Calin Popa

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Ann Rheum Dis 66:1503-7. 2007
  2. ncbi Circulating leptin and adiponectin concentrations during tumor necrosis factor blockade in patients with active rheumatoid arthritis
    Calin Popa
    Department of Rheumatology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Rheumatol 36:724-30. 2009
  3. ncbi Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
    Shahla Abdollahi-Roodsaz
    Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arthritis Rheum 56:2957-67. 2007
  4. ncbi Cytokine production from stimulated whole blood cultures in rheumatoid arthritis patients treated with various TNF blocking agents
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Cytokine Netw 20:88-93. 2009
  5. ncbi The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Lipid Res 48:751-62. 2007
  6. ncbi Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis
    Leo A B Joosten
    Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Proc Natl Acad Sci U S A 105:9017-22. 2008
  7. ncbi TLR2 promotes Th2/Th17 responses via TLR4 and TLR7/8 by abrogating the type I IFN amplification loop
    Mark H Wenink
    Department of Rheumatology, Radboud University Nijmegen Medical Center, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands
    J Immunol 183:6960-70. 2009
  8. ncbi MIF production by dendritic cells is differentially regulated by Toll-like receptors and increased during rheumatoid arthritis
    Calin Popa
    Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Cytokine 36:51-6. 2006
  9. ncbi [Reimbursement for alternative medical treatment in the Netherlands, incomprehensible]
    Martijn W F van den Hoogen
    Universitair Medisch Centrum St Radboud, afd Interne Geneeskunde, Nijmegen, The Netherlands
    Ned Tijdschr Geneeskd 156:A4227. 2012
  10. ncbi Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, The Netherlands
    Infect Immun 75:4831-7. 2007

Collaborators

Detail Information

Publications14

  1. ncbi Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Ann Rheum Dis 66:1503-7. 2007
    ..In the present study, we investigated the effects of 1-year therapy with anti-TNF on the lipid profile of RA patients...
  2. ncbi Circulating leptin and adiponectin concentrations during tumor necrosis factor blockade in patients with active rheumatoid arthritis
    Calin Popa
    Department of Rheumatology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Rheumatol 36:724-30. 2009
    ..We investigated the effects of longterm therapeutic tumor necrosis factor (TNF) blockade on adipocytokine concentrations in patients with RA...
  3. ncbi Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
    Shahla Abdollahi-Roodsaz
    Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arthritis Rheum 56:2957-67. 2007
    ..The objective of this study was to investigate the involvement of TLR-4 activation in the development and progression of autoimmune destructive arthritis...
  4. ncbi Cytokine production from stimulated whole blood cultures in rheumatoid arthritis patients treated with various TNF blocking agents
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Cytokine Netw 20:88-93. 2009
    ..As a possible mechanism contributing to that, we assessed the modulation of cytokine production induced by TNF neutralization...
  5. ncbi The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Lipid Res 48:751-62. 2007
    ..Current investigations assessing the impact of anti-TNF agents on intermediary metabolism suggest that TNF-alpha blockade may improve insulin resistance and lipid profiles in patients with chronic inflammatory diseases...
  6. ncbi Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis
    Leo A B Joosten
    Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Proc Natl Acad Sci U S A 105:9017-22. 2008
    ..Whether a distorted balance between the function of Nod1 and/or Nod2 is involved in the pathogenesis of human autoinflammatory or autoimmune disease, such as rheumatoid arthritis, remains to be elucidated...
  7. ncbi TLR2 promotes Th2/Th17 responses via TLR4 and TLR7/8 by abrogating the type I IFN amplification loop
    Mark H Wenink
    Department of Rheumatology, Radboud University Nijmegen Medical Center, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands
    J Immunol 183:6960-70. 2009
    ..This shift in T cell responses was inherent to the inability of TLR2-stimulated DCs to produce IL-12p70 and was dependent on the production of IL-1 and IL-6...
  8. ncbi MIF production by dendritic cells is differentially regulated by Toll-like receptors and increased during rheumatoid arthritis
    Calin Popa
    Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Cytokine 36:51-6. 2006
    ..The secretion of MIF by dendritic cells is differentially regulated by TLRs. In addition, TNF-alpha, RANKL, and CD40L augment MIF production by DCs and thus play a potential role in the amplification of the inflammatory loop in RA...
  9. ncbi [Reimbursement for alternative medical treatment in the Netherlands, incomprehensible]
    Martijn W F van den Hoogen
    Universitair Medisch Centrum St Radboud, afd Interne Geneeskunde, Nijmegen, The Netherlands
    Ned Tijdschr Geneeskd 156:A4227. 2012
    ..Reimbursement for these therapies is made at the expense of other effective and proven treatments. This can be changed through the concerted efforts of policy-makers, doctors, the IGZ, and health insurance companies...
  10. ncbi Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4
    Calin Popa
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, The Netherlands
    Infect Immun 75:4831-7. 2007
    ..Because of the role of TLR4 in inflammation, B. quintana LPS may prove useful as a potent anti-TLR4 agent with therapeutic potential in both infections and autoimmune inflammation...
  11. ncbi Improved insulin sensitivity by anti-TNFalpha antibody treatment in patients with rheumatic diseases
    Frank C Huvers
    Ann Rheum Dis 66:558-9. 2007
  12. ncbi Anti-TNF therapy and plasma HDL cholesterol concentration
    Calin Popa
    Atherosclerosis 182:375; author reply 377. 2005
  13. ncbi Cytokine production of stimulated whole blood cultures in rheumatoid arthritis patients receiving short-term infliximab therapy
    Calin Popa
    Department of Internal Medicine, University Medical Center St. Radboud, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
    Cytokine 30:72-7. 2005
    ....
  14. ncbi Circulating CXCL16 is not related to circulating oxLDL in patients with rheumatoid arthritis
    Antoine W T van Lieshout
    Department of Rheumatology, Radboud University Nijmegen Medical Centre and Nijmegen Centre of Molecular Life Sciences, The Netherlands
    Biochem Biophys Res Commun 355:392-7. 2007
    ..These data suggest that binding of oxLDL by soluble CXCL16 does not play a role in atherosclerosis and, although confirmation in larger studies is needed, that circulating CXCL16 is not related to the presence of CVD in patients with RA...