Affiliation: National Institute for Public Health and the Environment
Country: The Netherlands
- Hospital networks and the dispersal of hospital-acquired pathogens by patient transferTjibbe Donker
Department of Medical Microbiology, University Medical Centre Groningen, Groningen, The Netherlands
PLoS ONE 7:e35002. 2012..Our findings stress the importance of cooperative effects that will have a bearing on the planning of health care systems, patient management and hospital infection control...
- Antimicrobial drug use and resistance in EuropeNienke van de Sande-Bruinsma
National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Emerg Infect Dis 14:1722-30. 2008..Ecologic studies based on routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial drug consumption at a national level in Europe...
- Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks modelsMartin Wolkewitz
Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany
Crit Care 12:R44. 2008..However, the evaluation in most of theses studies disregards the fact that there are additional competing events, such as discharge or death...
- Spatial effects of mosquito bednets on child mortalityLaura Gosoniu
Swiss Tropical Institute, Basel, Switzerland
BMC Public Health 8:356. 2008..We analyzed for the first time data from a large follow-up study in an area of high perennial malaria transmission in southern Tanzania to describe the spatial effects of bednets on all-cause child mortality...
- Polymorphism, genetic exchange and intragenic recombination of the aureolysin gene among Staphylococcus aureus strainsArtur J Sabat
National Medicines Institute, 00 725 Warsaw, Poland
BMC Microbiol 8:129. 2008..aureus population. Therefore, an epidemiologically and genetically diverse collection of S. aureus strains was used to determine the range of aureolysin (aur) gene polymorphism...
- PFGE diversity within the methicillin-resistant Staphylococcus aureus clonal lineage ST398Thijs Bosch
Centre for Infectious Disease Control, National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
BMC Microbiol 10:40. 2010..Therefore, a new PFGE using Cfr9I, a neoschizomer of SmaI was optimized and evaluated to investigate ST398 isolates...
- Cost-sharing strategies combining targeted public subsidies with private-sector delivery achieve high bednet coverage and reduced malaria transmission in Kilombero Valley, southern TanzaniaG F Killeen
Ifakara Health Research and Development Centre, Box 53, Ifakara, Morogoro, United Republic of Tanzania
BMC Infect Dis 7:121. 2007..Here we evaluate resulting changes in bednet coverage and malaria transmission...
- Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysisHajo Grundmann
National Institute for Public Health and the Environment, Bilthoven, The Netherlands
PLoS Med 7:e1000215. 2010..We aimed to map the geographic distribution of the dominant clones that cause invasive infections in Europe...
- A framework for global surveillance of antibiotic resistanceHajo Grundmann
University Medical Centre Groningen, Rijksuniversiteit Groningen, The Netherlands
Drug Resist Updat 14:79-87. 2011..e. priority setting for new drug development, comparative quantification of antibiotic effectiveness at local, national, regional and global level and identification of the action gaps can be helpful...
- Report of working group 1: public health challengesH Grundmann
European Antimicrobial Resistance Surveillance System, RijksInstituut voor Volksgezondheid and Milieu RIVM, Bilthoven, The Netherlands
Clin Microbiol Infect 11:36-40. 2005..The ESCMID should strengthen its role in harmonising and supporting the highest standards of training in the infection disciplines...
- Mathematical modelling: a tool for hospital infection controlH Grundmann
National Institute of Public Health and the Environment, Bilthoven, The Netherlands
Lancet Infect Dis 6:39-45. 2006..We also appraise their usefulness and limitations as an innovative research and decision tool for control purposes...
- The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance SystemM E A de Kraker
Centre for Infectious Disease Control, RIVM, Bilthoven, The Netherlands
Clin Microbiol Infect 19:860-8. 2013..It appears that infections with resistant clones add to rather than replace infections caused by susceptible bacteria. As a consequence, expansion of antibiotic resistance creates an additional strain on healthcare systems...
- Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strainsM A Leverstein-Van Hall
Department of Medical Microbiology, University Medical Centre Utrecht, The Netherlands
Clin Microbiol Infect 17:873-80. 2011..coli genotypes also present in human samples. These findings are suggestive for transmission of ESBL genes, plasmids and E. coli isolates from poultry to humans, most likely through the food chain...
- Dispersal of antibiotic-resistant high-risk clones by hospital networks: changing the patient direction can make all the differenceT Donker
Department of Medical Microbiology, University Medical Centre Groningen, University of Groningen, The Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Electronic address
J Hosp Infect 86:34-41. 2014..In this manner, different healthcare institutions become linked epidemiologically. All links combined form the national patient referral network, through which high-risk clones can propagate...
- Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporinsM E A de Kraker
Centre for Infectious Disease Control, National Institute for Public Health and the Environment, RIVM, Bilthoven, The Netherlands
J Antimicrob Chemother 66:398-407. 2011..This study determined excess mortality and length of hospital stay (LOS) attributable to bloodstream infection (BSI) caused by third-generation-cephalosporin-resistant Escherichia coli in Europe...
- Overview of molecular typing methods for outbreak detection and epidemiological surveillanceA J Sabat
Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Euro Surveill 18:20380. 2013....
- European-wide distribution of Pseudomonas aeruginosa clone CS D Dinesh
Research Group Clonal Variability, Division of Cell and Immune Biology, GBF German Research Center for Biotechnology, Braunschweig, Germany
Clin Microbiol Infect 9:1228-33. 2003..Therefore, P. aeruginosa clone C is widely distributed in Europe, with a broad pathogenic potential...
- Hospital infection control in Europe: evaluation of present practice and future goalsF D Daschner
Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Freiburg, Germany
Clin Microbiol Infect 10:263-6. 2004..The results of this survey might help to create a basis for standardised guidelines which take into account European-wide interests...
- [Incidence of transmission of pathogens in intensive care units. Results of the SIR 3 study]S Bärwolff
Institut fur Hygiene und Umweltmedizin, Charite, Universitatsmedizin, Berlin
Anaesthesist 54:560-6. 2005..5% of all nosocomial infections. The data of this study demonstrate that even in ICUs with average nosocomial infection rates, some nosocomial infections could be avoided...
- Correlation between the genetic diversity of nosocomial pathogens and their survival time in intensive care unitsP Gastmeier
Hannover Medical School, Institute of Medical Microbiology and Hospital Epidemiology, Hannover, Germany
J Hosp Infect 62:181-6. 2006..821, P=0.024). Environmental survival may be an important factor contributing to the ecological fitness of some nosocomial pathogens in ICUs. Infection control measures should consider this finding...
- Replacement of methicillin-resistant Staphylococcus aureus clones in Hungary over time: a 10-year surveillance studyT Conceição
Laboratorio de Genetica Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
Clin Microbiol Infect 13:971-9. 2007..85% of the 2001-2004 isolates. Thus, this study describes, for the first time, the co-dominance and extensive spread of the New York/Japan clone in a European country...
- Cross-transmission of nosocomial pathogens in an adult intensive care unit: incidence and risk factorsM Halwani
Division of Microbiology and Infectious Diseases, Medical School, Queen s Medical Centre, University of Nottingham, UK
J Hosp Infect 63:39-46. 2006..This study showed that cross-transmission of nosocomial pathogens in the ICU is associated with understaffing, immunosuppression and factors that result in multiple staff/patient contacts, thus emphasizing the importance of hand hygiene...
- Use of multistate models to assess prolongation of intensive care unit stay due to nosocomial infectionJ Beyersmann
Institute of Medical Biometry and Medical Informatics, University Hospital Freiburg, and Freiburg Centre for Data Analysis and Modeling, University of Freiburg, Eckerstrasse 1, D 79104 Freiburg, Germany
Infect Control Hosp Epidemiol 27:493-9. 2006..Several studies investigating this issue with regard to intensive care unit (ICU) patients have probably overestimated, as a result of inappropriate study methods, the part played by NIs in prolonging the length of stay...
- Hand rub consumption and hand hygiene compliance are not indicators of pathogen transmission in intensive care unitsT Eckmanns
Institute of Hygiene and Environmental Medicine, Charite, University Medicine Berlin, Germany
J Hosp Infect 63:406-11. 2006....
- Antibiotic resistance in the southeastern Mediterranean--preliminary results from the ARMed projectM A Borg
Infection Control Unit, St Luke s Hospital, G Mangia MSD08, Malta
Euro Surveill 11:164-7. 2006..They suggest that this is particularly the case in the eastern Mediterranean region where resistance in S. aureus and E. coli seems to be higher than that reported in the other countries of the Mediterranean...
- Antimicrobial resistance in invasive strains of Escherichia coli from southern and eastern Mediterranean laboratoriesM A Borg
Infection Control Unit, Mater Dei Hospital, Msida, Malta
Clin Microbiol Infect 14:789-96. 2008..There is clearly a need for further investigation of potential causes of the significant resistance identified, as well as for strengthening of national and international surveillance initiatives within this region.;..
- The Nottingham Staphylococcus aureus population study: prevalence of MRSA among the elderly in a university hospitalS Hori
Division of Microbiology and Infectious Diseases, Queen s Medical Centre, University Hospital Nottingham, Nottingham, UK
J Hosp Infect 50:25-9. 2002..The repeated finding of a strong association between MRSA colonization and previous ciprofloxacin exposure demands attention and indicates that fluoroquinolones should be used prudently in institutions where MRSA is endemic...