J A H R Claassen

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi ['Gold standard', not 'golden standard']
    J A H R Claassen
    Universitair Medisch Centrum St Radboud, Afd Geriatrie, 931, Postbus 9101, 6500 HB Nijmegen
    Ned Tijdschr Geneeskd 149:2937. 2005
  2. ncbi Cholinergically mediated augmentation of cerebral perfusion in Alzheimer's disease and related cognitive disorders: the cholinergic-vascular hypothesis
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Gerontol A Biol Sci Med Sci 61:267-71. 2006
  3. ncbi Cerebral autoregulation in Alzheimer's disease
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Donders Institute for Brain, Cognition and Behaviour, Alzheimer Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Cereb Blood Flow Metab 31:1572-7. 2011
  4. ncbi Reproducibility of cerebral blood volume measurements by near infrared spectroscopy in 16 healthy elderly subjects
    J A H R Claassen
    Department of Geriatric Medicine, Radboud University Medical Centre, Department of Geriatric Medicine, Nijmegen, The Netherlands
    Physiol Meas 27:255-64. 2006
  5. ncbi Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Radbound University Nijmegen Medical Center, The Netherlands
    J Appl Physiol 102:870-7. 2007
  6. ncbi Cerebral hemodynamics after short- and long-term reduction in blood pressure in mild and moderate hypertension
    Rong Zhang
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, University of Texas Southwestern Medical Center, TX 75231, USA
    Hypertension 49:1149-55. 2007
  7. ncbi Cerebral perfusion in neurogenic orthostatic hypotension
    Jurgen A H R Claassen
    Lancet Neurol 7:573-4; author reply 574. 2008

Collaborators

Detail Information

Publications7

  1. ncbi ['Gold standard', not 'golden standard']
    J A H R Claassen
    Universitair Medisch Centrum St Radboud, Afd Geriatrie, 931, Postbus 9101, 6500 HB Nijmegen
    Ned Tijdschr Geneeskd 149:2937. 2005
    ..Whereas the gold standard was never regarded as infallible, the incorrect term 'golden standard' implies a level of perfection that is unattainable in medical science. Consequently, the correct term should be 'gold standard'...
  2. ncbi Cholinergically mediated augmentation of cerebral perfusion in Alzheimer's disease and related cognitive disorders: the cholinergic-vascular hypothesis
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Gerontol A Biol Sci Med Sci 61:267-71. 2006
    ..Finally, we propose that the role of the cholinergic system in neurovascular regulation and functional hyperemia elucidates how the cholinergic deficit in AD contributes to the clinical and pathological features of this disease...
  3. ncbi Cerebral autoregulation in Alzheimer's disease
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Donders Institute for Brain, Cognition and Behaviour, Alzheimer Centre Nijmegen, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Cereb Blood Flow Metab 31:1572-7. 2011
    ..Further research is urgently needed to elucidate this discrepancy in the current literature, given the accumulating evidence that implicates cerebrovascular pathology in AD...
  4. ncbi Reproducibility of cerebral blood volume measurements by near infrared spectroscopy in 16 healthy elderly subjects
    J A H R Claassen
    Department of Geriatric Medicine, Radboud University Medical Centre, Department of Geriatric Medicine, Nijmegen, The Netherlands
    Physiol Meas 27:255-64. 2006
    ..The CV for long-term reproducibility was 15%. We conclude that NIRS can reproducibly measure CBV in subjects aged 65 and older, using the O(2)-method. In this group of healthy subjects, this method was well tolerated...
  5. ncbi Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing
    Jurgen A H R Claassen
    Department of Geriatric Medicine, Radbound University Nijmegen Medical Center, The Netherlands
    J Appl Physiol 102:870-7. 2007
    ..Furthermore, quantification of the CVCi-Pet(CO(2)) relationship may minimize the effects of changes in ABP on the estimation of CVMR. The method developed provides insight into CVMR under transient breath-by-breath changes in CO(2)...
  6. ncbi Cerebral hemodynamics after short- and long-term reduction in blood pressure in mild and moderate hypertension
    Rong Zhang
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, University of Texas Southwestern Medical Center, TX 75231, USA
    Hypertension 49:1149-55. 2007
    ....
  7. ncbi Cerebral perfusion in neurogenic orthostatic hypotension
    Jurgen A H R Claassen
    Lancet Neurol 7:573-4; author reply 574. 2008