L M Staals

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. doi Multicentre, parallel-group, comparative trial evaluating the efficacy and safety of sugammadex in patients with end-stage renal failure or normal renal function
    L M Staals
    Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Br J Anaesth 101:492-7. 2008
  2. doi Reduced clearance of rocuronium and sugammadex in patients with severe to end-stage renal failure: a pharmacokinetic study
    L M Staals
    Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 104:31-9. 2010
  3. doi Train-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadex
    L M Staals
    Department of Anaesthesiology, Erasmus University Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Anaesthesiol Scand 55:700-7. 2011

Collaborators

Detail Information

Publications3

  1. doi Multicentre, parallel-group, comparative trial evaluating the efficacy and safety of sugammadex in patients with end-stage renal failure or normal renal function
    L M Staals
    Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Br J Anaesth 101:492-7. 2008
    ..As sugammadex is primarily cleared renally, this phase III trial investigated the efficacy and safety of sugammadex for reversal of rocuronium-induced neuromuscular block (NMB) in patients with end-stage renal failure...
  2. doi Reduced clearance of rocuronium and sugammadex in patients with severe to end-stage renal failure: a pharmacokinetic study
    L M Staals
    Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 104:31-9. 2010
    ..The sugammadex-rocuronium complex is eliminated by the kidneys. This trial investigated the pharmacokinetics (PKs) of sugammadex and rocuronium in patients with renal failure and healthy controls...
  3. doi Train-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadex
    L M Staals
    Department of Anaesthesiology, Erasmus University Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Anaesthesiol Scand 55:700-7. 2011
    ..9. The recovery time of T1 was not described. This retrospective investigation describes the recovery of T1 vs. TOF ratio after the reversal of NMB with sugammadex...