S L J Wijers
Affiliation: Maastricht University
Country: The Netherlands
- Individual thermogenic responses to mild cold and overfeeding are closely relatedSander L J Wijers
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, The Netherlands
J Clin Endocrinol Metab 92:4299-305. 2007..Adaptive thermogenesis is defined as the increase in energy expenditure in response to overfeeding or cold. Large interindividual differences in adaptive thermogenesis have been described...
- Human skeletal muscle mitochondrial uncoupling is associated with cold induced adaptive thermogenesisSander L J Wijers
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, The Netherlands
PLoS ONE 3:e1777. 2008..Therefore we hypothesized that cold-induced adaptive thermogenesis in humans is accompanied by an increase in mitochondrial uncoupling in skeletal muscle...
- Recent advances in adaptive thermogenesis: potential implications for the treatment of obesityS L J Wijers
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
Obes Rev 10:218-26. 2009..In conjunction with recent advances on signal transduction studies, this knowledge makes manipulation of adaptive thermogenesis a more realistic option and thus a pharmacologically interesting target to treat obesity...
- Cold- and overfeeding-induced changes in the human skeletal muscle proteomeSander L J Wijers
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
J Proteome Res 9:2226-35. 2010..The results of this study stress the importance of changes in glycolytic proteins in both cold- and overfeeding-induced adaptive thermogenesis...
- Cold-induced adaptive thermogenesis in lean and obeseSander L J Wijers
NUTRIM School for Nutrition, Toxicology and Metabolism, Department of Human Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
Obesity (Silver Spring) 18:1092-9. 2010..Furthermore, although a large part of the lean subjects counteracted the cold by increasing EE, most obese subjects changed temperature distribution, and therefore, increased insulation...