E J G Dubelaar

Summary

Affiliation: Netherlands Institute of Ecology
Country: The Netherlands

Publications

  1. ncbi ApoE epsilon4 genotype is accompanied by lower metabolic activity in nucleus basalis of Meynert neurons in Alzheimer patients and controls as indicated by the size of the Golgi apparatus
    E J G Dubelaar
    Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    J Neuropathol Exp Neurol 63:159-69. 2004
  2. ncbi Post-mortem brain tissue cultures from elderly control subjects and patients with a neurodegenerative disease
    R W H Verwer
    Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
    Exp Gerontol 38:167-72. 2003
  3. ncbi Therapeutic strategies for Alzheimer disease: focus on neuronal reactivation of metabolically impaired neurons
    D F Swaab
    Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    Alzheimer Dis Assoc Disord 17:S114-22. 2003
  4. ncbi Brain aging and Alzheimer's disease; use it or lose it
    D F Swaab
    Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
    Prog Brain Res 138:343-73. 2002
  5. ncbi Tissue cultures from adult human postmortem subcortical brain areas
    R W H Verwer
    Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    J Cell Mol Med 6:429-32. 2002

Detail Information

Publications5

  1. ncbi ApoE epsilon4 genotype is accompanied by lower metabolic activity in nucleus basalis of Meynert neurons in Alzheimer patients and controls as indicated by the size of the Golgi apparatus
    E J G Dubelaar
    Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    J Neuropathol Exp Neurol 63:159-69. 2004
    ..As the disease progresses into later stages of AD (Braak V-VI) neuronal metabolism strongly diminishes, resulting in neurons with extremely small GA sizes, irrespective of APOE genotype...
  2. ncbi Post-mortem brain tissue cultures from elderly control subjects and patients with a neurodegenerative disease
    R W H Verwer
    Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
    Exp Gerontol 38:167-72. 2003
    ..and fixed or frozen postmortem brain tissue examination...
  3. ncbi Therapeutic strategies for Alzheimer disease: focus on neuronal reactivation of metabolically impaired neurons
    D F Swaab
    Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    Alzheimer Dis Assoc Disord 17:S114-22. 2003
    ..We will also discuss a procedure that has been developed to culture human postmortem brain tissue, which allows testing of the efficacy of putative stimulatory compounds...
  4. ncbi Brain aging and Alzheimer's disease; use it or lose it
    D F Swaab
    Netherlands Institute for Brain Research, Meibergdreef 33, 1105 AZ Amsterdam, The Netherlands
    Prog Brain Res 138:343-73. 2002
    ..A procedure has been developed to culture human postmortem brain tissue that allows testing of the efficacy of putative stimulatory compounds such as neurotrophins...
  5. ncbi Tissue cultures from adult human postmortem subcortical brain areas
    R W H Verwer
    Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research, Amsterdam, The Netherlands
    J Cell Mol Med 6:429-32. 2002
    ..Such cultures may enable us to study age and disease related processes directly in human brain tissue. Here, we present observations on subcortical brain tissue...