B Schutte

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics
    B Schutte
    Department of Molecular Cell Biology and Genetics, University of Maastricht, The Netherlands
    Exp Cell Res 236:4-15. 1997
  2. ncbi The caspase-9 derived C-terminal fragment of cytokeratin 18 modulates topoisomerase action
    B Schutte
    Department of Molecular Cell Biology, University of Maastricht, Maastricht, The Netherlands
    Int J Oncol 35:625-30. 2009
  3. ncbi DEDD association with cytokeratin filaments correlates with sensitivity to apoptosis
    Bert Schutte
    Department of Molecular Cell Biology, Research Institute Growth and Development, GROW, University of Maastricht, P O Box 616, 6200, MD, Maastricht, The Netherlands
    Apoptosis 11:1561-72. 2006
  4. ncbi Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells
    B Schutte
    Department of Molecular Cell Biology and Genetics, University of Maastricht, The Netherlands
    J Neurosci Methods 86:63-9. 1998
  5. ncbi Keratin 8/18 breakdown and reorganization during apoptosis
    Bert Schutte
    Department of Molecular Cell Biology Box 17, Research Institute Growth and Development GROW, University of Maastricht, The Netherlands
    Exp Cell Res 297:11-26. 2004
  6. ncbi Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis
    M E R Henfling
    Department of Molecular Cell Biology, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Int J Oncol 25:1437-46. 2004
  7. ncbi Low concentrations of ethanol induce apoptosis in human intestinal cells
    K Asai
    Dept. of Surgery, University of Maastricht, The Netherlands
    Scand J Gastroenterol 38:1154-61. 2003
  8. ncbi S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules
    D Terwel
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience EURON, Maastricht University, P O Box 616, 6200 MD, Maastricht, Netherlands
    Eur J Pharmacol 400:19-33. 2000
  9. ncbi Inhibition of the cell cycle and induction of apoptosis by Noclosan and Loxat in cell lines irrespective of their origin
    B Schutte
    Department of Molecular Cell Biology, Research Institute for Growth and Development (GROW, University of Maastricht, Maastricht, The Netherlands
    Int J Oncol 24:1357-67. 2004
  10. ncbi Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation
    S M van den Eijnde
    Department of Molecular Cell Biology, Cardiovascular Research Institute Maastricht, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    J Cell Sci 114:3631-42. 2001

Collaborators

Detail Information

Publications15

  1. ncbi The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics
    B Schutte
    Department of Molecular Cell Biology and Genetics, University of Maastricht, The Netherlands
    Exp Cell Res 236:4-15. 1997
    ..The presented data suggest that cyclins and CDKs are involved at an important nodal point shared by pathways regulating cellular proliferation and apoptosis...
  2. ncbi The caspase-9 derived C-terminal fragment of cytokeratin 18 modulates topoisomerase action
    B Schutte
    Department of Molecular Cell Biology, University of Maastricht, Maastricht, The Netherlands
    Int J Oncol 35:625-30. 2009
    ..This leads to preservation of general transcriptional activity required to exert active steps during early stages of programmed cell death...
  3. ncbi DEDD association with cytokeratin filaments correlates with sensitivity to apoptosis
    Bert Schutte
    Department of Molecular Cell Biology, Research Institute Growth and Development, GROW, University of Maastricht, P O Box 616, 6200, MD, Maastricht, The Netherlands
    Apoptosis 11:1561-72. 2006
    ..Our data support the notion that DEDD-mediated accumulation of procaspases at the cytokeratin scaffold leads to an increase in the local concentration, which renders cells more apoptosis-prone...
  4. ncbi Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells
    B Schutte
    Department of Molecular Cell Biology and Genetics, University of Maastricht, The Netherlands
    J Neurosci Methods 86:63-9. 1998
    ..In the present paper, we show that the annexin V-binding assay is also applicable to differentiated neuronal cells with fragile neurite outgrowths...
  5. ncbi Keratin 8/18 breakdown and reorganization during apoptosis
    Bert Schutte
    Department of Molecular Cell Biology Box 17, Research Institute Growth and Development GROW, University of Maastricht, The Netherlands
    Exp Cell Res 297:11-26. 2004
    ..At later stages of the apoptotic process, that is, when the integrity of the cytoplasmic membrane becomes compromised, keratin aggregates are shed from the cells...
  6. ncbi Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis
    M E R Henfling
    Department of Molecular Cell Biology, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Int J Oncol 25:1437-46. 2004
    ..Taken together our data suggest a specific role for proteasomes very early in roscovitine-induced apoptosis, upstream from the caspase cascade and mitochondrion...
  7. ncbi Low concentrations of ethanol induce apoptosis in human intestinal cells
    K Asai
    Dept. of Surgery, University of Maastricht, The Netherlands
    Scand J Gastroenterol 38:1154-61. 2003
    ..This impairment of the barrier function would allow endotoxin to enter the circulation and evoke hepatic inflammation...
  8. ncbi S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules
    D Terwel
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience EURON, Maastricht University, P O Box 616, 6200 MD, Maastricht, Netherlands
    Eur J Pharmacol 400:19-33. 2000
    ....
  9. ncbi Inhibition of the cell cycle and induction of apoptosis by Noclosan and Loxat in cell lines irrespective of their origin
    B Schutte
    Department of Molecular Cell Biology, Research Institute for Growth and Development (GROW, University of Maastricht, Maastricht, The Netherlands
    Int J Oncol 24:1357-67. 2004
    ..Preliminary studies suggest that the components affect the SAPK/JNK cell signaling pathway...
  10. ncbi Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation
    S M van den Eijnde
    Department of Molecular Cell Biology, Cardiovascular Research Institute Maastricht, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    J Cell Sci 114:3631-42. 2001
    ..Our findings indicate that different mechanisms regulate PS exposure during apoptosis and muscle cell differentiation, and that surface exposed PS plays a crucial role in the process of myotube formation...
  11. ncbi Effect of tissue fixation on anti-bromodeoxyuridine immunohistochemistry
    B Schutte
    Department of Internal Medicine, University of Limburg, Maastricht, The Netherlands
    J Histochem Cytochem 35:1343-5. 1987
    ..The optimal pepsin concentration was determined for maximal immunoreactivity combined with acceptable morphology...
  12. ncbi Role of differential cell proliferation in the tail bud in aberrant mouse neurulation
    M C Peeters
    Department of Anatomy and Embryology, University of Maastricht, The Netherlands
    Dev Dyn 211:382-9. 1998
    ....
  13. ncbi Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis
    Jos L V Broers
    Department of Molecular Cell Biology, Research Institute Growth and Development GROW, University of Maastricht, Maastricht, The Netherlands
    Eur J Cell Biol 81:677-91. 2002
    ....
  14. ncbi Modular effects of estradiol on ethanol-induced apoptosis in human intestinal epithelial cells
    Kiyoko Asai
    Department of Surgery, University of Maastricht, The Netherlands
    Scand J Gastroenterol 40:326-35. 2005
    ..The aim of this study was to examine the influence of estradiol on the intestinal cell death induced by acute and low concentrations of ethanol in an in vitro system...
  15. ncbi Dual roles of intermediate filaments in apoptosis
    Normand Marceau
    Centre de recherche en cancérologie de l Université Laval and L Hôtel Dieu de Québec CHUQ, Quebec, Canada G1R 2J6
    Exp Cell Res 313:2265-81. 2007
    ..Clearly, the data accumulated in recent years provide new and significant insights into the multiple functions of IFs, particularly their dual roles in cell response to apoptotic insults...