M Vaneker

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 107:419-26. 2007
  2. ncbi request reprint Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Anesthesiology 109:465-72. 2008
  3. ncbi request reprint Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice
    M Vaneker
    Departments of Anesthesiology and Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 53:742-8. 2009
  4. doi request reprint Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 111:836-43. 2009
  5. doi request reprint Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice
    S E I VAN DER Wal
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre RUNMC, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 58:487-94. 2014
  6. doi request reprint α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury
    M Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 107:559-66. 2011
  7. ncbi request reprint Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature
    F J J Halbertsma
    Department of Paediatric Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neth J Med 63:382-92. 2005
  8. doi request reprint Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy mice
    Feico J J Halbertsma
    Maxima Medical Centre, Veldhoven, The Netherlands
    Crit Care Med 36:2403-6. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 107:419-26. 2007
    ..To study mechanotransduction in vivo, the authors used an animal MV model with clinically relevant ventilator settings, avoiding alveolar damage...
  2. ncbi request reprint Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Anesthesiology 109:465-72. 2008
    ..A role for proinflammatory pathways has been proposed. The current studies analyzed the roles of Toll-like receptor (TLR) 4 and TLR2 involvement in the inflammatory response after MV in the healthy lung...
  3. ncbi request reprint Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice
    M Vaneker
    Departments of Anesthesiology and Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 53:742-8. 2009
    ..Isoflurane is known to have protective immunological effects on different organ systems. We tested the hypothesis that the MV-induced inflammatory response in healthy lungs is reduced by isoflurane...
  4. doi request reprint Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 111:836-43. 2009
    ....
  5. doi request reprint Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice
    S E I VAN DER Wal
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre RUNMC, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 58:487-94. 2014
    ..Resveratrol (RVT) exhibits anti-inflammatory effects in vitro and in vivo supposedly by interfering with TLR4 signaling and NF-κB. In the present study, we investigated the role of RVT in MV-induced inflammation in mice...
  6. doi request reprint α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury
    M Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 107:559-66. 2011
    ....
  7. ncbi request reprint Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature
    F J J Halbertsma
    Department of Paediatric Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neth J Med 63:382-92. 2005
    ..Mechanical ventilation is known to induce and aggravate lung injury. One of the underlying mechanisms is biotrauma, an inflammatory response in which cytokines play a crucial role...
  8. doi request reprint Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy mice
    Feico J J Halbertsma
    Maxima Medical Centre, Veldhoven, The Netherlands
    Crit Care Med 36:2403-6. 2008
    ....