Research Topics
| Floris P de LangeSummaryAffiliation: Radboud University Nijmegen Country: The Netherlands Publications
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Detail Information
Publications
Increase in prefrontal cortical volume following cognitive behavioural therapy in patients with chronic fatigue syndromeFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6500 HB Nijmegen, The Netherlands
Brain 131:2172-80. 2008..Furthermore, our results reveal a possible neurobiological substrate of psychotherapeutic treatment...
Increased self-monitoring during imagined movements in conversion paralysisFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6500 HB Nijmegen, The Netherlands
Neuropsychologia 45:2051-8. 2007..These findings lend support to the hypothesis that conversion paralysis is associated with heightened self-monitoring during actions with the affected arm...
Neural topography and content of movement representationsFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, University of Nijmegen, The Netherlands
J Cogn Neurosci 17:97-112. 2005..We discuss the relevance of these results in the context of current models of action planning...
Gray matter volume reduction in the chronic fatigue syndromeFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, NL 6500 HB Nijmegen, The Netherlands
Neuroimage 26:777-81. 2005..These findings suggest that the central nervous system plays a key role in the pathophysiology of CFS and point to a new objective and quantitative tool for clinical diagnosis of this disabling disorder...
Posture influences motor imagery: an fMRI studyFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6500 HB Nijmegen, The Netherlands
Neuroimage 33:609-17. 2006..This motor plan is calculated by a parieto-frontal network. Within this network, the posterior parietal cortex appears to incorporate proprioceptive information related to the current position of the body into the motor plan...
Weight lifting in the human brainFloris P de Lange
Department of Intention and Action, F. C. Donders Centre for Cognitive Neuroimaging, NL-6500 HB Nijmegen, The Netherlands
J Neurosci 26:10327-8. 2006
Cerebral compensation during motor imagery in Parkinson's diseaseRick C Helmich
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, The Netherlands
Neuropsychologia 45:2201-15. 2007..These findings characterize the cerebral bases of the increased dependence on visual information processing during the generation of motor plans in PD, pointing to its compensatory role...
Increased dependence of action selection on recent motor history in Parkinson's diseaseRick C Helmich
Centre for Cognitive Neuroimaging, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands
J Neurosci 29:6105-13. 2009..The enhanced MFC activity may result either from reduced focusing abilities of the basal ganglia or from compensatory processes...
Motor imagery: a window into the mechanisms and alterations of the motor systemFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, Netherlands
Cortex 44:494-506. 2008..The increased self-monitoring evoked by explicit motor imagery can have profound cerebral consequences in a psychopathological condition...
Neural correlates of the chronic fatigue syndrome--an fMRI studyFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, University of Nijmegen, NL 6500 HB Nijmegen, The Netherlands E mail
Brain 127:1948-57. 2004..Furthermore, the between-groups differences observed during erroneous performance point to motivational disturbances as a crucial component of CFS...
Altered connectivity between prefrontal and sensorimotor cortex in conversion paralysisFloris P de Lange
Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, Kapittelweg 29, 6500 HB Nijmegen, Netherlands
Neuropsychologia 48:1782-8. 2010..Together, these results suggest that the reduced motor responsitivity observed in CP may be linked to altered dorsolateral prefrontal-motor connectivity...
Motor planning is facilitated by adopting an action's goal posture: an fMRI studyMarius Zimmermann
Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, NL 6500 HB Nijmegen, Netherlands
Cereb Cortex 22:122-31. 2012..Together, our results suggest that IPS maintains an internal state of one's own body posture, while EBA contains a representation of the goal posture of the action plan...
Attentional cues affect accuracy and reaction time via different cognitive and neural processesFreek van Ede
Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, 6525 HR Nijmegen, The Netherlands
J Neurosci 32:10408-12. 2012..These data provide new insights into the mechanisms underlying behavioral consequences of attentional cueing...
Less is more: expectation sharpens representations in the primary visual cortexPeter Kok
Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, 6500 HB Nijmegen, The Netherlands
Neuron 75:265-70. 2012..These data suggest that expectation facilitates perception by sharpening sensory representations...
Dynamic decoding of ongoing perceptionMarcel A J van Gerven
Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
Neuroimage 57:950-7. 2011..These findings extend the decoding results for static gratings and are of importance in the decoding of ongoing changes in mental state...
Attention reverses the effect of prediction in silencing sensory signalsPeter Kok
Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, The Netherlands
Cereb Cortex 22:2197-206. 2012..Our results support a predictive coding model wherein attention reverses the sensory attenuation of predicted signals...
Repetition suppression and expectation suppression are dissociable in time in early auditory evoked fieldsAna Todorović
Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behavior, 6500 HB Nijmegen, The Netherlands
J Neurosci 32:13389-95. 2012..These findings are well in line with hierarchical predictive coding models, which posit sequential stages of prediction error resolution, contingent on the level at which the hypothesis is generated...
When errors are rewardingEllen R A de Bruijn
Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HE Nijmegen, The Netherlands
J Neurosci 29:12183-6. 2009..Importantly, the current study indicates that error detection in pMFC is independent of reward and generalizes beyond our own actions, highlighting its role in optimizing performance in both individual and joint action...
Language beyond actionIvan Toni
F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, P O Box 9101, 6500 HB Nijmegen, Netherlands
J Physiol Paris 102:71-9. 2008..Without denying the enormous importance of the discovery of mirror neurons, we highlight the limits of their explanatory power for understanding language and communication...
Cerebral changes during performance of overlearned arbitrary visuomotor associationsMeike J Grol
Psychonomics Division, Helmholtz Institute, University Utrecht, 3584 CS Utrecht, The Netherlands
J Neurosci 26:117-25. 2006..More generally, our findings illustrate how rich cerebral dynamics can underlie stable behavior...
Immediate and long-term priming effects are independent of prime awarenessJolien C Francken
Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behavior, The Netherlands
Conscious Cogn 20:1793-800. 2011..Our findings imply that discriminability of information is independent of both the immediate and long-term effects that information can have on behavior...
Neural decoding with hierarchical generative modelsMarcel A J van Gerven
Radboud University Nijmegen, Institute for Computing and Information Sciences, 6525 AJ Nijmegen, The Netherlands
Neural Comput 22:3127-42. 2010..We show that by using the hierarchical generative model, we can obtain good-quality reconstructions of visual images of handwritten digits presented during an fMRI scanning session...
How awareness changes the relative weights of evidence during human decision-makingFloris P de Lange
Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, The Netherlands
PLoS Biol 9:e1001203. 2011..Our results therefore suggest a potential role of awareness in deploying flexible strategies for biasing information acquisition in line with one's expectations and goals...
Efficient Bayesian multivariate fMRI analysis using a sparsifying spatio-temporal priorMarcel A J van Gerven
Institute for Computing and Information Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
Neuroimage 50:150-61. 2010..Estimation of the posterior of interest is shown to be feasible even for very large models with thousands of variables...
How the human brain goes virtual: distinct cortical regions of the person-processing network are involved in self-identification with virtual agentsShanti Ganesh
Department of Social and Cultural Psychology, Behavioural Science Institute, Radboud University Nijmegen, 6525 HR Nijmegen, The Netherlands
Cereb Cortex 22:1577-85. 2012..These findings significantly advance our knowledge about the brain's plasticity to self-identify with virtual agents and the human cognitive-affective potential to live and learn in virtual worlds...
Motor imagery in mental rotation: an fMRI studyGuy Vingerhoets
Laboratory for Neuropsychology, Department of Internal Medicine--Section Neurology, Ghent University, Belgium
Neuroimage 17:1623-33. 2002....
Complementary systems for understanding action intentionsFloris P de Lange
F C Donders Centre for Cognitive Neuroimaging, Radboud University, NL 6500 HB, Nijmegen, Netherlands
Curr Biol 18:454-7. 2008..This supports the hypothesis that motor simulation and mentalizing have distinct but complementary functions for the recognition of others' intentions...
Inability to directly detect magnetic field changes associated with neuronal activityLaura M Parkes
F C Donders Center for Cognitive Neuroimaging, Radboud University, Nijmegen, The Netherlands
Magn Reson Med 57:411-6. 2007..This study demonstrates that for the particular stimuli and hardware used, the sensitivity of the magnitude MRI signal to detect evoked neuronal currents is too low to be of practical use...
