Jim Van Os

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint The impact of subclinical psychosis on the transition from subclinicial mania to bipolar disorder
    Nil Kaymaz
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO BOX 616 DRT 10, 6200 MD Maastricht, The Netherlands
    J Affect Disord 98:55-64. 2007
  2. ncbi request reprint No ecological effect modification of the association between negative life experiences and later psychopathology in adolescence: A longitudinal community study in adolescents
    Nicole Gunther
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands
    Eur Psychiatry 22:296-304. 2007
  3. pmc Evidence that onset of psychosis in the population reflects early hallucinatory experiences that through environmental risks and affective dysregulation become complicated by delusions
    Feikje Smeets
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    Schizophr Bull 38:531-42. 2012
  4. pmc Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study
    Rebecca Kuepper
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Center, Maastricht, Netherlands
    BMJ 342:d738. 2011
  5. pmc Executive function does not predict coping with symptoms in stable patients with a diagnosis of schizophrenia
    Maarten Bak
    Dept Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    BMC Psychiatry 8:39. 2008
  6. pmc Bipolar disorder and dopamine dysfunction: an indirect approach focusing on tardive movement syndromes in a naturalistic setting
    Inge van Rossum
    Eli Lilly Nederland, Medical Department, Houten, The Netherlands
    BMC Psychiatry 9:16. 2009
  7. pmc Are women better mindreaders? Sex differences in neural correlates of mentalizing detected with functional MRI
    Sören Krach
    Department of Psychiatry und Psychotherapy, Section of Neuroimaging, Philipps University Marburg, Rudolf Bultmann Strasse 8, D 35039 Marburg, Germany
    BMC Neurosci 10:9. 2009
  8. doi request reprint 'Salience syndrome' replaces 'schizophrenia' in DSM-V and ICD-11: psychiatry's evidence-based entry into the 21st century?
    J van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    Acta Psychiatr Scand 120:363-72. 2009
  9. ncbi request reprint Confirmation of synergy between urbanicity and familial liability in the causation of psychosis
    Jim Van Os
    Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Am J Psychiatry 161:2312-4. 2004
  10. ncbi request reprint The environment and schizophrenia: the role of cannabis use
    Cecile Henquet
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Schizophr Bull 31:608-12. 2005

Detail Information

Publications139 found, 100 shown here

  1. ncbi request reprint The impact of subclinical psychosis on the transition from subclinicial mania to bipolar disorder
    Nil Kaymaz
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO BOX 616 DRT 10, 6200 MD Maastricht, The Netherlands
    J Affect Disord 98:55-64. 2007
    ..Little is known, however, about how these subclinical population phenotypes co-vary with and impact on each other...
  2. ncbi request reprint No ecological effect modification of the association between negative life experiences and later psychopathology in adolescence: A longitudinal community study in adolescents
    Nicole Gunther
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands
    Eur Psychiatry 22:296-304. 2007
    ..The aim of the study was to examine the potential contribution of exposure to bullying and adverse life events to the development of psychopathology in adolescents, and possible effect modification by neighbourhood social capital...
  3. pmc Evidence that onset of psychosis in the population reflects early hallucinatory experiences that through environmental risks and affective dysregulation become complicated by delusions
    Feikje Smeets
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    Schizophr Bull 38:531-42. 2012
    ....
  4. pmc Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study
    Rebecca Kuepper
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Center, Maastricht, Netherlands
    BMJ 342:d738. 2011
    ....
  5. pmc Executive function does not predict coping with symptoms in stable patients with a diagnosis of schizophrenia
    Maarten Bak
    Dept Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    BMC Psychiatry 8:39. 2008
    ....
  6. pmc Bipolar disorder and dopamine dysfunction: an indirect approach focusing on tardive movement syndromes in a naturalistic setting
    Inge van Rossum
    Eli Lilly Nederland, Medical Department, Houten, The Netherlands
    BMC Psychiatry 9:16. 2009
    ..An indirect approach to examine this issue was developed, focusing on associations between dopamine proxy measures observed in BD (dopamine-related clinical traits using tardive movement syndromes as dopamine proxy measure of reference)...
  7. pmc Are women better mindreaders? Sex differences in neural correlates of mentalizing detected with functional MRI
    Sören Krach
    Department of Psychiatry und Psychotherapy, Section of Neuroimaging, Philipps University Marburg, Rudolf Bultmann Strasse 8, D 35039 Marburg, Germany
    BMC Neurosci 10:9. 2009
    ..Groups of men (n = 12) and women (n = 12) interacted in an iterated classical prisoner's dilemma forced choice situation with alleged human and computer partners who were outside the scanner...
  8. doi request reprint 'Salience syndrome' replaces 'schizophrenia' in DSM-V and ICD-11: psychiatry's evidence-based entry into the 21st century?
    J van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    Acta Psychiatr Scand 120:363-72. 2009
    ..Japan was the first country to abandon the 19th century term of 'mind-splitting disease' (schizophrenia). Revisions of DSM and ICD are forthcoming. Should the rest of the world follow Japan's example?..
  9. ncbi request reprint Confirmation of synergy between urbanicity and familial liability in the causation of psychosis
    Jim Van Os
    Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Am J Psychiatry 161:2312-4. 2004
    ..This study replicated a previous report that there may be substantial synergism between urbanicity (a proxy environmental risk factor) and familial clustering of psychotic disorder (a proxy genetic risk factor)...
  10. ncbi request reprint The environment and schizophrenia: the role of cannabis use
    Cecile Henquet
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Schizophr Bull 31:608-12. 2005
    ..Potential new methods to directly link genetic liability to the effects of cannabis are discussed...
  11. ncbi request reprint Schizophrenia
    Jim Van Os
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, Netherlands
    Lancet 374:635-45. 2009
    ..Although current treatments provide control rather than cure, long-term hospitalisation is not required and prognosis is better than traditionally assumed...
  12. ncbi request reprint [Psychosis: from diagnosis to syndrome]
    Jim Van Os
    Universitair Medisch Centrum Maastricht, afd Psychiatrie en Psychologie, Maastricht, The Netherlands
    Ned Tijdschr Geneeskd 154:A1874. 2010
    ..A better understanding of the biological mechanisms and the psychosocial factors underlying psychotic disorders may contribute to new treatments...
  13. ncbi request reprint Commentary on residential location papers by Whitfield et al. (2005) and Willemsen et al. (2005)
    Jim Van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Network, Maastricht University, Maastricht, The Netherlands
    Twin Res Hum Genet 8:318-9. 2005
  14. ncbi request reprint [A psychosis proneness-persistence-impairment model of psychotic disorders]
    J van Os
    vakgroep Psychiatrie, UMC Maastricht, Universiteit Maastricht, Maastricht
    Tijdschr Psychiatr 50:77-83. 2008
    ..Whether or not this will lead to a poor prognosis in terms of persistence and clinical need will depend on the interaction between environmental exposure and genetic risk...
  15. pmc Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions
    Jim Van Os
    Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, EURON, SEARCH, Maastricht, The Netherlands
    Schizophr Bull 34:1066-82. 2008
    ....
  16. doi request reprint Evidence that the Two-Way Communication Checklist identifies patient-doctor needs discordance resulting in better 6-month outcome
    J van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Acta Psychiatr Scand 118:322-6. 2008
    ..To assess an intervention aimed at reducing patient-professional carer needs discordance...
  17. doi request reprint A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder
    J van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Psychol Med 39:179-95. 2009
    ....
  18. ncbi request reprint The social, psychopathological and consumer context of rate of symptom improvement in acute mania
    Jim Van Os
    Dept of Psychiatry and Neuropsychology, Maastricht University, European Graduate School of Neuroscience, PO Box 616, 6200, MD, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 42:631-8. 2007
    ..Knowledge of moderators of symptom improvement over time in acute mania improves predictability of individual patient outcomes. This study attempted to identify such moderators of the rate of symptom improvement...
  19. pmc Toward a world consensus on prevention of schizophrenia
    Jim Van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Dialogues Clin Neurosci 7:53-67. 2005
    ..Gaining insight into the cognitive and biological factors that drive the dimensional variation, including therapeutic interventions, is arguably more useful than sterile dichotomous prediction models...
  20. ncbi request reprint Validation of remission criteria for schizophrenia
    Jim Van Os
    Department of Psychiatry and Neuropsychology, Maastricht University, P O Box 616 DRT 10, 6200 MD Maastricht, The Netherlands
    Am J Psychiatry 163:2000-2. 2006
    ..With longitudinal data of a representative patient group (N=317; median follow-up: 1,132 days), validity of the symptomatic remission criterion was investigated...
  21. ncbi request reprint Standardized remission criteria in schizophrenia
    J van Os
    Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands
    Acta Psychiatr Scand 113:91-5. 2006
    ..Recent work has focussed on schizophrenia as a 'deficit' state but little attention has been paid to defining illness plasticity in terms of symptomatic remission...
  22. ncbi request reprint Improvements in stable patients with psychotic disorders switched from oral conventional antipsychotics therapy to long-acting risperidone
    Jim Van Os
    Maastricht University, Maastricht, The Netherlands
    Int Clin Psychopharmacol 19:229-32. 2004
    ....
  23. ncbi request reprint Is there a continuum of psychotic experiences in the general population?
    Jim Van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Epidemiol Psichiatr Soc 12:242-52. 2003
    ..This paper reviews evidence for the continuity of psychotic symptoms with normal experiences, focusing on the symptoms of hallucinations and delusions...
  24. ncbi request reprint Self-reported psychosis-like symptoms and the continuum of psychosis
    J van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 34:459-63. 1999
    ..This study examined the hypothesis that the severity of positive psychotic symptoms increases from normality, through depression/anxiety states to clinical psychosis...
  25. ncbi request reprint Strauss (1969) revisited: a psychosis continuum in the general population?
    J van Os
    Department of Psychiatry and Neuropsychology, Maastricht University, European Graduate School of Neuroscience, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Schizophr Res 45:11-20. 2000
    ..The boundaries of the psychosis phenotype may extend beyond the clinical concept of schizophrenia...
  26. ncbi request reprint Cannabis use and psychosis: a longitudinal population-based study
    J van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 156:319-27. 2002
    ..001). Results confirm previous suggestions that cannabis use increases the risk of both the incidence of psychosis in psychosis-free persons and a poor prognosis for those with an established vulnerability to psychotic disorder...
  27. ncbi request reprint Does the urban environment independently increase the risk for both negative and positive features of psychosis?
    Jim Van Os
    Department of Psychiatry and Neuropsychology, Maastricht University, European Graduate School of Neuroscience, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 37:460-4. 2002
    ..Psychotic disorders are more common in urban environments. It is not known whether the increase in risk applies to both the positive and negative dimensions of psychosis...
  28. ncbi request reprint 2-COM: an instrument to facilitate patient-professional communication in routine clinical practice
    J van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Acta Psychiatr Scand 106:446-52. 2002
    ..A simple patient-completed self-report instrument may facilitate patient-professional carer communication...
  29. ncbi request reprint The ecogenetics of schizophrenia: a review
    J van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Schizophr Res 32:127-35. 1998
    ..With the advent of molecular genetics, further knowledge about possible genotype-environment interactions is urgently required in order to develop and improve strategies for the prevention and early treatment of schizophrenia...
  30. ncbi request reprint Do urbanicity and familial liability coparticipate in causing psychosis?
    Jim Van Os
    Department of Psychiatry and Neuropshchology, azM Mondriaan Riagg RIBW Vijverdal Academic Centre, EURON, Maastricht University, The Netherlands
    Am J Psychiatry 160:477-82. 2003
    ..The urban environment and familial liability are risk factors for psychotic illness, but it is not known whether a biological synergism exists between these two proxy causes...
  31. ncbi request reprint The environment and schizophrenia
    Jim Van Os
    European Graduate School for Neuroscience, SEARCH, Maastricht University Medical Centre, 6200 MD Maastricht, The Netherlands
    Nature 468:203-12. 2010
    ..Longitudinal research is needed to uncover gene-environment interplay that determines how expression of vulnerability in the general population may give rise to more severe psychopathology...
  32. ncbi request reprint Evaluation of the Two-Way Communication Checklist as a clinical intervention. Results of a multinational, randomised controlled trial
    Jim Van Os
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Br J Psychiatry 184:79-83. 2004
    ..Patients and doctors often have divergent views on care needs...
  33. ncbi request reprint Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: an analysis of patient-sibling and sibling-control pairs
    Rene S Kahn
    Department of Psychiatry and Psychology, Maastricht University Medical Centre, PO Box 616
    Arch Gen Psychiatry 68:138-47. 2011
    ..Individual differences in cannabis sensitivity may be associated with genetic risk for psychotic disorder...
  34. doi request reprint Are psychiatric diagnoses of psychosis scientific and useful? The case of schizophrenia
    Jim Van Os
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    J Ment Health 19:305-17. 2010
    ..Furthermore, the existence of two separate diagnostic systems in psychiatry, DSM and ICD, produces a bias that is conservative rather than anti-conservative, reducing the probability of non-cosmetic change...
  35. ncbi request reprint Psychosis research at Maastricht University, The Netherlands
    Jim Van Os
    Department of Psychiatry and Neuropsychology, Maastricht University, The Netherlands
    Br J Psychiatry 183:559-60. 2003
  36. ncbi request reprint The catechol-O-methyl transferase Val158Met polymorphism and experience of reward in the flow of daily life
    Marieke Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Neuropsychopharmacology 33:3030-6. 2008
    ..Genetic moderation of ecological measures of reward experience is hypothesized to be of major relevance to the development of various behavioral disorders, including depression and addiction...
  37. doi request reprint COMT Val158Met-stress interaction in psychosis: role of background psychosis risk
    Dina Collip
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, School for Mental Health and NeuroScience MHeNS Maastricht University, Maastricht, The Netherlands
    CNS Neurosci Ther 17:612-9. 2011
    ....
  38. ncbi request reprint The psychology of psychiatric genetics: evidence that positive emotions in females moderate genetic sensitivity to social stress associated with the BDNF Val-sup-6-sup-6Met polymorphism
    Marieke Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    J Abnorm Psychol 117:699-704. 2008
    ..Interdisciplinary research in psychology and psychiatric genetics may lead to the improvement of treatment choices in stress-related disorders...
  39. ncbi request reprint Identifying at-risk states beyond positive symptoms: a brief task assessing how neurocognitive impairments impact on misrepresentation of the social world through blunted emotional appraisal
    Mariana Galdos
    Department of Psychiatry and Neuropsychology, Maastricht University Medical Centre, The Netherlands
    Rev Bras Psiquiatr 33:s175-96. 2011
    ..Early intervention efforts would be served by further elucidation of this mechanism...
  40. doi request reprint Neurocognitive functioning as intermediary phenotype and predictor of psychosocial functioning across the psychosis continuum: studies in schizophrenia and bipolar disorder
    Nienke Jabben
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    J Clin Psychiatry 71:764-74. 2010
    ....
  41. ncbi request reprint Evidence for a relationship between mentalising deficits and paranoia over the psychosis continuum
    Dagmar Versmissen
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO BOX 616 VIJV, 6200 MD Maastricht, The Netherlands
    Schizophr Res 99:103-10. 2008
    ..This study wanted to assess an aspect of mentalising in four groups with different levels of psychosis vulnerability, and to examine associations between mentalising and symptoms of psychosis...
  42. ncbi request reprint Transition from stress sensitivity to a depressive state: longitudinal twin study
    Marieke Wichers
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Vijverdalseweg 1, Concorde Building, Maastricht, The Netherlands
    Br J Psychiatry 195:498-503. 2009
    ..Daily-life stress sensitivity is associated with depression, but prospective data are lacking...
  43. doi request reprint Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up
    Ruud van Winkel
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    Arch Gen Psychiatry 68:148-57. 2011
    ..Individual differences exist in sensitivity to the psychotomimetic effect of cannabis; the molecular genetic basis underlying differential sensitivity remains elusive...
  44. ncbi request reprint Explaining transitions over the hypothesized psychosis continuum
    Lydia Krabbendam
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, Maastricht, University, The Netherlands
    Aust N Z J Psychiatry 39:180-6. 2005
    ....
  45. ncbi request reprint FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma
    Dina Collip
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    Br J Psychiatry 202:261-8. 2013
    ..FK506 binding protein 5 (FKBP5) has repeatedly been shown to be a critical determinant of post-traumatic stress disorder (PTSD) and depression following childhood trauma...
  46. pmc COMT Val158Met genotype selectively alters prefrontal [18F]fallypride displacement and subjective feelings of stress in response to a psychosocial stress challenge
    Dennis Hernaus
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, School for Mental Health and NeuroScience MHeNS Maastricht University, Maastricht, The Netherlands
    PLoS ONE 8:e65662. 2013
    ..Implications of these results for stress-related psychopathology and models of dopaminergic functioning are discussed. ..
  47. pmc Altered transfer of momentary mental states (ATOMS) as the basic unit of psychosis liability in interaction with environment and emotions
    Johanna T W Wigman
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    PLoS ONE 8:e54653. 2013
    ....
  48. ncbi request reprint Genetic risk of depression and stress-induced negative affect in daily life
    Marieke Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Vijverdalseweg 1, Concorde Building, Maastricht, The Netherlands
    Br J Psychiatry 191:218-23. 2007
    ..A bias to develop negative affect in response to daily life stressors may be an important depression endophenotype, but remains difficult to assess...
  49. ncbi request reprint Do different psychotic experiences differentially predict need for care in the general population?
    Maarten Bak
    Department of Psychiatry, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, The Netherlands
    Compr Psychiatry 46:192-9. 2005
    ..The pathway from subclinical psychotic experiences to need for care may depend on type of psychotic experience, level of associated distress, and previous experience of psychosis...
  50. pmc AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder
    Ruud van Winkel
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, European Graduate School of Neuroscience EURON, South Limburg Mental Health Research and Teaching Network SEARCH, Maastricht University Medical Centre, Maastricht, The Netherlands
    Neuropsychopharmacology 36:2529-37. 2011
    ..The results suggest that long-term changes in cognition may mediate the risk-increasing effect of the AKT1 × cannabis interaction on psychotic disorder...
  51. pmc The wider social environment and changes in self-reported quality of life in the transition from late childhood to early adolescence: a cohort study
    Marjan Drukker
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    BMC Public Health 6:133. 2006
    ..Therefore, the contribution of the neighbourhood environment to adolescents' quality of life and the course of these effects during the period of transition from childhood to early adolescence was examined...
  52. pmc The cumulative needs for care monitor: a unique monitoring system in the south of the Netherlands
    Marjan Drukker
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, School for Mental Health and NeuroScience MHeNS, Maastricht University, Vijverdal, 6200 MD Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 45:475-85. 2010
    ..The present paper describes the methods of the cumulative needs for care monitor (CNCM), a monitoring system in operation in a geographically defined area...
  53. doi request reprint Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia
    Petra Habets
    Department of Psychiatry and Psychology, School for Mental Health and Neuroscience, European Graduate School of Neuroscience, Maastricht University Medical Centre, Vijv1 Maastricht, The Netherlands
    Biol Psychiatry 69:487-94. 2011
    ..This study examined the impact of two environmental exposures associated with both schizophrenia and magnetic resonance imaging (MRI) cerebral alterations in models of cerebral cortical thickness...
  54. ncbi request reprint Development of depressed mood predicts onset of psychotic disorder in individuals who report hallucinatory experiences
    Lydia Krabbendam
    Department of Psychiatry and Neuropsychology, Maastricht University, The Netherlands
    Br J Clin Psychol 44:113-25. 2005
    ..This study examined the hypothesis that the risk for onset of psychotic disorder in individuals with self-reported hallucinatory experiences would be higher in those who subsequently developed depressed mood than in those who did not...
  55. ncbi request reprint Evidence that moment-to-moment variation in positive emotions buffer genetic risk for depression: a momentary assessment twin study
    Marieke C Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Acta Psychiatr Scand 115:451-7. 2007
    ..It was investigated whether positive affect (PA) buffers negative affect (NA) reactivity in response to stress and whether PA moderates the genetic predisposition to negative affect reactivity...
  56. doi request reprint Susceptibility to depression expressed as alterations in cortisol day curve: a cross-twin, cross-trait study
    Marieke C Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Vijverdalseweg 1, Concorde Building, Maastricht, Netherlands
    Psychosom Med 70:314-8. 2008
    ..Alteration of diurnal secretion of cortisol is a possible endophenotype of depression, as depressed patients show alterations in cortisol dynamics over the day...
  57. pmc Emotional experience in negative symptoms of schizophrenia--no evidence for a generalized hedonic deficit
    Margreet Oorschot
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, Maastricht University, PO BOX 616 VIJV, 6200 MD, Maastricht, The Netherlands
    Schizophr Bull 39:217-25. 2013
    ..This study investigated emotional experience and social behavior in the realm of daily life in a sample of patients with schizophrenia and schizoaffective disorder, stratified by level of negative symptoms...
  58. pmc Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction
    Leonidas Chouliaras
    School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, European Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    Neurobiol Aging 33:1672-81. 2012
    ..These findings suggest a crucial role for DNA methylation in hippocampal aging and in the mediation of the beneficial effects of CR on aging...
  59. doi request reprint A time-lagged momentary assessment study on daily life physical activity and affect
    Marieke Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Health Psychol 31:135-44. 2012
    ..The current study examined the effects of physical activity on affective state. A primary and within-study replication sample was derived from twin pairs...
  60. doi request reprint Meta-analysis of MTHFR gene variants in schizophrenia, bipolar disorder and unipolar depressive disorder: evidence for a common genetic vulnerability?
    Odette L J Peerbooms
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, European Graduate School of Neuroscience, South Limburg Mental Health Research and Teaching Network, Maastricht University, Maastricht, The Netherlands
    Brain Behav Immun 25:1530-43. 2011
    ..This study provides evidence for shared genetic vulnerability for SZ, BPD and UDD mediated by MTHFR 677TT genotype, which is in line with epigenetic involvement in the pathophysiology of these psychiatric disorders...
  61. pmc Affectively salient meaning in random noise: a task sensitive to psychosis liability
    Mariana Galdos
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, Maastricht, The Netherlands
    Schizophr Bull 37:1179-86. 2011
    ..The data suggest that the white noise task may be sensitive to psychometric and familial vulnerability for psychosis associated with alterations in top-down processing and/or salience attribution...
  62. pmc A real-life observational study of the effectiveness of FACT in a Dutch mental health region
    Marjan Drukker
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO Box 616, location Vijverdal 6200 MD Maastricht, The Netherlands
    BMC Psychiatry 8:93. 2008
    ..The effectiveness of FACT was compared with standard care, with a particular focus on possible moderating effects of patient characteristics within the case mix in FACT...
  63. pmc Diagnostic considerations regarding pediatric delirium: a review and a proposal for an algorithm for pediatric intensive care units
    Jan N M Schieveld
    Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, European Graduate School of Neuroscience, SEARCH, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands
    Intensive Care Med 35:1843-9. 2009
    ..If delirium is not diagnosed, it is unlikely that any effort will be made to reverse it. Given evidence for under-diagnosis, tools that aid recognition are required...
  64. ncbi request reprint Is processing speed predictive of functional outcome in psychosis?
    Nienke Jabben
    Department of Psychiatry and Neuropsychology, Maastricht University, P O BOX 616 VIJV, 6200 MD, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 43:437-44. 2008
    ..To investigate the contribution of processing speed in the prediction of various domains of outcome in psychosis...
  65. ncbi request reprint Residential instability in socioeconomically deprived neighbourhoods, good or bad?
    Marjan Drukker
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, P O Box 616 PAR45, 6200 MD Maastricht, The Netherlands
    Health Place 11:121-9. 2005
    ..Thus, when accounting for interaction effects, residential instability appeared to protect against negative effects of neighbourhood poverty and, therefore, may be beneficial for residents' quality of life...
  66. ncbi request reprint Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression
    Nele Jacobs
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands
    Arch Gen Psychiatry 63:989-96. 2006
    ....
  67. doi request reprint Emotional experience and estimates of D2 receptor occupancy in psychotic patients treated with haloperidol, risperidone, or olanzapine: an experience sampling study
    Johan Lataster
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Center, Maastricht, The Netherlands
    J Clin Psychiatry 72:1397-404. 2011
    ..The present study investigates the differential effects of relatively tight versus looser binding drugs on the experience of emotions in the realm of daily life...
  68. doi request reprint Impairment of self-monitoring: part of the endophenotypic risk for psychosis
    Dagmar Versmissen
    Department of Psychiatry and Neuropsychology, Maastricht University, PO BOX 616 VIJV, 6200 MD Maastricht, The Netherlands
    Br J Psychiatry Suppl 51:s58-62. 2007
    ..A disorder of self-monitoring may underlie the positive symptoms of psychosis. The cognitive mechanisms associated with these symptoms may also be detectable in individuals at risk of psychosis...
  69. pmc Systematic monitoring of needs for care and global outcomes in patients with severe mental illness
    Marjan Drukker
    Department of Psychiatry and Psychology, School for Mental Health and NeuroScience MHeNS, Maastricht University, The Netherlands
    BMC Psychiatry 10:36. 2010
    ....
  70. ncbi request reprint An experimental study of catechol-o-methyltransferase Val158Met moderation of delta-9-tetrahydrocannabinol-induced effects on psychosis and cognition
    Cecile Henquet
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Neuropsychopharmacology 31:2748-57. 2006
    ..The association between cannabis and psychosis may represent higher order gene-environment and gene-gene interactions...
  71. pmc Subjective experience of cognitive failures as possible risk factor for negative symptoms of psychosis in the general population
    Stefanie Pfeifer
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO BOX 616 VIJV1, 6200 MD, Maastricht, The Netherlands
    Schizophr Bull 35:766-74. 2009
    ..The aim of this study was to examine whether proneness to subjective cognitive failure (cognitive based mistakes) increases the risk for the development of symptoms of psychosis and to what degree any association was familial...
  72. ncbi request reprint The incidence and outcome of subclinical psychotic experiences in the general population
    Manon Hanssen
    Department of Psychiatry and Neuropsychology, Universiteit Maastricht, The Netherlands
    Br J Clin Psychol 44:181-91. 2005
    ..To examine the incidence and 2-year stability and outcome of subclinical psychotic experiences in the general population...
  73. ncbi request reprint The BDNF Val(66)Met x 5-HTTLPR x child adversity interaction and depressive symptoms: An attempt at replication
    Marieke Wichers
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Am J Med Genet B Neuropsychiatr Genet 147:120-3. 2008
    ..Higher order interaction effects involving BDNF Val(66)Met, 5-HTTLPR and childhood adversity may contribute to the etiology of depressive illness...
  74. ncbi request reprint Investigating the association between neurocognition and psychosis in bipolar disorder: further evidence for the overlap with schizophrenia
    Nienke Jabben
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Bipolar Disord 11:166-77. 2009
    ..In this study, we investigated whether this model can be extended to bipolar disorder by testing the hypothesis that neurocognitive functioning is inversely related to positive psychotic symptoms in bipolar disorder...
  75. ncbi request reprint MTHFR and risk of metabolic syndrome in patients with schizophrenia
    Ruud van Winkel
    Department of Psychiatry and Neuropsychology, EURON, South Limburg Mental Health Research and Teaching Network, Maastricht University Medical Centre, PO Box 616, 6200 MD Maastricht, The Netherlands
    Schizophr Res 121:193-8. 2010
    ..Meta-analyses have implicated polymorphisms in MTHFR, encoding a critical enzyme in folate and homocysteine metabolism, in both schizophrenia and CVD...
  76. ncbi request reprint Early expression of negative/disorganized symptoms predicting psychotic experiences and subsequent clinical psychosis: a 10-year study
    Maria de Gracia Dominguez
    Department of Psychiatry and Neuropsychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, The Netherlands
    Am J Psychiatry 167:1075-82. 2010
    ..The epidemiological predictions of this model were tested...
  77. ncbi request reprint Hearing impairment and psychosis revisited
    Viviane Thewissen
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, The Netherlands
    Schizophr Res 76:99-103. 2005
    ..0, 95% CI: 1.4, 6.2) These results confirm previous findings of an association between hearing impairments and psychosis and show that this association can also be found prospectively in a nonclinical population...
  78. ncbi request reprint A community study of psychosocial functioning and weight in young children and adolescents
    Marjan Drukker
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, PO Box 616, Maastricht 6200 MD, The Netherlands
    Int J Pediatr Obes 4:91-7. 2009
    ..The present study investigated the relationship between weight status and psychosocial dysfunctioning in children of two different age groups (5-6 and 13-14 years)...
  79. pmc Do symptom dimensions or categorical diagnoses best discriminate between known risk factors for psychosis?
    Judith Allardyce
    Dept of Psychiatry and Neuropsychology, Maastricht University, P O Box 616 location DOT10, 6200 MD Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 42:429-37. 2007
    ..Then, assess the comparative usefulness of the dimensional and categorical representations of psychosis in discriminating between demographic and pre-morbid risk factors...
  80. ncbi request reprint Are cognitive impairments associated with sensitivity to stress in schizophrenia? An experience sampling study
    Inez Myin-Germeys
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, The Netherlands
    Am J Psychiatry 159:443-9. 2002
    ..Patients with a diagnosis of schizophrenia display cognitive impairments and abnormal sensitivity to stress. However, little is known about the relationship between these two endophenotypes...
  81. ncbi request reprint Sex differences in psychosis: normal or pathological?
    Janneke Spauwen
    Department of Psychiatry and Neuropsychology, Maastricht University, European Graduate School of Neuroscience, PO BOX 616 DRT 10, 6200 MD Maastricht, The Netherlands
    Schizophr Res 62:45-9. 2003
    ..The interpretation of this key epidemiological finding crucially depends on whether similar age-related sex differences exist in the expression of associated, subclinical psychosis-like experiences...
  82. ncbi request reprint Mediators of neighbourhood socioeconomic deprivation and quality of life
    Marjan Drukker
    Dept of Psychiatry and Neuropsychology, South Limburg Mental Health Research Network, EURON, Maastricht University, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 38:698-706. 2003
    ..We examined associations between neighbourhood socioeconomic deprivation and health-related quality of life, and estimated the mediating effects of individual-level lifestyle, housing, and perception of the neighbourhood environment...
  83. ncbi request reprint Momentary assessment research in psychosis
    Margreet Oorschot
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands
    Psychol Assess 21:498-505. 2009
    ..Finally, the study of symptomatic variability may fuel new research into psychological models and treatment of psychosis and the study of the person-environment interplay may foster new Gene x Environment interaction studies...
  84. ncbi request reprint Does urbanicity shift the population expression of psychosis?
    Janneke Spauwen
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, P O Box 616 DRT 10, 6200 MD Maastricht, The Netherlands
    J Psychiatr Res 38:613-8. 2004
    ..Other causal influences may be required to make the transition to schizophrenia in adult life...
  85. doi request reprint Are psychotic psychopathology and neurocognition orthogonal? A systematic review of their associations
    Maria de Gracia Dominguez
    Department of Psychiatry and Neuropsychology, Maastricht University, The Netherlands
    Psychol Bull 135:157-71. 2009
    ..This association suggests that differential latent cerebral mechanisms underlie the cluster of disorganized and negative symptoms versus that of positive and affective symptoms...
  86. ncbi request reprint Determinants of occurrence and recovery from hallucinations in daily life
    Philippe Delespaul
    Maastricht University, Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 37:97-104. 2002
    ..Data related to the dynamics of hallucinatory experiences of patients suffering from schizophrenia are scarce. Detecting antecedent conditions and coping strategies may aid development of targeted psychological interventions...
  87. ncbi request reprint Children's mental health service use, neighbourhood socioeconomic deprivation, and social capital
    Jikke van der Linden
    Dept of Psychiatry and Neuropsychology, EURON, South Limburg Mental Health Research Network, Maastricht University, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 38:507-14. 2003
    ..e. informal social control, social cohesion and trust) on children's mental health service use, independent of individual level confounders...
  88. ncbi request reprint MTHFR genotype and differential evolution of metabolic parameters after initiation of a second generation antipsychotic: an observational study
    Ruud van Winkel
    Department of Psychiatry and Neuropsychology, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands
    Int Clin Psychopharmacol 25:270-6. 2010
    ..A1298C allele carriers consistently displayed the most unfavorable evolution of metabolic parameters. Thus, MTHFR A1298C genotype may explain part of the individual liability to metabolic disturbances in patients with schizophrenia...
  89. ncbi request reprint Can the social environment cause schizophrenia?
    Jim Van Os
    Department of Psychiatry and Neuropsychology, azM Mondriaan Riagg Vijverdal Academic Centre, Maastricht University, European Graduate School of Neuroscience, Maastricht, The Netherlands
    Br J Psychiatry 182:291-2. 2003
  90. pmc Psychosis risk as a function of age at onset: a comparison between early- and late-onset psychosis in a general population sample
    Sebastian Kohler
    Department of Psychiatry and Neuropsychology, Sth Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, P O BOX 616 VIJV, 6200, MD, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 42:288-94. 2007
    ..The aims of this study were to calculate the incidence of non-affective, non-organic psychotic symptoms across the life span and to explore the contribution of different sets of risk factors in relation to age at onset...
  91. ncbi request reprint Evidence that the urban environment specifically impacts on the psychotic but not the affective dimension of bipolar disorder
    Nil Kaymaz
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, P O Box 616 DRT 10, 6200 MD, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 41:679-85. 2006
    ..It was hypothesised, therefore, that any effect of urbanicity on the bipolar phenotype would be moderated by comorbid psychotic symptoms...
  92. ncbi request reprint Childhood trauma and emotional reactivity to daily life stress in adult frequent attenders of general practitioners
    Jean Paul Glaser
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    J Psychosom Res 61:229-36. 2006
    ..However, not much is known about the impact of a history of trauma on moment-to-moment emotions and experiences in the flow of daily life. The relationship between CT and emotional reactivity to daily life stress was investigated...
  93. ncbi request reprint Sex differences in symptoms of psychosis in a non-selected, general population sample
    Nadja Maric
    Department of Psychiatry and Neuropsychology, azM Mondriaan Riagg RIBW Vijverdal Academic Centre, European Graduate School of Neuroscience, Maastricht University, P O Box 616 DRT 10, 6200 MD Maastricht, The Netherlands
    Schizophr Res 63:89-95. 2003
    ..Little is known about sex differences in psychosis beyond the borders of clinical disorder...
  94. ncbi request reprint Income inequality at neighbourhood level and quality of life--a contextual analysis
    Marjan Drukker
    Dept of Psychiatry and Neuropsychology South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 39:457-63. 2004
    ..Associations were examined between neighbourhood income inequality and neighbourhood socioeconomic deprivation on the one hand and (mental) health related quality of life (QoL) on the other, in Maastricht, the Netherlands...
  95. ncbi request reprint When does experience of psychosis result in a need for care? A prospective general population study
    Maarten Bak
    Department of Psychiatry and Neuropsychology, azM Mondriaan RIBW Riagg Vijverdal Academic Centre, EURON, Maastricht University, The Netherlands
    Schizophr Bull 29:349-58. 2003
    ....
  96. ncbi request reprint Social needs in daily life in adults with Pervasive Developmental Disorders
    Anouk Hintzen
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, P O Box 616, 6200 MD, Maastricht University Medical Centre, The Netherlands
    Psychiatry Res 179:75-80. 2010
    ..Therapeutic interventions should aim at decreasing negative affect and anxiety in social interactions possibly by improving social skills to fulfil the existing social needs in adults with PDD...
  97. pmc Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: an 8-year cohort study
    M D G Dominguez
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, PO BOX 616 DRT 10, 6200 MD Maastricht, The Netherlands
    Schizophr Bull 37:84-93. 2011
    ..This may be summarized descriptively as a psychosis proneness-persistence-impairment model of psychotic disorder...
  98. ncbi request reprint Searching for a structural endophenotype in psychosis using computational morphometry
    Machteld Marcelis
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Psychiatry Res 122:153-67. 2003
    ..Patients with psychosis and first-degree healthy relatives of patients with psychosis show cerebellar abnormalities, which may constitute a marker of genetic transmission...
  99. ncbi request reprint Instability in self-esteem and paranoia in a general population sample
    Viviane Thewissen
    Dept of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, P O Box 616 DRT 10, 6200, MD, Mastricht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 42:1-5. 2007
    ..A plausible explanation for these inconsistencies is that self-esteem is unstable in paranoid individuals...
  100. ncbi request reprint Associations between COMTVal158Met polymorphism and cognition: direct or indirect effects?
    Lydia Krabbendam
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, PO BOX 616 VIJV, 6200 MD Maastricht, The Netherlands
    Eur Psychiatry 21:338-42. 2006
    ..This study examined (i) to what degree RTV pertaining to tasks of varying cognitive complexity would be associated with increased risk for schizophrenia and (ii) to what degree this would be mediated by Val loading...
  101. doi request reprint Genetic moderation of CO2-induced fear by 5-HTTLPR genotype
    Koen Schruers
    Academic Anxiety Center, Maastricht University, Maastricht, The Netherlands
    J Psychopharmacol 25:37-42. 2011
    ..These results are in line with current theories on the role of 5-HT in both panic and respiration...