Freek W A Verheugt

Summary

Affiliation: Onze Lieve Vrouwe Gasthuis
Country: The Netherlands

Publications

  1. pmc The role of aspirin in women's health
    Freek Wa Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis OLVG, Amsterdam, The Netherlands
    Int J Womens Health 3:151-66. 2011
  2. pmc Effectiveness of two intensive treatment methods for smoking cessation and relapse prevention in patients with coronary heart disease: study protocol and baseline description
    Nadine Berndt
    Department of Psychology, Open University of the Netherlands, Heerlen, The Netherlands
    BMC Cardiovasc Disord 12:33. 2012
  3. doi request reprint Advances in stroke prevention in atrial fibrillation: enhanced risk stratification combined with the newer oral anticoagulants
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Clin Cardiol 36:312-22. 2013
  4. doi request reprint Low-dose anticoagulation for secondary prevention in acute coronary syndrome
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Am J Cardiol 111:618-26. 2013
  5. pmc Antithrombotic therapy in heart failure
    F W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis OLVG, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands
    Neth Heart J 20:176-8. 2012
  6. doi request reprint Anticoagulant management in the cardiovascular setting
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, 9 Oosterpark, Amsterdam, The Netherlands
    Fundam Clin Pharmacol 26:11-5. 2012
  7. ncbi request reprint [New antithrombotics for atrial fibrillation]
    Freek Verheugt
    Universitair Medisch Centrum St Radboud, afd Cardiologie, Nijmegen, The Netherlands
    Ned Tijdschr Geneeskd 155:A2143. 2011
  8. doi request reprint Incidence, prognostic impact, and influence of antithrombotic therapy on access and nonaccess site bleeding in percutaneous coronary intervention
    Freek W A Verheugt
    Radboud University Medical Centre, Nijmegen, The Netherlands
    JACC Cardiovasc Interv 4:191-7. 2011
  9. doi request reprint Novel oral anticoagulants to prevent stroke in atrial fibrillation
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Oosterpark 9, 1091 AC Amsterdam, The Netherlands
    Nat Rev Cardiol 7:149-54. 2010
  10. ncbi request reprint Timing of angiography after fibrinolysis for ST-elevation acute myocardial infarction
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Curr Opin Cardiol 25:302-4. 2010

Detail Information

Publications62

  1. pmc The role of aspirin in women's health
    Freek Wa Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis OLVG, Amsterdam, The Netherlands
    Int J Womens Health 3:151-66. 2011
    ..The aim of this review is to discuss the role of aspirin for various conditions in women...
  2. pmc Effectiveness of two intensive treatment methods for smoking cessation and relapse prevention in patients with coronary heart disease: study protocol and baseline description
    Nadine Berndt
    Department of Psychology, Open University of the Netherlands, Heerlen, The Netherlands
    BMC Cardiovasc Disord 12:33. 2012
    ....
  3. doi request reprint Advances in stroke prevention in atrial fibrillation: enhanced risk stratification combined with the newer oral anticoagulants
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Clin Cardiol 36:312-22. 2013
    ..This, coupled with advances in stroke risk stratification, is expected to improve patient outcomes and reduce the burden of AF-related stroke...
  4. doi request reprint Low-dose anticoagulation for secondary prevention in acute coronary syndrome
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Am J Cardiol 111:618-26. 2013
    ....
  5. pmc Antithrombotic therapy in heart failure
    F W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis OLVG, Oosterpark 9, 1091 AC, Amsterdam, The Netherlands
    Neth Heart J 20:176-8. 2012
    ....
  6. doi request reprint Anticoagulant management in the cardiovascular setting
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, 9 Oosterpark, Amsterdam, The Netherlands
    Fundam Clin Pharmacol 26:11-5. 2012
    ..Rivaroxaban, apixaban (both oral direct Factor Xa inhibitors) and dabigatran (a direct thrombin inhibitor) all exhibit predictable anticoagulant responses and few drug-drug interactions and do not require routine coagulation monitoring...
  7. ncbi request reprint [New antithrombotics for atrial fibrillation]
    Freek Verheugt
    Universitair Medisch Centrum St Radboud, afd Cardiologie, Nijmegen, The Netherlands
    Ned Tijdschr Geneeskd 155:A2143. 2011
    ..Long-term safety of the new agents in patients with atrial fibrillation has not yet been determined...
  8. doi request reprint Incidence, prognostic impact, and influence of antithrombotic therapy on access and nonaccess site bleeding in percutaneous coronary intervention
    Freek W A Verheugt
    Radboud University Medical Centre, Nijmegen, The Netherlands
    JACC Cardiovasc Interv 4:191-7. 2011
    ..The aim of this study was to evaluate the relative frequency of access and nonaccess site bleeding, the association of these events with 1-year mortality, and the impact of randomized antithrombotic therapy...
  9. doi request reprint Novel oral anticoagulants to prevent stroke in atrial fibrillation
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Oosterpark 9, 1091 AC Amsterdam, The Netherlands
    Nat Rev Cardiol 7:149-54. 2010
    ..In one of these trials an oral thrombin blocker has so far shown superiority to warfarin in efficacy and safety. In this Review, I address the potential of modern oral anticoagulants to improve stroke prevention in atrial fibrillation...
  10. ncbi request reprint Timing of angiography after fibrinolysis for ST-elevation acute myocardial infarction
    Freek W A Verheugt
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Curr Opin Cardiol 25:302-4. 2010
    ..Apart from bleeding, early reocclusion of the culprit artery is a common complication of the therapy and usually leads to a worse prognosis...
  11. doi request reprint Diverging associations of an intended early invasive strategy compared with actual revascularization, and outcome in patients with non-ST-segment elevation acute coronary syndrome: the problem of treatment selection bias
    Alexander Hirsch
    Department of Cardiology, B2 137, Academic Medical Center, Meibergdreef 9, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Eur Heart J 30:645-54. 2009
    ..We investigated the association between actual in-hospital revascularization and long-term outcome in patients with nSTE-ACS included in the ICTUS trial...
  12. ncbi request reprint ST-segment deviation on the admission electrocardiogram, treatment strategy, and outcome in non-ST-elevation acute coronary syndromes A substudy of the Invasive versus Conservative Treatment in Unstable coronary Syndromes (ICTUS) Trial
    Fons Windhausen
    Department of Cardiology of the Academic Medical Center, Amsterdam, The Netherlands
    J Electrocardiol 40:408-15. 2007
    ....
  13. doi request reprint Highly sensitive cardiac troponin T and long-term mortality in a population of community-derived perimenopausal women: nested case-control study
    G Etienne Cramer
    Department of Cardiology 670, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Heart 99:528-33. 2013
    ..To assess the association between baseline levels of highly sensitive cardiac troponin T (hs-cTnT) and long-term mortality in perimenopausal women of the general community using a gender specific 99th percentile reference limit...
  14. ncbi request reprint Prehospital fibrinolysis with dual antiplatelet therapy in ST-elevation acute myocardial infarction: a substudy of the randomized double blind CLARITY-TIMI 28 trial
    Freek W A Verheugt
    Department of Cardiology, 670 Cardiology, Heartcenter, University Medical Center St Radboud, 10 Geert Grooteplein Zuid, Nijmegen 6525, The Netherlands
    J Thromb Thrombolysis 23:173-9. 2007
    ..Intensified prehospital management of STEMI may shorten time to treatment and improve outcomes...
  15. ncbi request reprint Antiplatelet therapy and progression of coronary artery disease: a placebo-controlled trial with angiographic and clinical follow-up after myocardial infarction
    Hendrik Jan Dieker
    Department of Cardiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Am Heart J 153:66.e1-8. 2007
    ..Whether antiplatelet therapy influences the often subclinical process of coronary disease progression in noninfarct arteries has not been reported...
  16. doi request reprint Cystatin C for enhancement of risk stratification in non-ST elevation acute coronary syndrome patients with an increased troponin T
    Fons Windhausen
    Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
    Clin Chem 55:1118-25. 2009
    ....
  17. ncbi request reprint Prehospital versus hospital fibrinolytic therapy using automated versus cardiologist electrocardiographic diagnosis of myocardial infarction: abortion of myocardial infarction and unjustified fibrinolytic therapy
    Evert J P Lamfers
    Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
    Am Heart J 147:509-15. 2004
    ..Both have the absence of a significant rise in cardiac enzymes in common. In aborted myocardial infarction, this is a result of timely reperfusion; in unjustified thrombolysis, this is the result of an incorrect diagnosis...
  18. doi request reprint Sustained coronary patency after fibrinolytic therapy as independent predictor of 10-year cardiac survival Observations from the Antithrombotics in the Prevention of Reocclusion in COronary Thrombolysis (APRICOT) trial
    Marc A Brouwer
    Heartcenter, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Am Heart J 155:1039-46. 2008
    ..We therefore studied the impact of 3-month coronary patency after successful fibrinolysis on 10-year cardiac survival...
  19. pmc Improved clinical outcome after invasive management of patients with recent myocardial infarction and proven myocardial viability: primary results of a randomized controlled trial (VIAMI-trial)
    Ramon B van Loon
    Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands
    Trials 13:1. 2012
    ..Therefore, an invasive strategy with PCI of the infarct-related coronary artery in patients with viability would reduce the occurrence of a composite end point of death, reinfarction, or unstable angina (UA)...
  20. ncbi request reprint Pre-hospital triage for primary angioplasty: direct referral to the intervention center versus interhospital transport
    Hendrik Jan Dieker
    Department of Cardiology, Heart Lung Center, Radboud University Medical Center, Nijmegen, The Netherlands
    JACC Cardiovasc Interv 3:705-11. 2010
    ..We sought to study the impact of direct referral to an intervention center after pre-hospital diagnosis of ST-segment elevation myocardial infarction (STEMI) on treatment intervals and outcome...
  21. doi request reprint Prognostic value of free plasma homocysteine levels in patients hospitalized with acute coronary syndrome
    Martijn G H van Oijen
    Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Am J Cardiol 102:135-9. 2008
    ..11 micromol/L are a significant and independent risk factor for recurrent cardiovascular events in patients hospitalized for ACS, although total plasma homocysteine levels have no predictive value...
  22. doi request reprint The value of N-terminal proB-type natriuretic peptide for early identification of myocardial infarction in patients with high-risk non-ST-elevation acute coronary syndromes
    Robert K Riezebos
    Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Clin Chem Lab Med 49:1359-65. 2011
    ..As necrosis occurs after prolonged ischemia, a rise in NT-proBNP concentration could precede a rise in markers of necrosis...
  23. doi request reprint Aspirin versus vitamin K antagonist treatment guided by transoesophageal echocardiography in patients with atrial fibrillation: a pilot study
    Trang Dinh
    Department of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands
    Heart 100:563-8. 2014
    ..Current stroke risk schemes need improvement of predictive value in patients with atrial fibrillation. Transoesophageal echocardiography (TEE) may facilitate stroke risk assessment in such patients and guide antithrombotic treatment...
  24. ncbi request reprint The biochemical aspects of a non-ST-segment elevation acute coronary syndrome
    Robert K Riezebos
    Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Rev Cardiovasc Med 13:e70-6. 2012
    ..Assessing combinations of pathobiologically diverse biomarkers may provide a better risk evaluation method and further dictate subsequent therapy...
  25. doi request reprint Concomitant use of clopidogrel and proton pump inhibitors: impact on platelet function and clinical outcome- a systematic review
    Jeroen Jaspers Focks
    Radboud University Nijmegen Medical Center, Department of Cardiology, Nijmegen, The Netherlands
    Heart 99:520-7. 2013
    ..Despite corroborating data from retrospective studies, new clinical data fuel the controversy on this issue...
  26. ncbi request reprint Safety of the combination of intensive cholesterol-lowering therapy with oral anticoagulation medication in elderly patients with atrial fibrillation: a randomized, double-blind, placebo-controlled study
    Morteza Enajat
    Heart Centre, St Radboud University Medical Centre, Nijmegen, The Netherlands
    Drugs Aging 26:585-93. 2009
    ..The incidence of atrial fibrillation (AF) is very high in the elderly, and often oral anticoagulation (OAC) is indicated to prevent thromboembolism...
  27. ncbi request reprint High-grade infarct-related stenosis after successful thrombolysis: strong predictor of reocclusion, but not of clinical reinfarction
    Peter C Kievit
    Heartcenter, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Am Heart J 148:826-33. 2004
    ..This study investigates whether the increased risk for reocclusion associated with a high-grade lesion translates into impaired clinical outcome...
  28. ncbi request reprint Pretreatment with oral anticoagulants decreases platelet activation in patients before and after percutaneous coronary intervention
    Jurrien M ten Berg
    Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands
    Thromb Haemost 88:924-30. 2002
    ..This result may suggest a direct effect of oral anticoagulants on platelet activation...
  29. doi request reprint Peptic ulcerations are related to systemic rather than local effects of low-dose aspirin
    Martijn G H van Oijen
    Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Clin Gastroenterol Hepatol 6:309-13. 2008
    ..The aim of the study was to investigate the incidence of peptic ulcers in a population-based cohort using bioequivalent low-dose acetylsalicylic acid (80 mg) or effervescent calcium carbasalate (100 mg)...
  30. ncbi request reprint Influence of prehospital administration of aspirin and heparin on initial patency of the infarct-related artery in patients with acute ST elevation myocardial infarction
    Felix Zijlstra
    Department of Cardiology, Isala Klinieken lokatie de Weezenlanden, Groot Wezenland 20, 8011 JW Zwolle, The Netherlands
    J Am Coll Cardiol 39:1733-7. 2002
    ..The aim of this study was to investigate the influence of prehospital administration of aspirin and heparin on the initial patency of the infarct-related artery (IRA) in patients with acute myocardial infarction (MI)...
  31. ncbi request reprint Transport for abciximab facilitated primary angioplasty versus on-site thrombolysis with a liberal rescue policy: the randomised Holland Infarction Study (HIS)
    Hendrik Jan Dieker
    Department of Cardiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Thromb Thrombolysis 22:39-45. 2006
    ....
  32. ncbi request reprint Hyperhomocysteinaemia and vitamin B12 deficiency: the long-term effects in cardiovascular disease
    Martijn G H van Oijen
    Department of Gastroenterology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Cardiology 107:57-62. 2007
    ..An elevated plasma homocysteine level is an established risk factor for cardiovascular disease. Vitamin B12 plays a key role in homocysteine metabolism and could be the main factor in causing cardiovascular disease as well...
  33. pmc Polymorphisms in genes encoding acetylsalicylic acid metabolizing enzymes are unrelated to upper gastrointestinal health in cardiovascular patients on acetylsalicylic acid
    Martijn G H van Oijen
    Department of Gastroenterology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Br J Clin Pharmacol 60:623-8. 2005
    ....
  34. ncbi request reprint Normal values of pulmonary capillary wedge pressure and the blood pressure response to the Valsalva manoeuvre in healthy elderly subjects
    Jaap J Remmen
    Department of Geriatric Medicine, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Clin Physiol Funct Imaging 25:318-26. 2005
    ..The Valsalva manoeuvre showed significant discriminatory power in the detection of elevated PCWP, which underscores its potential in the non-invasive diagnosis of heart failure...
  35. ncbi request reprint Association of aspirin use with vitamin B12 deficiency (results of the BACH study)
    Martijn G H van Oijen
    Department of Gastroenterology, Heartcenter, University Medical Center, Nijmegen, The Netherlands
    Am J Cardiol 94:975-7. 2004
    ..02). Fifty-one percent of the patients were infected with H. pylori, and fewer infected patients were vitamin B(12) deficient...
  36. ncbi request reprint [Myocardial infarction aborted by rapid percutaneous coronary intervention]
    Jeroen van Etten
    Onze Lieve Vrouwe Gasthuis, afd Cardiologie, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 153:A467. 2009
    ..Nevertheless, the results of the 2 cases discussed in our article are promising...
  37. ncbi request reprint Gastric status and vitamin B12 levels in cardiovascular patients
    Martijn G H van Oijen
    Department of Medicine, Division of Gastroenterology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Dig Dis Sci 52:2186-9. 2007
    ..Of the remaining patients, five (2%) had ACG. Deficiency of vitamin B12 is common among subjects with coronary heart disease. Up to 20% of these deficiencies are related to ACG...
  38. doi request reprint Triggering mechanisms of stent thrombosis
    Bastiaan Zwart
    Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands
    EuroIntervention 6:722-8. 2011
    ..The aim of this study was to determine the role of potential triggers of stent thrombosis...
  39. ncbi request reprint Oral anticoagulation for acute coronary syndromes
    Marc A Brouwer
    Heartcenter, Department of Cardiology, University Medical Center Nijmegen, The Netherlands
    Circulation 105:1270-4. 2002
  40. pmc Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease
    Frank F Willems
    Department of Cardiology, Rijnstate Hospital, PO Box 9555, Arnhem, 6800 TA, The Netherlands
    Br J Pharmacol 141:825-30. 2004
    ..Detrimental effects of the storage of high levels of the non-natural isomer 6[R] 5-MTHF cannot be excluded...
  41. ncbi request reprint Low-dose aspirin for primary prevention of cardiovascular disease
    Sebastian J H Bredie
    Department of Medicine, University Medical Center St Radboud, Nijmegen, The Netherlands
    Semin Vasc Med 3:177-84. 2003
    ..Notwithstanding these results, for each patient it remains essential to balance the cardiovascular risk profile against the small increased risk of bleeding complications when prescribing aspirin...
  42. ncbi request reprint Both antiplatelet and anticoagulant therapy may favorably affect outcome in patients with advanced heart failure. A retrospective analysis of the PRIME-II trial
    Rudolf A de Boer
    Department of Cardiology, University Hospital Groningen, P O Box 30 001, 9700 RM, Groningen, The Netherlands
    Thromb Res 116:279-85. 2005
    ..We performed a post-hoc analysis to evaluate the effect of the use of anti-thrombotic therapy with APT and OAC...
  43. ncbi request reprint Reperfusion therapy in out-of-hospital cardiac arrest: current insights
    Wessel Keuper
    Radboud University Nijmegen Medical Centre, Department of Cardiology, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands
    Resuscitation 73:189-201. 2007
    ..In this review, the rationale, safety and efficacy of reperfusion therapy in patients with out-of-hospital cardiac arrest will be discussed...
  44. ncbi request reprint Familial sudden death is an important risk factor for primary ventricular fibrillation: a case-control study in acute myocardial infarction patients
    Lukas R C Dekker
    Department of Cardiology, B2 116, Academic Medical Center, PO Box 22660, 1100 DD, Amsterdam, The Netherlands
    Circulation 114:1140-5. 2006
    ..Primary ventricular fibrillation (VF) accounts for the majority of deaths during the acute phase of myocardial infarction. Identification of patients at risk for primary VF remains very poor...
  45. doi request reprint Molecular and cellular basis for diastolic dysfunction
    Loek van Heerebeek
    Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Curr Heart Fail Rep 9:293-302. 2012
    ....
  46. doi request reprint Low myocardial protein kinase G activity in heart failure with preserved ejection fraction
    Loek van Heerebeek
    Department of Physiology, Cardiology, Pathology, and Surgery, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Circulation 126:830-9. 2012
    ..To discern altered control of myocardial remodeling by PKG, HFPEF was compared with aortic stenosis and HF with reduced EF (HFREF)...
  47. doi request reprint Long-term anticoagulation in patients with coronary disease, and future developments
    Freek W A Verheugt
    Department of Cardiology, HeartLung Center, University Medical Center, Nijmegen, The Netherlands
    Curr Opin Cardiol 23:315-9. 2008
    ..As anticoagulant therapy is a cornerstone in the early management of acute coronary syndrome, the question remains whether long-term anticoagulation after discharge will further improve outcome...
  48. ncbi request reprint Prehospital thrombolysis with reteplase: the Nijmegen/Rotterdam study
    Evert J P Lamfers
    Department of Cardiology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
    Am Heart J 146:479-83. 2003
    ....
  49. ncbi request reprint The lady aspirin for cardiovascular disease
    Freek W A Verheugt
    Department of Cardiology, Heartcentre, University Medical Centre, Nijmegen, Netherlands
    Lancet 366:1148-50. 2005
  50. doi request reprint Percutaneous coronary intervention for non ST-elevation acute coronary syndromes: which, when and how?
    Robert K Riezebos
    Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Am J Cardiol 107:509-15. 2011
    ..In conclusion, patients presenting with non-ST elevation acute coronary syndromes constitute a very diverse population; diagnostic workup, treatment, and the timing of a possible intervention should be tailored individually...
  51. ncbi request reprint N-terminal pro-brain natriuretic peptide for additional risk stratification in patients with non-ST-elevation acute coronary syndrome and an elevated troponin T: an Invasive versus Conservative Treatment in Unstable coronary Syndromes (ICTUS) substudy
    Fons Windhausen
    Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
    Am Heart J 153:485-92. 2007
    ....
  52. ncbi request reprint Effects of furosemide versus captopril on postprandial and orthostatic blood pressure and on cerebral oxygenation in patients > or = 70 years of age with heart failure
    D Jannet Mehagnoul-Schipper
    Department of Geriatric Medicine, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Am J Cardiol 90:596-600. 2002
    ..25 mg and 2-week treatment with furosemide 40 mg once daily or captopril 12.5 mg twice daily. These findings indicate that initiating furosemide treatment worsens PPH, and furosemide is less safe in elderly patients with heart failure...
  53. ncbi request reprint Aborted myocardial infarction: a new target for reperfusion therapy
    Freek W A Verheugt
    Heartcenter, Department of Cardiology, University Medical Center, St Radboud, Nijmegen, The Netherlands
    Eur Heart J 27:901-4. 2006
    ..Given that mortality, re-infarction, and stroke are declining in incidence, we suggest the introduction of aborted infarction as an endpoint in clinical trials of ST-elevation acute coronary syndromes...
  54. pmc Sympathoinhibitory effect of statins in chronic heart failure
    Marc E Gomes
    Department of Cardiology, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Clin Auton Res 20:73-8. 2010
    ..Animal studies suggest that statin therapy can reduce central sympathetic outflow. This study assessed statin effects on (central) sympathetic activity in human chronic heart failure (CHF) patients...
  55. ncbi request reprint Analysis of mortality within the first six months after coronary reoperation
    Frans M van Eck
    Department of Thoracic and Cardiac Surgery, Heart Center, University of Nijmegen Medical Center, St Radboud, Nijmegen, The Netherlands
    Ann Thorac Surg 74:2106-12. 2002
    ..Identify risk factors associated with mortality following repeat coronary revascularization (redoCABG) within the first 6 months following surgery...
  56. ncbi request reprint Troponin I release at rest and after exercise in patients with hypertrophic cardiomyopathy and the effect of betablockade
    Gheorghe A M Pop
    Heartcenter, Radboud University Medical Centre, Nijmegen, The Netherlands
    Arch Cardiol Mex 76:415-8. 2006
    ..We detected elevated troponin levels in some of these patients and hypothesized that troponin release would rise after exercise and diminish after betablockade...
  57. ncbi request reprint High-dose aspirin in addition to daily low-dose aspirin decreases platelet activation in patients before and after percutaneous coronary intervention
    Jurrien M ten Berg
    Department of Cardiology, St Antonius Hospital Nieuwegein, Koekoekslaan 1, Nieuwegein 3435 CM, The Netherlands
    Thromb Res 105:385-90. 2002
    ..Activated platelets play a major role in acute vessel closure after coronary angioplasty. Although aspirin is the routine therapy during angioplasty, it only incompletely prevents acute closure. This might be due to suboptimal dosing...
  58. ncbi request reprint Finapres arterial pulse wave analysis with Modelflow is not a reliable non-invasive method for assessment of cardiac output
    Jaap J Remmen
    Department of Geriatric Medicine, Heartcenter, Department of Cardiology, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Clin Sci (Lond) 103:143-9. 2002
    ..Although simple, non-invasive and patient-friendly, the Modelflow method is inaccurate for assessment of cardiac output without invasive calibration...
  59. ncbi request reprint Coronary endothelial function in hyperhomocysteinemia: improvement after treatment with folic acid and cobalamin in patients with coronary artery disease
    Frank F Willems
    Department of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands
    J Am Coll Cardiol 40:766-72. 2002
    ..We evaluated the effect of therapy with folic acid and cobalamin on coronary endothelial function, expressed as a change in volumetric coronary blood flow (CBF), in hyperhomocysteinemic patients with coronary artery disease (CAD)...
  60. ncbi request reprint Hotline sessions of the 26th European Congress of Cardiology
    Stefanie Schellekens
    Department of Cardiology, University Medical Centre Nijmegen, St Radboud, Heartcentre, 540 Cardiology, P O Box 9101, 6500 Nijmegen HB, The Netherlands
    Eur Heart J 25:2164-6. 2004