Jan Willem Voncken

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. pmc Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
    Jan Willem Voncken
    Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 100:2468-73. 2003
  2. doi request reprint Genetic modification of the mouse: general technology - pronuclear and blastocyst injection
    Jan Willem Voncken
    Department of Molecular Genetics, Maastricht University Medical Center, Maastricht, The Netherlands
    Methods Mol Biol 693:11-36. 2011
  3. ncbi request reprint MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1
    Jan Willem Voncken
    Research Institute Growth and Development, Molecular Genetics, Maastricht University, Universiteitssingel 50, 6200 MD, Maastricht, The Netherlands
    J Biol Chem 280:5178-87. 2005
  4. pmc Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
    Marianne Koritzinsky
    Department of Radiation Oncology MAASTRO, GROW Research Institute, University of Maastricht, The Netherlands
    EMBO J 25:1114-25. 2006
  5. ncbi request reprint A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Bone 40:409-18. 2007
  6. pmc Mapping of protein- and chromatin-interactions at the nuclear lamina
    Nard Kubben
    Center for Heart Failure Research, Maastricht, The Netherlands
    Nucleus 1:460-71. 2010

Collaborators

Detail Information

Publications6

  1. pmc Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
    Jan Willem Voncken
    Division of Molecular Genetics, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 100:2468-73. 2003
    ..Importantly, this finding implicates Polycomb-mediated repression of the Cdkn2a locus in early murine development...
  2. doi request reprint Genetic modification of the mouse: general technology - pronuclear and blastocyst injection
    Jan Willem Voncken
    Department of Molecular Genetics, Maastricht University Medical Center, Maastricht, The Netherlands
    Methods Mol Biol 693:11-36. 2011
    ..This chapter describes classic biotechnological methods used to generate mice from modified pre-implantation embryos...
  3. ncbi request reprint MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1
    Jan Willem Voncken
    Research Institute Growth and Development, Molecular Genetics, Maastricht University, Universiteitssingel 50, 6200 MD, Maastricht, The Netherlands
    J Biol Chem 280:5178-87. 2005
    ..This suggests a novel mechanism by which a silenced gene status can be modulated and implicates PcG-mediated repression as a dynamically controlled process...
  4. pmc Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
    Marianne Koritzinsky
    Department of Radiation Oncology MAASTRO, GROW Research Institute, University of Maastricht, The Netherlands
    EMBO J 25:1114-25. 2006
    ..Together, our data indicate that acute and prolonged hypoxia regulates mRNA translation through distinct mechanisms, each with important contributions to hypoxic gene expression...
  5. ncbi request reprint A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Bone 40:409-18. 2007
    ..Our model recapitulates essential steps in osteochondrogenesis and provides a new experimental system to study and ultimately control tissue regeneration in the adult organism...
  6. pmc Mapping of protein- and chromatin-interactions at the nuclear lamina
    Nard Kubben
    Center for Heart Failure Research, Maastricht, The Netherlands
    Nucleus 1:460-71. 2010
    ..Here we summarize and critically discuss recent technology to analyze lamina-protein and-chromatin interactions...