Jan Buitelaar

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint A randomized, double-blind study of continuation treatment for attention-deficit/hyperactivity disorder after 1 year
    Jan K Buitelaar
    University Medical Center St Radboud, Nijmegen, The Netherlands
    Biol Psychiatry 61:694-9. 2007
  2. ncbi request reprint Does maternal prenatal stress adversely affect the child's learning and memory at age six?
    Barbara M Gutteling
    Department of Child and Adolescent Psychiatry, Utrecht University Medical Center and the Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    J Abnorm Child Psychol 34:789-98. 2006
  3. ncbi request reprint Stability and change of IQ scores in preschool children diagnosed with autistic spectrum disorder
    Claudine Dietz
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, P O 85500, 3508 GA, Utrecht, The Netherlands
    Eur Child Adolesc Psychiatry 16:405-10. 2007
  4. ncbi request reprint Finding effective screening instruments for autism using bayes theorem
    Wouter B Groen
    Child and Adolescent Psychiatry, University Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands
    Arch Pediatr Adolesc Med 161:415-6. 2007
  5. pmc Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants
    Jan Buitelaar
    Department of Psychiatry, UMC St Radboud, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 19:325-40. 2010
  6. pmc Safety and tolerability of flexible dosages of prolonged-release OROS methylphenidate in adults with attention-deficit/hyperactivity disorder
    Jan K Buitelaar
    Department of Psychiatry, University Medical Center, St Radboud and Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    Neuropsychiatr Dis Treat 5:457-66. 2009
  7. pmc Long-term efficacy and safety outcomes with OROS-MPH in adults with ADHD
    Jan K Buitelaar
    Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Neuropsychopharmacol 15:1-13. 2012
  8. pmc Callous-unemotional traits as a cross-disorders construct
    Pierre C M Herpers
    Karakter Child and Adolescent Psychiatry University Centre, Radboud University Nijmegen Medical Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 47:2045-64. 2012
  9. doi request reprint Conduct disorders
    Jan K Buitelaar
    Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behavior, PO Box 9101, 204 6500 HB, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 22:S49-54. 2013
  10. doi request reprint Predictors of placebo response in adults with attention-deficit/hyperactivity disorder: data from 2 randomized trials of osmotic-release oral system methylphenidate
    Jan K Buitelaar
    Department of Cognitive Neuroscience, University Medical Center, St Radboud and Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    J Clin Psychiatry 73:1097-102. 2012

Detail Information

Publications145 found, 100 shown here

  1. ncbi request reprint A randomized, double-blind study of continuation treatment for attention-deficit/hyperactivity disorder after 1 year
    Jan K Buitelaar
    University Medical Center St Radboud, Nijmegen, The Netherlands
    Biol Psychiatry 61:694-9. 2007
    ..The efficacy of atomoxetine in maintaining symptom response following 1 year of treatment was assessed in children and adolescents (n = 163) with DSM-IV defined attention-deficit/hyperactivity disorder (ADHD)...
  2. ncbi request reprint Does maternal prenatal stress adversely affect the child's learning and memory at age six?
    Barbara M Gutteling
    Department of Child and Adolescent Psychiatry, Utrecht University Medical Center and the Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands
    J Abnorm Child Psychol 34:789-98. 2006
    ..No associations were found between prenatal maternal cortisol and the offspring's learning and memory...
  3. ncbi request reprint Stability and change of IQ scores in preschool children diagnosed with autistic spectrum disorder
    Claudine Dietz
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, P O 85500, 3508 GA, Utrecht, The Netherlands
    Eur Child Adolesc Psychiatry 16:405-10. 2007
    ....
  4. ncbi request reprint Finding effective screening instruments for autism using bayes theorem
    Wouter B Groen
    Child and Adolescent Psychiatry, University Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands
    Arch Pediatr Adolesc Med 161:415-6. 2007
  5. pmc Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants
    Jan Buitelaar
    Department of Psychiatry, UMC St Radboud, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 19:325-40. 2010
    ..Concerns of long-term stimulant treatment are also discussed...
  6. pmc Safety and tolerability of flexible dosages of prolonged-release OROS methylphenidate in adults with attention-deficit/hyperactivity disorder
    Jan K Buitelaar
    Department of Psychiatry, University Medical Center, St Radboud and Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    Neuropsychiatr Dis Treat 5:457-66. 2009
    ..Body weight decreased slightly (-1.5 kg). The results provide additional support for the safety and tolerability of prolonged-release OROS methylphenidate in a flexible dose regimen (18-90 mg/day) for the treatment of adults with ADHD...
  7. pmc Long-term efficacy and safety outcomes with OROS-MPH in adults with ADHD
    Jan K Buitelaar
    Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Neuropsychopharmacol 15:1-13. 2012
    ..In conclusion, the short-term benefits of OROS-MPH continue during long-term open-label treatment. Maintenance of efficacy in a placebo-controlled withdrawal design remains to be confirmed in larger patient populations. ..
  8. pmc Callous-unemotional traits as a cross-disorders construct
    Pierre C M Herpers
    Karakter Child and Adolescent Psychiatry University Centre, Radboud University Nijmegen Medical Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 47:2045-64. 2012
    ....
  9. doi request reprint Conduct disorders
    Jan K Buitelaar
    Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behavior, PO Box 9101, 204 6500 HB, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 22:S49-54. 2013
    ..There is a role for medication in the treatment of comorbid syndromes and/or in case of insufficient response to psychosocial interventions and severe and dangerous aggressive and violent behaviours...
  10. doi request reprint Predictors of placebo response in adults with attention-deficit/hyperactivity disorder: data from 2 randomized trials of osmotic-release oral system methylphenidate
    Jan K Buitelaar
    Department of Cognitive Neuroscience, University Medical Center, St Radboud and Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    J Clin Psychiatry 73:1097-102. 2012
    ..To find potential correlates of placebo response in adults with attention-deficit/hyperactivity disorder (ADHD) and gain insights into why placebo response may be high in clinical trials...
  11. pmc A pilot study of abnormal growth in autism spectrum disorders and other childhood psychiatric disorders
    Nanda N J Rommelse
    Karakter, Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    J Autism Dev Disord 41:44-54. 2011
    ..Thus abnormal growth appears to be related to psychiatric disorders in general and is mainly expressed as an accelerated growth of height not matched by an increase in weight or head circumference...
  12. pmc Effects of maternal and paternal smoking on attentional control in children with and without ADHD
    Marieke E Altink
    Department of Psychiatry, Donders Centre for Neuroscience, Radboud University Nijmegen Medical Centre, P O Box 9101, HP 966, Nijmegen 6500 HB, The Netherlands
    Eur Child Adolesc Psychiatry 18:465-75. 2009
    ..Future studies should examine if the results can be generalized to other cognitive domains...
  13. pmc Predictive value of subclinical autistic traits at age 14-15 months for behavioural and cognitive problems at age 3-5 years
    Esmé Möricke
    Department of Psychiatry 966, Nijmegen Centre for Evidence Based Practice NCEBP, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 19:659-68. 2010
    ..The practical implications bear on the early recognition of children at risk for behavioural problems and for language and cognitive problems...
  14. pmc Relationship between endophenotype and phenotype in ADHD
    Nanda Nj Rommelse
    Department of Clinical Neuropsychology, VU University Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
    Behav Brain Funct 4:4. 2008
    ..abstract:..
  15. pmc The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Behav Brain Funct 4:48. 2008
    ..abstract:..
  16. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligence
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    BMC Psychiatry 11:55. 2011
    ..In particular, to investigate the influence of age, gender, family status (proband vs. sibling), informant, and centres on sample homogeneity in psychopathological measures...
  17. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Switzerland
    BMC Psychiatry 11:54. 2011
    ..A particular focus was on the effects of the study design and the diagnostic procedure on the homogeneity of the sample in terms of symptom-based behavioural data, and potential consequences for further analyses based on these data...
  18. ncbi request reprint A comparison of North American versus non-North American ADHD study populations
    Jan K Buitelaar
    Dept of Psychiatry, Academic Centre for Child and Adolescent Psychiatry, University Medical Centre St Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 15:177-81. 2006
    ..This supports the practice of generalizing results from treatment studies across geographies...
  19. doi request reprint Comparison of symptomatic versus functional changes in children and adolescents with ADHD during randomized, double-blind treatment with psychostimulants, atomoxetine, or placebo
    Jan K Buitelaar
    Department of Psychiatry, Radboud University Nijmegen Medical Centre and Karakter University Centre for Child and Adolescent Psychiatry, Nijmegen, The Netherlands
    J Child Psychol Psychiatry 50:335-42. 2009
    ....
  20. doi request reprint Predictors of treatment outcome in adults with ADHD treated with OROS® methylphenidate
    Jan K Buitelaar
    UMC St Radboud, Department of Cognitive Neuroscience, Nijmegen, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 35:554-60. 2011
    ....
  21. ncbi request reprint Foreword -- ADHD in the scientific and political context
    Jan K Buitelaar
    Dept of Psychiatry 333, University Medical Center St Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 13:I1-6. 2004
    ..Not only a European perspective" underlines this perspective and reflects a broad spectrum of ADHD-related activities currently underway in Europe while having the worldwide development of the field in mind...
  22. pmc Functional improvement and correlations with symptomatic improvement in adults with attention deficit hyperactivity disorder receiving long-acting methylphenidate
    J K Buitelaar
    Department of Cognitive Neuroscience, University Medical Centre, St Radboud and Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands
    Psychol Med 42:195-204. 2012
    ..Daily functioning was assessed as part of an open-label extension, and associations with symptom scores were evaluated...
  23. doi request reprint Neural basis of recollection in first-episode major depression
    Philip van Eijndhoven
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, HB Nijmegen, The Netherlands
    Hum Brain Mapp 34:283-94. 2013
    ..Here, we used an event-related fMRI design, to dissociate hippocampal and prefrontal contributions to the neural processes involved in recollection success and recollection attempt early in the course of MDD...
  24. doi request reprint The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli
    Guido van Wingen
    Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    Neuroimage 50:1212-8. 2010
    ..Furthermore, the sex-specific genotype effects may contribute to sex-specific effects of BDNF Val66Met on depression vulnerability...
  25. doi request reprint The dopamine transporter haplotype and reward-related striatal responses in adult ADHD
    Martine Hoogman
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    Eur Neuropsychopharmacol 23:469-78. 2013
    ..Although the importance of the DAT1 haplotype as a risk factor for adult ADHD was again demonstrated in this study, the mechanism by which this gene increases disease risk remains largely unknown...
  26. ncbi request reprint Contributions of the medial temporal lobe to declarative memory retrieval: manipulating the amount of contextual retrieval
    Indira Tendolkar
    Department of Psychiatry, Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands
    Learn Mem 15:611-7. 2008
    ..If one assumes departure from linearity, however, our results can also be explained by one-dimensional modulation of memory strength...
  27. doi request reprint Exceptions and anomalies: an ERP study on context sensitivity in autism
    Judith Pijnacker
    Donders Institute for Brain, Cognition and Behaviour, Centre for Cognitive Neuroimaging, Radboud University Nijmegen, The Netherlands
    Neuropsychologia 48:2940-51. 2010
    ..Because sentence context had a modulating effect in a later phase, semantic integration is perhaps less automatic in HFA, and presumably more elaborate processes are needed to arrive at a sentence interpretation...
  28. ncbi request reprint Motor flexibility problems as a marker for genetic susceptibility to attention-deficit/hyperactivity disorder
    Dorine Slaats-Willemse
    Academic Center for Child and Adolescent Psychiatry Oost Nederland, University Medical Center St Radboud, Reinier Postlaan 12, 6525 GC Nijmegen, The Netherlands
    Biol Psychiatry 58:233-8. 2005
    ..We hypothesized that if fine motor problems may be a marker for genetic susceptibility to ADHD, nonaffected siblings of ADHD probands would experience motor problems similar to those of their ADHD siblings...
  29. doi request reprint Nitric oxide synthase genotype modulation of impulsivity and ventral striatal activity in adult ADHD patients and healthy comparison subjects
    Martine Hoogman
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, The Netherlands
    Am J Psychiatry 168:1099-106. 2011
    ..In the present study, the authors investigated the effect of a functional variable number of tandem repeats (VNTR) polymorphism in NOS1 (NOS1 exon 1f-VNTR) on the processing of rewards, one of the cognitive deficits in ADHD...
  30. doi request reprint Amygdala responsivity related to memory of emotionally neutral stimuli constitutes a trait factor for depression
    Philip van Eijndhoven
    Radboud University Nijmegen Medical Centre, Department of Psychiatry, Nijmegen, The Netherlands
    Neuroimage 54:1677-84. 2011
    ..These findings represent initial evidence for a neurocognitive trait or vulnerability marker of depression-amygdala involvement in episodic memory formation of neutral stimuli...
  31. ncbi request reprint DAT1, DRD4, and DRD5 polymorphisms are not associated with ADHD in Dutch families
    Steven C Bakker
    Department of Psychiatry, A 00 241, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 132:50-2. 2005
    ..These data suggest that DAT1, DRD4, and DRD5 do not contribute substantially to ADHD in the Dutch population...
  32. ncbi request reprint Amygdala and hippocampus enlargement during adolescence in autism
    Wouter Groen
    Donders Institute for Brain Cognition and Behavior, Centre for Cognitive Neuroimaging, Nijmegen, The Netherlands
    J Am Acad Child Adolesc Psychiatry 49:552-60. 2010
    ..Although some studies in children with autism suggest that there is an enlargement of amygdala and hippocampal volume, findings in adolescence are sparse...
  33. doi request reprint Head circumference and height abnormalities in autism revisited: the role of pre- and perinatal risk factors
    Margo Schrieken
    Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 22:35-43. 2013
    ..However, prospective studies measuring growth and ASD characteristics in both premature/low birth weight and a terme children are necessary to support this conclusion...
  34. pmc Current self-reported symptoms of attention deficit/hyperactivity disorder are associated with total brain volume in healthy adults
    Martine Hoogman
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    PLoS ONE 7:e31273. 2012
    ..In order to get a better understanding of the neurobiology of ADHD, we take the first step in studying the dimensionality of current self-reported adult ADHD symptoms, by looking at its relation with total brain volume...
  35. doi request reprint How useful is the Social Communication Questionnaire in toddlers at risk of autism spectrum disorder?
    Iris Oosterling
    Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, Nijmegen, The Netherlands
    J Child Psychol Psychiatry 51:1260-8. 2010
    ..Indices of diagnostic accuracy have been shown to be strong in school-aged samples; however, relatively little is known about the performance of the SCQ in toddlers at risk of autism spectrum disorder (ASD)...
  36. doi request reprint Reasoning with exceptions: an event-related brain potentials study
    Judith Pijnacker
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    J Cogn Neurosci 23:471-80. 2011
    ..Possible accounts for the observed effect are discussed...
  37. doi request reprint Impaired task switching performance in children with dyslexia but not in children with autism
    Edita Poljac
    Radboud University Nijmegen, Nijmegen, The Netherlands
    Q J Exp Psychol (Hove) 63:401-16. 2010
    ..The implications of our data are further discussed in relation to the interpretation of the Wisconsin Card Sorting Test...
  38. doi request reprint Familiality of major depressive disorder and patterns of lifetime comorbidity. The NEMESIS and GenMood studies. A comparison of three samples
    Maaike Verhagen
    Department of Psychiatry 966, Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands
    Eur Arch Psychiatry Clin Neurosci 258:505-12. 2008
    ..This study examined whether familiality of MDD is associated with the presence of specific comorbid disorders, which might be an important factor to be taken into account in MDD treatment and research into MDD etiology...
  39. pmc The dopamine receptor D4 7-repeat allele and prenatal smoking in ADHD-affected children and their unaffected siblings: no gene-environment interaction
    Marieke E Altink
    Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, The Netherlands
    J Child Psychol Psychiatry 49:1053-60. 2008
    ....
  40. doi request reprint Amygdala volume marks the acute state in the early course of depression
    Philip van Eijndhoven
    Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Biol Psychiatry 65:812-8. 2009
    ..It remains unclear how much structural and functional changes of amygdala and hippocampus reflect the acute state of depression or an underlying neurobiological trait marker of depression...
  41. doi request reprint Testosterone reduces amygdala-orbitofrontal cortex coupling
    Guido van Wingen
    Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Kapittelweg 29, 6525 EN Nijmegen, The Netherlands
    Psychoneuroendocrinology 35:105-13. 2010
    ..Because interhemispheric amygdala coupling is lower in men than in women, this result suggests that circulating testosterone may contribute to this sexual dimorphism...
  42. doi request reprint The crown of love: intimate relations and alcohol use in adolescence
    Carmen S van der Zwaluw
    Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 18:407-17. 2009
    ..In the current study, we examined associations between adolescent alcohol use and romantic partners' drinking behavior...
  43. doi request reprint Lifespan attention deficit/hyperactivity disorder and borderline personality disorder symptoms in female patients: a latent class approach
    Fiona van Dijk
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, HB Nijmegen, The Netherlands
    Psychiatry Res 190:327-34. 2011
    ..ADHD classification subtypes may not be permanent over time, and different developmental pathways to adult ADHD and BPD should therefore be investigated...
  44. ncbi request reprint Atomoxetine for attention-deficit/hyperactivity disorder symptoms in children with pervasive developmental disorders: a pilot study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 16:611-9. 2006
    ..This pilot study examined the effects of atomoxetine on attention-deficit/hyperactivity disorder (ADHD) symptoms and autistic features in children with pervasive developmental disorders (PDD)...
  45. doi request reprint Medically unexplained physical symptoms in elderly people: a pilot study of psychiatric geriatric characteristics
    Peter H Hilderink
    GGz Nijmegen, Department of Old Age Psychiatry, Radboud Univeristy Nijmegen Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, The Netherlands
    Am J Geriatr Psychiatry 17:1085-8. 2009
    ..To examine the somatic complaints, functional impairment, and psychiatric comorbidity in elderly patients with medically unexplained symptoms (MUSs)...
  46. doi request reprint Psychomotor planning is deficient in recent-onset schizophrenia
    Koen P Grootens
    Department of Psychiatry, University Medical Center St Radboud, and Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
    Schizophr Res 107:294-302. 2009
    ..The aim of the present study is to test the hypothesis that such deficits are already present in patients with recent-onset schizophrenia...
  47. ncbi request reprint Measurement and genetics of human subcortical and hippocampal asymmetries in large datasets
    Tulio Guadalupe
    Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands International Max Planck Research School for Language Sciences, Max Planck Insitute for Psycholinguistics, Nijmegen, The Netherlands
    Hum Brain Mapp 35:3277-89. 2014
    ..Hum Brain Mapp 35:3277-3289, 2014. © 2013 Wiley Periodicals, Inc. ..
  48. pmc Working memory capacity predicts effects of methylphenidate on reversal learning
    Marieke E van der Schaaf
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neuropsychopharmacology 38:2011-8. 2013
    ..Moreover, they highlight the importance of taking into account both inter- and intra-individual differences in dopaminergic drug research...
  49. doi request reprint Severe fatigue in narcolepsy with cataplexy
    Hal A Droogleever Fortuyn
    Department of Psychiatry, Radboud University Nijmegen Medical Center, The Netherlands
    J Sleep Res 21:163-9. 2012
    ..In conclusion, a majority of patients with narcolepsy suffer from severe fatigue, which can be distinguished from daytime sleepiness, and results in severe functional impairment...
  50. doi request reprint ADHD and poor motor performance from a family genetic perspective
    Ellen Fliers
    Bavo Europoort Youth Department, Twentestraat 52, 3083 BD Rotterdam, The Netherlands
    J Am Acad Child Adolesc Psychiatry 48:25-34. 2009
    ....
  51. pmc Actual motor performance and self-perceived motor competence in children with attention-deficit hyperactivity disorder compared with healthy siblings and peers
    Ellen A Fliers
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Dev Behav Pediatr 31:35-40. 2010
    ..In this cross-sectional study, the relationship between actual motor performance and perceived motor competence was examined...
  52. pmc Pervasive microstructural abnormalities in autism: a DTI study
    Wouter B Groen
    Karakter, Child and Adolescent Psychiatry University Center, P O Box 9101, 6500 HB Nijmegen, TheNetherlands
    J Psychiatry Neurosci 36:32-40. 2011
    ..Since autism is a developmental disorder, we aim to investigate the nature and location of decreases in white and grey matter integrity in an adolescent sample while accounting for age...
  53. ncbi request reprint A controlled study of formal thought disorder in children with autism and multiple complex developmental disorders
    Rutger J van der Gaag
    University Medical Centre St Radboud Nijmegen Academic Centre for Child and Adolescent Psychiatry, Nijmegen, The Netherlands
    J Child Adolesc Psychopharmacol 15:465-76. 2005
    ....
  54. doi request reprint The dopamine agonist apomorphine differentially affects cognitive performance in alcohol dependent patients and healthy controls
    Arnt F A Schellekens
    Department of Psychiatry, University Medical Centre St Radboud, Nijmegen, The Netherlands
    Eur Neuropsychopharmacol 19:68-73. 2009
    ..Little is known on functional changes in the fronto-striatal-thalamic dopaminergic neurocircuitry in these patients. The objective of this study was to assess sensitivity of prefrontal dopamine receptors in alcohol dependent patients...
  55. doi request reprint Early and late components of error monitoring in violent offenders with psychopathy
    Inti A Brazil
    Department of Psychiatry, Donders Centre for Neurosciences, University Medical Center St Radboud, Nijmegen, The Netherlands Pompestichting, Nijmegen, The Netherlands
    Biol Psychiatry 65:137-43. 2009
    ..One of the most recognizable features of psychopathy is the reduced ability to successfully learn and adapt overt behavior. This might be due to deficient processing of error information indicating the need to adapt controlled behavior...
  56. doi request reprint Increased p50 gating but intact prepulse inhibition in borderline personality disorder
    Koen P Grootens
    CW2 Hospital Nijmegen, Department of Psychiatry A15, P O Box 9015, 6500 GS Nijmegen, The Netherlands
    J Neuropsychiatry Clin Neurosci 20:348-56. 2008
    ..The higher early preattentive and mid-latency evoked potentials suggest a higher response tendency in borderline personality disorder, but this needs further replication...
  57. doi request reprint A review and analysis of the relationship between neuropsychological measures and DAT1 in ADHD
    Nanda N J Rommelse
    Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 147:1536-46. 2008
    ....
  58. doi request reprint Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls
    Nanda N J Rommelse
    Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 147:1524-30. 2008
    ..01). These findings suggest that the genetic and neuropsychological mechanisms underlying ADHD may be different in boys and girls and underline the importance of taking into account sex effects when studying ADHD...
  59. ncbi request reprint Facilitated attentional disengagement from negative information in relation to self-reported depressive symptoms of Dutch female undergraduate students
    Patricia A M Van Deurzen
    Donders Institute for Brain, Cognition, and Behavior, Department of Psychiatry, Radboud University Nijmegen Medical Centre, Karakter Child and Adolescent Psychiatry, University Centre Nijmegen, The Netherlands
    Psychol Rep 108:252-62. 2011
    ..An explanation for the discrepancy with findings from Koster, et al. may be the different stimulus presentation time (1000 msec. instead of 500 or 1500 msec.)...
  60. doi request reprint Effect of the 5-HTTLPR polymorphism in the serotonin transporter gene on major depressive disorder and related comorbid disorders
    Maaike Verhagen
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Psychiatr Genet 19:39-44. 2009
    ..This could be because of the phenotypic heterogeneity of MDD, as it often presents with comorbid disorders such as generalized anxiety disorder (GAD), alcohol-related disorders, and dysthymia...
  61. doi request reprint Intact spectral but abnormal temporal processing of auditory stimuli in autism
    Wouter B Groen
    Karakter, Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
    J Autism Dev Disord 39:742-50. 2009
    ..008). Thus, the autism group was less able to integrate auditory information present in temporal dips in background sound, supporting the complexity-specific perceptual account...
  62. pmc Externalizing behaviors in preadolescents: familial risk to externalizing behaviors and perceived parenting styles
    Cathelijne J M Buschgens
    Department of Psychiatry, Radboud University, Nijmegen Medical Centre, PO Box 9101, HP 966, 6500 HB, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 19:567-75. 2010
    ....
  63. doi request reprint Neural state and trait bases of mood-incongruent memory formation and retrieval in first-episode major depression
    Guido A van Wingen
    Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    J Psychiatr Res 44:527-34. 2010
    ..These distinct neural mechanisms may respectively constitute symptom maintenance and cognitive vulnerability factors for depression...
  64. pmc Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD
    Barbara Franke
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neuropsychopharmacology 35:656-64. 2010
    ..However, the data might also imply that DAT1 has a modulatory rather than causative role in ADHD...
  65. doi request reprint Anxiety and mood disorders in narcolepsy: a case-control study
    H A Droogleever Fortuyn
    Department of Psychiatry, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Gen Hosp Psychiatry 32:49-56. 2010
    ..Although many authors suggest an overrepresentation of mood disorders, few systematic studies have been performed and conflicting results have been reported. Anxiety disorders in narcolepsy have only received little attention...
  66. ncbi request reprint Prenatal exposure to testosterone and functional cerebral lateralization: a study in same-sex and opposite-sex twin girls
    Celina C C Cohen-Bendahan
    Department of Psychiatry, University Medical Center St Radboud, Nijmegen, The Netherlands
    Psychoneuroendocrinology 29:911-6. 2004
    ..Secondly, as predicted OS girls had a more masculine pattern of cerebral lateralization, than SS girls. These findings support the notion of an influence of prenatal T on early brain organization in girls...
  67. pmc Does HPA-axis activity mediate the relationship between obstetric complications and externalizing behavior problems? The TRAILS study
    Rianne Marsman
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 18:565-73. 2009
    ..Future research should focus on understanding the mechanism through which OCs cause externalizing behavior problems...
  68. ncbi request reprint Maternal prenatal stress and 4-6 year old children's salivary cortisol concentrations pre- and post-vaccination
    Barbara M Gutteling
    Department of Psychiatry, Radboud University Nijmegen, Medical Center, The Netherlands
    Stress 7:257-60. 2004
    ..Furthermore, more daily hassles and a higher level of fear of bearing a handicapped child during pregnancy were associated with higher concentrations of cortisol in the children...
  69. pmc Comorbid problems in ADHD: degree of association, shared endophenotypes, and formation of distinct subtypes. Implications for a future DSM
    Nanda N J Rommelse
    Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands
    J Abnorm Child Psychol 37:793-804. 2009
    ..No such results were found for oppositional defiant behaviors and anxiety. ADHD in co-occurrence with comorbid problems may not be best seen as a distinct subtype of ADHD, but further research is warranted...
  70. ncbi request reprint Prenatal stress and children's cortisol reaction to the first day of school
    Barbara M Gutteling
    Department of Psychiatry 333, Radbond University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Psychoneuroendocrinology 30:541-9. 2005
    ..In addition, the circadian rhythm of cortisol on school days appeared to have a steeper slope as compared to that of the circadian curve on a weekend day...
  71. pmc Neuropsychological measures probably facilitate heritability research of ADHD
    Nanda N J Rommelse
    Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands
    Arch Clin Neuropsychol 23:579-91. 2008
    ..These findings suggest heritability research in ADHD will probably be facilitated by including neuropsychological measures...
  72. ncbi request reprint The effect of ondansetron, a 5-HT3 receptor antagonist, in chronic fatigue syndrome: a randomized controlled trial
    Gerard K H The
    Radboud University Nijmegen Medical Centre, Department of Psychiatry, 966, Reinier Postlaan 10, 6525 GC Nijmegen, The Netherlands
    J Clin Psychiatry 71:528-33. 2010
    ..In this randomized controlled clinical trial, the effect of ondansetron, a 5-HT(3) receptor antagonist, was assessed on fatigue severity and functional impairment in adult patients with chronic fatigue syndrome...
  73. ncbi request reprint Family-genetic study of executive functioning in attention-deficit/hyperactivity disorder: Evidence for an endophenotype?
    Dorine I E Slaats-Willemse
    Rudolph Magnus Center for Neurosciences, University Medical Center Utrecht, The Netherlands
    Neuropsychology 21:751-60. 2007
    ..These results suggest that these executive functions may be suitable endophenotypes of ADHD...
  74. ncbi request reprint Hyperactive night and day? Actigraphy studies in adult ADHD: a baseline comparison and the effect of methylphenidate
    A Marije Boonstra
    University Medical Center Utrecht, Department of Psychiatry, Utrecht, The Netherlands
    Sleep 30:433-42. 2007
    ..To investigate parameters of sleep, activity, and circadian rhythm, as well as the effects of methylphenidate on these variables, in adults with ADHD...
  75. ncbi request reprint Attention-deficit/hyperactivity disorder and social dysfunctioning
    Judith S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Clin Psychol Rev 28:692-708. 2008
    ..Future research should address the exact nature and long-term consequences of social dysfunctioning in children with ADHD, and focus on development of effective treatment strategies...
  76. ncbi request reprint Inhibition errors in borderline personality disorder with psychotic-like symptoms
    Koen P Grootens
    Radboud University Nijmegen Medical Center, Dept of Psychiatry, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 32:267-73. 2008
    ..Furthermore, we investigated whether these inhibition errors were more prominent among BPD patients with psychotic-like symptoms than among BPD patients without these symptoms...
  77. ncbi request reprint Prenatal stress and mixed-handedness
    Barbara M Gutteling
    Department of Psychiatry, Radboud University Medical Center St Radboud, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
    Pediatr Res 62:586-90. 2007
    ..In conclusion, reported and physiologic measures of prenatal stress in a moderately stressed pregnant population were only partly related to offspring mixed-handedness...
  78. ncbi request reprint Psychotic symptoms in narcolepsy: phenomenology and a comparison with schizophrenia
    Hal A Droogleever Fortuyn
    Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Gen Hosp Psychiatry 31:146-54. 2009
    ..We also compared the prevalence of formal psychotic disorders between narcolepsy patients and controls...
  79. pmc Acute effects of MDMA (3,4-methylenedioxymethamphetamine) on EEG oscillations: alone and in combination with ethanol or THC (delta-9-tetrahydrocannabinol)
    Marieke M Lansbergen
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Psychopharmacology (Berl) 213:745-56. 2011
    ..Typical users of 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") are polydrug users, combining MDMA with alcohol or cannabis [most active compound: delta-9-tetrahydrocannabinol (THC)]...
  80. pmc Problem behavior in a community sample of 14- and 19-month-old children: common versus uncommon behaviors, structure, and stability
    Anne Claire E Beernink
    Dept of Psychiatry, University Medical Center St Radboud, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 16:271-80. 2007
    ..These results will facilitate the recognition of psychopathology at very early age and the study of its development over time...
  81. doi request reprint Gender in voice perception in autism
    Wouter B Groen
    Karakter, Child and Adolescent Psychiatry University Center, 6500 HB, Nijmegen, The Netherlands
    J Autism Dev Disord 38:1819-26. 2008
    ..The differences in response times suggest that individuals with HFA use different perceptual approaches from those used by typically developing individuals...
  82. doi request reprint Externalizing behaviors in preadolescents: familial risk to externalizing behaviors, prenatal and perinatal risks, and their interactions
    Cathelijne J M Buschgens
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 18:65-74. 2009
    ..We investigated whether familial risk (FR) to externalizing behaviors and prenatal and perinatal risk factors, separately or in interaction with each other, predicted externalizing behaviors...
  83. doi request reprint The phenotype and neural correlates of language in autism: an integrative review
    Wouter B Groen
    Karakter, Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands
    Neurosci Biobehav Rev 32:1416-25. 2008
    ....
  84. doi request reprint Cardiac disease, depressive symptoms, and incident stroke in an elderly population
    Lonneke Wouts
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Arch Gen Psychiatry 65:596-602. 2008
    ..However, the reliability of much research is limited by the lack of documentation on the presence of preexistent cardiovascular disease and by the use of limited measures of depression or stroke...
  85. pmc Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder
    Nanda N J Rommelse
    Department of Psychiatry, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Center, Reinier Postlaan 10, Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 19:281-95. 2010
    ..Multivariate multi-level models are probably best suited for the statistical analysis...
  86. doi request reprint HPA-axis activity and externalizing behavior problems in early adolescents from the general population: the role of comorbidity and gender The TRAILS study
    Rianne Marsman
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Psychoneuroendocrinology 33:789-98. 2008
    ..It would be useful to consider how other risk factors such as life events and family and parenting factors as well as genetic risks affect the complex relationship between externalizing behavior problems and HPA-axis activity...
  87. doi request reprint The increase in theta/beta ratio on resting-state EEG in boys with attention-deficit/hyperactivity disorder is mediated by slow alpha peak frequency
    Marieke M Lansbergen
    Department of Psychiatry, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 35:47-52. 2011
    ..Future research should elucidate the functional role of resting-state brain oscillations by investigating neurophysiological subgroups, which may have a clearer relation to cognitive functions than single frequency bands...
  88. ncbi request reprint Pragmatic inferences in high-functioning adults with autism and Asperger syndrome
    Judith Pijnacker
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    J Autism Dev Disord 39:607-18. 2009
    ..Moreover, our results suggest that verbal intelligence is a constraint for task performance in autistic disorder but not in Asperger syndrome...
  89. pmc High prevalence of eating disorders in narcolepsy with cataplexy: a case-control study
    Hal A Droogleever Fortuyn
    Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Sleep 31:335-41. 2008
    ..To study the prevalence of and symptoms of eating disorders in patients with narcolepsy...
  90. doi request reprint Do cognitive measures of response inhibition differentiate between attention deficit/hyperactivity disorder and borderline personality disorder?
    Fiona van Dijk
    Radboud University Nijmegen Medical Centre, Department of Psychiatry 961, P O Box 9101, 6500 HB, Nijmegen, The Netherlands Electronic address
    Psychiatry Res 215:733-9. 2014
    ..The findings suggest response inhibition problems to be present in both ADHD and BPD, and patients with BPD to be particularly impaired due to poor context processing. ..
  91. ncbi request reprint Neuropsychological effects of risperidone in children with pervasive developmental disorders: a blinded discontinuation study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 16:561-73. 2006
    ..Little is known about the neuropsychological effects of risperidone in children with pervasive developmental disorders...
  92. ncbi request reprint A prospective, multicenter, open-label assessment of atomoxetine in non-North American children and adolescents with ADHD
    Jan K Buitelaar
    Department of Psychiatry, University Medical Center Nijmegen, 9101, 6500, HB Nijmegen, The Netherlands
    Eur Child Adolesc Psychiatry 13:249-57. 2004
    ..The aim of this study was to study treatment response to atomoxetine in a large, multicenter study of non-North American patients with ADHD...
  93. ncbi request reprint Physiological stress reactivity in human pregnancy--a review
    Carolina de Weerth
    Department of Psychiatry, University Medical Center Nijmegen, HP 333, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Neurosci Biobehav Rev 29:295-312. 2005
    ..These methodological points are general and can therefore also be of use for researchers studying human stress reactivity in other populations and ages...
  94. ncbi request reprint Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings
    Sarah Durston
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    J Am Acad Child Adolesc Psychiatry 43:332-40. 2004
    ..To study the influence of increased familial risk for attention-deficit/hyperactivity disorder (ADHD) on brain morphology...
  95. doi request reprint Unification of speaker and meaning in language comprehension: an FMRI study
    Cathelijne M J Y Tesink
    F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, The Netherlands
    J Cogn Neurosci 21:2085-99. 2009
    ....
  96. doi request reprint Brain alterations in adult ADHD: effects of gender, treatment and comorbid depression
    A Marten H Onnink
    Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behavior, Department of Psychiatry, Nijmegen, The Netherlands Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behavior, Department of Cognitive Neuroscience, Nijmegen, The Netherlands
    Eur Neuropsychopharmacol 24:397-409. 2014
    ..Smaller hippocampus volume in ADHD patients with previous MDD is consistent with neurobiological alterations observed in MDD. ..
  97. pmc Randomized controlled trial of the focus parent training for toddlers with autism: 1-year outcome
    Iris Oosterling
    Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, Nijmegen, The Netherlands
    J Autism Dev Disord 40:1447-58. 2010
    ....