Malankara Orthodox Syrian Church Medical Mission Hospital, Kolenchery, India
    Diagn Microbiol Infect Dis 42:221-5. 2002
    ..The assay utilizes stabilised components and can be stored without the need for refrigeration. These characteristics make the assay ideal in areas where the disease is common and where laboratory support is not routinely available...
  31. ncbi request reprint Human brucellosis
    María Pía Franco
    Department of Neurology, University of Minnesota, Minneapolis, MN, USA
    Lancet Infect Dis 7:775-86. 2007
    ..This Review summarises current knowledge of the pathogenic mechanisms, new diagnostic advances, therapeutic options, and the situation of developing countries in regard to human brucellosis...
  32. ncbi request reprint Brucellosis in household members of Brucella patients residing in a large urban setting in Peru
    Marjorie Mendoza-Núñez
    Department of Infectious Diseases, Hospital Nacional Daniel Alcides Carrión, Gaurdia Chalaca 2176, Callao Peru
    Am J Trop Med Hyg 78:595-8. 2008
    ..Although contact with livestock was rare, the consumption of unpasteurized dairy products was reported by almost all patients with brucellosis, their household members, and hospitalized non-brucellosis patients...
  33. ncbi request reprint Prevalence of Brucella antibodies in rural and suburban communities in three provinces of Turkey: need for improved diagnosis and prevention
    Sukran Kose
    Department of Clinical Microbiology and Infectious Diseases, Tepecik Educational Hospital, Yenisehir, Izmir, Turkey
    J Infect 53:308-14. 2006
    ..To determine the seroprevalence of Brucella-specific antibodies in rural and suburban communities in different provinces of Anatolia...
  34. ncbi request reprint Persistence and relapse in brucellosis and need for improved treatment
    María Pía Franco
    Asociación Benéfica Proyectos en Informática, Salud, Medicina y Agricultura A B PRISMA, Lima, Peru
    Trans R Soc Trop Med Hyg 101:854-5. 2007
    ..Use of DNA detection as a marker for treatment success and for the prediction of relapse requires confirmation. In the absence of simple and effective treatment regimens, patient education to promote compliance is essential...
  35. ncbi request reprint Evaluation of a simple and rapid dipstick assay for the diagnosis of typhoid fever in Indonesia
    M Hussein Gasem
    Department of Medicine, Dr Kariadi Hospital and Faculty of Medicine, Diponegoro University, Semarang, Indonesia
    J Med Microbiol 51:173-7. 2002
    ..The assay uses stabilised components that can be stored outside the refrigerator, does not require special equipment, and may be of use in remote health facilities that have no culture facilities...