D van Soolingen

Summary

Affiliation: National Institute for Public Health and the Environment
Country: The Netherlands

Publications

  1. ncbi [Findings and ongoing research in the molecular epidemiology of tuberculosis]
    Dick van Soolingen
    National Institute for Public Health and the Environment, BA Bilthoven, The Netherlands
    Kekkaku 84:83-9. 2009
  2. pmc Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam
    Nguyen Thi Ngoc Lan
    Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam
    Emerg Infect Dis 9:1633-5. 2003
  3. pmc Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology
    Karine Brudey
    Unite de la Tuberculose et des Mycobacteries, Institut Pasteur de Guadeloupe, Guadeloupe
    BMC Microbiol 6:23. 2006
  4. pmc M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania
    Gibson S Kibiki
    Department of Internal Medicine, Endoscopy Unit, Kilimanjaro Christian Medical Centre, Tumaini University, Moshi, Tanzania
    BMC Microbiol 7:51. 2007
  5. pmc The use of microbead-based spoligotyping for Mycobacterium tuberculosis complex to evaluate the quality of the conventional method: providing guidelines for Quality Assurance when working on membranes
    Edgar Abadia
    Institute of Genetics and Microbiology UMR8621, CNRS Université Paris Sud 11 Universud, Campus d Orsay, F 91405 Orsay cedex, France
    BMC Infect Dis 11:110. 2011
  6. ncbi Mutations at amino acid position 315 of the katG gene are associated with high-level resistance to isoniazid, other drug resistance, and successful transmission of Mycobacterium tuberculosis in the Netherlands
    D van Soolingen
    Mycobacteria Reference Laboratory, RIVM LIS pb22, 3720 BA Bilthoven, The Netherlands
    J Infect Dis 182:1788-90. 2000
  7. ncbi Molecular epidemiology of tuberculosis in the Netherlands: a nationwide study from 1993 through 1997
    D van Soolingen
    Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Infect Dis 180:726-36. 1999
  8. pmc IS1245 restriction fragment length polymorphism typing of Mycobacterium avium isolates: proposal for standardization
    D van Soolingen
    Diagnostic Laboratory of Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Clin Microbiol 36:3051-4. 1998
  9. pmc Diagnosis of Mycobacterium microti infections among humans by using novel genetic markers
    D van Soolingen
    Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Clin Microbiol 36:1840-5. 1998
  10. ncbi Molecular epidemiology of tuberculosis and other mycobacterial infections: main methodologies and achievements
    D van Soolingen
    Mycobacteria Reference Department, Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Intern Med 249:1-26. 2001

Collaborators

Detail Information

Publications54

  1. ncbi [Findings and ongoing research in the molecular epidemiology of tuberculosis]
    Dick van Soolingen
    National Institute for Public Health and the Environment, BA Bilthoven, The Netherlands
    Kekkaku 84:83-9. 2009
    ..While in The Netherlands the organization of tuberculosis (TB) control in the era of elimination is being discussed, worldwide TB is still a major problem...
  2. pmc Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam
    Nguyen Thi Ngoc Lan
    Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam
    Emerg Infect Dis 9:1633-5. 2003
    ..8, 95% confidence interval 1.5 to 5.2)...
  3. pmc Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology
    Karine Brudey
    Unite de la Tuberculose et des Mycobacteries, Institut Pasteur de Guadeloupe, Guadeloupe
    BMC Microbiol 6:23. 2006
    ....
  4. pmc M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania
    Gibson S Kibiki
    Department of Internal Medicine, Endoscopy Unit, Kilimanjaro Christian Medical Centre, Tumaini University, Moshi, Tanzania
    BMC Microbiol 7:51. 2007
    ..TB positive culture, BAL fluid or sputum samples from 130 patients were collected and genotyped. The spoligotypes were correlated with anti-tuberculous drug susceptibility in HIV-infected and non-HIV patients from Tanzania...
  5. pmc The use of microbead-based spoligotyping for Mycobacterium tuberculosis complex to evaluate the quality of the conventional method: providing guidelines for Quality Assurance when working on membranes
    Edgar Abadia
    Institute of Genetics and Microbiology UMR8621, CNRS Université Paris Sud 11 Universud, Campus d Orsay, F 91405 Orsay cedex, France
    BMC Infect Dis 11:110. 2011
    ..Nine hundred and twenty-seven isolates were analyzed totaling 39,861 data points. Samples were received from 11 international laboratories with a worldwide distribution...
  6. ncbi Mutations at amino acid position 315 of the katG gene are associated with high-level resistance to isoniazid, other drug resistance, and successful transmission of Mycobacterium tuberculosis in the Netherlands
    D van Soolingen
    Mycobacteria Reference Laboratory, RIVM LIS pb22, 3720 BA Bilthoven, The Netherlands
    J Infect Dis 182:1788-90. 2000
    ..Thus, aa 315 mutants lead to secondary cases of tuberculosis as often as INH-susceptible strains do...
  7. ncbi Molecular epidemiology of tuberculosis in the Netherlands: a nationwide study from 1993 through 1997
    D van Soolingen
    Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Infect Dis 180:726-36. 1999
    ..Human immunodeficiency virus infection was not an independent risk factor for active transmission. Isoniazid-resistant strains were relatively less frequently clustered, suggesting that these generated fewer secondary cases...
  8. pmc IS1245 restriction fragment length polymorphism typing of Mycobacterium avium isolates: proposal for standardization
    D van Soolingen
    Diagnostic Laboratory of Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Clin Microbiol 36:3051-4. 1998
    ..Moreover, by combining international DNA typing results of M. avium complex isolates from a broad spectrum of sources, long-lasting questions on the epidemiology of this major agent of mycobacterial infections will be answered...
  9. pmc Diagnosis of Mycobacterium microti infections among humans by using novel genetic markers
    D van Soolingen
    Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Clin Microbiol 36:1840-5. 1998
    ..microti strains isolated in The Netherlands, suggesting that geographic isolation led to divergent strains in the United Kingdom and on the continent...
  10. ncbi Molecular epidemiology of tuberculosis and other mycobacterial infections: main methodologies and achievements
    D van Soolingen
    Mycobacteria Reference Department, Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Intern Med 249:1-26. 2001
    ..tuberculosis complex (atypical) mycobacteria. Important new insights that have been gained through molecular techniques into epidemiological aspects and diagnosis of mycobacterial diseases are highlighted...
  11. ncbi Analysis of rate of change of IS6110 RFLP patterns of Mycobacterium tuberculosis based on serial patient isolates
    A S de Boer
    National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Infect Dis 180:1238-44. 1999
    ..1-5.0). The main implication of this study is that the rate of change of IS6110-based RFLP of M. tuberculosis supports the use of IS6110 typing in epidemiologic studies of recent transmission of tuberculosis...
  12. ncbi The Beijing genotype is associated with young age and multidrug-resistant tuberculosis in rural Vietnam
    T N Buu
    Pham Ngoc Thach Tuberculosis and Lung Disease Hospital, Ho Chi Minh City, Vietnam
    Int J Tuberc Lung Dis 13:900-6. 2009
    ....
  13. pmc Genetic heterogeneity in Mycobacterium tuberculosis isolates reflected in IS6110 restriction fragment length polymorphism patterns as low-intensity bands
    A S de Boer
    Department of Infectious Disease Epidemiology, National Institute of Public Health and the Environment RIVM, 3720 BA Bilthoven, The Netherlands
    J Clin Microbiol 38:4478-84. 2000
    ..tuberculosis to changes in the environmental conditions during the dormant state or reactivation thereafter...
  14. pmc Comparison of methods based on different molecular epidemiological markers for typing of Mycobacterium tuberculosis complex strains: interlaboratory study of discriminatory power and reproducibility
    K Kremer
    Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, 3720 BA Bilthoven, The Netherlands
    J Clin Microbiol 37:2607-18. 1999
    ..tuberculosis strains. Several separate genotype families within the M. tuberculosis complex could be recognized on the basis of the genetic markers used...
  15. ncbi Exogenous re-infection as a cause of recurrent tuberculosis in a low-incidence area
    A S de Boer
    Centre for Infectious Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Int J Tuberc Lung Dis 7:145-52. 2003
    ..Surveillance data from the National Tuberculosis Register for the period 1993-1997 complemented with DNA fingerprinting results of Mycobacterium tuberculosis isolates...
  16. ncbi Drug resistance among failure and relapse cases of tuberculosis: is the standard re-treatment regimen adequate?
    H T W Quy
    Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam
    Int J Tuberc Lung Dis 7:631-6. 2003
    ..To determine acquired drug resistance among failure and relapse cases after treatment of new smear-positive tuberculosis...
  17. pmc Correlation of virulence, lung pathology, bacterial load and delayed type hypersensitivity responses after infection with different Mycobacterium tuberculosis genotypes in a BALB/c mouse model
    J Dormans
    Laboratory for Toxicology, Pathology and Genetics, National Institute of Public Health and Environment RIVM, Bilthoven, The Netherlands
    Clin Exp Immunol 137:460-8. 2004
    ..A severe pathological response correlates with a high mortality and a high CFU counts in lungs, but poorly with the degree of the DTH response...
  18. ncbi Environmental sources of rapid growing nontuberculous mycobacteria causing disease in humans
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Clin Microbiol Infect 15:888-93. 2009
    ..Furthermore, studies should focus on the actual sites of the active replication of RGM; their presence may not indicate their natural habitat...
  19. doi Proposal to elevate Mycobacterium avium complex ITS sequevar MAC-Q to Mycobacterium vulneris sp. nov
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Int J Syst Evol Microbiol 59:2277-82. 2009
    ..avium complex strains sharing this 16S gene and MAC-Q ITS sequence to separate species status, for which the name Mycobacterium vulneris sp. nov. is proposed. The type strain is NLA000700772T (=DSM 45247T=CIP 109859T)...
  20. doi Clinical relevance of Mycobacterium simiae in pulmonary samples
    J van Ingen
    Dept of Pulmonary Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Eur Respir J 31:106-9. 2008
    ..simiae infection. Further studies are required in order to improve diagnostic criteria and treatment regimens...
  21. pmc Clinical Mycobacterium conspicuum isolation from two immunocompetent patients in The Netherlands
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Clin Microbiol 45:4075-6. 2007
  22. ncbi Second-line drug resistance in multidrug-resistant tuberculosis cases of various origins in the Netherlands
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Tuberc Lung Dis 12:1295-9. 2008
    ..The Netherlands...
  23. doi Clinical relevance of non-tuberculous mycobacteria isolated in the Nijmegen-Arnhem region, The Netherlands
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Thorax 64:502-6. 2009
    ..The frequency of clinical isolation of non-tuberculous mycobacteria (NTM) in the Netherlands is increasing, but its clinical relevance is often uncertain...
  24. ncbi The changing pattern of clinical Mycobacterium avium isolation in the Netherlands
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Tuberc Lung Dis 14:1176-80. 2010
    ..National Mycobacteria Reference Laboratory, The Netherlands...
  25. doi Re-analysis of 178 previously unidentifiable Mycobacterium isolates in the Netherlands in 1999-2007
    J van Ingen
    Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Microbiol Infect 16:1470-4. 2010
    ..The number of NTM species in the environment is probably so high that unidentifiable clinical isolates should be given a separate species status only if this is clinically meaningful...
  26. ncbi [Nontuberculous mycobacteria: clinically relevant]
    Jakko van Ingen
    Radboud Universiteit Nijmegen Medisch Centrum, afd Longziekten, Nijmegen, en Universitair Centrum voor Chronische Ziekten Dekkerswald, Groesbeek, The Netherlands
    Ned Tijdschr Geneeskd 154:A1178. 2010
    ..Therefore, prompt consultation with one of the specialized centres of expertise is warranted. We should also consider formulating national guidelines for diagnosis and treatment...
  27. doi Tuberculosis seasonality in the Netherlands differs between natives and non-natives: a role for vitamin D deficiency?
    H Korthals Altes
    Epidemiology and Surveillance, Tuberculosis and M XDR TB Programme, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Int J Tuberc Lung Dis 16:639-44. 2012
    ..The seasonality of tuberculosis (TB) incidence suggests that the risk of infection or development of disease has a seasonal component...
  28. ncbi Pathological and immunological effects of respirable coal fly ash in male Wistar rats
    J A Dormans
    Laboratory for Pathology and Immunobiology, National Institute of Public Health and the Environment, P O Box 1, 3720 BA Bilthoven, The Netherlands
    Inhal Toxicol 11:51-69. 1999
    ..Whether these observed alterations may effect the host resistance must be learned from infection studies...
  29. pmc Rapid identification of mycobacteria by Raman spectroscopy
    P C A M Buijtels
    University Medical Centre Utrecht, Department of Medical Microbiology, HP G04 614, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    J Clin Microbiol 46:961-5. 2008
    ..Raman spectroscopy provides a novel answer to the need for rapid species identification of cultured mycobacteria in a clinical diagnostic setting...
  30. ncbi Tuberculosis contact investigation and DNA fingerprint surveillance in The Netherlands: 6 years' experience with nation-wide cluster feedback and cluster monitoring
    C S B Lambregts-van Weezenbeek
    Royal Netherlands Tuberculosis Association KNCV, The Hague, The Netherlands
    Int J Tuberc Lung Dis 7:S463-70. 2003
    ..The Netherlands, 1995-2000...
  31. ncbi Molecular epidemiology of Mycobacterium tuberculosis in China: a nationwide random survey in 2000
    W M Li
    Department of Bacteriology and Immunology, Beijing Tuberculosis and Thoracic Tumour Research Institute, Beijing People s Republic of China
    Int J Tuberc Lung Dis 9:1314-9. 2005
    ..To determine the contribution of the Mycobacterium tuberculosis (TB) Beijing genotype to the population structure of M. tuberculosis complex in China...
  32. pmc The effect of age and study duration on the relationship between 'clustering' of DNA fingerprint patterns and the proportion of tuberculosis disease attributable to recent transmission
    E Vynnycky
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine
    Epidemiol Infect 126:43-62. 2001
    ....
  33. pmc Lymphadenitis in children is caused by Mycobacterium avium hominissuis and not related to 'bird tuberculosis'
    L E S Bruijnesteijn van Coppenraet
    Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Clin Microbiol Infect Dis 27:293-9. 2008
    ..avium isolates, and all belonged to the M. avium hominissuis subspecies. A relation to pet birds in the etiology of mycobacterial lymphadenitis could not be established, and the source of the infections may be environmental...
  34. ncbi Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae
    B Wieles
    Department of Immunohaematology and Blood Bank, Leiden University Hospital, The Netherlands
    Mol Microbiol 16:921-9. 1995
    ..leprae. These findings demonstrate the very unusual phenomenon of a single gene coding for both the substrate (thioredoxin) and the enzyme (thioredoxin reductase), which seems to be unique to M. leprae...
  35. ncbi Efficient differentiation of Mycobacterium tuberculosis strains of the W-Beijing family from Russia using highly polymorphic VNTR loci
    O V Surikova
    Pharmacogenomics Group, Institute of Chemical Biology and Fundamental Medicine, SB RAS, Novosibirsk, Russia
    Eur J Epidemiol 20:963-74. 2005
    ..VNTR typing in proposed format is powerful tool for discrimination of M. tuberculosis strains with different level of genetic relationship...
  36. ncbi First description of Mycobacterium tuberculosis Beijing genotype in Argentina
    N Morcillo
    Laboratorio de Referencia del Programa de Control de Tuberculosis de la Provincia de Buenos Aires, V López
    Rev Argent Microbiol 37:92-5. 2005
    ..These findings might be partially explained by the important migration phenomena occurred during the last decade. Further surveillance studies would help in the following of Beijing family strain dissemination in our community...
  37. ncbi The impact of nontuberculous mycobacteria on management of presumed pulmonary tuberculosis
    R van Crevel
    Dept of Internal Medicine, University Medical Center Nijmegen, The Netherlands
    Infection 29:59-63. 2001
    ..Reliable DNA-based techniques and better communication between physicians and microbiologists may improve management of suspected mycobacterial infections...
  38. pmc Seventy percent of the Mycobacterium tuberculosis isolates in Hong Kong represent the Beijing genotype
    M Y Chan
    Tuberculosis Reference Laboratory, Department of Health, Hong Kong, Kwun Tong, Kowloon
    Epidemiol Infect 127:169-71. 2001
    ..This is the first geographical area where genetic diversity among 'Beijing' genotype of MTB strains has been observed on this scale...
  39. pmc Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research
    J A Langermans
    Departments of Parasitology and Animal Science, Biomedical Primate Research Centre, P.O. Box 3306, 2280 GH Rijswijk, The Netherlands
    Proc Natl Acad Sci U S A 98:11497-502. 2001
    ..Comparative studies in these closely related species are likely to provide insight into mechanisms involved in protection against tuberculosis...
  40. pmc A new evolutionary scenario for the Mycobacterium tuberculosis complex
    R Brosch
    Unite de Genetique Moleculaire Bacterienne, Laboratoire de Génomique des Microorganismes Pathogènes, and Centre National de Référence des Mycobactéries, Institut Pasteur, 25 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 99:3684-9. 2002
    ..bovis lineage separated from the M. tuberculosis lineage. This observation suggests that the common ancestor of the tubercle bacilli resembled M. tuberculosis or M. canettii and could well have been a human pathogen already...
  41. ncbi Effect of screening of immigrants on tuberculosis transmission
    S Verver
    Royal Netherlands Tuberculosis Association KNCV, The Hague
    Int J Tuberc Lung Dis 6:121-9. 2002
    ..In The Netherlands all immigrants from highly endemic countries undergo obligatory entry screening by X-ray, followed by voluntary half-yearly screening for 2 years...
  42. ncbi Predominace of a novel Mycobacterium tuberculosis genotype in the Delhi region of India
    N Vijaya Bhanu
    Department of Microbiology, All India Institute of Medical Sciences, New Delhi 110 029, India
    Tuberculosis (Edinb) 82:105-12. 2002
    ..Future studies may disclose the genetic characteristics of strains belonging to the Delhi genotype, analogous to the recently observed virulence among the Beijing genogroup...
  43. pmc Improvement of differentiation and interpretability of spoligotyping for Mycobacterium tuberculosis complex isolates by introduction of new spacer oligonucleotides
    A G M Van Der Zanden
    Medical Microbiology and Infectious Diseases, Gelre Hospitals, Location Lukas, Apeldoorn, The Netherlands
    J Clin Microbiol 40:4628-39. 2002
    ..g., for low-copy-number IS6110 strains or for phylogenetic studies of Beijing genotype strains...
  44. ncbi A low cost, home-made, reverse-line blot hybridisation assay for rapid detection of rifampicin resistance in Mycobacterium tuberculosis
    N Morcillo
    Mycobacterial Regional Reference Laboratory, Tuberculosis Control Programme of Buenos Aires Province, Argentina
    Int J Tuberc Lung Dis 6:959-65. 2002
    ..Cetrangolo Hospital, Vicente Lopez, Argentina, 1995-1999...
  45. pmc Use of DNA extracts from Ziehl-Neelsen-stained slides for molecular detection of rifampin resistance and spoligotyping of Mycobacterium tuberculosis
    A G M Van Der Zanden
    Medical Microbiology and Infectious Diseases, Gelre Hospitals, Location Lukas, Apeldoorn, The Netherlands
    J Clin Microbiol 41:1101-8. 2003
    ..The nature of rifampin resistance and the genotype can be determined by analysis of Ziehl-Neelsen-stained slides in a laboratory equipped for sequencing and spoligotyping without the need to ship biohazardous materials...
  46. pmc A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes
    B Lopez
    National Institute for Infectious Diseases, National Administration of Health Laboratories and Institutes Carlos G Malbrán, Buenos Aires, Argentina
    Clin Exp Immunol 133:30-7. 2003
    ..Future immunological research, particularly on candidate vaccines, should include a broad spectrum of M. tuberculosis genotypes rather than a few laboratory strains...
  47. ncbi [Research into new methods for diagnosing, treating and preventing tuberculosis]
    M W Borgdorff
    Academisch Medisch Centrum Universiteit van Amsterdam, Amsterdam
    Ned Tijdschr Geneeskd 147:1838-41. 2003
    ..However, new candidate vaccines are being developed and will be tested on humans in the near future...
  48. pmc Molecular characteristics and global spread of Mycobacterium tuberculosis with a western cape F11 genotype
    Thomas C Victor
    MRC Centre for Molecular and Cellular Biology, Department of Medical Biochemistry, University of Stellenbosch, Tygerberg 7505, South Africa
    J Clin Microbiol 42:769-72. 2004
    ..Careful study of dominant compared to rare strains should provide clues to their success and possibly provide new ideas for combating TB...
  49. ncbi Analysis of genetic polymorphisms affecting the four phospholipase C (plc) genes in Mycobacterium tuberculosis complex clinical isolates
    C Viana-Niero
    Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Sao Paulo Escola Paulista de Medicina UNIFESP EPM, Rua Botucatu, 862 3rd andar, 04023 062, Sao Paulo, Brazil
    Microbiology 150:967-78. 2004
    ....
  50. ncbi Pneumonia caused by Mycobacterium kansasii in a series of patients without recognised immune defect
    S M Arend
    Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Clin Microbiol Infect 10:738-48. 2004
    ..kansasii infections. The identical fingerprint patterns of the isolates suggested the existence of a virulent strain of M. kansasii...
  51. pmc Systematic molecular characterization of multidrug-resistant Mycobacterium tuberculosis complex isolates from Spain
    S Samper
    Servicio de Microbiologia, Hospital Universitario Miguel Servet, C Isabel la Católica 1 3, 50009 Zaragoza, Spain
    J Clin Microbiol 43:1220-7. 2005
    ..The 22 isolates in the largest cluster corresponded to the Mycobacterium bovis strain responsible for two nosocomial MDR outbreaks in Spain...
  52. pmc Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis genotypes
    R Chacón-Salinas
    Department of Immunology, National School of Biological Sciences, ENCB IPN, Mexico
    Clin Exp Immunol 140:443-9. 2005
    ..Results presented in this work show that each genotype has the ability to induce different levels of cytokine expression that could be related to its pathogenesis during infection...
  53. ncbi [An outbreak of multiresistant tuberculosis from Eastern Europe in the Netherlands]
    G de Vries
    Gemeentelijke Gezondheidsdienst Rotterdam e o, afd Tuberculose bestrijding, Postbus 70 032, 3000 LP Rotterdam
    Ned Tijdschr Geneeskd 149:1921-4. 2005
    ..This is the first time an outbreak of multiresistant tuberculosis of this magnitude is described in the Netherlands...
  54. pmc Mycobacterium tuberculosis Beijing genotype emerging in Vietnam
    D D Anh
    National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
    Emerg Infect Dis 6:302-5. 2000
    ..Three hundred one (54%) patients were infected with Beijing genotype strains. The genotype was associated with younger age (and hence with active transmission) and with isoniazid and streptomycin resistance, but not with BCG vaccination...