Freddy J Troost

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint Gastric digestion of bovine lactoferrin in vivo in adults
    F J Troost
    Department of Human Biology, Nutrition and Toxicology Institute Maastricht, Universiteitssingel, Maastricht, The Netherlands
    J Nutr 131:2101-4. 2001
  2. ncbi request reprint Orally ingested human lactoferrin is digested and secreted in the upper gastrointestinal tract in vivo in women with ileostomies
    Freddy J Troost
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht, The Netherlands
    J Nutr 132:2597-600. 2002
  3. ncbi request reprint New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application
    Freddy J Troost
    Dept of Human Biology, Research Institute Maastricht, MaastrichtUniversity, The Netherlands
    Am J Physiol Gastrointest Liver Physiol 285:G354-9. 2003
  4. ncbi request reprint Iron supplements inhibit zinc but not copper absorption in vivo in ileostomy subjects
    Freddy J Troost
    Department of Human Biology, NUTRIM, Maastricht University, Maastricht, Netherlands
    Am J Clin Nutr 78:1018-23. 2003
  5. ncbi request reprint Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers
    F J Troost
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Eur J Clin Nutr 57:1579-85. 2003
  6. ncbi request reprint Local effect of adenosine 5'-triphosphate on indomethacin-induced permeability changes in the human small intestine
    Martijn J Bours
    Department of Epidemiology, Maastricht University, Nutrition and Toxicology Research Institute Maastricht, Maastricht, The Netherlands
    Eur J Gastroenterol Hepatol 19:245-50. 2007
  7. doi request reprint Validation of Ussing chamber technology to study satiety hormone release from human duodenal specimens
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Obesity (Silver Spring) 20:678-82. 2012
  8. ncbi request reprint Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress
    Freddy J Troost
    Department of Internal Medicine Gastroenterology, Maastricht University, Maastricht, The Netherlands
    Physiol Genomics 25:242-9. 2006
  9. doi request reprint Addition of sucralose enhances the release of satiety hormones in combination with pea protein
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Mol Nutr Food Res 56:417-24. 2012
  10. pmc Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese male subjects
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 6:e24878. 2011

Detail Information

Publications16

  1. ncbi request reprint Gastric digestion of bovine lactoferrin in vivo in adults
    F J Troost
    Department of Human Biology, Nutrition and Toxicology Institute Maastricht, Universiteitssingel, Maastricht, The Netherlands
    J Nutr 131:2101-4. 2001
    ..However, it did not elevate intragastric pH over a prolonged period and thereby inhibit intragastric LF breakdown. We conclude that after oral administration, substantial amounts of apoLF and holoLF survive gastric transit...
  2. ncbi request reprint Orally ingested human lactoferrin is digested and secreted in the upper gastrointestinal tract in vivo in women with ileostomies
    Freddy J Troost
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht, The Netherlands
    J Nutr 132:2597-600. 2002
    ..Hence, dietary rhLF is digested in the upper GI tract and does not reach the colon. Intact LF appearing in ileostomy effluent is likely to originate from an endogenous source...
  3. ncbi request reprint New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application
    Freddy J Troost
    Dept of Human Biology, Research Institute Maastricht, MaastrichtUniversity, The Netherlands
    Am J Physiol Gastrointest Liver Physiol 285:G354-9. 2003
    ..05). These data show that a single dosage of ferrous sulfate induces oxidative damage and the subsequent release of an antioxidant in the small intestine in vivo in healthy volunteers...
  4. ncbi request reprint Iron supplements inhibit zinc but not copper absorption in vivo in ileostomy subjects
    Freddy J Troost
    Department of Human Biology, NUTRIM, Maastricht University, Maastricht, Netherlands
    Am J Clin Nutr 78:1018-23. 2003
    ..Iron supplements may inhibit intestinal zinc and copper uptake because these elements may compete for binding to a transporter molecule (divalent metal transporter 1) that is located on the apical side of the small intestinal epithelium...
  5. ncbi request reprint Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers
    F J Troost
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Eur J Clin Nutr 57:1579-85. 2003
    ....
  6. ncbi request reprint Local effect of adenosine 5'-triphosphate on indomethacin-induced permeability changes in the human small intestine
    Martijn J Bours
    Department of Epidemiology, Maastricht University, Nutrition and Toxicology Research Institute Maastricht, Maastricht, The Netherlands
    Eur J Gastroenterol Hepatol 19:245-50. 2007
    ....
  7. doi request reprint Validation of Ussing chamber technology to study satiety hormone release from human duodenal specimens
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Obesity (Silver Spring) 20:678-82. 2012
    ....
  8. ncbi request reprint Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress
    Freddy J Troost
    Department of Internal Medicine Gastroenterology, Maastricht University, Maastricht, The Netherlands
    Physiol Genomics 25:242-9. 2006
    ....
  9. doi request reprint Addition of sucralose enhances the release of satiety hormones in combination with pea protein
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Mol Nutr Food Res 56:417-24. 2012
    ..There are indications that each sweetener has different effects on this release, and that combining sweeteners with other nutrients might exert synergistic effects on hormone release...
  10. pmc Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese male subjects
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 6:e24878. 2011
    ..This study investigated whether bypassing the stomach, through intraduodenal administration, affects hormone release and food-intake to a larger extent than orally administered protein in both lean and obese subjects...
  11. ncbi request reprint Intestinal absorption of different types of folate in healthy subjects with an ileostomy
    Erik J M Konings
    Nutrition and Toxicology Research Institute NUTRIM, Maastricht University, The Netherlands
    Br J Nutr 88:235-42. 2002
    ..We conclude that the deconjugation process is not a limiting factor in the absorption of spinach folates. Comparison of AUC of food folate v. folic acid in a short-term protocol may be suitable for assessing food folate bioavailability...
  12. pmc Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo
    Freddy J Troost
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University, Maastricht, The Netherlands
    BMC Genomics 9:374. 2008
    ..plantarum WCFS1 for one- and six h, respectively, were studied using oro- and nasogastric intubations with dedicated orogastric catheters and tissue sampling by standard flexible gastroduodenoscopy...
  13. doi request reprint Release of satiety hormones in response to specific dietary proteins is different between human and murine small intestinal mucosa
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Centre, Maastricht, The Netherlands M Geraedts HB unimaas nl
    Ann Nutr Metab 56:308-13. 2010
    ..Here, the effects of specific dietary proteins on intestinal CCK and GLP-1 release were examined...
  14. doi request reprint Direct induction of CCK and GLP-1 release from murine endocrine cells by intact dietary proteins
    Maartje C P Geraedts
    Department of Human Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
    Mol Nutr Food Res 55:476-84. 2011
    ..This study investigated which dietary proteins, hydrolysates, or synthetic-peptides are most potent to affect secretion of CCK and GLP-1 in STC-1 cells known for satiety hormone release...
  15. doi request reprint Butyrate modulates oxidative stress in the colonic mucosa of healthy humans
    Henrike M Hamer
    TI Food and Nutrition, Wageningen, The Netherlands
    Clin Nutr 28:88-93. 2009
    ..This study evaluates whether butyrate plays a role in oxidative stress in the healthy colonic mucosa...
  16. pmc Butyrate-induced transcriptional changes in human colonic mucosa
    Steven A L W Vanhoutvin
    TI Food and Nutrition, Wageningen, The Netherlands
    PLoS ONE 4:e6759. 2009
    ..Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown. This study aimed to determine the effects of butyrate on the transcriptional regulation of human colonic mucosa in vivo...