Hedwig P van de Nieuwenhof

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. pmc Significant decrease of adenocarcinoma in situ not reflected in cervical adenocarcinoma incidence in the Netherlands 1989-2003
    H P van de Nieuwenhof
    Department of Gynaecology Obstetrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Br J Cancer 98:165-7. 2008
  2. pmc Hemoglobin level predicts outcome for vulvar cancer patients independent of GLUT-1 and CA-IX expression in tumor tissue
    Hedwig P van de Nieuwenhof
    Departments of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500, HB, Nijmegen, The Netherlands
    Virchows Arch 457:693-703. 2010
  3. doi request reprint The effect of vulvar lichen sclerosus on quality of life and sexual functioning
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, Netherlands
    J Psychosom Obstet Gynaecol 31:279-84. 2010
  4. doi request reprint Differentiated vulvar intraepithelial neoplasia is often found in lesions, previously diagnosed as lichen sclerosus, which have progressed to vulvar squamous cell carcinoma
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, The Netherlands
    Mod Pathol 24:297-305. 2011
  5. doi request reprint Never forget medication as a cause: vaginal ulceration caused by nicorandil
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Obstet Gynecol 201:e5-6. 2009
  6. doi request reprint Vulvar squamous cell carcinoma development after diagnosis of VIN increases with age
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynaecology 791, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Cancer 45:851-6. 2009
  7. doi request reprint First case of vaginal radical trachelectomy in a pregnant patient
    H P van de Nieuwenhof
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Gynecol Cancer 18:1381-5. 2008
  8. doi request reprint High levels of p53 expression correlate with DNA aneuploidy in (pre)malignancies of the vulva
    Irene A M van der Avoort
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Hum Pathol 41:1475-85. 2010
  9. doi request reprint The etiologic role of HPV in vulvar squamous cell carcinoma fine tuned
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Cancer Epidemiol Biomarkers Prev 18:2061-7. 2009
  10. doi request reprint The prognostic value of blood and lymph vessel parameters in lichen sclerosus for vulvar squamous cell carcinoma development: an immunohistochemical and electron microscopy study
    Irene A M van der Avoort
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Obstet Gynecol 203:167.e1-8. 2010

Collaborators

Detail Information

Publications13

  1. pmc Significant decrease of adenocarcinoma in situ not reflected in cervical adenocarcinoma incidence in the Netherlands 1989-2003
    H P van de Nieuwenhof
    Department of Gynaecology Obstetrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Br J Cancer 98:165-7. 2008
    ..008), mainly caused by adenocarcinoma in situ lesions with a concurrent squamous dysplasia...
  2. pmc Hemoglobin level predicts outcome for vulvar cancer patients independent of GLUT-1 and CA-IX expression in tumor tissue
    Hedwig P van de Nieuwenhof
    Departments of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500, HB, Nijmegen, The Netherlands
    Virchows Arch 457:693-703. 2010
    ..Because preoperative Hb levels inversely correlated with the number of comorbidic conditions and not with GLUT-1 or CA-IX expression, it is most likely that preoperative Hb levels represent overall physical condition...
  3. doi request reprint The effect of vulvar lichen sclerosus on quality of life and sexual functioning
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, Netherlands
    J Psychosom Obstet Gynaecol 31:279-84. 2010
    ..001). Patients who experienced more influence on their QoL had more sexual difficulties, leading to more sexual distress independent of their age...
  4. doi request reprint Differentiated vulvar intraepithelial neoplasia is often found in lesions, previously diagnosed as lichen sclerosus, which have progressed to vulvar squamous cell carcinoma
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, The Netherlands
    Mod Pathol 24:297-305. 2011
    ..Patients with lichen sclerosus with dyskeratosis and parakeratosis, hyperplasia and/or basal cellular atypia should be kept under close surveillance as these lesions also tend to progress to squamous cell carcinoma...
  5. doi request reprint Never forget medication as a cause: vaginal ulceration caused by nicorandil
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Obstet Gynecol 201:e5-6. 2009
    ..After a possible association was found with nicorandil therapy, this medication was stopped. Thereafter, the ulceration fully healed within 6 months...
  6. doi request reprint Vulvar squamous cell carcinoma development after diagnosis of VIN increases with age
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynaecology 791, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Cancer 45:851-6. 2009
    ....
  7. doi request reprint First case of vaginal radical trachelectomy in a pregnant patient
    H P van de Nieuwenhof
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Gynecol Cancer 18:1381-5. 2008
    ..Follow-up of 9 months is uneventful for both the mother and the child. The vaginal radical trachelectomy is a new approach in the treatment of cervical carcinoma during pregnancy...
  8. doi request reprint High levels of p53 expression correlate with DNA aneuploidy in (pre)malignancies of the vulva
    Irene A M van der Avoort
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Hum Pathol 41:1475-85. 2010
    ..Furthermore, high p53 expression correlates with increased DNA content and aneuploidy; but it requires further research to unveil a possible causal relation...
  9. doi request reprint The etiologic role of HPV in vulvar squamous cell carcinoma fine tuned
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Cancer Epidemiol Biomarkers Prev 18:2061-7. 2009
    ..This study was done to fine tune the role of high-risk HPV infection in vulvar squamous cell carcinoma development in relation to clinical prognosis...
  10. doi request reprint The prognostic value of blood and lymph vessel parameters in lichen sclerosus for vulvar squamous cell carcinoma development: an immunohistochemical and electron microscopy study
    Irene A M van der Avoort
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am J Obstet Gynecol 203:167.e1-8. 2010
    ..The objective of the study was to quantify vessel type and density in lichen sclerosus (LS) to find a marker for its malignant potential...
  11. doi request reprint A patient with lichen sclerosus, Langerhans cell histiocytosis, and invasive squamous cell carcinoma of the vulva
    Michiel Simons
    Department of Obstetrics and Gynecology, Catharina Hospital, Eindhoven, The Netherlands
    Am J Obstet Gynecol 203:e7-10. 2010
    ..In LCH, high amounts of non functional Langerhans cells are present in the affected tissue, making it possible that LCH may have contributed to vulvar cancer development in this patient...
  12. doi request reprint Specific intraepithelial localization of mast cells in differentiated vulvar intraepithelial neoplasia and its possible contribution to vulvar squamous cell carcinoma development
    Hedwig P van de Nieuwenhof
    Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Histopathology 57:351-62. 2010
    ....
  13. doi request reprint Does experience in colposcopy improve identification of high grade abnormalities?
    Ruud L Bekkers
    Department of Gynecology Obstetrics, Radboud University Nijmegen Medical Centre, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 141:75-8. 2008
    ..The sensitivity and positive predictive value (PPV) of colposcopy in identifying high grade intra-epithelial lesions (HSIL) performed by relatively inexperienced as compared to experienced colposcopists are evaluated...