Bert U Kleine

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint Interspike interval analysis in a patient with peripheral nerve hyperexcitability and potassium channel antibodies
    Bert U Kleine
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500HB Nijmegen, The Netherlands
    Muscle Nerve 37:269-74. 2008
  2. doi request reprint Prospective, blind study of the triple stimulation technique in the diagnosis of ALS
    Bert U Kleine
    Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Clinical Neurophysiology, Nijmegen, The Netherlands
    Amyotroph Lateral Scler 11:67-75. 2010
  3. doi request reprint Firing pattern of fasciculations in ALS: evidence for axonal and neuronal origin
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500HB Nijmegen, The Netherlands
    Neurology 70:353-9. 2008
  4. ncbi request reprint Inter-operator agreement in decomposition of motor unit firings from high-density surface EMG
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Electromyogr Kinesiol 18:652-61. 2008
  5. doi request reprint Fasciculations and their F-response revisited: high-density surface EMG in ALS and benign fasciculations
    Bert U Kleine
    Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Neurophysiol 123:399-405. 2012
  6. ncbi request reprint Using two-dimensional spatial information in decomposition of surface EMG signals
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Center, PO Box 9101, 6500HB Nijmegen, The Netherlands
    J Electromyogr Kinesiol 17:535-48. 2007
  7. ncbi request reprint Fasciculation potentials in high-density surface EMG
    Gea Drost
    Institute of Neurology, Department of Clinical Neurophysiology, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Clin Neurophysiol 24:301-7. 2007
  8. doi request reprint Muscle ultrasonography: a diagnostic tool for amyotrophic lateral sclerosis
    Ilse M P Arts
    Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Neurophysiol 123:1662-7. 2012
  9. doi request reprint Muscle imaging: mapping responses to transcranial magnetic stimulation with high-density surface electromyography
    Gijs van Elswijk
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Cortex 44:609-16. 2008
  10. doi request reprint The alpha-motoneuron pool as transmitter of rhythmicities in cortical motor drive
    Dick F Stegeman
    Centre for Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Department of Neurology Clinical Neurophysiology, Nijmegen, The Netherlands
    Clin Neurophysiol 121:1633-42. 2010

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Interspike interval analysis in a patient with peripheral nerve hyperexcitability and potassium channel antibodies
    Bert U Kleine
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500HB Nijmegen, The Netherlands
    Muscle Nerve 37:269-74. 2008
    ..We conclude that ISI analysis is a useful tool to understand the membrane dynamics underlying abnormal motor unit activity...
  2. doi request reprint Prospective, blind study of the triple stimulation technique in the diagnosis of ALS
    Bert U Kleine
    Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Clinical Neurophysiology, Nijmegen, The Netherlands
    Amyotroph Lateral Scler 11:67-75. 2010
    ..To evaluate the diagnostic yield of magnetic cortical stimulation with the triple stimulation technique (TST) to identify upper motor neuron (UMN) involvement in patients suspected of having ALS...
  3. doi request reprint Firing pattern of fasciculations in ALS: evidence for axonal and neuronal origin
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500HB Nijmegen, The Netherlands
    Neurology 70:353-9. 2008
    ..We hypothesized that the discharge pattern of fasciculation potentials (FPs) would be different for FPs arising in the motor axon or in the spinal motor neuron...
  4. ncbi request reprint Inter-operator agreement in decomposition of motor unit firings from high-density surface EMG
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Electromyogr Kinesiol 18:652-61. 2008
    ..It was concluded that when full decomposition is achieved, two independent operators are likely to arrive at nearly identical firing patterns...
  5. doi request reprint Fasciculations and their F-response revisited: high-density surface EMG in ALS and benign fasciculations
    Bert U Kleine
    Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Neurophysiol 123:399-405. 2012
    ..To compare the prevalence of fasciculation potentials (FPs) with F-responses between patients with amyotrophic lateral sclerosis (ALS) and patients with benign fasciculations...
  6. ncbi request reprint Using two-dimensional spatial information in decomposition of surface EMG signals
    Bert U Kleine
    Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Center, PO Box 9101, 6500HB Nijmegen, The Netherlands
    J Electromyogr Kinesiol 17:535-48. 2007
    ..However, to detect the firing events of the MUs with a high accuracy, as needed for instance for estimation of firing synchrony, two-dimensional information from the complete grid electrode appears essential...
  7. ncbi request reprint Fasciculation potentials in high-density surface EMG
    Gea Drost
    Institute of Neurology, Department of Clinical Neurophysiology, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Clin Neurophysiol 24:301-7. 2007
    ..It allows long stable recording times and provides quantitative information. This electrophysiologic tool is expected to expand the existing knowledge of FP properties...
  8. doi request reprint Muscle ultrasonography: a diagnostic tool for amyotrophic lateral sclerosis
    Ilse M P Arts
    Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Neurophysiol 123:1662-7. 2012
    ..Furthermore, we assessed the ability of ultrasonography to identify subclinical lower motor neuron involvement...
  9. doi request reprint Muscle imaging: mapping responses to transcranial magnetic stimulation with high-density surface electromyography
    Gijs van Elswijk
    Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Cortex 44:609-16. 2008
    ..It however remains essential to use stimulus intensities as low as possible, to minimize the contribution of surrounding non-target muscles to the MEP...
  10. doi request reprint The alpha-motoneuron pool as transmitter of rhythmicities in cortical motor drive
    Dick F Stegeman
    Centre for Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Department of Neurology Clinical Neurophysiology, Nijmegen, The Netherlands
    Clin Neurophysiol 121:1633-42. 2010
    ..Investigate the effectiveness and frequency dependence of central drive transmission via the alpha-motoneuron pool to the muscle...
  11. doi request reprint Prevalence and distribution of fasciculations in healthy adults: Effect of age, caffeine consumption and exercise
    Jiske Fermont
    Neuromuscular Centre Nijmegen, Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University, The Netherlands
    Amyotroph Lateral Scler 11:181-6. 2010
    ..However, strenuous physical exercise caused a temporary increase in fasciculations, but only in lower leg muscles. Fasciculations above the knee should raise suspicion and may warrant further investigation...
  12. doi request reprint Sensitivity and specificity of the 'Awaji' electrodiagnostic criteria for amyotrophic lateral sclerosis: retrospective comparison of the Awaji and revised El Escorial criteria for ALS
    Werner A Boekestein
    Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Amyotroph Lateral Scler 11:497-501. 2010
    ..However, this diagnostic improvement appears eliminated if patients with probable laboratory-supported ALS - due to UMN signs in one region - should be categorized as possible ALS...
  13. ncbi request reprint Expectancy induces dynamic modulation of corticospinal excitability
    Gijs van Elswijk
    Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Cogn Neurosci 19:121-31. 2007
    ..Changes in corticospinal synchronization or other mechanisms involving spinal circuits are candidates mediating the modulation of corticospinal excitability by expectancy...
  14. ncbi request reprint Surface EMG: how far can you go?
    Machiel J Zwarts
    Department of Clinical Neurophysiology, Institute of Neurology, University Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands
    Suppl Clin Neurophysiol 57:111-9. 2004
  15. ncbi request reprint Multi-channel EMG of the M. triceps brachii in rats during treadmill locomotion
    Nikolaus P Schumann
    Motor Research Group, Institute of Pathophysiology, Friedrich Schiller University Jena, Erfurter Strasse 35, Germany
    Clin Neurophysiol 113:1142-51. 2002
    ....
  16. ncbi request reprint Stimulating motor wisdom
    Bert U Kleine
    J Appl Physiol 102:1737-8. 2007
  17. ncbi request reprint Bridging function and structure of the neuromuscular system
    Dick F Stegeman
    Clin Neurophysiol 117:1169-72. 2006
  18. ncbi request reprint Measuring the cortical silent period can increase diagnostic confidence for amyotrophic lateral sclerosis
    H Jurgen Schelhaas
    Department of Neurology, University Medical Centre Nijmegen, The Netherlands
    Amyotroph Lateral Scler 8:16-9. 2007
    ..83, specificity 0.56 (males) and sensitivity 0.81, specificity 0.82 (females). A CSP longer than the mentioned cut-off values should alarm the clinician for the presence of a disorder other than ALS...