Research Topics
Genomes and GenesSpecies | J C SeidellSummaryAffiliation: National Institute for Public Health and the Environment Country: The Netherlands Publications
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Publications
Body weight and weight change and their health implications for the elderlyJ C Seidell
Department of Chronic Diseases Epidemiology, National Institute of Public Health, Bilthoven, The Netherlands
Eur J Clin Nutr 54:S33-9. 2000..Low lean body mass is probably better reflected by low BMI, whereas increased (abdominal) fatness is better reflected by increased waist circumference...
The impact of obesity on health status: some implications for health care costsJ C Seidell
Department of Chronic Disease and Environmental Epidemiology, National Institute of Public Health and Environmental Protection RIVM, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 19:S13-6. 1995..This ranks obesity among the major determinants of health care costs...
Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family StudyJ C Seidell
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, Netherlands
Am J Clin Nutr 74:315-21. 2001..A high waist-to-hip ratio is associated with unfavorable cardiovascular disease risk factors. This could be due to either a relatively large waist or a small hip girth...
Narrow hips and broad waist circumferences independently contribute to increased risk of non-insulin-dependent diabetes mellitusJ C Seidell
Department for Chronic Diseases and Environmental Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
J Intern Med 242:401-6. 1997..In this study, we tried to dissociate obesity, waist and hip circumference from NIDDM...
Dietary fat and obesity: an epidemiologic perspectiveJ C Seidell
Department of Chronic Diseases and Environmental Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Am J Clin Nutr 67:546S-550S. 1998..At this stage there is no conclusive evidence from epidemiologic studies that under isoenergetic conditions dietary fat intake promotes the development of obesity more so than other macronutrients...
Obesity, insulin resistance and diabetes--a worldwide epidemicJ C Seidell
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Br J Nutr 83:S5-8. 2000..Such strategies are not developed or implemented. These developments point toward the great urgency to develop global and national plans for adequate prevention and management of obesity and type 2 diabetes mellitus...
Societal and personal costs of obesityJ C Seidell
Department of Chronic Diseases and Environmental Epidemiology, National Institute of Public Health and Environmental Protection RIVM, The Netherlands
Exp Clin Endocrinol Diabetes 106:7-9. 1998..An appropriate analysis of all costs associated with obesity is important in order to persuade responsible bodies to develop strategies towards the prevention and long-term management of obesity...
Overweight and obesity in the mortality rate data: current evidence and research issuesJ C Seidell
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Med Sci Sports Exerc 31:S597-601. 1999..The relation between indicators of overweight (body mass index (BMI)) and all-cause mortality and factors that potentially affect such a relationship were reviewed...
Parental history of diabetes modifies the association between abdominal adiposity and hyperglycemiaR M van Dam
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Diabetes Care 24:1454-9. 2001..To examine whether the association between abdominal obesity and hyperglycemia differs according to the presence of a parental history of diabetes...
Physical activity modulates the effect of a lipoprotein lipase mutation (D9N) on plasma lipids and lipoproteinsJ M Boer
Department of Chronic Disease Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Clin Genet 56:158-63. 1999..In conclusion, a common variant of the LPL gene (D9N) adversely affects plasma lipid and lipoprotein profiles. However, the unfavorable consequences may be counteracted by physical activity...
Lipid profiles reflecting high and low risk for coronary heart disease: contribution of apolipoprotein E polymorphism and lifestyleJ M Boer
Department of Chronic Disease and Environmental Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Atherosclerosis 136:395-402. 1998..Our results suggest that both modifiable factors and the apolipoprotein E polymorphism contribute to a lipid profile, reflecting low, average and high risk for coronary heart disease, but effects may be gender-specific...
The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studiesR M van Dam
Center of Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Diabet Med 21:752-8. 2004..The aim of this study was to test the hypothesis that the IRS-1 Gly972Arg variant increases risk of Type 2 diabetes...
Physical activity and dietary fiber determine population body fat levels: the Seven Countries StudyD Kromhout
Division of Public Health Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 25:301-6. 2001..A global epidemic of obesity is developing. Current prevalence rates are about 20-25% in American adults and 15-20% in Europeans...
The public health impact of obesityT L Visscher
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, The Netherlands
Annu Rev Public Health 22:355-75. 2001..Obesity prevention programs should be high on the scientific and political agenda in both industrialized and industrializing countries...
Parental history of myocardial infarction: lipid traits, gene polymorphisms and lifestyleJ M Boer
Department of Chronic Disease Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Atherosclerosis 155:149-56. 2001..Therefore, other genetic or lifestyle-related factors must be responsible for the increased levels of apo B in individuals with a family history of myocardial infarction...
Time trends (1993-1997) and seasonal variation in body mass index and waist circumference in the NetherlandsT L S Visscher
Centre for Prevention and Health Services Research, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 28:1309-16. 2004..To compare the time trend and seasonal variation in body mass index (BMI) and waist circumference...
Polymorphisms in the NPY and AGRP genes and body fatness in Dutch adultsC T M van Rossum
Centre for Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes (Lond) 30:1522-8. 2006..To investigate the association between DNA polymorphisms in the NPY and AGRP genes and body fatness...
Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population-based studies and meta-analysesR M van Dam
Centre of Nutrition and Health, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Diabet Med 22:590-8. 2005..To evaluate the relation between common variants in the ATP-sensitive K+ channel genes and glucose intolerance...
Prevalence and time trends of obesity in EuropeJ C Seidell
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment (RIVM, BA Bilthoven, The Netherlands
J Endocrinol Invest 25:816-22. 2002
Long-term and recent time trends in the prevalence of obesity among Dutch men and womenT L S Visscher
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 26:1218-24. 2002..To describe long-term and recent time trends in the prevalence of obesity by age and educational level...
Time trends in obesity: an epidemiological perspectiveJ C Seidell
Department for Chronic Diseases and Environmental Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Horm Metab Res 29:155-8. 1997..The rising prevalence of non-insulin dependent diabetes mellitus may be one of the first signs of the increasing problem of obesity in European countries...
The relationship between quality of life and perceived body weight and dieting history in Dutch men and womenC M Burns
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 25:1386-92. 2001..1) To study the relationship between quality of life (QoL) and measured and perceived weight and dieting history in Dutch men and women; (2) to assess the effect of weight loss over a 5 y period on QoL...
[Physical activity in relation to sociodemographic variables and health status of adult men and women in Amsterdam, Doetinchen and Maastricht]A J Schuit
Rijksinstituut voor Volksgezondheid en Milieu, Centrum voor Chronische Ziekten Epidemiologie, Bilthoven
Ned Tijdschr Geneeskd 143:1559-64. 1999....
A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: the Rotterdam studyT L Visscher
Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
Int J Obes Relat Metab Disord 25:1730-5. 2001..To compare body mass index (BMI), waist-hip ratio (WHR) and waist circumference as predictors of all-cause mortality among the elderly...
Genetic factors as predictors of weight gain in young adult Dutch men and womenC T M van Rossum
Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Int J Obes Relat Metab Disord 26:517-28. 2002..Polymorphisms in these genes may contribute to weight gain through effects on energy intake, energy expenditure or adipogenesis...
The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometryM B Snijder
Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
Int J Obes Relat Metab Disord 26:984-93. 2002..The aim of the present study is to investigate whether the dual-energy X-ray absorptiometry (DXA) method, possibly combined with anthropometry, offers a good alternative to CT for the prediction of visceral fat in the elderly...
Prevalence of overweight and obesity in the NetherlandsD F Schokker
Institute of Health Sciences, VU University, Amsterdam, The Netherlands
Obes Rev 8:101-8. 2007....
Diet, nutrition and the prevention of excess weight gain and obesityB A Swinburn
Physical Activity and Nutrition Research Unit, School of Health Sciences, Deakin University, Melbourne, Australia
Public Health Nutr 7:123-46. 2004..To review the evidence on the diet and nutrition causes of obesity and to recommend strategies to reduce obesity prevalence...
Netherlands research programme weight gain prevention (NHF-NRG): rationale, objectives and strategiesS P J Kremers
Department of Health Education and Promotion, Maastricht University, The Netherlands
Eur J Clin Nutr 59:498-507. 2005....
Leptin and insulin responses to a four-day energy-deficient diet in men with different weight historyM Mars
Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, The Netherlands
Int J Obes Relat Metab Disord 27:574-81. 2003..To assess the leptin responses to a 4-day energy-restricted diet in men with different weight history; high retrospective weight gain was expected to be associated with a small decline in leptin...
[Nutrition and health--obesity]J C Seidell
Vrije Universiteit, Faculteit Aard en Levenswetenschappen, afd Voeding en Gezondheid, De Boelelaan 1085, 1081 HV Amsterdam
Ned Tijdschr Geneeskd 147:281-6. 2003..Physical activity is an essential component of a weight loss strategy. Moderate sustained weight loss is associated with a strong reduction in the risk of type 2 diabetes mellitus in people with impaired glucose tolerance...
Carbohydrate intake and obesityR M van Dam
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Eur J Clin Nutr 61:S75-99. 2007..Although it is difficult to establish with certainty that fiber rather than other dietary attributes are responsible, whole-grain cereals, vegetables, legumes and fruits seem to be the most appropriate sources of dietary carbohydrate...
Overweight, obesity and fat distribution in 50- to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)M Haftenberger
Department of Epidemiology, German Institute of Human Nutrition, Arthur Scheunert Allee 114 116, D 14558 Potsdam Rehbrücke, Germany
Public Health Nutr 5:1147-62. 2002..To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC)...
The prevention of overweight and obesity in children and adolescents: a review of interventions and programmesC M Doak
Institute of Health Sciences, Vrije Universiteit, Amsterdam, The Netherlands
Obes Rev 7:111-36. 2006..Because few studies report on underweight prevalence, this review recommends giving more attention to preventing adverse outcomes by reporting the intervention impact on the frequency distribution for both BMI and adiposity measures...
Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The Health ABC StudyM B Snijder
Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
Diabetologia 48:301-8. 2005..Our secondary aim was to investigate which body composition characteristics (lean tissue, fat tissue) are reflected by anthropometric measures (waist and thigh circumference)...
Comment on: Schmidt MI, Duncan BB, Vigo A et al (2006) Leptin and incident type 2 diabetes: risk or protection? Diabetologia 49:2086-2096M B Snijder
Diabetologia 50:234-6; author reply 237-8; discussion 239-40. 2007
Vitamin D status and parathyroid hormone levels in relation to blood pressure: a population-based study in older men and womenM B Snijder
Institute of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
J Intern Med 261:558-65. 2007..Effects of poor vitamin D status on blood pressure may be mediated by elevated parathyroid hormone (PTH) levels...
Does the relationship between waist circumference, morbidity and mortality depend on measurement protocol for waist circumference?R Ross
School of Kinesiology and Health Studies, Queen s University, Kingston, ON, Canada
Obes Rev 9:312-25. 2008..Our findings suggest that WC measurement protocol has no substantial influence on the association between WC, all-cause and CVD mortality, CVD and diabetes...
The association between antihypertensive drug therapies and plasma lipid levels in the general populationA H Maitland-van der Zee
Utrecht Institute for Pharmaceutical Sciences (UIPS, Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht University, Utrecht, The Netherlands
J Hum Hypertens 15:701-5. 2001..The combination of a diuretic and a beta-blocker was associated with a worse lipid profile...
What aspects of body fat are particularly hazardous and how do we measure them?M B Snijder
Institute of Health Sciences, Faculty of Earth and Life Sciences, Vrije Universiteit Amsterdam, The Netherlands
Int J Epidemiol 35:83-92. 2006
Development and validation of a hospital screening tool for malnutrition: the short nutritional assessment questionnaire (SNAQ)H M Kruizenga
Department of Dietetics, VU University Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
Clin Nutr 24:75-82. 2005..The validity, the nurse-nurse reproducibility and nurse-dietitian reproducibility was tested in another but similar population of 297 patients...
[The value and limitations of the body mass index (BMI) in the assessment of the health risks of overweight and obesity]P Kok
Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Postbus 9600, 2300 RC, Leiden
Ned Tijdschr Geneeskd 148:2379-82. 2004..The BMI does not give any insight into regional body fat distribution. Waist circumference is a valid index of visceral fat accumulation and can therefore be used as an indicator of health risks associated with visceral obesity...
[Overweight and obesity in children and adolescents and preventative measures]C M Renders
Vrije Universiteit Medisch Centrum, afd Sociale Geneeskunde, Instituut voor Extramuraal Geneeskundig Onderzoek, Van der Boechorststraat 7, 1081 BT Amsterdam
Ned Tijdschr Geneeskd 148:2066-70. 2004..With such preventive measures the involvement of both the school and the parents is important...
Influence of correction for within-person variability in blood pressure on the prevalence, awareness, treatment, and control of hypertensionO H Klungel
Department of Pharmacoepidemiology and Pharmacotherapy, Faculty of Pharmacy, Utrecht University, The Netherlands
Am J Hypertens 13:88-91. 2000..It may be advisable to perform a correction for within-person variability to obtain valid prevalence estimates in surveys that only take one or two measurements of blood pressure...
A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosisP W Reymer
Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Nat Genet 10:28-34. 1995..Our data support the relationship between LPL activity and HDL-C levels, and suggest that a specific LPL mutation may be a factor in the development of atherosclerosis...
Independent and opposite associations of waist and hip circumferences with diabetes, hypertension and dyslipidemia: the AusDiab StudyM B Snijder
International Diabetes Institute, Caulfield, Victoria, Australia
Int J Obes Relat Metab Disord 28:402-9. 2004..In addition, as previous studies were performed in older persons, we investigated whether these associations were present across adult age groups...
Is drug treatment of hypertension in clinical practice as effective as in randomized controlled trials with regard to the reduction of the incidence of stroke?O H Klungel
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, P O BOX 80082, 3508 TB Utrecht, The Netherlands
Epidemiology 12:339-44. 2001..The relative risk reduction that we found was similar to those found in randomized controlled trials...
[Overweight and mortality risk: no connection between overweight in middle and older age groups and increased mortality]J C Seidell
Ned Tijdschr Geneeskd 152:406; author reply 406-7. 2008
