Leo J Schouten

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. pmc Reproductive and hormonal factors in association with ovarian cancer in the Netherlands cohort study
    M G M Braem
    University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 172:1181-9. 2010
  2. pmc Energy restriction during childhood and early adulthood and ovarian cancer risk
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e27960. 2011
  3. pmc Alcohol consumption, cigarette smoking, and endometrial cancer risk: results from the Netherlands Cohort Study
    Adrian Loerbroks
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Cancer Causes Control 18:551-60. 2007
  4. pmc Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study
    Kjeld P van Houwelingen
    Department of Urology, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    BMC Cancer 5:57. 2005
  5. ncbi request reprint Anthropometry, physical activity, and endometrial cancer risk: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, Nutrition and Toxicology Research Institute, P O Box 616, 6200 MD Maastricht, The Netherlands
    J Natl Cancer Inst 96:1635-8. 2004
  6. doi request reprint Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 17:3543-50. 2008
  7. ncbi request reprint Anthropometry, physical activity, and endometrial cancer risk: results from the Netherlands cohort study
    L J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, MD Maastricht, The Netherlands
    Int J Gynecol Cancer 16:492. 2006
  8. ncbi request reprint Alcohol and ovarian cancer risk: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Causes Control 15:201-9. 2004
  9. ncbi request reprint Height, weight, weight change, and ovarian cancer risk in the Netherlands cohort study on diet and cancer
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 157:424-33. 2003
  10. doi request reprint Dietary acrylamide intake and the risk of head-neck and thyroid cancers: results from the Netherlands Cohort Study
    Leo J Schouten
    GROW, School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 170:873-84. 2009

Detail Information

Publications78

  1. pmc Reproductive and hormonal factors in association with ovarian cancer in the Netherlands cohort study
    M G M Braem
    University Medical Center Utrecht, The Netherlands
    Am J Epidemiol 172:1181-9. 2010
    ..Moreover, no associations were observed for age at first birth, age at menarche, age at first and last use of oral contraceptives, and use of hormone replacement therapy...
  2. pmc Energy restriction during childhood and early adulthood and ovarian cancer risk
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e27960. 2011
    ..Our results show a relation between proxy variables for modest energy restriction over a longer period of time during childhood or early adulthood and a reduced ovarian cancer risk...
  3. pmc Alcohol consumption, cigarette smoking, and endometrial cancer risk: results from the Netherlands Cohort Study
    Adrian Loerbroks
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Cancer Causes Control 18:551-60. 2007
    ..To examine the association between alcohol consumption, cigarette smoking, and endometrial cancer...
  4. pmc Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study
    Kjeld P van Houwelingen
    Department of Urology, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    BMC Cancer 5:57. 2005
    ..We studied the VHL mutation status in a large population-based case group...
  5. ncbi request reprint Anthropometry, physical activity, and endometrial cancer risk: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, Nutrition and Toxicology Research Institute, P O Box 616, 6200 MD Maastricht, The Netherlands
    J Natl Cancer Inst 96:1635-8. 2004
    ..54, 95% CI = 0.34 to 0.85; P(trend) = .002) compared with those who spent less than 30 minutes per day. High BMI and low physical activity were strong and independent risk factors for endometrial cancer...
  6. doi request reprint Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 17:3543-50. 2008
    ..58; 95% CI, 0.34-0.99). In this study, a not statistically significant inverse association was observed between alcohol and renal cell cancer. There was no statistical significant heterogeneity by VHL mutation or methylation status...
  7. ncbi request reprint Anthropometry, physical activity, and endometrial cancer risk: results from the Netherlands cohort study
    L J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, MD Maastricht, The Netherlands
    Int J Gynecol Cancer 16:492. 2006
  8. ncbi request reprint Alcohol and ovarian cancer risk: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Causes Control 15:201-9. 2004
    ..To study alcohol consumption in relation to ovarian cancer risk in a prospective cohort study...
  9. ncbi request reprint Height, weight, weight change, and ovarian cancer risk in the Netherlands cohort study on diet and cancer
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 157:424-33. 2003
    ..These data support a positive association between height (and to a lesser extent body mass) and ovarian cancer risk in this population of postmenopausal women...
  10. doi request reprint Dietary acrylamide intake and the risk of head-neck and thyroid cancers: results from the Netherlands Cohort Study
    Leo J Schouten
    GROW, School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 170:873-84. 2009
    ..Dietary acrylamide intake was not positively associated with risk of head-neck and thyroid cancer, except with oral cavity cancer risk for female nonsmokers. A negative association for males was indicated...
  11. ncbi request reprint Rising incidence of breast cancer after completion of the first prevalent round of the breast cancer screening programme
    L J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    J Med Screen 9:120-4. 2002
    ..This increase was contrary to expectations, which had predicted a slightly higher, but stable, incidence after the first screening round. The trends in incidence were studied to find explanations for the observed rise in incidence...
  12. ncbi request reprint Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
    Leo J Schouten
    Department of Epidemiology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cancer 94:2698-705. 2002
    ....
  13. pmc Height, body mass index, and ovarian cancer: a pooled analysis of 12 cohort studies
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 17:902-12. 2008
    ..Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent...
  14. doi request reprint Lung cancer risk in relation to dietary acrylamide intake
    Janneke G F Hogervorst
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, PO Box 616, 6200 Maastricht, The Netherlands
    J Natl Cancer Inst 101:651-62. 2009
    ..The association between dietary acrylamide intake and lung cancer risk is not known...
  15. doi request reprint Risk prediction of incident coronary heart disease in The Netherlands: re-estimation and improvement of the SCORE risk function
    Audrey H H Merry
    Department of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands
    Eur J Prev Cardiol 19:840-8. 2012
    ....
  16. ncbi request reprint Carotenoid and vitamin intake, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma
    Boukje A C van Dijk
    Department of Epidemiology, NUTRIM, Maastricht University, Maastricht, The Netherlands
    Cancer Causes Control 19:125-34. 2008
    ..We investigated whether dietary carotenoid and vitamin intake and supplemental vitamin use were inversely associated with RCC risk and with Von Hippel-Lindau (VHL)-gene mutations in clear-cell renal cell carcinoma (RCC)...
  17. doi request reprint Dietary acrylamide intake and estrogen and progesterone receptor-defined postmenopausal breast cancer risk
    Grete S Pedersen
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Breast Cancer Res Treat 122:199-210. 2010
    ..Further studies are needed to confirm or refute our observations...
  18. ncbi request reprint Dietary acrylamide intake and the risk of renal cell, bladder, and prostate cancer
    Janneke G Hogervorst
    Department of Epidemiology, School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Am J Clin Nutr 87:1428-38. 2008
    ..Acrylamide, a probable human carcinogen, was recently detected in various heat-treated carbohydrate-rich foods. Epidemiologic studies on the relation with cancer have been few and largely negative...
  19. doi request reprint Body mass index and von Hippel-Lindau gene mutations in clear-cell renal cancer: Results of the Netherlands Cohort Study on diet and cancer
    Kim M Smits
    Department of Epidemiology, Maastricht University, The Netherlands
    Ann Epidemiol 20:401-4. 2010
    ..We evaluated the association between BMI and VHL mutations in cc-RCC by using data from the Netherlands Cohort Study (NLCS), a prospective study, which comprises 120,852 persons...
  20. ncbi request reprint Hypertension, antihypertensives and mutations in the Von Hippel-Lindau gene in renal cell carcinoma: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, The Netherlands
    J Hypertens 23:1997-2004. 2005
    ..Hypertension and/or antihypertensive medication are reported to be risk factors of renal cell carcinoma (RCC). We investigated whether these risk factors are associated with von Hippel-Lindau gene (VHL) mutations in RCC...
  21. doi request reprint Co-occurrence of metabolic factors and the risk of coronary heart disease: a prospective cohort study in the Netherlands
    Audrey H H Merry
    Department of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands
    Int J Cardiol 155:223-9. 2012
    ....
  22. doi request reprint The carcinogenicity of dietary acrylamide intake: a comparative discussion of epidemiological and experimental animal research
    Janneke G F Hogervorst
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Crit Rev Toxicol 40:485-512. 2010
    ..The observed pattern of increased risks in the rat and epidemiological studies and the decreased risks in the epidemiological studies suggests that acrylamide might influence hormonal systems, for which rodents may not be good models...
  23. doi request reprint Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis
    Kim M Smits
    Departmens of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Clin Cancer Res 14:782-7. 2008
    ..We have evaluated the influence of (epi)genetic alterations in VHL on cause-specific survival in clear-cell renal cell cancer (ccRCC) in a large, population-based group of cases...
  24. doi request reprint Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer
    Stefan de Vogel
    Department of Epidemiology, GROW, School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Carcinogenesis 29:1765-73. 2008
    ....
  25. doi request reprint A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer
    Kim M Smits
    Departments of Pathology and Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
    Clin Cancer Res 17:7723-31. 2011
    ..Effects in early-stage CRC are however unknown. We studied KRAS-LCS6 genotype, hypothesizing that it might identify early-stage cases with a poor prognosis, and could potentially be used in therapy decision-making...
  26. doi request reprint Dietary acrylamide intake and brain cancer risk
    Janneke G F Hogervorst
    Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 18:1663-6. 2009
    ..In the current study, the association between dietary acrylamide intake and human brain cancer risk was investigated for the first time...
  27. doi request reprint Selenium status and the risk of esophageal and gastric cancer subtypes: the Netherlands cohort study
    Jessie Steevens
    GROW School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University Medical Centre, Maastricht, The Netherlands
    Gastroenterology 138:1704-13. 2010
    ..Only in very few studies have the associations with ESCC and GCA been investigated, and no epidemiologic studies exist on EAC...
  28. ncbi request reprint A prospective study of dietary acrylamide intake and the risk of endometrial, ovarian, and breast cancer
    Janneke G Hogervorst
    Department of Epidemiology, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 16:2304-13. 2007
    ..The few epidemiologic studies done thus far have not shown a relationship with cancer. Our aim was to investigate the association between acrylamide intake and endometrial, ovarian, and breast cancer risk...
  29. doi request reprint Total cancer incidence and overall mortality are not increased among patients with Barrett's esophagus
    Leo J Schouten
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
    Clin Gastroenterol Hepatol 9:754-61. 2011
    ..Barrett's esophagus (BE) increases risk for esophageal adenocarcinoma, but it is not clear how it affects risk for other cancers or overall mortality. We analyzed data from a population-based cohort of subjects with BE...
  30. ncbi request reprint Polymorphisms in genes related to activation or detoxification of carcinogens might interact with smoking to increase renal cancer risk: results from The Netherlands Cohort Study on diet and cancer
    Kim M Smits
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    World J Urol 26:103-10. 2008
    ..This could indicate that RCC risk among smokers might be more increased with the CYP1A1*2C genotype, GSTmicro1 null, or both a CYP1A1 variant and GSTmicro1 null...
  31. ncbi request reprint Relation of height, body mass, energy intake, and physical activity to risk of renal cell carcinoma: results from the Netherlands Cohort Study
    Boukje A C van Dijk
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Epidemiol 160:1159-67. 2004
    ..These results suggest that body mass index and gain in body mass index since age 20 are associated with increased risk of RCC...
  32. doi request reprint A prospective cohort study on overweight, smoking, alcohol consumption, and risk of Barrett's esophagus
    Jessie Steevens
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 20:345-58. 2011
    ..Besides gastroesophageal reflux, possible risk factors for BE include overweight, cigarette smoking, and alcohol consumption. Our objective was to study these associations by using prospective data...
  33. doi request reprint Dietary acrylamide intake is not associated with gastrointestinal cancer risk
    Janneke G F Hogervorst
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht 6200 MD, The Netherlands
    J Nutr 138:2229-36. 2008
    ..Overall, acrylamide intake was not associated with colorectal, gastric, pancreatic, and esophageal cancer risk, but some subgroups deserve further attention...
  34. pmc Smoking, alcohol consumption, physical activity, and family history and the risks of acute myocardial infarction and unstable angina pectoris: a prospective cohort study
    Audrey H H Merry
    Department of Epidemiology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands
    BMC Cardiovasc Disord 11:13. 2011
    ..Additionally, we investigated whether these effects differed between subjects with and without a family history of myocardial infarction (MI)...
  35. doi request reprint Vegetables and fruits consumption and risk of esophageal and gastric cancer subtypes in the Netherlands Cohort Study
    Jessie Steevens
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands
    Int J Cancer 129:2681-93. 2011
    ..Consumption of (specific groups of) vegetables and fruits may protect against subtypes of esophageal and gastric cancer...
  36. ncbi request reprint Vegetable and fruit consumption and risk of renal cell carcinoma: results from the Netherlands cohort study
    Boukje A C van Dijk
    Department of Epidemiology, NUTRIM, Maastricht University, The Netherlands
    Int J Cancer 117:648-54. 2005
    ..76; 95% CI 1.28-2.42), which must be regarded cautiously because of multiple testing. These results suggest the absence of an association between vegetable and/or fruit consumption and RCC risk...
  37. ncbi request reprint Consumption of vegetables and fruits and risk of ovarian carcinoma
    Monique Mommers
    Department of Epidemiology, NUTRIM, Maastricht University, Maastricht, The Netherlands
    Cancer 104:1512-9. 2005
    ..To the authors' knowledge, only a few prospective studies to date have investigated the correlation between vegetable and fruit consumption and the risk of ovarian carcinoma and their results have been inconclusive...
  38. doi request reprint Meat consumption and the risk of Barrett's esophagus in a large Dutch cohort
    Andras P Keszei
    Departments of Epidemiology and Pathology, School for Oncology and Developmental Biology GROW, Maastricht University, Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 22:1162-6. 2013
    ..Increasing meat intake and its possible role in the development of esophageal adenocarcinoma raises the question whether meat consumption is associated with the premalignant lesion, Barrett's esophagus...
  39. doi request reprint Dietary N-nitroso compounds, endogenous nitrosation, and the risk of esophageal and gastric cancer subtypes in the Netherlands Cohort Study
    Andras P Keszei
    School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University, Maastricht, Netherlands
    Am J Clin Nutr 97:135-46. 2013
    ..Dietary N-nitroso compounds and endogenous nitrosation are important carcinogenic factors, but human evidence of their role is scarce for esophageal cancer and inconsistent for gastric cancer...
  40. doi request reprint Dairy intake and the risk of bladder cancer in the Netherlands Cohort Study on Diet and Cancer
    Andras P Keszei
    Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 171:436-46. 2010
    ..These results provide weak evidence that bladder cancer risk is inversely associated with low intake of fermented dairy products and suggest a positive association with butter intake in women...
  41. doi request reprint Bowel movement and constipation frequencies and the risk of colorectal cancer among men in the Netherlands Cohort Study on Diet and Cancer
    Colinda C J M Simons
    Department of Epidemiology, Faculty of Health, Medicine and Life Sciences, MaastrichtUniversity, P O Box 616, 6200 MD Maastricht, The Netherlands
    Am J Epidemiol 172:1404-14. 2010
    ..Interactions with dietary fiber intake were not significant. In this study, frequent bowel movements were associated with an increased risk of rectal cancer in men, and constipation was associated with a decreased risk...
  42. doi request reprint Longitudinal changes in BMI in older adults are associated with meat consumption differentially, by type of meat consumed
    Anne M J Gilsing
    Department of Epidemiology, School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands
    J Nutr 142:340-9. 2012
    ..However, total meat consumption, or factors directly related to total meat intake, was not strongly associated with weight change during the 14-y prospective follow-up in this elderly population...
  43. doi request reprint Total fluid and specific beverage intake and mortality due to IHD and stroke in the Netherlands Cohort Study
    Lina J Leurs
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Br J Nutr 104:1212-21. 2010
    ..Coffee consumption was inversely associated with IHD mortality in women only, while a higher tea intake was associated with lower IHD mortality in men only...
  44. pmc Toenail selenium status and the risk of Barrett's esophagus: the Netherlands Cohort Study
    Jessie Steevens
    GROW School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University Medical Centre, PO Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Causes Control 21:2259-68. 2010
    ..To investigate the association between selenium and the risk of Barrett's esophagus (BE), the precursor lesion of esophageal adenocarcinoma...
  45. doi request reprint Body mass index, height, and risk of lymphatic malignancies: a prospective cohort study
    Romana D Pylypchuk
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Am J Epidemiol 170:297-307. 2009
    ..The positive associations among BMI at 20 years of age, height, and the risk of lymphatic malignancies suggest that exposures during early life play a role in the etiology of lymphatic malignancies...
  46. doi request reprint Trends in incidence of oesophageal and stomach cancer subtypes in Europe
    Jessie Steevens
    GROW School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Eur J Gastroenterol Hepatol 22:669-78. 2010
    ..The main goal of this study was to investigate more recent trends in the incidence of oesophageal and stomach cancer subtypes in the European countries...
  47. pmc Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma
    Iris J H van Vlodrop
    Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Pathol 176:575-84. 2010
    ..59, respectively). The strong correlation between GREM1 region iii promoter methylation and increased malignancy and its correlation with active angiogenesis indicates a role for GREM1 in ccRCC carcinogenesis and tumor angiogenesis...
  48. ncbi request reprint Physical activity and risk of ovarian cancer: results from the Netherlands Cohort Study (The Netherlands)
    Regien G Biesma
    Department of Epidemiology, NUTRIM, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Cancer Causes Control 17:109-15. 2006
    ..To investigate the association between nonoccupational physical activity and the risk of ovarian cancer among post-menopausal women...
  49. doi request reprint Alcohol consumption and risk of lymphoid and myeloid neoplasms: results of the Netherlands cohort study
    Mirjam M Heinen
    School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University Medical Center, Maastricht, The Netherlands
    Int J Cancer 133:1701-12. 2013
    ..Also, no inverse association was observed with myeloid neoplasms. If any association between alcohol consumption and lymphoid neoplasms exists, our study suggests an increased risk rather than a decreased risk. ..
  50. pmc Dietary acrylamide intake and the risk of lymphatic malignancies: the Netherlands Cohort Study on diet and cancer
    Mathilda L Bongers
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University Medical Centre, Maastricht, The Netherlands
    PLoS ONE 7:e38016. 2012
    ..The aim of this prospective study is to investigate for the first time the association between dietary acrylamide intake and the risk of several histological subtypes of lymphatic malignancies...
  51. doi request reprint Fluid intake and colorectal cancer risk in the Netherlands Cohort Study
    Colinda C J M Simons
    GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Nutr Cancer 62:307-21. 2010
    ..There was no evidence that fiber intake modified associations. Of the specific beverages, coffee intake was positively associated with rectal cancer risk in men...
  52. doi request reprint Self-reported clothing size as a proxy measure for body size
    Laura A E Hughes
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University, Maastricht, The Netherlands
    Epidemiology 20:673-6. 2009
    ..Few studies have considered the potential utility of clothing size as a predictor of diseases associated with body weight...
  53. ncbi request reprint Anthropometry and pancreatic cancer risk: an illustration of the importance of microscopic verification
    Bas A J Verhage
    Department of Epidemiology Nutrition and Toxicology Research Institute Maastricht, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cancer Epidemiol Biomarkers Prev 16:1449-54. 2007
    ..If MCPC and NMCPC had been considered as one group, the reported associations would not have been detected. These findings stress the need to evaluate heterogeneity among pancreatic cancer cases in etiologic studies...
  54. doi request reprint Dietary folate and folate vitamers and the risk of prostate cancer in The Netherlands Cohort Study
    Bas A J Verhage
    Department of Epidemiology, School for Oncology and Developmental Biology GROW, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    Cancer Causes Control 23:2003-11. 2012
    ..The aim of the present study was to examine the association between intake of folate, and specific folate vitamers, and the risk of advanced and total prostate cancer...
  55. doi request reprint Validity of coronary heart diseases and heart failure based on hospital discharge and mortality data in the Netherlands using the cardiovascular registry Maastricht cohort study
    Audrey H H Merry
    Department of Epidemiology, School for Public Health and Primary Care CAPHRI, Maastricht University, Maastricht, The Netherlands
    Eur J Epidemiol 24:237-47. 2009
    ..Incidence rates based on hospital discharge and mortality data may underestimate the true incidence rates, especially for unstable angina pectoris and heart failure...
  56. pmc Body mass index, height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study
    Audrey H H Merry
    Department of Epidemiology, NUTRIM, Maastricht University, PO Box 616, 6200 MD, Maastricht, Netherlands
    Gut 56:1503-11. 2007
    ..We investigated the association between body mass index (BMI), height and risk of oesophageal and gastric cardia adenocarcinoma...
  57. doi request reprint Genetics and epigenetics of renal cell cancer
    Marcella M L Baldewijns
    Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Biochim Biophys Acta 1785:133-55. 2008
    ..In this review we discuss the background of RCC and the clinical applications of RCC genetics and epigenetics...
  58. ncbi request reprint Fat and K-ras mutations in sporadic colorectal cancer in The Netherlands Cohort Study
    Mirian Brink
    Nutrition and Toxicology Research Institute Maastricht, Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Carcinogenesis 25:1619-28. 2004
    ..A high intake of polyunsaturated fat, in particular linoleic acid, may be an important dietary risk factor for K-ras mutated colon tumours, possibly by generating G > A transitions or G > T or G > C transversions in the K-ras oncogene...
  59. doi request reprint Consumption of dietary fat and meat and risk of ovarian cancer in the Netherlands Cohort Study
    Anne M J Gilsing
    Department of Epidemiology, School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
    Am J Clin Nutr 93:118-26. 2011
    ..Evidence that links dietary factors to ovarian cancer is conflicting, but several epidemiologic studies suggested that consumption of dietary fat and meat may increase risk of ovarian cancer...
  60. doi request reprint The Netherlands Cohort Study-Meat Investigation Cohort; a population-based cohort over-represented with vegetarians, pescetarians and low meat consumers
    Anne Mj Gilsing
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, PO Box 616, Maastricht 6216, MD, The Netherlands
    Nutr J 12:156. 2013
    ..In addition, we were able to compare self-reported vegetarians with vegetarians whose status has been confirmed by their response on the extensive food frequency questionnaire (FFQ)...
  61. pmc Relationship between tap water hardness, magnesium, and calcium concentration and mortality due to ischemic heart disease or stroke in The Netherlands
    Lina J Leurs
    Maastricht University, GROW School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht, The Netherlands
    Environ Health Perspect 118:414-20. 2010
    ..Conflicting results on the relationship between the hardness of drinking water and mortality related to ischemic heart disease (IHD) or stroke have been reported...
  62. ncbi request reprint Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries
    A A Botterweck
    Maastricht University, Department of Epidemiology, Maastricht, The Netherlands
    Int J Epidemiol 29:645-54. 2000
    ....
  63. pmc Tea and coffee drinking and ovarian cancer risk: results from the Netherlands Cohort Study and a meta-analysis
    J Steevens
    Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Br J Cancer 97:1291-4. 2007
    ..89, 1.00) and 1.04 (95% CI: 0.97, 1.12) per cup per day, respectively. A meta-analysis also produced no significant findings overall, though the cohort studies showed a significant inverse association for tea...
  64. pmc Dairy consumption and ovarian cancer risk in the Netherlands Cohort Study on Diet and Cancer
    M Mommers
    Department of Epidemiology, NUTRIM, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands
    Br J Cancer 94:165-70. 2006
    ..00-2.36; P(trend)=0.11), respectively. Lactose or dairy fat intakes were not associated with serous ovarian cancer risk. Our results do not support an association between consumption of dairy products or lactose intake and ovarian cancer...
  65. doi request reprint Alcohol consumption, cigarette smoking and risk of subtypes of oesophageal and gastric cancer: a prospective cohort study
    J Steevens
    GROW School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Gut 59:39-48. 2010
    ..However, because this was based on retrospective studies, these hypotheses were examined in a prospective cohort...
  66. ncbi request reprint Risk factors, genetic predisposition and mutations in the VHL gene in sporadic renal cell carcinoma: The Netherlands Cohort Study
    B A C Van Dijk
    Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    IARC Sci Publ 156:509-10. 2002
  67. pmc Cigarette smoking, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma
    B A C Van Dijk
    Department of Epidemiology, NUTRIM, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands
    Br J Cancer 95:374-7. 2006
    ..3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations...
  68. pmc Quality of cancer registry data: a comparison of data provided by clinicians with those of registration personnel
    L J Schouten
    Department of Cancer Registration and Epidemiology, Comprehensive Cancer Centre Limburg IKL, Maastricht, The Netherlands
    Br J Cancer 68:974-7. 1993
    ..This study has shown that registration personnel are able to collect data with a high degree of accuracy...
  69. ncbi request reprint Toenails: an easily accessible and long-term stable source of DNA for genetic analyses in large-scale epidemiological studies
    Simone G van Breda
    Clin Chem 53:1168-70. 2007
  70. ncbi request reprint Alcohol intake and renal cell cancer in a pooled analysis of 12 prospective studies
    Jung Eun Lee
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 99:801-10. 2007
    ..An inverse association between alcohol intake and risk of renal cell cancer has been suggested in a few prospective studies, but each of these studies included a small number of cases...
  71. doi request reprint Long-term exposure to traffic-related air pollution and lung cancer risk
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Epidemiology 19:702-10. 2008
    ..Most studies on the association between lung cancer and air pollution have investigated mortality. There have been few studies of lung cancer incidence...
  72. ncbi request reprint Primary central nervous system lymphomas: incidence and survival in the Southern and Eastern Netherlands
    Gitty A C van der Sanden
    Eindhoven Cancer Registry, Comprehensive Cancer Centre South IKZ, Eindhoven, The Netherlands
    Cancer 94:1548-56. 2002
    ..In the current study, the authors describe the incidence, treatment, and survival of an unselected group of patients with PCNSL in the southern and eastern Netherlands...
  73. ncbi request reprint Dairy products and ovarian cancer: a pooled analysis of 12 cohort studies
    Jeanine M Genkinger
    Department of Nutrition, Harvard School of Public Health, Room 339, Building 2, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:364-72. 2006
    ..Although case-control studies have reported conflicting results for dairy foods and lactose, several cohort studies have shown positive associations between skim milk, lactose, and ovarian cancer...
  74. ncbi request reprint A pooled analysis of 12 cohort studies of dietary fat, cholesterol and egg intake and ovarian cancer
    Jeanine M Genkinger
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Cancer Causes Control 17:273-85. 2006
    ..Results for histologic subtypes were similar. Overall, fat, cholesterol and egg intakes were not associated with ovarian cancer risk. The positive association for saturated fat intake at very high intakes merits further investigation...
  75. ncbi request reprint Intake of the major carotenoids and the risk of epithelial ovarian cancer in a pooled analysis of 10 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 119:2148-54. 2006
    ..These results suggest that consumption of the major carotenoids during adulthood does not play a major role in the incidence of ovarian cancer...
  76. pmc Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study)
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 116:196-202. 2008
    ..Several studies have found an effect on mortality of between-city contrasts in long-term exposure to air pollution. The effect of within-city contrasts is still poorly understood...
  77. ncbi request reprint Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies
    Jung Eun Lee
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Int J Cancer 121:2246-53. 2007
    ..Instead, greater consumption of coffee and tea may be associated with a lower risk of renal cell cancer. (c) 2007 Wiley-Liss, Inc...
  78. doi request reprint A compendium of familial relative risks of cancer among first degree relatives: a population-based study
    Maurice P Zeegers
    Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, School of Medicine, The University of Birmingham, Public Health Building, Edgbaston, Birmingham, United Kingdom
    Int J Cancer 123:1664-73. 2008
    ..Familial clustering of cancer occurs at most sites but is generally modest. Some observed discordant familial clustering is surprising but should be interpreted with caution as their prior probability is low...