J P Boon

Summary

Affiliation: Royal Netherlands Institute for Sea Research
Country: The Netherlands

Publications

  1. ncbi Levels of polybrominated diphenyl ether (PBDE) flame retardants in animals representing different trophic levels of the North Sea food Web
    Jan P Boon
    Royal Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Environ Sci Technol 36:4025-32. 2002
  2. ncbi The use of microsomal in vitro assay to study phase I biotransformation of chlorobornanes (Toxaphene) in marine mammals and birds. Possible consequences of biotransformation for bioaccumulation and genotoxicity
    J P Boon
    Netherlands Institute for Sea Research NIOZ, Texel, The Netherlands
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:385-403. 1998
  3. ncbi Immunochemical and catalytic characterization of hepatic microsomal cytochrome P450 in the sperm whale (Physeter macrocephalus)
    J P Boon
    Netherlands Institute for Sea Research NIOZ, PO Box 59, 1790 AB Den Burg, Texel, Netherlands
    Aquat Toxicol 52:297-309. 2001
  4. ncbi The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses
    J P Boon
    Royal Netherlands Institute for Sea Research NIOZ, Department of Marine Biogeochemistry and Toxicology, Texel
    Mar Environ Res 54:719-24. 2002
  5. ncbi Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes
    C M van Hezik
    Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Aquat Toxicol 51:319-33. 2001
  6. ncbi Imposex and organotin concentrations in Buccinum undatum and Neptunea antiqua from the North Sea: relationship to shipping density and hydrographical conditions
    Cato C ten Hallers-Tjabbes
    Royal Netherlands Institute für Sea Research NIOZ, PO Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Mar Environ Res 55:203-33. 2003
  7. ncbi Levels of some polybrominated diphenyl ether (PBDE) flame retardants along the Dutch coast as derived from their accumulation in SPMDs and blue mussels (Mytilus edulis)
    Kees Booij
    Netherlands Institute for Sea Research NIOZ, Den Burg, Texel, The Netherlands
    Chemosphere 46:683-8. 2002
  8. ncbi Levels of hexabromocyclododecane in harbor porpoises and common dolphins from western European seas, with evidence for stereoisomer-specific biotransformation by cytochrome p450
    Bart N Zegers
    Royal Netherlands Institute for Sea Research NIOZ, 1790 AB Den Burg, Texel
    Environ Sci Technol 39:2095-100. 2005
  9. ncbi Levels of polybrominated diphenyl ether flame retardants in sediment cores from Western Europe
    Bart N Zegers
    Royal Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Environ Sci Technol 37:3803-7. 2003
  10. ncbi Variations in spatial and temporal distribution of Archaea in the North Sea in relation to environmental variables
    Lydie Herfort
    Department of Marine Biogeochemistry and Toxicology, Royal Netherlands Institute for Sea Research NIOZ, Texel, The Netherlands
    FEMS Microbiol Ecol 62:242-57. 2007

Collaborators

Detail Information

Publications16

  1. ncbi Levels of polybrominated diphenyl ether (PBDE) flame retardants in animals representing different trophic levels of the North Sea food Web
    Jan P Boon
    Royal Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Environ Sci Technol 36:4025-32. 2002
    ..This has serious consequences for the route of elimination of POPs, since their elimination from the blood into the ambient seawater via the gill-membrane is no longer possible...
  2. ncbi The use of microsomal in vitro assay to study phase I biotransformation of chlorobornanes (Toxaphene) in marine mammals and birds. Possible consequences of biotransformation for bioaccumulation and genotoxicity
    J P Boon
    Netherlands Institute for Sea Research NIOZ, Texel, The Netherlands
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:385-403. 1998
    ..Some precautions are discussed, that should be taken to reduce the chance of false negative results...
  3. ncbi Immunochemical and catalytic characterization of hepatic microsomal cytochrome P450 in the sperm whale (Physeter macrocephalus)
    J P Boon
    Netherlands Institute for Sea Research NIOZ, PO Box 59, 1790 AB Den Burg, Texel, Netherlands
    Aquat Toxicol 52:297-309. 2001
    ..In contrast, 3,3',4,4'-tetrachlorobiphenyl (CB-77) and two chlorobornanes (CHB-32 and CHB-62) occurring in the insectide toxaphene(R), were not metabolised...
  4. ncbi The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses
    J P Boon
    Royal Netherlands Institute for Sea Research NIOZ, Department of Marine Biogeochemistry and Toxicology, Texel
    Mar Environ Res 54:719-24. 2002
    ....
  5. ncbi Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes
    C M van Hezik
    Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Aquat Toxicol 51:319-33. 2001
    ..Stereochemical preferences of biotransformation enzymes can have an influence on the environmental distribution of both enantiomers of optically active compounds...
  6. ncbi Imposex and organotin concentrations in Buccinum undatum and Neptunea antiqua from the North Sea: relationship to shipping density and hydrographical conditions
    Cato C ten Hallers-Tjabbes
    Royal Netherlands Institute für Sea Research NIOZ, PO Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Mar Environ Res 55:203-33. 2003
    ..5 and 93%. This parameter might be a useful indicator to compare past and present densities of populations of both species in different areas of the North Sea...
  7. ncbi Levels of some polybrominated diphenyl ether (PBDE) flame retardants along the Dutch coast as derived from their accumulation in SPMDs and blue mussels (Mytilus edulis)
    Kees Booij
    Netherlands Institute for Sea Research NIOZ, Den Burg, Texel, The Netherlands
    Chemosphere 46:683-8. 2002
    ..Depuration experiments showed that the larger part of the BDE209 content in mussels was associated with ingested particles, whereas no such effect was observed for the other BDEs or PCBs...
  8. ncbi Levels of hexabromocyclododecane in harbor porpoises and common dolphins from western European seas, with evidence for stereoisomer-specific biotransformation by cytochrome p450
    Bart N Zegers
    Royal Netherlands Institute for Sea Research NIOZ, 1790 AB Den Burg, Texel
    Environ Sci Technol 39:2095-100. 2005
    ....
  9. ncbi Levels of polybrominated diphenyl ether flame retardants in sediment cores from Western Europe
    Bart N Zegers
    Royal Netherlands Institute for Sea Research NIOZ, P O Box 59, 1790 AB Den Burg, Texel, The Netherlands
    Environ Sci Technol 37:3803-7. 2003
    ....
  10. ncbi Variations in spatial and temporal distribution of Archaea in the North Sea in relation to environmental variables
    Lydie Herfort
    Department of Marine Biogeochemistry and Toxicology, Royal Netherlands Institute for Sea Research NIOZ, Texel, The Netherlands
    FEMS Microbiol Ecol 62:242-57. 2007
    ....
  11. ncbi Distribution and fate of HBCD and TBBPA brominated flame retardants in North Sea estuaries and aquatic food webs
    Steven Morris
    Centre for Environment, Fisheries and Aquaculture Science, Weymouth Laboratory, Weymouth, Dorset, United Kingdom DT4 8UB
    Environ Sci Technol 38:5497-504. 2004
    ..This study shows evidence of HBCD bioaccumulation at the trophic level and biomagnification in the ascending aquatic food chain, and these findings justify risk assessment studies at the ecosystem level...
  12. ncbi Atmospheric transport of polybrominated diphenyl ethers and polychlorinated biphenyls to the Baltic Sea
    Arnout F H ter Schure
    Chemical Ecology and Ecotoxicology, Department of Ecology, Lund University, Ecology Building, S 223 62 Lund, Sweden
    Environ Sci Technol 38:1282-7. 2004
    ..The calculated yearly deposition of PBDEs and PCBs indicated that the atmospheric input of PBDEs to the Baltic Proper is currently exceeding that of the PCBs by a factor of 40, while that of the PCBs is decreasing...
  13. ncbi Levels and trends of polybrominated diphenylethers and other brominated flame retardants in wildlife
    Robin J Law
    Centre for Environment, Fisheries and Aquaculture Science, CEFAS Burnham Laboratory, Remembrance Avenue, Burnham on Crouch, Essex CM0 8HA, UK
    Environ Int 29:757-70. 2003
    ....
  14. ncbi Hepatic microsomal cytochrome P450 enzyme activity in relation to in vitro metabolism/inhibition of polychlorinated biphenyls and testosterone in Baltic grey seal (Halichoerus grypus)
    Hongxia Li
    Great Lakes Institute for Environmental Research, University of Windsor, Windsor, Ontario N9B 3P4, Canada
    Environ Toxicol Chem 22:636-44. 2003
    ..Defining the profiles of CYP enzymes that are responsible for PCB biotransformation is necessary to fully understand the bioaccumulation, toxicokinetics, and risk of PCB exposure in seals and other free-ranging marine mammals...
  15. ncbi Quantitative structure-activity relationship modeling on in vitro endocrine effects and metabolic stability involving 26 selected brominated flame retardants
    Mikael Harju
    Environmental Chemistry, Department of Chemistry, Umea University, SE 90187 Umea, Sweden
    Environ Toxicol Chem 26:816-26. 2007
    ..Predictions made for the constituents of the technical flame retardant Bromkal 70-5DE found BDE 17 to be a potent androgen antagonist and BDE 66, which is a relevant PBDE in environmental samples, to be only a weak antagonist...
  16. ncbi Radiocarbon content of synthetic and natural semi-volatile halogenated organic compounds
    Christopher M Reddy
    Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, MA 02543, USA
    Environ Pollut 120:163-8. 2002
    ....