Research Topics
| Rocus R KlontSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
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Detail Information
Publications
Utility of Aspergillus antigen detection in specimens other than serum specimensRocus R Klont
Department of Medical Microbiology, University Medical Center St Radboud, Nijmegen, The Netherlands
Clin Infect Dis 39:1467-74. 2004..Clearly, well-designed prospective studies with systematic sampling and use of consensus case definitions are needed to compare the performance of antigen detection in samples other than serum specimens with that in serum specimens...
Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazoleRocus R Klont
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Clin Infect Dis 40:e110-2. 2005..Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160% of the plasma drug level)...
Legionella pneumophila in commercial bottled mineral waterRocus R Klont
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
FEMS Immunol Med Microbiol 47:42-4. 2006..pneumophila cells as well. Whether VBNC bacteria may be present in bottled mineral waters and the risk for infection this may pose for severely immunocompromised patients should be investigated...
Paradoxical increase in circulating Aspergillus antigen during treatment with caspofungin in a patient with pulmonary aspergillosisRocus R Klont
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Clin Infect Dis 43:e23-5. 2006..With the exception of treatment with the echinocandin, no other factors were found that might explain this clinical observation, which was supported by experiments done in vitro...
Improved detection of circulating Aspergillus antigen by use of a modified pretreatment procedureMonique A S H Mennink-Kersten
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 HB Nijmegen, The Netherlands
J Clin Microbiol 46:1391-7. 2008..The 10-fold concentration step increased the GMI as high as 121-fold. The MT resulted not only in positive reactivity in samples that tested negative with the CT but also in the earlier detection of antigen by 2 to 17 days...
Bifidobacterial lipoglycan as a new cause for false-positive platelia Aspergillus enzyme-linked immunosorbent assay reactivityMonique A S H Mennink-Kersten
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 HB Nijmegen, The Netherlands
J Clin Microbiol 43:3925-31. 2005..Since high concentrations of bifidobacteria are present in the human gut, these bacteria or excreted lipoglycan may cause false serum PA ELISA reactivity in selected patient groups, especially neonates...
Bifidobacterium lipoteichoic acid and false ELISA reactivity in aspergillus antigen detectionMonique A S H Mennink-Kersten
Department of Medical Microbiology, University Medical Centre Nijmegen, Netherland
Lancet 363:325-7. 2004..If our hypothesis is correct, we might find a method to discriminate between false-positive and true-positive ELISA results and thereby prevent unnecessary pre-emptive treatment of patients...
Validating PCR for detecting invasive aspergillosisPaul E Verweij
Br J Haematol 127:235-6. 2004
