Jacqueline Deschamps

Summary

Affiliation: Netherlands Institute of Ecology
Country: The Netherlands

Publications

  1. ncbi request reprint Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation
    Eric van den Akker
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 129:2181-93. 2002
  2. ncbi request reprint Initiation, establishment and maintenance of Hox gene expression patterns in the mouse
    J Deschamps
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht
    Int J Dev Biol 43:635-50. 1999
  3. ncbi request reprint Developmental regulation of the Hox genes during axial morphogenesis in the mouse
    Jacqueline Deschamps
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 132:2931-42. 2005
  4. ncbi request reprint Developmental biology. Hox genes in the limb: a play in two acts
    Jacqueline Deschamps
    Hubrecht Laboratory, Uppsalalaan 8, 3584CT Utrecht, Netherlands
    Science 304:1610-1. 2004
  5. ncbi request reprint Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes
    E van den Akker
    Hubrecht Laboratory, The Netherlands Institute for Developmental Biology, Uppsalalaan 8, Utrecht, The Netherlands
    Development 128:1911-21. 2001
  6. ncbi request reprint Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence
    Carina van Rooijen
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, and University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Development 139:2576-83. 2012
  7. doi request reprint Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone
    Cesca van de Ven
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Utrecht, The Netherlands
    Development 138:3451-62. 2011
  8. doi request reprint Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos
    Teddy Young
    Hubrecht Institute KNAW and University Medical Center, 3584 CT Utrecht, The Netherlands
    Dev Cell 17:516-26. 2009
  9. ncbi request reprint Acquisition of Hox codes during gastrulation and axial elongation in the mouse embryo
    Sylvie Forlani
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 130:3807-19. 2003
  10. pmc Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants
    Wim d Graaff
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3485 CT Utrecht, The Netherlands
    Proc Natl Acad Sci U S A 100:13362-7. 2003

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation
    Eric van den Akker
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 129:2181-93. 2002
    ..The function of Cdx genes in morphogenetic processes during gastrulation and tail bud extension, and their relationship with the Hox genes are discussed in the light of available data in Amphioxus, C. elegans, Drosophila and mice...
  2. ncbi request reprint Initiation, establishment and maintenance of Hox gene expression patterns in the mouse
    J Deschamps
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht
    Int J Dev Biol 43:635-50. 1999
    ....
  3. ncbi request reprint Developmental regulation of the Hox genes during axial morphogenesis in the mouse
    Jacqueline Deschamps
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 132:2931-42. 2005
    ..In particular, we highlight the integration of these transducers of anteroposterior positional information into the genetic network that drives tissue generation and patterning during axial elongation...
  4. ncbi request reprint Developmental biology. Hox genes in the limb: a play in two acts
    Jacqueline Deschamps
    Hubrecht Laboratory, Uppsalalaan 8, 3584CT Utrecht, Netherlands
    Science 304:1610-1. 2004
  5. ncbi request reprint Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes
    E van den Akker
    Hubrecht Laboratory, The Netherlands Institute for Developmental Biology, Uppsalalaan 8, Utrecht, The Netherlands
    Development 128:1911-21. 2001
    ..We conclude that paralogous Hox genes can have a unique role in patterning specific axial regions in addition to their redundant function at other AP levels...
  6. ncbi request reprint Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence
    Carina van Rooijen
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, and University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Development 139:2576-83. 2012
    ..Cdx requirement for the post-head section of the axis is ancestral as it takes place in arthropods as well...
  7. doi request reprint Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone
    Cesca van de Ven
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Utrecht, The Netherlands
    Development 138:3451-62. 2011
    ..They shed a new light on the etiology of the caudal dysplasia or caudal regression range of human congenital defects...
  8. doi request reprint Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos
    Teddy Young
    Hubrecht Institute KNAW and University Medical Center, 3584 CT Utrecht, The Netherlands
    Dev Cell 17:516-26. 2009
    ..Concomitant regulation of Cyp26a1 expression, restraining retinoic acid signaling away from the posterior growth zone, may likewise play a role in timing the trunk-tail transition...
  9. ncbi request reprint Acquisition of Hox codes during gastrulation and axial elongation in the mouse embryo
    Sylvie Forlani
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Development 130:3807-19. 2003
    ....
  10. pmc Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants
    Wim d Graaff
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3485 CT Utrecht, The Netherlands
    Proc Natl Acad Sci U S A 100:13362-7. 2003
    ....
  11. ncbi request reprint The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice
    Johan van Nes
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht
    Development 133:419-28. 2006
    ..Cdx genes thus operate in a redundant way during placentogenesis, as they do during embryonic axial elongation and patterning, and independently from the previously reported early Cdx2-specific role in the trophectoderm at implantation...
  12. ncbi request reprint Expression of retinaldehyde dehydrogenase II and sequential activation of 5' Hoxb genes in the mouse caudal hindbrain
    Tony Oosterveen
    Hubrecht Laboratory, The Netherlands Institute of Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Gene Expr Patterns 4:243-7. 2004
    ..5 and E11.5 in the caudal hindbrain, and that this differential expansion occurs just rostrally to the localisation of the transcripts for the RA biosynthetic enzyme Raldh2 in the cervical mesenchyme...
  13. pmc Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain
    Tony Oosterveen
    Hubrecht Laboratory, The Netherlands Institute of Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    EMBO J 22:262-9. 2003
    ..The RARE and surrounding sequences are found at homologous positions in the human, mouse and zebrafish genome, which supports an evolutionarily conserved regulatory function...
  14. ncbi request reprint Hox cluster polarity in early transcriptional availability: a high order regulatory level of clustered Hox genes in the mouse
    Bernard A J Roelen
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
    Mech Dev 119:81-90. 2002
    ..Interestingly, Cdx1 manifested the same early transcriptional availability as Hoxb1...
  15. ncbi request reprint Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse
    Monika Bialecka
    Hubrecht Institute, Developmental Biology and Stem Cell research and UMC Utrecht, Uppsalalaan 8, 3584CT Utrecht, The Netherlands
    Dev Biol 371:227-34. 2012
    ..Since PGC residence within the posterior growth zone is a mouse-specific feature, our data suggest that mouse PGCs opportunistically became dependent on the axial progenitor niche...
  16. doi request reprint Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment
    Monika Bialecka
    Hubrecht Institute, Developmental Biology and Stem Cell Research, and Utrecht University Medical Center, Utrecht, The Netherlands
    Dev Biol 347:228-34. 2010
    ..Taken together with the data shown here, this suggests that Cdx genes function to maintain a signaling-dependent niche for the posterior axial progenitors...
  17. ncbi request reprint The direct context of a hox retinoic acid response element is crucial for its activity
    Tony Oosterveen
    Hubrecht Laboratory, The Netherlands Institute of Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    J Biol Chem 278:24103-7. 2003
    ..We suggest that the context of RARE motifs is important for the distinct transcriptional activities of genes under control of retinoid signaling...
  18. ncbi request reprint Hox, Cdx, and anteroposterior patterning in the mouse embryo
    Teddy Young
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan, Utrecht, The Netherlands
    Curr Top Dev Biol 88:235-55. 2009
    ..We also touch on the unanswered question whether vertebrate Cdx gene expression delivers A-P positional information in its own right, as Caudal does in Drosophila, or whether it does so exclusively by upregulating Hox genes...
  19. pmc Tailored Hox gene transcription and the making of the thumb
    Jacqueline Deschamps
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Utrecht 3584 CT, The Netherlands
    Genes Dev 22:293-6. 2008
  20. ncbi request reprint Region-specific regulation of posterior axial elongation during vertebrate embryogenesis
    Roel Neijts
    Hubrecht Institute and University Medical Center, Utrecht, The Netherlands
    Dev Dyn 243:88-98. 2014
    ..The underlying processes have been shown to be disrupted in mouse mutants, some of which were described more than half a century ago...
  21. ncbi request reprint Ancestral and recently recruited global control of the Hox genes in development
    Jacqueline Deschamps
    Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    Curr Opin Genet Dev 17:422-7. 2007
    ..Several of such novel global regulatory circuits have recently been characterised at the molecular genetic level in the mouse...
  22. pmc Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice
    Jan C Holstege
    Department of Neuroscience, Erasmus Medical Center, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Proc Natl Acad Sci U S A 105:6338-43. 2008
    ..The data therefore suggest that a lower number of neurons in the upper spinal laminae and neuronal disorganization in the dorsal horn underlie the sensory defects including the excessive grooming of the Hoxb8 mutant...
  23. ncbi request reprint Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8
    Yu ichi Fujimura
    RIKEN Research Center for Allergy and Immunology, 1 7 22 Suehiro, Tsurumi ku, Yokohama 230 0045, Japan
    Development 133:2371-81. 2006
    ..The present study indicates distinct roles for class 2 PcG complexes in transcriptionally repressed and active domains of Hoxb8 gene...
  24. ncbi request reprint Colinearity loops out
    Denis Duboule
    Department of Zoology and Animal Biology and National Program Frontiers in Genetics, University of Geneva, CH 1211 Geneva, Switzerland
    Dev Cell 6:738-40. 2004
    ..They show that, while chromatin remodeling confers transcriptional competence to the gene cluster, subsequent sequential extrusion of genes from their chromosome territory may determine their coordinated expression in time...
  25. pmc Cdx2 is essential for axial elongation in mouse development
    Kallayanee Chawengsaksophak
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5
    Proc Natl Acad Sci U S A 101:7641-5. 2004
    ..The gene appears to be important in the integration of the pathways controlling embryonic axial elongation, and anterior-posterior patterning...
  26. pmc Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
    Jan Willem Voncken
    Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 100:2468-73. 2003
    ..Importantly, this finding implicates Polycomb-mediated repression of the Cdkn2a locus in early murine development...
  27. ncbi request reprint Developmental biology: first come, first served
    Rolf Zeller
    Nature 420:138-9. 2002
  28. ncbi request reprint Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?
    Claudio D Stern
    European Union Network of Excellence Cells into Organs, University College London, UK
    Int J Dev Biol 50:3-15. 2006
    ..In this paper, we outline some of the major outstanding problems and controversies and try to identify some reasons why it has been so difficult to resolve this important issue...