Research Topics
| Nens van AlfenSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
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Detail Information
Publications
Physical training in boys with Duchenne Muscular Dystrophy: the protocol of the No Use is Disuse studyMerel Jansen
Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, The Netherlands
BMC Pediatr 10:55. 2010..This paper describes the hypotheses and methods of the NUD study...
Clinical and pathophysiological concepts of neuralgic amyotrophyNens van Alfen
920 Clinical Neurophysiology, Department of Neurology, Radboud University Nijmegen Medical Center, Reinier Postlaan 4, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Nat Rev Neurol 7:315-22. 2011..This Review provides an overview of the current clinical and pathophysiological concepts and research topics in neuralgic amyotrophy...
Long-term pain, fatigue, and impairment in neuralgic amyotrophyNens van Alfen
Department of Neurology, Neuromuscular Centre Nijmegen, Donders Center for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Arch Phys Med Rehabil 90:435-9. 2009..Therefore, the objective of this study was to describe the prevalence of pain, psychologic symptoms, fatigue, functional status, and quality of life in patients with NA...
The neuralgic amyotrophy consultationNens van Alfen
Neurologist, clinical neurophysiologist, Neuromuscular Centre Nijmegen, Dept of Neurology and Clinical Neurophysiology, c o 920 KNF, Radboud University Nijmegen, Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
J Neurol 254:695-704. 2007..This article provides a practical overview of current knowledge on the clinical presentation, diagnosis, pathogenesis and the treatment of pain and complications...
The clinical spectrum of neuralgic amyotrophy in 246 casesNens van Alfen
Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Brain 129:438-50. 2006..5% in males), and their functional outcome was worse. Overall recovery was less favourable than usually assumed, with persisting pain and paresis in approximately two-thirds of the patients who were followed for 3 years or more...
Histology of hereditary neuralgic amyotrophyN van Alfen
Neuromuscular Centre Nijmegen, Institute of Neurology, 314 University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
J Neurol Neurosurg Psychiatry 76:445-7. 2005....
The influence of concentration/meditation on autonomic nervous system activity and the innate immune response: a case studyMatthijs Kox
Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Psychosom Med 74:489-94. 2012..The study participant holds several world records with regard to tolerating extreme cold and claims that he can influence his autonomic nervous system and thereby his innate immune response...
Atypical dystonic shoulder movements following neuralgic amyotrophyWilliam F Abdo
Institute of Neurology and Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Mov Disord 24:293-6. 2009..The nature of the involuntary movements, which did not easily comply with classic descriptions of hyperkinetic movement disorders, is probably best referred to as dystonia...
Muscles alive: ultrasound detects fibrillationsSigrid Pillen
Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Clin Neurophysiol 120:932-6. 2009..In this study we investigated the ability of dynamic muscle ultrasound to detect fibrillations...
Sensory nerve conduction studies in neuralgic amyotrophyNens van Alfen
Department of Clinical Neurophysiology, Donders Center for Neuroscience, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Am J Phys Med Rehabil 88:941-6. 2009..Our findings also indicate that some sensory lesions may be in the nerve roots instead of the plexus. An examination of normal sensory nerve conduction studies does not preclude neuralgic amyotrophy as a diagnosis...
The spectrum of polyneuropathies in childhood detected with electromyographyGeorge Shabo
Department of Pediatric Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Pediatr Neurol 36:393-6. 2007..Nerve biopsy nonetheless proved to have an important diagnostic yield in selected, complex cases...
Skeletal muscle ultrasoundSigrid Pillen
Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Neurol Res 33:1016-24. 2011..This opens the way to a broader use of muscle ultrasound in the diagnosis of peripheral nerve and muscle disorders...
Detection of fibrillations using muscle ultrasound: diagnostic accuracy and identification of pitfallsNens van Alfen
Department of Neurology and Clinical Neurophysiology, Radboud University, Nijmegen Medical Center, Nijmegen, The Netherlands
Muscle Nerve 43:178-82. 2011..Ensuring a distal limb temperature of at least 34°C and identifying external movement artifacts as well as voluntary contractions can improve efficacy and open the way for diagnostic application of this technique...
Neuromuscular involvement in various types of Ehlers-Danlos syndromeNicol C Voermans
Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Ann Neurol 65:687-97. 2009..We designed a cross-sectional study to find out whether neuromuscular features are part of EDS...
Pediatric median neuropathy due to pruritus in Alagille syndromeNicol C Voermans
Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Pediatr Neurol 35:216-9. 2006..To our knowledge, median neuropathy has never been associated with Alagille syndrome, although severe pruritus is considered a major symptom and many patients exhibit widespread scratching and rubbing...
Residual complaints after neuralgic amyotrophyEdith H Cup
Department of Rehabilitation, Nijmegen Center for Evidence Based Practice, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Arch Phys Med Rehabil 94:67-73. 2013....
[An unusual cause of acute dyspnoea: neuralgic amyotrophy]Annenienke C van de Ven
Universitair Medisch Centrum St Radboud, Nijmegen, The Netherlands
Ned Tijdschr Geneeskd 153:A181. 2009..Unfamiliarity with this condition may lead to severe delay in the diagnostic process and to unnecessary investigations, especially when no accompanying paresis of the shoulder girdle and arm musculature is present...
Sural/radial nerve amplitude ratio: reference values in healthy subjectsBerno U H Overbeek
Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Center, The Netherlands
Muscle Nerve 32:613-8. 2005..Further study is needed to establish the clinical value of this SRAR in the early detection of axonal polyneuropathies...
The assisted 6-minute cycling test to assess endurance in children with a neuromuscular disorderMerel Jansen
Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
Muscle Nerve 46:520-30. 2012..We developed the assisted 6-minute cycling test (A6MCT) for the legs and arms and investigated its psychometric properties in healthy boys and boys with Duchenne muscular dystrophy (DMD)...
Quantitative ultrasound of the tongue and submental muscles in children and young adultsLenie van den Engel-Hoek
Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Department of Rehabilitation, PO Box 9101 or 818, 6500 HB Nijmegen, The Netherlands
Muscle Nerve 46:31-7. 2012..The data were compared with those of 5 patients with Duchenne muscular dystrophy (DMD)...
Quantitative muscle ultrasound is a promising longitudinal follow-up tool in Duchenne muscular dystrophyMerel Jansen
Radboud University Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Department of Rehabilitation, Nijmegen, The Netherlands
Neuromuscul Disord 22:306-17. 2012..This increase was related to ambulatory status, functional grading, muscle strength and motor ability. Our study establishes QMUS as a practical and child-friendly tool for the longitudinal follow up of DMD patients...
Endotoxemia-induced inflammation and the effect on the human brainMark van den Boogaard
Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500HB, The Netherlands
Crit Care 14:R81. 2010..Effects of systemic inflammation on cerebral function are not clear, as both inflammation-induced encephalopathy as well as stress-hormone mediated alertness have been described...
Predictors of poor neurologic outcome in patients after cardiac arrest treated with hypothermia: a retrospective studyLaurens L A Bisschops
Department of Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Resuscitation 82:696-701. 2011..We determined the effect of mild therapeutic hypothermia on the validity of the currently used clinical practice parameters...
Peripheral nerve involvement in spinocerebellar ataxiasBart P C van de Warrenburg
Department of Neurology, University Medical Center Nijmegen, The Netherlands
Arch Neurol 61:257-61. 2004....
Muscle ultrasound: a grown-up technique for children with neuromuscular disordersSigrid Pillen
Muscle Nerve 38:1213-4. 2008
