Guido W M Swart

Summary

Affiliation: Radboud University
Country: The Netherlands

Publications

  1. ncbi Activated leukocyte cell adhesion molecule (CD166/ALCAM): developmental and mechanistic aspects of cell clustering and cell migration
    Guido W M Swart
    Department of Biochemistry, University of Nijmegen, The Netherlands
    Eur J Cell Biol 81:313-21. 2002
  2. pmc Cell 'guidling'
    Guido W M Swart
    Radboud University, Nijmegen, Netherlands
    EMBO Rep 7:348-51. 2006
  3. ncbi Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?
    Guido W M Swart
    Department of Biochemistry, Science Faculty, Radboud University Nijmegen, Nijmegen, Netherlands
    Cancer Metastasis Rev 24:223-36. 2005
  4. doi Modulation of activated leukocyte cell adhesion molecule-mediated invasion triggers an innate immune gene response in melanoma
    Jeroen W J van Kilsdonk
    Faculty of Science, Department of Biomolecular Chemistry, Radboud University Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 132:1462-70. 2012
  5. doi Keratinocytes drive melanoma invasion in a reconstructed skin model
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry, Faculty of Science, Radboud University, Nijmegen, The Netherlands
    Melanoma Res 20:372-80. 2010
  6. doi Soluble adhesion molecules in human cancers: sources and fates
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry, IMM and NCMLS, Faculty of Science, Radboud University Nijmegen, Nijmegen, The Netherlands
    Eur J Cell Biol 89:415-27. 2010
  7. ncbi Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity
    Pim C Lunter
    Department of Biochemistry 161, Nijmegen Center of Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
    Cancer Res 65:8801-8. 2005
  8. ncbi Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis
    Leon C L T van Kempen
    Department of Biochemistry NCMLS, University of Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 122:1293-301. 2004
  9. doi Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry 271, Institute for Molecules and Materials and Nijmegen Centre for Molecular Life Sciences, Faculty of Science, Radboud University Nijmegen
    Cancer Res 68:3671-9. 2008
  10. ncbi Multiple complementary transcripts of pCMa1, a novel gene located at chromosome 11p15.1-2, and melanocytic cell transformation
    Clifton B Meije
    Department of Biochemistry, University of Nijmegen, The Netherlands
    J Pathol 197:668-76. 2002

Collaborators

  • Helmut Burtscher
  • Claus Garbe
  • MEENHARD I HERLYN
  • W Westerhof
  • F Meier
  • Mikala Egeblad
  • Jeroen W J van Kilsdonk
  • Leon C L T van Kempen
  • Goos N P Van Muijen
  • Mieke Bergers
  • Clifton B Meije
  • Joost Schalkwijk
  • Pim C Lunter
  • Ulrich H Weidle
  • Wouter H Lamers
  • Theodorus B M Hakvoort
  • Pranab K Das
  • Ulrich Weidle
  • Mohamed R Daha
  • Jonathan Jarry
  • Nozomi Takahashi
  • Dirk J Ruiter
  • Roel H Wilting
  • Hanneke van Beek
  • Ine M H A Cornelissen
  • Peter H G M Willems
  • Monique J F Kersten-Niessen
  • Henri P J Bloemers
  • Allard C van der Wal
  • Chi Hau
  • Miranda M E Jans
  • Marielle Alders

Detail Information

Publications12

  1. ncbi Activated leukocyte cell adhesion molecule (CD166/ALCAM): developmental and mechanistic aspects of cell clustering and cell migration
    Guido W M Swart
    Department of Biochemistry, University of Nijmegen, The Netherlands
    Eur J Cell Biol 81:313-21. 2002
    ..Accumulating evidence suggests that ALCAM expression may reflect the onset of a cellular program for homeostatic control of growth saturation, which induces either growth arrest or cell migration when the upper limits are exceeded...
  2. pmc Cell 'guidling'
    Guido W M Swart
    Radboud University, Nijmegen, Netherlands
    EMBO Rep 7:348-51. 2006
  3. ncbi Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?
    Guido W M Swart
    Department of Biochemistry, Science Faculty, Radboud University Nijmegen, Nijmegen, Netherlands
    Cancer Metastasis Rev 24:223-36. 2005
    ..It is hypothesized that ALCAM may function as a cell surface sensor to register local growth saturation and to regulate cellular signaling and dynamic responses...
  4. doi Modulation of activated leukocyte cell adhesion molecule-mediated invasion triggers an innate immune gene response in melanoma
    Jeroen W J van Kilsdonk
    Faculty of Science, Department of Biomolecular Chemistry, Radboud University Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 132:1462-70. 2012
    ..Together, our results demonstrate a link between ALCAM functionality and the immune transcriptome, and support the assumption that ALCAM-ALCAM interactions could function as a cell signaling complex to promote melanoma tumor invasion...
  5. doi Keratinocytes drive melanoma invasion in a reconstructed skin model
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry, Faculty of Science, Radboud University, Nijmegen, The Netherlands
    Melanoma Res 20:372-80. 2010
    ....
  6. doi Soluble adhesion molecules in human cancers: sources and fates
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry, IMM and NCMLS, Faculty of Science, Radboud University Nijmegen, Nijmegen, The Netherlands
    Eur J Cell Biol 89:415-27. 2010
    ..Based on currently available data, released soluble adhesion molecules contribute to cancer progression and therefore should not be regarded as unrelated and non-functional side products of tumor progression...
  7. ncbi Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity
    Pim C Lunter
    Department of Biochemistry 161, Nijmegen Center of Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
    Cancer Res 65:8801-8. 2005
    ..These data attribute a novel signaling role to ALCAM in regulation of proteolysis and support its previously postulated sensor function in invasive growth...
  8. ncbi Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis
    Leon C L T van Kempen
    Department of Biochemistry NCMLS, University of Nijmegen, Nijmegen, The Netherlands
    J Invest Dermatol 122:1293-301. 2004
    ..ALCAM induction could, thus, provide an attractive target for proteolysis as a part of a more complex cellular program that couples growth and migration and facilitates dissemination...
  9. doi Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule
    Jeroen W J van Kilsdonk
    Department of Biomolecular Chemistry 271, Institute for Molecules and Materials and Nijmegen Centre for Molecular Life Sciences, Faculty of Science, Radboud University Nijmegen
    Cancer Res 68:3671-9. 2008
    ....
  10. ncbi Multiple complementary transcripts of pCMa1, a novel gene located at chromosome 11p15.1-2, and melanocytic cell transformation
    Clifton B Meije
    Department of Biochemistry, University of Nijmegen, The Netherlands
    J Pathol 197:668-76. 2002
    ....
  11. ncbi International Melanoma Research Congress--Foundation for Melanoma Research. 21-24 June 2003, Philadelphia, PA, USA
    Guido W M Swart
    161 Department of Biochemistry, Nijmegen Center for Molecular Life Sciences, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    IDrugs 6:752-4. 2003
  12. ncbi Gene expression patterns in melanocytic cells: candidate markers for early stage and malignant transformation
    Clifton B Meije
    Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    J Pathol 196:51-8. 2002
    ..The Ras-related protein Rab5b showed lower levels of expression in highly metastatic than in other melanoma cells. These three cDNAs may therefore be involved in the early stage and malignant transformation of melanocytes...