T B Vree

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy dogs
    T B Vree
    Institute for Anaesthesiology, University Medical Center Sint Radboud, Nijmegen, The Netherlands
    J Vet Pharmacol Ther 26:165-71. 2003
  2. ncbi request reprint Clinical pharmacology and the use of articaine for local and regional anaesthesia
    Tom B Vree
    Institute for Anaesthesia, University Medical Centre St Radboud, PO Box 9101, 6500HB Nijmegen, The Netherlands
    Best Pract Res Clin Anaesthesiol 19:293-308. 2005
  3. ncbi request reprint Sex-related differences in the pharmacokinetics of isosorbide-5-mononitrate (60 mg) after repeated oral administration of two different original prolonged release formulations
    T B Vree
    Institute for Anesthesiology, University Medical Centre, Nijmegen Sint Radboud, The Netherlands
    Int J Clin Pharmacol Ther 42:463-72. 2004
  4. ncbi request reprint Lack of male-female differences in disposition and esterase hydrolysis of ramipril to ramiprilat in healthy volunteers after a single oral dose
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Nijmegen Sint Radboud, Nijmegen, The Netherlands
    ScientificWorldJournal 3:1332-43. 2003
  5. ncbi request reprint Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers:gut hydrolysis of lovastatin is twice that of simvastatin
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Nijmegen Sint Radboud, Nijmegen, The Netherlands
    ScientificWorldJournal 3:1332-43. 2003
  6. ncbi request reprint Pharmacokinetics and toxicology of sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radboud Hospital, Nijmegen, The Netherlands
    Cancer Chemother Pharmacol 20:115-24. 1987
  7. ncbi request reprint Pharmacokinetics of the antitumor antibiotic n-pentyl-sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radboud University Hospital, Nijmegen, The Netherlands
    Invest New Drugs 8:25-32. 1990
  8. ncbi request reprint Preclinical pharmacokinetics of the antitumor antibiotic deshydroxy-sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radbound University Hospital, Nijmegen, The Netherlands
    Anticancer Res 8:1381-5. 1988
  9. ncbi request reprint Identical pattern of highly variable absorption of clavulanic acid from four different oral formulations of co-amoxiclav in healthy subjects
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Sint Radboud, PO Box 9101, 6500 HB Nijmegen
    J Antimicrob Chemother 51:373-8. 2003
  10. ncbi request reprint Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy cats
    Tom B Vree
    Institute for Anaesthesiology, University Medical Center Sint Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    ScientificWorldJournal 2:1369-78. 2002

Collaborators

  • Stefan Horkovics-Kovats
  • Leo H D J Booij
  • Anneleen Kuijsten
  • Marc A M Simon
  • Peter C H Hollman
  • Ilja C W Arts
  • Aart J Lagerwerf
  • Mathieu J M Gielen
  • Z Zylicz
  • L A van den Broek
  • D J Wagener
  • E van der Kleijn
  • M Garzotto
  • H C Ottenheijm
  • U van Haelst
  • J M Wessels
  • H van Rennes
  • B Winograd
  • P Fernandez del Moral

Detail Information

Publications12

  1. ncbi request reprint Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy dogs
    T B Vree
    Institute for Anaesthesiology, University Medical Center Sint Radboud, Nijmegen, The Netherlands
    J Vet Pharmacol Ther 26:165-71. 2003
    ..The mean ratio of the AUCt amoxicillin : clavulanic acid was 12.7 +/- 3.65 for formulation A and 11.8 +/- 5.22 for formulation B (P = 0.51)...
  2. ncbi request reprint Clinical pharmacology and the use of articaine for local and regional anaesthesia
    Tom B Vree
    Institute for Anaesthesia, University Medical Centre St Radboud, PO Box 9101, 6500HB Nijmegen, The Netherlands
    Best Pract Res Clin Anaesthesiol 19:293-308. 2005
    ....
  3. ncbi request reprint Sex-related differences in the pharmacokinetics of isosorbide-5-mononitrate (60 mg) after repeated oral administration of two different original prolonged release formulations
    T B Vree
    Institute for Anesthesiology, University Medical Centre, Nijmegen Sint Radboud, The Netherlands
    Int J Clin Pharmacol Ther 42:463-72. 2004
    ..To identify differences in the disposition of isosorbide-5-mononitrate between male and female volunteers...
  4. ncbi request reprint Lack of male-female differences in disposition and esterase hydrolysis of ramipril to ramiprilat in healthy volunteers after a single oral dose
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Nijmegen Sint Radboud, Nijmegen, The Netherlands
    ScientificWorldJournal 3:1332-43. 2003
    ..With a fixed dose (5 mg), females received a higher dose/kg than males and consequently showed a higher AUCt/kg of the active metabolite ramiprilat...
  5. ncbi request reprint Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers:gut hydrolysis of lovastatin is twice that of simvastatin
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Nijmegen Sint Radboud, Nijmegen, The Netherlands
    ScientificWorldJournal 3:1332-43. 2003
    ..The extra methyl group in simvastatin results in less hydrolysis due to steric hindrance...
  6. ncbi request reprint Pharmacokinetics and toxicology of sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radboud Hospital, Nijmegen, The Netherlands
    Cancer Chemother Pharmacol 20:115-24. 1987
    ..Two out of five dogs developed hemorrhagic diathesis due to hypofibrinogenemia and deficiency of other blood-coagulation factors. Sparsomycin was not toxic to the bone marrow...
  7. ncbi request reprint Pharmacokinetics of the antitumor antibiotic n-pentyl-sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radboud University Hospital, Nijmegen, The Netherlands
    Invest New Drugs 8:25-32. 1990
    ..The non-renal clearance was saturable at higher doses of PSm and was the reason for non-linearity of pharmacokinetics...
  8. ncbi request reprint Preclinical pharmacokinetics of the antitumor antibiotic deshydroxy-sparsomycin in beagle dogs
    Z Zylicz
    Department of Internal Medicine, St Radbound University Hospital, Nijmegen, The Netherlands
    Anticancer Res 8:1381-5. 1988
    ..The pharmacokinetics was linear until the lethal dose. The results of this study provided additional data useful in selection of potentially useful analogues for further preclinical studies...
  9. ncbi request reprint Identical pattern of highly variable absorption of clavulanic acid from four different oral formulations of co-amoxiclav in healthy subjects
    Tom B Vree
    Institute for Anaesthesiology, University Medical Centre Sint Radboud, PO Box 9101, 6500 HB Nijmegen
    J Antimicrob Chemother 51:373-8. 2003
    ..We conclude that the absorption of clavulanic acid, after oral administration, is highly variable and may vary over a five-fold range between patients...
  10. ncbi request reprint Variable absorption of clavulanic acid after an oral dose of 25 mg/kg of Clavubactin and Synulox in healthy cats
    Tom B Vree
    Institute for Anaesthesiology, University Medical Center Sint Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    ScientificWorldJournal 2:1369-78. 2002
    ....
  11. ncbi request reprint Similar motor block effects and disposition kinetics between lidocaine and (+/-)mepivacaine in patients undergoing axillary brachial plexus block during day case surgery
    Marc A M Simon
    Department of Anaesthesiology, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER Enschede, Netherlands
    ScientificWorldJournal 2:1306-19. 2002
    ....
  12. ncbi request reprint Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside
    Anneleen Kuijsten
    RIKILT Institute of Food Safety, Wageningen UR, 6700 AE Wageningen, The Netherlands
    J Nutr 135:795-801. 2005
    ..Therefore, plasma enterolignan concentrations are expected to be good biomarkers of dietary lignan exposure and can be used to evaluate the effects of lignans...