- No increased risk of cancer after coal tar treatment in patients with psoriasis or eczemaJudith H J Roelofzen
Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
J Invest Dermatol 130:953-61. 2010..69-1.72). This study has sufficient power to show that coal tar treatment is not associated with an increased risk of cancer. These results indicate that coal tar can be maintained as a safe treatment in dermatological practice...
- DNA adducts in skin biopsies and 1-hydroxypyrene in urine of psoriasis patients and healthy volunteers following treatment with coal tarJ H J Roelofzen
Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Toxicol Lett 213:39-44. 2012..05). Biomarkers for uptake, bioavailability and bioactivation of PAH were lower in patients compared to volunteers. These data suggest a lower risk of carcinogenic effects of CTO in psoriatic skin compared to healthy skin...
- Coal tar in dermatologyJudith H J Roelofzen
Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
J Dermatolog Treat 18:329-34. 2007..New, well-designed, epidemiological studies are necessary to assess the risk of skin tumors and other malignancies after dermatological use of coal tar...