Research Topics
| H B UylingsSummaryAffiliation: Netherlands Institute of Ecology Country: The Netherlands Publications
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Detail Information
Publications
Morphology of neuropeptide Y-immunoreactive neurons and fibers in human prefrontal cortex during prenatal and postnatal developmentH B Uylings
Graduate School for the Neurosciences, Netherlands Institute for Brain Research, Amsterdam, The Netherlands
J Comp Neurol 379:523-40. 1997..Unlike the NPY-ir subplate neurons, the general development of cortical NPY-ir neurons did not show an obvious decline in neuronal size and was similar to the pattern in Golgi-staining...- Left-right asymmetry in volume and number of neurons in adult Broca's areaHarry B M Uylings
Netherlands Institute for Brain Research, Royal Netherlands Academy of Arts and Sciences, Amsterdam
Cortex 42:652-8. 2006..In addition, it shows that the inter-individual variability was also very large (more than twofold) in the numerical values of all variables... - Measures for quantifying dendritic arborizationsHarry B M Uylings
Netherlands Institute for Brain Research, Graduate School Neurosciences Amsterdam
Network 13:397-414. 2002..These measures are applied to differentiate and classify groups of neurons. They are also of importance for simulation or reconstruction of neuronal trees in view of functional computational characteristics... - No postnatal doubling of number of neurons in human Broca's areas (Brodmann areas 44 and 45)? A stereological studyH B M Uylings
Netherlands Institute for Brain Research, Graduate School Neurosciences Amsterdam, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
Neuroscience 136:715-28. 2005..No major asymmetry in total number of neurons in BA 44 and 45 was detected... - Neuronal changes in normal human aging and Alzheimer's diseaseHarry B M Uylings
Netherlands Institute for Brain Research, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
Brain Cogn 49:268-76. 2002..This review concludes that the association cortices in particular are affected in aging and Alzheimer's disease and that the primary visual and somatosensory cortices are relatively spared... - Consequences of large interindividual variability for human brain atlases: converging macroscopical imaging and microscopical neuroanatomyH B M Uylings
Netherlands Institute for Brain Research, Graduate School Neurosciences Amsterdam, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 33, Amsterdam, AZ, 1105 The Netherlands
Anat Embryol (Berl) 210:423-31. 2005..In addition, we will briefly discuss the different 'Brodmann' nomenclatures which are in use for the cerebral cortex... - Do rats have a prefrontal cortex?Harry B M Uylings
Netherlands Institute for Brain Research, KNAW, Graduate School Neurosciences, Meibergdreef 33, 1105 AZ, Amsterdam, The Netherlands
Behav Brain Res 146:3-17. 2003..We will argue that rats have a functionally divided prefrontal cortex that includes not only features of the medial and orbital areas in primates, but also some features of the primate dorsolateral prefrontal cortex... - Development of the cerebral cortex in rodents and manH B Uylings
Netherlands Institute for Brain Research, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands
Eur J Morphol 38:309-12. 2000..In this short review the present vistas on neuronal generation and migration, and the occurrence of transient layers are summarized... - The early differentiation of the neocortex: a hypothesis on neocortical evolutionH Super
Graduate School of Neurosciences Amsterdam, Department of Visual System Analysis, AMC, University of Amsterdam, PO Box 12011, 1100 AA Amsterdam, The Netherlands
Cereb Cortex 11:1101-9. 2001.... - Neuropsychology of infarctions in the thalamus: a reviewY D Van Der Werf
Graduate School for Neurosciences, Amsterdam, The Netherlands
Neuropsychologia 38:613-27. 2000..The results indicate that damage to the mediodorsal nucleus of the thalamus, the midline nuclei or the intralaminar nuclei, or a combined lesion of these structures may be responsible for deficits of executive functioning... - Retrograde degeneration of thalamic neurons in the mediodorsal nucleus after neonatal and adult aspiration lesions of the medial prefrontal cortex in the rat. Implications for mechanisms of functional recoveryC G van Eden
Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research
Eur J Neurosci 10:1581-9. 1998..These findings are discussed in the light of the previously proposed role of the thalamus as a neural substrate of functional sparing after neonatal cortical lesions... - Natural variability in the number of dendritic segments: model-based inferences about branching during neurite outgrowthJ Van Pelt
Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research
J Comp Neurol 387:325-40. 1997..The branching probability of a terminal segment was found to be in the order of 0.002 per hour in the first 4 weeks postnatal with a 5-fold transient increase in the second week... - Thalamic volume predicts performance on tests of cognitive speed and decreases in healthy aging. A magnetic resonance imaging-based volumetric analysisY D Van Der Werf
Graduate School for Neurosciences Amsterdam, Amsterdam, The Netherlands
Brain Res Cogn Brain Res 11:377-85. 2001..Additionally, in young and middle-aged, but not in old subjects, the size of the thalamus predicted performance on tasks that require cognitive speed... - The need for integrating neuronal morphology databases and computational environments in exploring neuronal structure and functionJ Van Pelt
Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research
Anat Embryol (Berl) 204:255-65. 2001..Additionally, one of the dendritic modeling approaches is described in more detail in the Appendix... - Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing corticosteroid regimensJoão J Cerqueira
Life and Health Sciences Research Institute Instituto de Investigação em ciências da vida e da saúde, School of Health Sciences, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
Cereb Cortex 17:1998-2006. 2007..None of the treatments influenced the architecture of the basal dendrites. These results add to our knowledge of the morphological substrates through which corticosteroids may disrupt mPFC-dependent behaviors... - Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorderPeter L Remijnse
Department of Psychiatry, VU University Medical Center, Graduate School of Neurosciences, and Outpatient Academic Clinic for Anxiety Disorders, GGZ Buitenamstel, Amsterdam, The Netherlands
Arch Gen Psychiatry 63:1225-36. 2006..However, the engagement of this neural loop in OCD has not been tested directly in a cognitive activation imaging paradigm so far... - Lifespan alterations of basal dendritic trees of pyramidal neurons in the human prefrontal cortex: a layer-specific patternZdravko Petanjek
Department of Neuroscience, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Salata 12, 10000 Zagreb, Croatia
Cereb Cortex 18:915-29. 2008..These structural changes occurred during both the period of rapid cognitive development in preschool children and the period of protracted cognitive maturation during the childhood, puberty, and adolescence... 
Medial prefrontal serotonin in the rat is involved in goal-directed behaviour when affect guides decision makingGeoffrey Van der Plasse
Netherlands Institute for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA, Amsterdam, ZO, The Netherlands
Psychopharmacology (Berl) 195:435-49. 2007..g. information with an 'emotional' content). While recent work has explored the specific role of the orbital PFC herein, the role of the medial PFC remains unclear...
The rat orbital and agranular insular prefrontal cortical areas: a cytoarchitectonic and chemoarchitectonic studyHenri J J M Van De Werd
Department of Anatomy and Neuroscience, VU University Medical Center, Graduate School Neuroscience Amsterdam, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
Brain Struct Funct 212:387-401. 2008..The posterior part of VLO has a different structure and is, therefore, indicated as VLOp (VLO, posterior part)...- The orbital cortex in rats topographically projects to central parts of the caudate-putamen complexEduardo A Schilman
Department of Anatomy and Neurosciences, Institute for Clinical and Experimental Neurosciences, Graduate School Neuroscience Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
Neurosci Lett 432:40-5. 2008..In contrast to nonhuman primates, the remainder of the rat nucleus accumbens is virtually free of orbital projections... - Neural correlates of a reversal learning task with an affectively neutral baseline: an event-related fMRI studyPeter L Remijnse
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
Neuroimage 26:609-18. 2005..These results extend our understanding of the neural substrate of reversal learning in humans... - Distributions of transmitter receptors in the macaque cingulate cortexAhmet Bozkurt
C. and O. Vogt Brain Research Institute, Heinrich Heine University, , Germany
Neuroimage 25:219-29. 2005.... - Branching rates and growth functions in the outgrowth of dendritic branching patternsJaap van Pelt
Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research
Network 13:261-81. 2002..It is shown that the baseline branching rate is a rapidly decreasing function of time, indicating the largest baseline drive for branching in the early days of outgrowth... - Regional frontal cortical volumes decrease differentially in aging: an MRI study to compare volumetric approaches and voxel-based morphometryDanielle J Tisserand
Brain and Behaviour Institute, Maastricht University, 6229 GP Maastricht, The Netherlands
Neuroimage 17:657-69. 2002..Overall, it was concluded that although semiautomated and voxel-based methods can provide a reasonable estimate of regional brain volume, they cannot serve as a substitute for manual volumetry... - Glial cell loss in the anterior cingulate cortex, a subregion of the prefrontal cortex, in subjects with schizophreniaAnette K Stark
Research Laboratory for Stereology and Neuroscience, Bispebjerg Hospital, Bispebjerg Bakke, 2400 Copenhagen NV, Denmark
Am J Psychiatry 161:882-8. 2004.... - Cellular changes in the postmortem hippocampus in major depressionCraig A Stockmeier
Department of Psychiatry and Human Behavior Box 127, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Biol Psychiatry 56:640-50. 2004..Imaging studies report that hippocampal volume is decreased in major depressive disorder (MDD). A cellular basis for reduced hippocampal volume in MDD has not been identified... - Random or selective neuroanatomical connectivity. Study of the distribution of fibers over two populations of identified interneurons in cerebral cortexMarjolein Vinkenoog
Graduate School Neurosciences Amsterdam, Research Institute for Neurosciences Vrije Universiteit Medical Center, Department of Anatomy, MF-G-136, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Brain Res Brain Res Protoc 14:67-76. 2005..The present approach can be used to examine whether or not a particular class of chemically identified neurons receives preferential innervation by a particular fiber projection... - Gender-related changes in increase of dopaminergic neurons in the olfactory bulb of Parkinson's disease patientsEvelien Huisman
Department of Anatomy and Neurosciences, VU University Medical Center, Amsterdam, The Netherlands
Mov Disord 23:1407-13. 2008..We therefore conclude that the hyposmia in Parkinson's disease patients cannot simply be ascribed to dopamine in the olfactory bulb... - The prefrontal cortex in the Göttingen minipig brain defined by neural projection criteria and cytoarchitectureJacob Jelsing
Research Laboratory for Stereology and Neuroscience, Copenhagen University Hospital, Bispebjerg, Bispebjerg Bakke 23, 2400 Copenhagen, Denmark
Brain Res Bull 70:322-36. 2006..Stereological estimates of PFC volume showed that the Göttingen minipig PFC constitutes about 24% of the total neocortex volume and 10% of the total brain volume... - Differential regional atrophy of the cingulate gyrus in Alzheimer disease: a volumetric MRI studyBethany F Jones
Department of Neurology, VU University Medical Centre, Amsterdam, The Netherlands
Cereb Cortex 16:1701-8. 2006.... - Contributions of thalamic nuclei to declarative memory functioningYsbrand D Van Der Werf
Dept of Psychology, Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, Montreal, Canada
Cortex 39:1047-62. 2003..The two types of function subserved by these groups of thalamic nuclei, focussing on contents vs. state, need to work in parallel to mediate and allow memory functioning, respectively... - Decreased thalamic expression of the homeobox gene DLX1 in psychosisMarjan Kromkamp
Department of Pharmacology, Rudolf Magnus Institute for Neurosciences, University Medical Center, Utrecht, The Netherlands
Arch Gen Psychiatry 60:869-74. 2003..CONCLUSION: Decreased thalamic expression of DLX1 in schizophrenia and bipolar disorder with psychosis suggests shared genetic deficits in expression of this homeobox gene... - Cerebral blood flow changes during script-driven imagery in police officers with posttraumatic stress disorderRamón J L Lindauer
Centre for Psychological Trauma, Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Biol Psychiatry 56:853-61. 2004..The aim of this study was to examine the neuronal circuitry underlying responses to script-driven imagery in traumatized police officers with and without PTSD and with low comorbidity rates... - About assumptions in estimation of density of neurons and glial cellsHarry B M Uylings
Biol Psychiatry 51:840-2; author reply, 842-6. 2002