Rachel M Stenger

Summary

Affiliation: Netherlands Vaccine Institute
Country: The Netherlands

Publications

  1. ncbi Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation
    Annemieke M H Boots
    NV Organon, Research Laboratories, Oss, The Netherlands
    Arthritis Res Ther 9:R71. 2007
  2. ncbi Immunodominance in mouse and human CD4+ T-cell responses specific for the Bordetella pertussis virulence factor P.69 pertactin
    Rachel M Stenger
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven
    Infect Immun 77:896-903. 2009
  3. ncbi Impaired long-term maintenance and function of Bordetella pertussis specific B cell memory
    Rachel M Stenger
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven, The Netherlands
    Vaccine 28:6637-46. 2010
  4. ncbi Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis
    Floris Fransen
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven, The Netherlands
    PLoS ONE 5:e15692. 2010
  5. ncbi Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens
    Rachel M Stenger
    Laboratory of Vaccine Research, Unit for Vaccinology, National Institute for Public Health and the Environment, Bilthoven, Netherlands
    Clin Vaccine Immunol 18:595-603. 2011

Collaborators

  • Peter van der Ley
  • Frits R Mooi
  • Floris Fransen
  • Audrey J King
  • Annemieke M H Boots
  • Henk Hubers
  • Marie-jose C van Lierop
  • Milou Kouwijzer
  • Bernice M Westrek-Esselink
  • Cindy van Doorn
  • Ebo S Bos
  • Marie jose C van Lierop
  • Leontien den Hoed-van Zandbrink
  • Gijs F Verheijden
  • Cornelis M Timmers
  • Catharina J van Staveren

Detail Information

Publications5

  1. ncbi Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263-275) epitope: an MHC anchor variant peptide for immune modulation
    Annemieke M H Boots
    NV Organon, Research Laboratories, Oss, The Netherlands
    Arthritis Res Ther 9:R71. 2007
    ..We identified a non-classical APL by modification of the p1 MHC anchor in a synovial auto-epitope. This APL may qualify for rheumatoid arthritis immunotherapy...
  2. ncbi Immunodominance in mouse and human CD4+ T-cell responses specific for the Bordetella pertussis virulence factor P.69 pertactin
    Rachel M Stenger
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven
    Infect Immun 77:896-903. 2009
    ..Thus, it may provide a useful tool for the evaluation of the type, magnitude, and maintenance of B. pertussis-specific CD4(+) T-cell mechanisms in preclinical and clinical vaccine studies...
  3. ncbi Impaired long-term maintenance and function of Bordetella pertussis specific B cell memory
    Rachel M Stenger
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven, The Netherlands
    Vaccine 28:6637-46. 2010
    ..A better understanding of the mechanisms of limited immunological memory to pertussis may help to improve current vaccines...
  4. ncbi Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis
    Floris Fransen
    Laboratory of Vaccine Research, Netherlands Vaccine Institute, Bilthoven, The Netherlands
    PLoS ONE 5:e15692. 2010
    ..Together our data demonstrate that TLR4 activation contributes to the immunogenicity of the N. meningitidis OMV vaccine and the whole cell pertussis vaccine, but that TLR2 activation is not required...
  5. ncbi Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens
    Rachel M Stenger
    Laboratory of Vaccine Research, Unit for Vaccinology, National Institute for Public Health and the Environment, Bilthoven, Netherlands
    Clin Vaccine Immunol 18:595-603. 2011
    ..We conclude that the hexaplex mouse DTP MIA is a specific, sensitive, and high-throughput alternative for ELISA to investigate the quantity and quality of serological responses to DTP antigens in preclinical vaccine studies...