Arnt F A Schellekens

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. doi request reprint COMT Val158Met modulates the effect of childhood adverse experiences on the risk of alcohol dependence
    Arnt F A Schellekens
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, The Netherlands
    Addict Biol 18:344-56. 2013
  2. doi request reprint Early-onset alcohol dependence increases the acoustic startle reflex
    Arnt F A Schellekens
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Alcohol Clin Exp Res 36:1075-83. 2012
  3. doi request reprint Reduced dopamine receptor sensitivity as an intermediate phenotype in alcohol dependence and the role of the COMT Val158Met and DRD2 Taq1A genotypes
    Arnt F A Schellekens
    Donders Institute for Brain, Cognition, and Behaviour, Department of Psychiatry, Radboud University Nijmegen Medical Centre, The Netherlands
    Arch Gen Psychiatry 69:339-48. 2012
  4. doi request reprint The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls
    Arnt F A Schellekens
    Department of Psychiatry, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Eur Neuropsychopharmacol 19:68-73. 2009
  5. pmc Effect of apomorphine on cognitive performance and sensorimotor gating in humans
    Arnt F A Schellekens
    Department of Psychiatry, Radboud Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands
    Psychopharmacology (Berl) 207:559-69. 2010
  6. doi request reprint Alcohol dependence and anxiety increase error-related brain activity
    Arnt F A Schellekens
    Department of Psychiatry, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Addiction 105:1928-34. 2010
  7. pmc Anatomical connection strength predicts dopaminergic drug effects on fronto-striatal function
    Martine R van Schouwenburg
    Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, and Department of Psychiatry, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Psychopharmacology (Berl) 227:521-31. 2013

Collaborators

Detail Information

Publications7

  1. doi request reprint COMT Val158Met modulates the effect of childhood adverse experiences on the risk of alcohol dependence
    Arnt F A Schellekens
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, The Netherlands
    Addict Biol 18:344-56. 2013
    ..Exposed carriers of a low-activity Met allele have a higher risk to develop severe alcohol dependence than individuals homozygous for the Val allele...
  2. doi request reprint Early-onset alcohol dependence increases the acoustic startle reflex
    Arnt F A Schellekens
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Alcohol Clin Exp Res 36:1075-83. 2012
    ....
  3. doi request reprint Reduced dopamine receptor sensitivity as an intermediate phenotype in alcohol dependence and the role of the COMT Val158Met and DRD2 Taq1A genotypes
    Arnt F A Schellekens
    Donders Institute for Brain, Cognition, and Behaviour, Department of Psychiatry, Radboud University Nijmegen Medical Centre, The Netherlands
    Arch Gen Psychiatry 69:339-48. 2012
    ..The use of intermediate phenotypes may help make clear the mode of action of various candidate genes and improve the reproducibility of genetic association studies...
  4. doi request reprint The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls
    Arnt F A Schellekens
    Department of Psychiatry, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Eur Neuropsychopharmacol 19:68-73. 2009
    ..Little is known on functional changes in the fronto-striatal-thalamic dopaminergic neurocircuitry in these patients. The objective of this study was to assess sensitivity of prefrontal dopamine receptors in alcohol dependent patients...
  5. pmc Effect of apomorphine on cognitive performance and sensorimotor gating in humans
    Arnt F A Schellekens
    Department of Psychiatry, Radboud Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands
    Psychopharmacology (Berl) 207:559-69. 2010
    ..The objective of the current study was to assess dopamine receptor functioning at the forebrain level...
  6. doi request reprint Alcohol dependence and anxiety increase error-related brain activity
    Arnt F A Schellekens
    Department of Psychiatry, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Addiction 105:1928-34. 2010
    ..We expected decreased error monitoring in alcohol-dependent patients with impulse control disorders and increased error monitoring in anxious alcohol-dependent patients...
  7. pmc Anatomical connection strength predicts dopaminergic drug effects on fronto-striatal function
    Martine R van Schouwenburg
    Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, and Department of Psychiatry, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Psychopharmacology (Berl) 227:521-31. 2013
    ..However, there is a large variability in the direction and extent of dopaminergic drug effects across individuals...