Uta Flucke

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. doi request reprint Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Histopathology 62:925-30. 2013
  2. doi request reprint EWSR1 gene rearrangement occurs in a subset of cutaneous myoepithelial tumors: a study of 18 cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mod Pathol 24:1444-50. 2011
  3. doi request reprint EWSR1-ATF1 chimeric transcript in a myoepithelial tumor of soft tissue: a case report
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Hum Pathol 43:764-8. 2012
  4. pmc NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 Nijmegen, The Netherlands
    Virchows Arch 460:621-8. 2012
  5. pmc Fibrous dysplasia of bone associated with soft-tissue myxomas as well as an intra-osseous myxoma in a woman with Mazabraud's syndrome: a case report
    Wybren A van der Wal
    Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Postbox 9101, NL 6500 HB Nijmegen, The Netherlands
    J Med Case Reports 5:239. 2011
  6. doi request reprint Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mod Pathol 24:82-9. 2011
  7. doi request reprint Myxoid epithelioid sarcoma: a diagnostic challenge. A report on six cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Histopathology 57:753-9. 2010
  8. ncbi request reprint SMARCB1 involvement in the development of leiomyoma in a patient with schwannomatosis
    Theo J M Hulsebos
    Department of Genome Analysis, Academic Medical Center Department of Pathology, VU University Medical Center, Amsterdam Department of Pathology, Nijmegen Center for Molecular Life Sciences NCMLS, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Institute for Human Genetics, University Hospital Muenster, Muenster Institute for Neuropathology, Evangelisches Krankenhaus, Bielefeld, Germany
    Am J Surg Pathol 38:421-5. 2014
  9. doi request reprint Taqman genotyping assays can be used on decalcified and paraffin-embedded tissue from patients with osteosarcoma
    Melanie M Hagleitner
    Department of Pediatric Hematology and Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
    Pediatr Blood Cancer 56:35-8. 2011
  10. doi request reprint Noonan syndrome, the SOS1 gene and embryonal rhabdomyosarcoma
    Marjolijn C J Jongmans
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Genes Chromosomes Cancer 49:635-41. 2010

Collaborators

Detail Information

Publications14

  1. doi request reprint Presence of C11orf95-MKL2 fusion is a consistent finding in chondroid lipomas: a study of eight cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Histopathology 62:925-30. 2013
    ..Based on a recurrent translocation t(11;16)(q13;p13), the C11orf95-MKL2 fusion gene has been found in a few cases. Therefore, it seemed appropriate to look for this fusion gene in a larger cohort...
  2. doi request reprint EWSR1 gene rearrangement occurs in a subset of cutaneous myoepithelial tumors: a study of 18 cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mod Pathol 24:1444-50. 2011
    ..Our study provides a genetic relationship of myoepithelial tumors of the skin with their counterparts in soft tissue, bone and visceral localization by sharing EWSR1 rearrangement...
  3. doi request reprint EWSR1-ATF1 chimeric transcript in a myoepithelial tumor of soft tissue: a case report
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Hum Pathol 43:764-8. 2012
    ..In addition, this case indicates that there are overlapping genetic features of myoepithelial tumors, clear cell sarcoma, angiomatoid fibrous histiocytoma, and hyalinizing clear-cell carcinoma of the salivary gland...
  4. pmc NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 Nijmegen, The Netherlands
    Virchows Arch 460:621-8. 2012
    ..In summary, MECs and cEMCs share clinical, morphological, immunohistochemical and genetic characteristics. The pathognomic rearrangement of NR4A3 is a useful diagnostic feature in identifying cEMCs...
  5. pmc Fibrous dysplasia of bone associated with soft-tissue myxomas as well as an intra-osseous myxoma in a woman with Mazabraud's syndrome: a case report
    Wybren A van der Wal
    Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Postbox 9101, NL 6500 HB Nijmegen, The Netherlands
    J Med Case Reports 5:239. 2011
    ..abstract:..
  6. doi request reprint Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mod Pathol 24:82-9. 2011
    ..In conclusion, we affirm the link between cellular angiofibroma, spindle cell lipoma, and mammary-type myofibroblastoma, showing a spectrum of one entity with morphological variations dependent on anatomic location...
  7. doi request reprint Myxoid epithelioid sarcoma: a diagnostic challenge. A report on six cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Histopathology 57:753-9. 2010
    ..To characterize more clearly the myxoid variant of ES, we describe six additional cases and discuss the differential diagnoses...
  8. ncbi request reprint SMARCB1 involvement in the development of leiomyoma in a patient with schwannomatosis
    Theo J M Hulsebos
    Department of Genome Analysis, Academic Medical Center Department of Pathology, VU University Medical Center, Amsterdam Department of Pathology, Nijmegen Center for Molecular Life Sciences NCMLS, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Institute for Human Genetics, University Hospital Muenster, Muenster Institute for Neuropathology, Evangelisches Krankenhaus, Bielefeld, Germany
    Am J Surg Pathol 38:421-5. 2014
    ..To our knowledge, this is the first reported case of leiomyoma associated with a germline SMARCB1 mutation. As such, it widens the spectrum of benign tumors associated with a germline SMARCB1 mutation. ..
  9. doi request reprint Taqman genotyping assays can be used on decalcified and paraffin-embedded tissue from patients with osteosarcoma
    Melanie M Hagleitner
    Department of Pediatric Hematology and Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
    Pediatr Blood Cancer 56:35-8. 2011
    ..However, this material generally has been decalcified and formalin-fixed for many years. In our study, we investigated whether DNA obtained from these tissues can be used for reliable single nucleotide polymorphism (SNP) genotyping...
  10. doi request reprint Noonan syndrome, the SOS1 gene and embryonal rhabdomyosarcoma
    Marjolijn C J Jongmans
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Genes Chromosomes Cancer 49:635-41. 2010
    ..Sequence analysis of the SOS1 gene in 20 sporadic ERMS tumors failed to reveal any pathogenic mutations, implicating that SOS1 is not a major player in the development of this tumor outside the context of NS...
  11. ncbi request reprint The diagnostic hurdle of an elderly male with bone pain: how 18F-FDG-PET led to diagnosis of a leiomyosarcoma of the adrenal gland
    Hanneke W M van Laarhoven
    Department of Medical Oncology, Radboud University Nijmegen Medical Centre, The Netherlands
    Anticancer Res 29:469-72. 2009
    ..In this way, unnecessary and enduring suffering of symptomatic patients may be prevented...
  12. ncbi request reprint Desmoid-type fibromatosis of the head and neck region in the paediatric population: a clinicopathological and genetic study of seven cases
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Histopathology 64:769-76. 2014
    ..Desmoid-type fibromatosis (desmoid) is a locally aggressive (myo)fibroblastic lesion. It represents one of the more common fibrous tumours in children and adolescents. The head and neck region is more often involved than in adults...
  13. ncbi request reprint Radiation-induced vascular lesions of the skin: an overview
    Uta Flucke
    Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Department of Dermatology, Fundacion Jimenez Diaz, Universidad Autonoma, Madrid, Spain Dermatopathology Bodensee, Friedrichshafen, Germany
    Adv Anat Pathol 20:407-15. 2013
    ..Furthermore, advanced tailored treatment strategies in AS, one of the most aggressive type of sarcoma, rely on identifying genes and proteins involved in malignant angiogenesis. ..
  14. doi request reprint Metastatic melanoma mimicking solitary fibrous tumor: report of two cases
    Elise M Bekers
    Department of Pathology, Radboud University Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Virchows Arch 464:247-51. 2014
    ..Mutational analysis detected BRAF and NRAS mutations in the primary and secondary lesions, respectively. This result confirmed the diagnosis of recurrent/metastastic melanoma. ..