W Vleeming

Summary

Affiliation: National Institute for Public Health and the Environment
Country: The Netherlands

Publications

  1. ncbi ACE inhibitor-induced angioedema. Incidence, prevention and management
    W Vleeming
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Drug Saf 18:171-88. 1998
  2. pmc Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats
    W Vleeming
    National Institute of Public Health en Environment, Laboratory of Health Effects Research, P O Box 1, NL 3720 BA Bilthoven, The Netherlands
    Br J Pharmacol 129:1801-7. 2000
  3. ncbi The role of nitric oxide in cigarette smoking and nicotine addiction
    Wim Vleeming
    National Institute of Public Health and Environment, Laboratory of Health Effects Research, PO Box 1, NL 3720 BA Bilthoven, The Netherlands
    Nicotine Tob Res 4:341-8. 2002
  4. ncbi The effect of pertussis toxin and whole-cell pertussis vaccine on haemodynamics and autonomic responsiveness in the rat depends on route of administration and age
    J G Van Amsterdam
    Laboratory of Health Effects Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Vaccine 16:666-71. 1998
  5. ncbi Subchronic inhalation of mixtures of cigarette smoke constituents in Xpa-/-p53+/- knock-out mice: a comparison of intermittent with semi-continuous exposure to acetaldehyde, formaldehyde, and acrolein
    F R Cassee
    Centre for Environmental Health Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Food Chem Toxicol 46:527-36. 2008
  6. ncbi Repeated administration of whole-cell and acellular pertussis vaccines affects haemodynamics and autonomic responsiveness
    J G Van Amsterdam
    Laboratory of Health Effects Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Vaccine 16:1668-74. 1998
  7. ncbi Significance of ammonium compounds on nicotine exposure to cigarette smokers
    E W Willems
    Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Food Chem Toxicol 44:678-88. 2006
  8. ncbi Determination of nicotine and cotinine in rat plasma by liquid chromatography-tandem mass spectrometry
    Alida Linda A M Stolker
    Laboratory for Organic Analytical Chemistry, National Institute for Public Health and the Environment RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    J Chromatogr A 1020:35-43. 2003
  9. ncbi Pertussis toxin-induced histamine sensitisation: an aspecific phenomenon independent from the nitric oxide system?
    Cornelia E van Meijeren
    National Institute for Public Health and the Environment, Laboratory of Toxicology, Pathology and Genetics, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Eur J Pharmacol 493:139-50. 2004
  10. ncbi Pertussis toxin relaxes small arteries with no vascular lesions or vascular smooth muscle cell injury
    Cornelia E van Meijeren
    Laboratory of Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    Exp Toxicol Pathol 56:139-43. 2004

Collaborators

  • H van Steeg
  • E W Willems
  • Alida A M Stolker
  • Reinskje Talhout
  • Cornelia E van Meijeren
  • Dick J de Wildt
  • Coenraad F M Hendriksen
  • Ton van de Kuil
  • F R Cassee
  • Jan van Amsterdam
  • J G Van Amsterdam
  • Antoon Opperhuizen
  • A Opperhuizen
  • A van de Kuil
  • C Y De Burbure
  • J G C van Amsterdam
  • P H B Fokkens
  • B Rambali
  • J A M A Dormans
  • T van de Kuil
  • J W van der Laan
  • D J de Wildt
  • J D te Biesebeek
  • Javotte Manni
  • Anne Loes Gerards
  • Jan A M A Dormans
  • Diane Kegler
  • J Wemer

Detail Information

Publications13

  1. ncbi ACE inhibitor-induced angioedema. Incidence, prevention and management
    W Vleeming
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Drug Saf 18:171-88. 1998
    ..Progress in pharmacogenetic and molecular biological research should throw more light on a possible genetic component in the pathogenesis of ACE inhibitor-associated angioedema...
  2. pmc Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats
    W Vleeming
    National Institute of Public Health en Environment, Laboratory of Health Effects Research, P O Box 1, NL 3720 BA Bilthoven, The Netherlands
    Br J Pharmacol 129:1801-7. 2000
    ..These results are considered to be a first step in the elucidation of the mechanism(s) of the HS test used in the quality control of acellular pertussis vaccine...
  3. ncbi The role of nitric oxide in cigarette smoking and nicotine addiction
    Wim Vleeming
    National Institute of Public Health and Environment, Laboratory of Health Effects Research, PO Box 1, NL 3720 BA Bilthoven, The Netherlands
    Nicotine Tob Res 4:341-8. 2002
    ..It also needs to be clarified whether NOS inhibitors or a low L-arginine diet might be useful in the treatment of nicotine addiction...
  4. ncbi The effect of pertussis toxin and whole-cell pertussis vaccine on haemodynamics and autonomic responsiveness in the rat depends on route of administration and age
    J G Van Amsterdam
    Laboratory of Health Effects Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Vaccine 16:666-71. 1998
    ..Present results show that adult rats are more sensitive to pertussis toxin and pertussis vaccine than young rats and that the responses depend on the route of administration...
  5. ncbi Subchronic inhalation of mixtures of cigarette smoke constituents in Xpa-/-p53+/- knock-out mice: a comparison of intermittent with semi-continuous exposure to acetaldehyde, formaldehyde, and acrolein
    F R Cassee
    Centre for Environmental Health Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Food Chem Toxicol 46:527-36. 2008
    ....
  6. ncbi Repeated administration of whole-cell and acellular pertussis vaccines affects haemodynamics and autonomic responsiveness
    J G Van Amsterdam
    Laboratory of Health Effects Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Vaccine 16:1668-74. 1998
    ..The observed effects on haemodynamics and autonomic control seem to be specific for pertussis toxin and pertussis-related vaccines as Haemophilus influenzae type b vaccine is in this respect virtually inactive...
  7. ncbi Significance of ammonium compounds on nicotine exposure to cigarette smokers
    E W Willems
    Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Food Chem Toxicol 44:678-88. 2006
    ..Scientific and public awareness of the effects of tobacco-specific ammonia compounds may stimulate global control, legislation and restriction of their use in cigarette manufacture...
  8. ncbi Determination of nicotine and cotinine in rat plasma by liquid chromatography-tandem mass spectrometry
    Alida Linda A M Stolker
    Laboratory for Organic Analytical Chemistry, National Institute for Public Health and the Environment RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    J Chromatogr A 1020:35-43. 2003
    ..The limit of identification of the developed method was 1 microg/l. The repeatability ranged from 5 to 12% (R.S.D.) for nicotine and from 3 to 5% for cotinine at the concentration level of 1-60 microg/l (n = 4)...
  9. ncbi Pertussis toxin-induced histamine sensitisation: an aspecific phenomenon independent from the nitric oxide system?
    Cornelia E van Meijeren
    National Institute for Public Health and the Environment, Laboratory of Toxicology, Pathology and Genetics, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Eur J Pharmacol 493:139-50. 2004
    ....
  10. ncbi Pertussis toxin relaxes small arteries with no vascular lesions or vascular smooth muscle cell injury
    Cornelia E van Meijeren
    Laboratory of Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    Exp Toxicol Pathol 56:139-43. 2004
    ..In conclusion, the PT-induced decreased contractile properties of isolated rat small resistance arteries are not caused by a PT-induced vascular and/or smooth muscle cell injury...
  11. ncbi Contribution of monoamine oxidase (MAO) inhibition to tobacco and alcohol addiction
    Jan van Amsterdam
    Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment RIVM, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Life Sci 79:1969-73. 2006
    ..It is concluded that the inhibition of MAO by constituents contained in tobacco and tobacco smoke, enhances the addiction induced by tobacco smoking...
  12. ncbi In vivo pertussis toxin treatment reduces contraction of rat resistance arteries but not that of mouse trachea
    Cornelia E van Meijeren
    National Institute for Public Health and Environment, Laboratory of Toxicology, Pathology and Genetics, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Eur J Pharmacol 488:127-35. 2004
    ....
  13. ncbi Letter to the editor
    Wim Vleeming
    Food Chem Toxicol 42:865-6; author reply 867. 2004