Nens van Alfen

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. doi request reprint Diagnosis of brachial and lumbosacral plexus lesions
    Nens van Alfen
    Department of Neurology and Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, The Netherlands Electronic address
    Handb Clin Neurol 115:293-310. 2013
  2. pmc Physical training in boys with Duchenne Muscular Dystrophy: the protocol of the No Use is Disuse study
    Merel Jansen
    Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, The Netherlands
    BMC Pediatr 10:55. 2010
  3. ncbi request reprint Long-term pain, fatigue, and impairment in neuralgic amyotrophy
    Nens van Alfen
    Department of Neurology, Neuromuscular Centre Nijmegen, Donders Center for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arch Phys Med Rehabil 90:435-9. 2009
  4. doi request reprint Clinical and pathophysiological concepts of neuralgic amyotrophy
    Nens van Alfen
    920 Clinical Neurophysiology, Department of Neurology, Radboud University Nijmegen Medical Center, Reinier Postlaan 4, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Nat Rev Neurol 7:315-22. 2011
  5. pmc The neuralgic amyotrophy consultation
    Nens van Alfen
    Neurologist, clinical neurophysiologist, Neuromuscular Centre Nijmegen, Dept of Neurology and Clinical Neurophysiology, c o 920 KNF, Radboud University Nijmegen, Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Neurol 254:695-704. 2007
  6. ncbi request reprint The clinical spectrum of neuralgic amyotrophy in 246 cases
    Nens van Alfen
    Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Brain 129:438-50. 2006
  7. pmc Histology of hereditary neuralgic amyotrophy
    N van Alfen
    Neuromuscular Centre Nijmegen, Institute of Neurology, 314 University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Neurol Neurosurg Psychiatry 76:445-7. 2005
  8. doi request reprint The influence of concentration/meditation on autonomic nervous system activity and the innate immune response: a case study
    Matthijs Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Psychosom Med 74:489-94. 2012
  9. doi request reprint Muscles alive: ultrasound detects fibrillations
    Sigrid Pillen
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Clin Neurophysiol 120:932-6. 2009
  10. doi request reprint Atypical dystonic shoulder movements following neuralgic amyotrophy
    William F Abdo
    Institute of Neurology and Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mov Disord 24:293-6. 2009

Collaborators

Detail Information

Publications29

  1. doi request reprint Diagnosis of brachial and lumbosacral plexus lesions
    Nens van Alfen
    Department of Neurology and Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, The Netherlands Electronic address
    Handb Clin Neurol 115:293-310. 2013
    ..This chapter provides an overview of both common and rarer brachial and lumbosacral plexus disorders, focusing on clinical examination, the use of additional investigative techniques, prognosis, and treatment. ..
  2. pmc Physical training in boys with Duchenne Muscular Dystrophy: the protocol of the No Use is Disuse study
    Merel Jansen
    Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, The Netherlands
    BMC Pediatr 10:55. 2010
    ..This paper describes the hypotheses and methods of the NUD study...
  3. ncbi request reprint Long-term pain, fatigue, and impairment in neuralgic amyotrophy
    Nens van Alfen
    Department of Neurology, Neuromuscular Centre Nijmegen, Donders Center for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arch Phys Med Rehabil 90:435-9. 2009
    ..Therefore, the objective of this study was to describe the prevalence of pain, psychologic symptoms, fatigue, functional status, and quality of life in patients with NA...
  4. doi request reprint Clinical and pathophysiological concepts of neuralgic amyotrophy
    Nens van Alfen
    920 Clinical Neurophysiology, Department of Neurology, Radboud University Nijmegen Medical Center, Reinier Postlaan 4, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Nat Rev Neurol 7:315-22. 2011
    ..This Review provides an overview of the current clinical and pathophysiological concepts and research topics in neuralgic amyotrophy...
  5. pmc The neuralgic amyotrophy consultation
    Nens van Alfen
    Neurologist, clinical neurophysiologist, Neuromuscular Centre Nijmegen, Dept of Neurology and Clinical Neurophysiology, c o 920 KNF, Radboud University Nijmegen, Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Neurol 254:695-704. 2007
    ..This article provides a practical overview of current knowledge on the clinical presentation, diagnosis, pathogenesis and the treatment of pain and complications...
  6. ncbi request reprint The clinical spectrum of neuralgic amyotrophy in 246 cases
    Nens van Alfen
    Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Brain 129:438-50. 2006
    ..5% in males), and their functional outcome was worse. Overall recovery was less favourable than usually assumed, with persisting pain and paresis in approximately two-thirds of the patients who were followed for 3 years or more...
  7. pmc Histology of hereditary neuralgic amyotrophy
    N van Alfen
    Neuromuscular Centre Nijmegen, Institute of Neurology, 314 University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Neurol Neurosurg Psychiatry 76:445-7. 2005
    ....
  8. doi request reprint The influence of concentration/meditation on autonomic nervous system activity and the innate immune response: a case study
    Matthijs Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Psychosom Med 74:489-94. 2012
    ..The study participant holds several world records with regard to tolerating extreme cold and claims that he can influence his autonomic nervous system and thereby his innate immune response...
  9. doi request reprint Muscles alive: ultrasound detects fibrillations
    Sigrid Pillen
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Clin Neurophysiol 120:932-6. 2009
    ..In this study we investigated the ability of dynamic muscle ultrasound to detect fibrillations...
  10. doi request reprint Atypical dystonic shoulder movements following neuralgic amyotrophy
    William F Abdo
    Institute of Neurology and Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mov Disord 24:293-6. 2009
    ..The nature of the involuntary movements, which did not easily comply with classic descriptions of hyperkinetic movement disorders, is probably best referred to as dystonia...
  11. doi request reprint Detection of fibrillations using muscle ultrasound: diagnostic accuracy and identification of pitfalls
    Nens van Alfen
    Department of Neurology and Clinical Neurophysiology, Radboud University, Nijmegen Medical Center, Nijmegen, The Netherlands
    Muscle Nerve 43:178-82. 2011
    ..Ensuring a distal limb temperature of at least 34°C and identifying external movement artifacts as well as voluntary contractions can improve efficacy and open the way for diagnostic application of this technique...
  12. doi request reprint Sensory nerve conduction studies in neuralgic amyotrophy
    Nens van Alfen
    Department of Clinical Neurophysiology, Donders Center for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Am J Phys Med Rehabil 88:941-6. 2009
    ..Our findings also indicate that some sensory lesions may be in the nerve roots instead of the plexus. An examination of normal sensory nerve conduction studies does not preclude neuralgic amyotrophy as a diagnosis...
  13. ncbi request reprint The spectrum of polyneuropathies in childhood detected with electromyography
    George Shabo
    Department of Pediatric Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Pediatr Neurol 36:393-6. 2007
    ..Nerve biopsy nonetheless proved to have an important diagnostic yield in selected, complex cases...
  14. doi request reprint Quantitative muscle ultrasound and muscle force in healthy children: a 4-year follow-up study
    Joost Jacobs
    Department of Neurology and Clinical Neurophysiology 920, Donders Centre of Neuroscience, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500HB, Nijmegen, The Netherlands
    Muscle Nerve 47:856-63. 2013
    ..No longitudinal data on the normal development of muscle thickness (MT), quantitative muscle ultrasound echo intensity (EI), and muscle force (MF) in healthy children are yet available...
  15. doi request reprint Skeletal muscle ultrasound
    Sigrid Pillen
    Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Neurol Res 33:1016-24. 2011
    ..This opens the way to a broader use of muscle ultrasound in the diagnosis of peripheral nerve and muscle disorders...
  16. ncbi request reprint Neuromuscular involvement in various types of Ehlers-Danlos syndrome
    Nicol C Voermans
    Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Ann Neurol 65:687-97. 2009
    ..We designed a cross-sectional study to find out whether neuromuscular features are part of EDS...
  17. ncbi request reprint Pediatric median neuropathy due to pruritus in Alagille syndrome
    Nicol C Voermans
    Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Pediatr Neurol 35:216-9. 2006
    ..To our knowledge, median neuropathy has never been associated with Alagille syndrome, although severe pruritus is considered a major symptom and many patients exhibit widespread scratching and rubbing...
  18. doi request reprint Residual complaints after neuralgic amyotrophy
    Edith H Cup
    Department of Rehabilitation, Nijmegen Center for Evidence Based Practice, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Arch Phys Med Rehabil 94:67-73. 2013
    ....
  19. ncbi request reprint [An unusual cause of acute dyspnoea: neuralgic amyotrophy]
    Annenienke C van de Ven
    Universitair Medisch Centrum St Radboud, Nijmegen, The Netherlands
    Ned Tijdschr Geneeskd 153:A181. 2009
    ..Unfamiliarity with this condition may lead to severe delay in the diagnostic process and to unnecessary investigations, especially when no accompanying paresis of the shoulder girdle and arm musculature is present...
  20. ncbi request reprint Sural/radial nerve amplitude ratio: reference values in healthy subjects
    Berno U H Overbeek
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Center, The Netherlands
    Muscle Nerve 32:613-8. 2005
    ..Further study is needed to establish the clinical value of this SRAR in the early detection of axonal polyneuropathies...
  21. ncbi request reprint Peripheral nerve involvement in spinocerebellar ataxias
    Bart P C van de Warrenburg
    Department of Neurology, University Medical Center Nijmegen, The Netherlands
    Arch Neurol 61:257-61. 2004
    ....
  22. doi request reprint The assisted 6-minute cycling test to assess endurance in children with a neuromuscular disorder
    Merel Jansen
    Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
    Muscle Nerve 46:520-30. 2012
    ..We developed the assisted 6-minute cycling test (A6MCT) for the legs and arms and investigated its psychometric properties in healthy boys and boys with Duchenne muscular dystrophy (DMD)...
  23. doi request reprint Quantitative ultrasound of the tongue and submental muscles in children and young adults
    Lenie van den Engel-Hoek
    Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Department of Rehabilitation, PO Box 9101 or 818, 6500 HB Nijmegen, The Netherlands
    Muscle Nerve 46:31-7. 2012
    ..The data were compared with those of 5 patients with Duchenne muscular dystrophy (DMD)...
  24. doi request reprint Quantitative muscle ultrasound is a promising longitudinal follow-up tool in Duchenne muscular dystrophy
    Merel Jansen
    Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Department of Rehabilitation, Nijmegen, The Netherlands
    Neuromuscul Disord 22:306-17. 2012
    ..This increase was related to ambulatory status, functional grading, muscle strength and motor ability. Our study establishes QMUS as a practical and child-friendly tool for the longitudinal follow up of DMD patients...
  25. pmc Neuralgic amyotrophy and hepatitis E virus infection
    Jeroen J J van Eijk
    From the Department of Neurology J J J v E, N v A, B G M v E, Radboud University Nijmegen Medical Centre Department of Neurology J J J v E, Jeroen Bosch Hospital, Nijmegen, the Netherlands Cornwall Gastrointestinal Unit R G M, J G H, L B, L S, H R D, Clinical Microbiology R P B, V E, and Department of Neurology B M, Royal Cornwall Hospital Trust European Centre for the Environment and Human Health R G M, J G H, R P B, L B, H R D, University of Exeter Medical School, Truro, UK Centre for Infectious Disease Control J H J R, Division Virology, National Institute for Public Health and the Environment, Bilthoven Departments of Viroscience A A v d E, S D P, Immunology B C J, and Neurology B C J, Erasmus Medical Centre, University Medical Center Rotterdam, The Netherlands
    Neurology 82:498-503. 2014
    ....
  26. ncbi request reprint Efficacy of a combined physical and occupational therapy intervention in patients with subacute neuralgic amyotrophy: a pilot study
    Jos Ijspeert
    Department of Rehabilitation, Radboud University Medical Centre, Centre for Evidence Based Practice, Nijmegen, The Netherlands
    NeuroRehabilitation 33:657-65. 2013
    ..Many patients experience difficulties in performing activities of daily life and are unable to resume work. We developed a combined physical- and occupational therapy program for patients recovering from NA...
  27. pmc Endotoxemia-induced inflammation and the effect on the human brain
    Mark van den Boogaard
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500HB, The Netherlands
    Crit Care 14:R81. 2010
    ..Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described...
  28. doi request reprint Predictors of poor neurologic outcome in patients after cardiac arrest treated with hypothermia: a retrospective study
    Laurens L A Bisschops
    Department of Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Resuscitation 82:696-701. 2011
    ..We determined the effect of mild therapeutic hypothermia on the validity of the currently used clinical practice parameters...
  29. doi request reprint Muscle ultrasound: a grown-up technique for children with neuromuscular disorders
    Sigrid Pillen
    Muscle Nerve 38:1213-4. 2008