Research Topics
Species | Pieter Jelle VisserSummaryAffiliation: Maastricht University Country: The Netherlands Publications
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Publications
MCI is not a clinically useful conceptPieter Jelle Visser
Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands
Int Psychogeriatr 18:402-9; discussion 409-14. 2006
Characteristics of preclinical Alzheimer's diseasePieter Jelle Visser
Int J Geriatr Psychiatry 17:88-9. 2002
Diagnostic accuracy of the Preclinical AD Scale (PAS) in cognitively mildly impaired subjectsPieter Jelle Visser
Department of Psychiatry and Neuropsychology, Institute of Brain and Behaviour, University of Maastricht, The Netherlands
J Neurol 249:312-9. 2002..Step-wise scoring of the PAS can reduce the number of elaborate or expensive diagnostic procedures considerably...
Mild cognitive impairment subtypes and vascular dementiaPieter Jelle Visser
J Am Geriatr Soc 54:1966-7; author reply 1967-8. 2006
Mild cognitive impairment as predictor for Alzheimer's disease in clinical practice: effect of age and diagnostic criteriaP J Visser
Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
Psychol Med 38:113-22. 2008..We investigated whether the predictive accuracy of mild cognitive impairment (MCI) for Alzheimer-type dementia (AD) in a clinical setting is dependent on age and the definition of MCI used...
Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort studyPieter Jelle Visser
Department of Psychiatry and Neuropsychology, Alzheimer Center Limburg, University of Maastricht, 6200 MD Maastricht, Netherlands
Lancet Neurol 8:619-27. 2009..We investigated the prevalence of a CSF AD profile in patients with SCI, naMCI, or aMCI and the association of this profile with cognitive outcome in each group...
Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease?P J Visser
Department of Psychiatry, University Hospital Maastricht and Alzheimer Centre Limburg, Maastricht, Netherlands
J Neurol Neurosurg Psychiatry 76:1348-54. 2005..Drugs effective in Alzheimer-type dementia have been tested in subjects with mild cognitive impairment (MCI) because these are supposed to have Alzheimer's disease in the predementia stage...
Ten-year risk of dementia in subjects with mild cognitive impairmentPieter Jelle Visser
Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands
Neurology 67:1201-7. 2006..To investigate the 10-year risk of dementia in subjects with mild cognitive impairment (MCI) ages 40 to 85 years...
Diagnosis of preclinical Alzheimer's disease in a clinical settingP J Visser
Department of Psychiatry and Neuropsychology, University of Maastricht, The Netherlands
Int Psychogeriatr 13:411-23. 2001..To this end we investigated whether subjects with preclinical AD could be differentiated from subjects with nonprogressive mild cognitive impairment and from subjects with very mild AD-type dementia...
Medial temporal lobe atrophy predicts Alzheimer's disease in patients with minor cognitive impairmentP J Visser
Institute of Brain and Behavior, Department of Psychiatry, University of Maastricht, Maastricht, The Netherlands
J Neurol Neurosurg Psychiatry 72:491-7. 2002..Quantitative and qualitative methods of assessing the medial temporal lobe were also compared...
Development of screening guidelines and clinical criteria for predementia Alzheimer's disease. The DESCRIPA StudyP J Visser
Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, The Netherlands
Neuroepidemiology 30:254-65. 2008..We also present baseline characteristics of the subjects included. The study was part of the multicentre DESCRIPA project, which is being conducted within the network of the European Alzheimer's Disease Consortium...
Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCIStephanie Vos
Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, The Netherlands
Neurobiol Aging 33:2272-81. 2012..These results provide further support for the use of CSF and magnetic resonance imaging biomarkers to identify prodromal AD...
The predictive value of memory strategies for Alzheimer's disease in subjects with mild cognitive impairmentInez H G B Ramakers
Department of Psychiatry and Neuropsychology Alzheimer Center Limburg, School for Mental Health and Neurosciences, Maastricht University Medical Center, Maastricht, The Netherlands
Arch Clin Neuropsychol 25:71-7. 2010..Prodromal AD is characterized by a decreased use of effortful learning strategies. This finding may have implications for the early detection of AD in MCI subjects and for the development of cognitive training programs...
Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysisLyzel S Elias-Sonnenschein
School of Mental Health and Neuroscience, Alzheimer Center Limburg, Department of Psychiatry and Neuropsychology, Maastricht University Medical Center, Maastricht, The Netherlands
J Neurol Neurosurg Psychiatry 82:1149-56. 2011..The APOE-ε4 allele is the strongest known genetic risk factor for AD. The authors performed a meta-analysis to establish the predictive accuracy of the APOE-ε4 allele for progression from MCI to AD-type dementia...
Predictive accuracy of MCI subtypes for Alzheimer's disease and vascular dementia in subjects with mild cognitive impairment: a 2-year follow-up studyS M C Rasquin
Research Institute Brain and Behavior, Department of Psychiatry and Neuropsychology, University of Maastricht, University Hospital Maastricht, Maastricht, The Netherlands
Dement Geriatr Cogn Disord 19:113-9. 2005..8-100%). DISCUSSION: The subtype 'multiple domain MCI' has high sensitivity in identifying people at risk for developing AD or VaD. The predictive accuracy of the MCI subtypes was similar for both AD and VaD...
Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCIStephanie J B Vos
Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, The Netherlands
Neurology 80:1124-32. 2013....
Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairmentLies Clerx
Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, The Netherlands Electronic address
Neurobiol Aging 34:2003-13. 2013..MTA-score and lateral ventricle volume correlated with CSF beta-amyloid 1-42. We can conclude that volumetric hippocampal measurements are the best predictors of AD conversion in subjects with MCI...
Comparison of International Working Group criteria and National Institute on Aging-Alzheimer's Association criteria for Alzheimer's diseasePieter Jelle Visser
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, The Netherlands
Alzheimers Dement 8:560-3. 2012..Further research is needed to validate the criteria. Modifications are likely to be made before the criteria can be used in daily practice...
New MRI markers for Alzheimer's disease: a meta-analysis of diffusion tensor imaging and a comparison with medial temporal lobe measurementsLies Clerx
Alzheimer Centre Limburg, School for Mental Health and NeuroScience MHeNS, University Medical Centre, Maastricht, The Netherlands
J Alzheimers Dis 29:405-29. 2012..Furthermore, it seems that MD values have somewhat more discriminative power than FA values with higher ES in the frontal, parietal, occipital and temporal lobe...
Characteristics of help-seeking behaviour in subjects with subjective memory complaints at a memory clinic: a case-control studyInez H G B Ramakers
Department of Psychiatry and Neuropsychology, Institute of Brain and Behaviour, Maastricht University, The Netherlands
Int J Geriatr Psychiatry 24:190-6. 2009..Only a subset of these subjects seeks medical attention for these complaints. The aim of the present study was to investigate which factors determine why people with subjective memory complaints (SMC) seek medical attention...
Association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependentHeidi I L Jacobs
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Centre, Limburg, Maastricht University, Maastricht, The Netherlands
Neurobiol Aging 33:201.e1-8. 2012....
Affective symptoms as predictors of Alzheimer's disease in subjects with mild cognitive impairment: a 10-year follow-up studyI H G B Ramakers
Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Alzheimer Centre Limburg, NL 6200 MD Maastricht, The Netherlands
Psychol Med 40:1193-201. 2010..We investigated the predictive accuracy of affective symptoms for AD during a follow-up study in subjects with MCI, and whether the predictive accuracy was modified by age, the presence of amnestic MCI or the length of follow-up...
Predictive value of mild cognitive impairment for dementia. The influence of case definition and ageM A E Baars
Department of Psychiatry and Neuropsychology, School for Public Health and Primary Care CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
Dement Geriatr Cogn Disord 27:173-81. 2009..This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated...
Course of objective memory impairment in non-demented subjects attending a memory clinic and predictors of outcomeP J Visser
Department of Psychiatry and Neuropsychology, Institute of Brain and Behavior, University of Maastricht, Maastricht, The Netherlands
Int J Geriatr Psychiatry 15:363-72. 2000..Predictive accuracy can be increased by including simple measures such as age, the scores on the MMSE and delayed recall, and the degree of functional impairment...
The relation between global and limbic brain volumes on MRI and cognitive performance in healthy individuals across the age rangeD J Tisserand
Maastricht University, Department of Psychiatry and Neuropsychology, P O Box 616, 6200 MD, Maastricht, The Netherlands
Neurobiol Aging 21:569-76. 2000..To conclude, variations in total and limbic brain volumes do not seem predictive for cognitive performance independent of age...
The Association Between APOE ε4 and Alzheimer-type Dementia Among Memory Clinic Patients is Confined to those with a Higher Education. The DESCRIPA StudyAngelique P A Vermeiren
Caphri, Department of Social Medicine, Maastricht University, Maastricht, The Netherlands
J Alzheimers Dis 35:241-6. 2013..81, 95% CI 0.38-1.72, n = 183). This suggests that mechanisms in developing Alzheimer-type dementia may differ between educational groups that raises questions related to Alzheimer-type dementia prevention...
Relationship between genetic risk factors and markers for Alzheimer's disease pathologyLyzel S Elias-Sonnenschein
School for Mental Health and Neuroscience, Alzheimer Centrum Limburg, Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
Biomark Med 6:477-95. 2012..Of all covered genes, only APOE and PICALM showed consistent effects on Aβ but not on tau, while no obvious effects were observed for CLU, CR1, ACE, SORL and MAPT...
Symptoms of preclinical dementia in general practice up to five years before dementia diagnosisInez H G B Ramakers
Department of Psychiatry and Neuropsychology, Institute of Brain and Behavior, Maastricht University, Maastricht, The Netherlands
Dement Geriatr Cogn Disord 24:300-6. 2007..To investigate which symptoms are indicative of preclinical dementia in general practice and whether subjects with preclinical dementia have an increased contact frequency with their general practitioner (GP)...
Epigenetic regulation in the pathophysiology of Alzheimer's diseaseLeonidas Chouliaras
School for Mental Health and NeuroScience MHeNS, Faculty of Health, Medicine and Life Sciences, European Graduate School of Neuroscience EURON, Maastricht University Medical Centre, PO Box 616, 6200 MD Maastricht, The Netherlands
Prog Neurobiol 90:498-510. 2010..Research on earlier stages of the disease could provide more insight into its underlying pathophysiology, possibly contributing to the establishment of early diagnosis and the development of more effective treatment strategies...
The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathologyI H G B Ramakers
Department of Psychiatry and Neuropsychology, Institute of Brain and Behaviour, Maastricht University, Maastricht, The Netherlands
Dement Geriatr Cogn Disord 26:101-8. 2008..We investigated whether the effect of the APOE genotype on memory in subjects with MCI was dependent on age and underlying Alzheimer disease (AD) pathology...
Role of cognitive testing in disease modifying AD trialsP J Visser
Department of Psychiatry and Neuropsychology, University of Maastricht, The Netherlands
J Nutr Health Aging 10:131-2; discussion 132-3. 2006..The selection of these tests would depend on a number of study characteristics such as the inclusion criteria and the length of follow-up...
Diagnostic and economic evaluation of new biomarkers for Alzheimer's disease: the research protocol of a prospective cohort studyRon L H Handels
Alzheimer Centre Limburg, School for Mental Health and NeuroScience MHeNS, University Medical Centre, P O Box 5800, 6202, AZ Maastricht, The Netherlands
BMC Neurol 12:72. 2012....
The effect of the APOE-epsilon4 allele and ACE-I/D polymorphism on cognition during a two-year follow-up in first-ever stroke patientsA M J J Bour
Department of Clinical Neurophysiology, Maastricht University Medical Center, Maastricht, The Netherlands
Dement Geriatr Cogn Disord 29:534-42. 2010..Objective: To study the influence of the APOE-epsilon4 allele and the ACE-I/D polymorphism on cognitive functioning after stroke...
Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairmentEsther S C Korf
Department of Neurology and Alzheimer Center, Vrije Universiteit Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Neurology 63:94-100. 2004..Although detailed volumetric MRI assessment of medial temporal lobe atrophy (MTA) can predict dementia in patients with mild cognitive impairment (MCI), it is not easily applied to routine clinical practice...
Medial temporal lobe atrophy and APOE genotype do not predict cognitive improvement upon treatment with rivastigmine in Alzheimer's disease patientsPieter Jelle Visser
Department of Neurology, Alzheimer Centre, VU Medisch Centrum, Amsterdam, The Netherlands
Dement Geriatr Cogn Disord 19:126-33. 2005..Only a subgroup of subjects with probable AD shows cognitive improvement after treatment with cholinesterase inhibitors...
