Research Topics
Species | M C VonkSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
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Detail Information
Publications
Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive diseaseMaria J Overbeek
Department of Pulmonary Diseases, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
Arthritis Res Ther 13:R61. 2011..Immunoreactivity patterns of phosphorylated PDGFR-β (pPDGFR-β) and the ligand PDGF-B were evaluated to provide more insight into the patterns of PDGFR-b activation...
Systemic sclerosis and its pulmonary complications in The Netherlands: an epidemiological studyM C Vonk
Department of Rheumatology, Cardiology of the Radboud University Nijmegen Medical Centre, The Netherlands
Ann Rheum Dis 68:961-5. 2009..The same holds true for its leading causes of death: pulmonary fibrosis and pulmonary arterial hypertension (PAH), for which effective treatment options have recently become available...
Right ventricle Tei-index: a tool to increase the accuracy of non-invasive detection of pulmonary arterial hypertension in connective tissue diseasesM C Vonk
Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Eur J Echocardiogr 8:317-21. 2007....
Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosisM C Vonk
Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Ann Rheum Dis 67:98-104. 2008..This study reports the effects on survival, skin and major organ function of HSCT in patients with severe diffuse cutaneous SSc...
Oesophageal dilatation on high-resolution computed tomography scan of the lungs as a sign of sclerodermaM C Vonk
Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Ann Rheum Dis 67:1317-21. 2008..The objective of this study is to evaluate the predictive value of oesophageal dilatation on the HRCT scan for the diagnosis of SSc...
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediatorsJ C A Broen
Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Arthritis Rheum 64:264-71. 2012..To investigate whether polymorphisms in Toll-like receptor (TLR) genes, previously reported to be associated with immune-mediated diseases, are involved in systemic sclerosis (SSc)...
Enhanced interleukin-10 production by dendritic cells upon stimulation with Toll-like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretionA W T van Lieshout
Department of Rheumatology, Radboud University Nijmegen Medical Centre, The Netherlands
Scand J Rheumatol 38:282-90. 2009..The aim of our study was to determine whether Toll-like receptor (TLR)-mediated stimulation of monocytes and dendritic cells (DCs) contributes to the higher levels of CCL18 in SSc...
Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stressH Hargardóttir
Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, The Netherlands
Scand J Rheumatol 39:63-70. 2010..The aim of this study was to determine exercise-induced inflammatory and oxidative responses in SSc compared with healthy subjects...
Clinical prediction of 5-year survival in systemic sclerosis: validation of a simple prognostic model in EUSTAR centresJ Fransen
Correspondence to J Fransen, Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Ann Rheum Dis 70:1788-92. 2011..A study was undertaken to validate the prognostic model to predict 5-year survival in SSc in other centres throughout Europe...
Pulmonary hypertension: its diagnosis and management, a multidisciplinary approachM C Vonk
Department of Rheumatic Diseases, Radboud University Nijmegen Medical Centre, The Netherlands
Neth J Med 63:193-8. 2005..The diagnostic protocol used in our hospital is presented along with a description of two case histories. An algorithm of the different therapeutic strategies now available is given as well as recommendations for follow-up...
Appearance self-esteem in systemic sclerosis--subjective experience of skin deformity and its relationship with physician-assessed skin involvement, disease status and psychological variablesW G J M van Lankveld
1Department of Rheumatology, St Maartenskliniek, Nijmegen, The Netherlands
Rheumatology (Oxford) 46:872-6. 2007..To determine the importance of skin deformity in systemic sclerosis (SSc) relative to other disease stressors and to find psychological correlates of appearance self-esteem (ASE) after controlling for disease status...
