Theo A Peters

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint Changes in ultrastructural characteristics of endolymphatic sac ribosome-rich cells of the rat during development
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center St Radboud, Philips van Leydenlaan 15, 6500 HB Nijmegen, The Netherlands
    Hear Res 176:94-104. 2003
  2. ncbi request reprint Genetic disorders of transporters/channels in the inner ear and their relation to the kidney
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center Nijmegen, Philips van Leydenlaan 15, 6525 EX Nijmegen, The Netherlands
    Pediatr Nephrol 19:1194-201. 2004
  3. ncbi request reprint No evidence of hearing loss in pseudohypoaldosteronism type 1 patients
    Theo A Peters
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Otolaryngol 126:237-9. 2006
  4. doi request reprint The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase
    Karlien L M Coene
    Department of Human Genetics 855, Radboud University Nijmegen Medical Centre, PO Box9101, 6500 HB Nijmegen, The Netherlands
    Hum Mol Genet 20:3592-605. 2011
  5. doi request reprint Association of whirlin with Cav1.3 (alpha1D) channels in photoreceptors, defining a novel member of the usher protein network
    Ferry F J Kersten
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Invest Ophthalmol Vis Sci 51:2338-46. 2010
  6. ncbi request reprint Differences in endolymphatic sac mitochondria-rich cells indicate specific functions
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center St Radboud, Nijmegen, The Netherlands
    Laryngoscope 112:534-41. 2002
  7. pmc Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein
    Erwin Van Wijk
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Hum Mol Genet 18:51-64. 2009
  8. pmc Mutations in RAB28, encoding a farnesylated small GTPase, are associated with autosomal-recessive cone-rod dystrophy
    Susanne Roosing
    Department of Human Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands
    Am J Hum Genet 93:110-7. 2013
  9. pmc The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically
    Ferry Fj Kersten
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Cilia 1:2. 2012
  10. doi request reprint Neurofilament localization and phosphorylation in the developing inner ear of the rat
    Edith L G M Tonnaer
    Radboud University Nijmegen Medical Center, Department of Otorhinolaryngology, Head and Neck Surgery, Donders Institute for Brain, Cognition and Behaviour, Center for Neuroscience, Philips van Leydenlaan 15, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Hear Res 267:27-35. 2010

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Changes in ultrastructural characteristics of endolymphatic sac ribosome-rich cells of the rat during development
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center St Radboud, Philips van Leydenlaan 15, 6500 HB Nijmegen, The Netherlands
    Hear Res 176:94-104. 2003
    ....
  2. ncbi request reprint Genetic disorders of transporters/channels in the inner ear and their relation to the kidney
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center Nijmegen, Philips van Leydenlaan 15, 6525 EX Nijmegen, The Netherlands
    Pediatr Nephrol 19:1194-201. 2004
    ..Based on data from human disorders (with or without mouse counterparts) and mouse models (without human counterparts) this article focuses on the involvement of these transporters/channels in hearing loss...
  3. ncbi request reprint No evidence of hearing loss in pseudohypoaldosteronism type 1 patients
    Theo A Peters
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Otolaryngol 126:237-9. 2006
    ....
  4. doi request reprint The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase
    Karlien L M Coene
    Department of Human Genetics 855, Radboud University Nijmegen Medical Centre, PO Box9101, 6500 HB Nijmegen, The Netherlands
    Hum Mol Genet 20:3592-605. 2011
    ..Our data are in line with previously established roles in the cilium of other members of the Nek protein family and define NEK4 as a ciliopathy candidate gene...
  5. doi request reprint Association of whirlin with Cav1.3 (alpha1D) channels in photoreceptors, defining a novel member of the usher protein network
    Ferry F J Kersten
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Invest Ophthalmol Vis Sci 51:2338-46. 2010
    ..This study was undertaken to identify novel, Usher syndrome-associated, interacting partners of whirlin and thereby obtain more insights into the function of whirlin...
  6. ncbi request reprint Differences in endolymphatic sac mitochondria-rich cells indicate specific functions
    Theo A Peters
    Department of Otorhinolaryngology, University Medical Center St Radboud, Nijmegen, The Netherlands
    Laryngoscope 112:534-41. 2002
    ..The purpose of the study was to examine the specific involvement of endolymphatic sac mitochondria-rich cells in endolymph homeostasis...
  7. pmc Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein
    Erwin Van Wijk
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Hum Mol Genet 18:51-64. 2009
    ..The direct association of Nlp(isoB) with USH2A(isoB) and lebercilin indicates that Nlp can be considered as a novel candidate gene for USH, LCA and allied retinal ciliopathies...
  8. pmc Mutations in RAB28, encoding a farnesylated small GTPase, are associated with autosomal-recessive cone-rod dystrophy
    Susanne Roosing
    Department of Human Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands
    Am J Hum Genet 93:110-7. 2013
    ..This study reveals a crucial role for RAB28 in photoreceptor function and suggests that mutations in other Rab proteins may also be associated with retinal dystrophies...
  9. pmc The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically
    Ferry Fj Kersten
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Cilia 1:2. 2012
    ..abstract:..
  10. doi request reprint Neurofilament localization and phosphorylation in the developing inner ear of the rat
    Edith L G M Tonnaer
    Radboud University Nijmegen Medical Center, Department of Otorhinolaryngology, Head and Neck Surgery, Donders Institute for Brain, Cognition and Behaviour, Center for Neuroscience, Philips van Leydenlaan 15, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Hear Res 267:27-35. 2010
    ..The sequential pattern of neurofilament expression we describe may help understand the consequences of certain mutations, and contribute to develop therapeutic strategies...
  11. pmc Unexpected CEP290 mRNA splicing in a humanized knock-in mouse model for Leber congenital amaurosis
    Alejandro Garanto
    Department of Human Genetics, Radboud University Medical Centre, Nijmegen, The Netherlands Institute for Genetic and Metabolic Disease, Radboud University Medical Centre, Nijmegen, The Netherlands
    PLoS ONE 8:e79369. 2013
    ..Together, our results show clear differences in the recognition of splice sites between mice and humans, and emphasize that care is warranted when generating animal models for human genetic diseases caused by splice mutations. ..
  12. ncbi request reprint Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome
    Heleen H Arts
    Department of Human Genetics, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands
    Nat Genet 39:882-8. 2007
    ..This work identifies RPGRIP1L as a gene responsible for JBTS and establishes a central role for cilia and basal bodies in the pathophysiology of this disorder...
  13. pmc Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics
    Bart M G Smits
    Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands
    Genetics 170:1887-96. 2005
    ..In addition, we demonstrate proof of principle for the generation and cloning of human disease models in rat using ENU mutagenesis, providing good perspectives for systematic phenotypic screens in the rat...