Research Topics
| G J HengstmanSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
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Detail Information
Publications
Sensorimotor axonal polyneuropathy without hepatic failure in erythropoietic protoporphyriaGerald J D Hengstman
Department of Neurology, Catharina Hospital, Eindhoven, The Netherlands
J Clin Neuromuscul Dis 11:72-6. 2009..The presented case expands the forms of neurologic complications that can be seen in this specific form of porphyria...
Myositis specific autoantibodies: changing insights in pathophysiology and clinical associationsGerald J D Hengstman
Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, Internal mail number 326, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Curr Opin Rheumatol 16:692-9. 2004..Several studies have shown that MSAs are associated with specific clinical characteristics and can aid our understanding of the pathophysiology of myositis...
Delayed cranial neuropathy after neurosurgery caused by herpes simplex virus reactivation: report of three casesGerald J D Hengstman
Department of Neurology, University Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands
Surg Neurol 64:67-9; discussion 69-70. 2005..Delayed cranial neuropathy is an uncommon complication of neurosurgical interventions of which the exact etiology is uncertain. Several authors have hypothesized that reactivation of herpesviruses may play a role...
Treatment of dermatomyositis and polymyositis with anti-tumor necrosis factor-alpha: long-term follow-upG J D Hengstman
Neuromuscular Center Nijmegen, Institute of Neurology, University Medical Center Nijmegen, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands
Eur Neurol 52:61-3. 2004
Auditory dysfunction in chronic inflammatory demyelinating polyradiculoneuropathyGerald J D Hengstman
Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, The Netherlands
Neurology 62:1446-8. 2004
Clinical characteristics of patients with myositis and autoantibodies to different fragments of the Mi-2 beta antigenG J D Hengstman
Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, PO Box 9101, Internal Code 935, 6500 HB Nijmegen, The Netherlands
Ann Rheum Dis 65:242-5. 2006..To assess the clinical implications of autoantibodies directed against different parts of the Mi-2 beta autoantigen in patients with myositis...
[The anti-synthetase syndrome: muscle disease and multisystem disorder at the same time]G J Hengstman
Neuromusculair Centrum Nijmegen, Instituut voor Neurologie, Universitair Medisch Centrum St Radboud, Postbus 9101, 6500 HB Nijmegen
Ned Tijdschr Geneeskd 147:1485-9. 2003..The patients were treated with immunosuppressive therapy (azathioprine, prednisone, methotrexate) and recovered considerably...
Anti-signal recognition particle autoantibodies: marker of a necrotising myopathyG J D Hengstman
Department of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Ann Rheum Dis 65:1635-8. 2006..To elucidate the clinical importance of the anti-signal recognition particle (SRP) autoantibody in patients with myositis...
Successful treatment of dermatomyositis and polymyositis with anti-tumor-necrosis-factor-alpha: preliminary observationsG J D Hengstman
Neuromuscular Centre Nijmegen, Institute of Neurology, University Medical Centre Nijmegen, Nijmegen, The Netherlands
Eur Neurol 50:10-5. 2003..These preliminary results suggest that anti-TNF-alpha treatment with infliximab is a safe and rapidly effective therapy for myositis...
Neuromyelitis optica with clinical and histopathological involvement of the brainG J D Hengstman
Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Mult Scler 13:679-82. 2007..This is the first case that clearly shows that in NMO, the histopathology of the brain lesions is identical to that of the lesions in the optic nerves and spinal cord...
Open-label trial of anti-TNF-alpha in dermato- and polymyositis treated concomitantly with methotrexateG J D Hengstman
Neuromuscular Centre Nijmegen, Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Eur Neurol 59:159-63. 2008..To determine the efficacy of infliximab combined with weekly methotrexate in drug-naive recent-onset dermatomyositis and polymyositis...
High specificity of myositis specific autoantibodies for myositis compared with other neuromuscular disordersG J D Hengstman
Neuromuscular Centre Nijmegen, Dept of Neurology, University Medical Centre Nijmegen, 9101, 6500 HB, Nijmegen, The Netherlands
J Neurol 252:534-7. 2005..None of the FSHD patients tested positive. We conclude that the tested MSAs are highly specific for myositis and that they are not merely associated with muscle inflammation...
Myositis-specific autoantibodies: overview and recent developmentsG J Hengstman
Neuromuscular Centre Nijmegen, Institute of Neurology, University Medical Centre Nijmegen, Nijmegen, The Netherlands
Curr Opin Rheumatol 13:476-82. 2001..In this review, an overview is given of the various MSAs, their biochemical background, their clinical usefulness, and the promises they hold for a better understanding of IIM...
Autoantibody profiles in the sera of European patients with myositisR Brouwer
Department of Biochemistry, University of Nijmegen, Nijmegen, The Netherlands
Ann Rheum Dis 60:116-23. 2001..Furthermore, our data show that some sera may contain more than one type of MSA and confirm the strong association of anti-Ro52 with anti-Jo-1 reactivity...
Polymyositis: an overdiagnosed entityGerald J D Hengstman
Neurology 63:402-3; author reply 403. 2004
Concomitant dermatomyositis and myasthenia gravis presenting with respiratory insufficiencyBart P C van de Warrenburg
Department of Neurology, University Medical Center St Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Muscle Nerve 25:293-6. 2002..The distinguishing clinical, electrophysiological, and biopsy findings are discussed. We suggest that an underlying immunoregulatory disorder was present, explaining the occurrence of three rare immune-mediated diseases in one patient...
Muscle-fiber conduction velocity and electromyography as diagnostic tools in patients with suspected inflammatory myopathy: a prospective studyPaul J Blijham
Department of Clinical Neurophysiology, Institute of Neurology, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Muscle Nerve 29:46-50. 2004..We conclude that the utility of electrodiagnostic examination can be increased if EMG examination is combined with MFCV studies...
Autoantibodies directed to novel components of the PM/Scl complex, the human exosomeRick Brouwer
Department of Biochemistry, University of Nijmegen, NL 6500 HB Nijmegen, The Netherlands
Arthritis Res 4:134-8. 2002..These results further support the conception that the autoimmune response may initially be directed to PM/Scl-100, whereas intermolecular epitope spreading may have caused the autoantibody response directed to the associated components...
Needle electromyographic findings in 98 patients with myositisPaul J Blijham
Department of Clinical Neurophysiology, Institute of Neurology, Institute of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Eur Neurol 55:183-8. 2006..These results illustrate the spectrum of EMG findings in myositis, and may aid the clinician in the interpretation of the EMG in these patients...
Advances in the immunopathophysiology of the idiopathic inflammatory myopathies: not as simple as suspectedGerald J D Hengstman
Department of Neurology, Maxima Medical Centre, Eindhoven, The Netherlands
Curr Rheumatol Rep 9:280-5. 2007..This article discusses the most important developments and their methodologic short-comings...
Magnetic resonance imaging criteria to differentiate inclusion body myositis from polymyositisGerald J D Hengstman
J Rheumatol 30:1892. 2003
Persistent increased risk for thymoma in myasthenia gravis associated with myositisGerald J D Hengstman
Muscle Nerve 34:251-2. 2006
Bilateral ocular myositis as a late complication of dermatomyositisGerald J D Hengstman
J Rheumatol 32:2498; author reply 2499-500. 2005
Polymyositis, invasion of non-necrotic muscle fibres, and the art of repetitionGerald J D Hengstman
Neuromuscular Centre Nijmegen, Department of Neurology, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, Netherlands
BMJ 329:1464-7. 2004
