R S Reneman

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint Neural activity of the cardiac baroreflex decreases with age in normotensive and hypertensive subjects
    Lilian Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands
    J Hypertens 23:815-23. 2005
  2. ncbi request reprint Non-invasive ultrasound in arterial wall dynamics in humans: what have we learned and what remains to be solved
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Eur Heart J 26:960-6. 2005
  3. ncbi request reprint Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, The Netherlands
    J Vasc Res 43:251-69. 2006
  4. pmc Wall shear stress as measured in vivo: consequences for the design of the arterial system
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, POB 616, 6200 MD Maastricht, The Netherlands
    Med Biol Eng Comput 46:499-507. 2008
  5. ncbi request reprint Effects of assessment and processing techniques on the shape of arterial pressure-distension loops
    A P Hoeks
    Department of Biophysics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    J Vasc Res 37:494-500. 2000
  6. ncbi request reprint An integrated system for the non-invasive assessment of vessel wall and hemodynamic properties of large arteries by means of ultrasound
    P J Brands
    Department of Biophysics, Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD, Maastricht, The Netherlands
    Eur J Ultrasound 9:257-66. 1999
  7. ncbi request reprint In the femoral artery bifurcation, differences in mean wall shear stress within subjects are associated with different intima-media thicknesses
    L Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 19:2933-9. 1999
  8. ncbi request reprint Technical aspects of compliance assessment
    A P Hoeks
    Department of Biophysics, University of Limburg, Maastricht, The Netherlands
    Arch Mal Coeur Vaiss 84:77-81. 1991
  9. ncbi request reprint Mean wall shear stress in the femoral arterial bifurcation is low and independent of age at rest
    L Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Vasc Res 37:112-22. 2000
  10. ncbi request reprint Local application of adenosine induces an increase of capillary diameter in skeletal muscle of anesthetized rabbits
    J Bosman
    Department of Biophysics, Cardiovascular Research Institute Maastricht, University of Limburg, The Netherlands
    J Vasc Res 33:111-8. 1996

Collaborators

  • L Kornet
  • P J Brands
  • T Arts
  • F W Prinzen
  • T Delhaas
  • A M Muijtjens
  • L H Snoeckx
  • R N Cornelussen
  • Koen D Reesink
  • J W M Heemskerk
  • Mirjam G A oude Egbrink
  • Berend E Westerhof
  • M L Bots
  • Roland G Asmar
  • James B Bassingthwaighte
  • J M Meinders
  • P W de Leeuw
  • Arnold P G Hoeks
  • Francesco U S Mattace-Raso
  • Miriam A van Gestel
  • Evelien Hermeling
  • Dick W Slaaf
  • Albert Hofman
  • Jacqueline C M Witteman
  • Geofrey De Visscher
  • Tischa J M van der Cammen
  • Nicole M van Popele
  • A P Hoeks
  • Martijn A W Broeders
  • Marc J van Houwelingen
  • M Van Bilsen
  • G J Van der Vusse
  • Maarten A D H Schalekamp
  • Mirjam G Oude Egbrink
  • Viviane V Th Heijnen
  • Geert Jan Tangelder
  • Maaike Peschar
  • Willem Flameng
  • Marcel Borgers
  • Koen van Rossem
  • Matthijs F M Van Oosterhout
  • L J De Windt
  • M F van Oosterhout
  • M A Broeders
  • J M Willigers
  • M Christianne Hoeberigs
  • Mirjam G A Oude Egbrink
  • Anton H van den Meiracker
  • D W Slaaf
  • Marion A H Feijge
  • Sietze Reitsma
  • Margareta Elg
  • Paul J Barenbrug
  • Willem Jan Bos
  • G J Tangelder
  • Marc A M J van Zandvoort
  • Suzette Elias-Smale
  • Theo Lindhout
  • A Elizabeth Hak
  • Deirdre A M van der Kuip
  • Monique M B Breteler
  • Michiel L Bos
  • Diederick E Grobbee
  • Annette P M van den Elzen
  • Koen J Michels
  • Hans de Swart
  • Veerle Leunens
  • Viviane V T Heijnen
  • Stewart O Sage
  • Jos Van Reempts
  • J Bosman
  • M G Egbrink
  • J Willems
  • T H Roemen
  • W A Coumans

Detail Information

Publications39

  1. ncbi request reprint Neural activity of the cardiac baroreflex decreases with age in normotensive and hypertensive subjects
    Lilian Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands
    J Hypertens 23:815-23. 2005
    ..The decrease in cardiac baroreflex sensitivity (BRS) is often ascribed to decreased distension of the pressure-sensing arterial wall segments. However, alterations in the sensing and processing of neural signals may be involved as well...
  2. ncbi request reprint Non-invasive ultrasound in arterial wall dynamics in humans: what have we learned and what remains to be solved
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Eur Heart J 26:960-6. 2005
    ..The problems encountered in these assessments and the possible solutions to these problems are addressed as well...
  3. ncbi request reprint Wall shear stress--an important determinant of endothelial cell function and structure--in the arterial system in vivo. Discrepancies with theory
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, Maastricht, The Netherlands
    J Vasc Res 43:251-69. 2006
    ..Applications of wall shear stress as in flow-mediated arterial dilation, clinically in use to assess endothelial cell (dys)function, are also addressed. This review starts with some background considerations and some theoretical aspects...
  4. pmc Wall shear stress as measured in vivo: consequences for the design of the arterial system
    Robert S Reneman
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, POB 616, 6200 MD Maastricht, The Netherlands
    Med Biol Eng Comput 46:499-507. 2008
    ..The cells have to be studied under the shear stress conditions they are exposed to in real life...
  5. ncbi request reprint Effects of assessment and processing techniques on the shape of arterial pressure-distension loops
    A P Hoeks
    Department of Biophysics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    J Vasc Res 37:494-500. 2000
    ..It is important to consider these artifacts in interpreting pressure-distension loops in the clinical situation...
  6. ncbi request reprint An integrated system for the non-invasive assessment of vessel wall and hemodynamic properties of large arteries by means of ultrasound
    P J Brands
    Department of Biophysics, Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD, Maastricht, The Netherlands
    Eur J Ultrasound 9:257-66. 1999
    ....
  7. ncbi request reprint In the femoral artery bifurcation, differences in mean wall shear stress within subjects are associated with different intima-media thicknesses
    L Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 19:2933-9. 1999
    ..In both the FC and FS, mean, peak systolic, and maximum cyclic change in shear stress near the posterior wall did not change significantly with age, whereas IMT did increase significantly with age...
  8. ncbi request reprint Technical aspects of compliance assessment
    A P Hoeks
    Department of Biophysics, University of Limburg, Maastricht, The Netherlands
    Arch Mal Coeur Vaiss 84:77-81. 1991
    ..A new method is described to obtain reliable estimates for the arterial diameter and the change in diameter as function of time...
  9. ncbi request reprint Mean wall shear stress in the femoral arterial bifurcation is low and independent of age at rest
    L Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Vasc Res 37:112-22. 2000
    ..Mean wall shear stress is lower in the common than in the superficial femoral artery due to additional reflections from the deep femoral artery...
  10. ncbi request reprint Local application of adenosine induces an increase of capillary diameter in skeletal muscle of anesthetized rabbits
    J Bosman
    Department of Biophysics, Cardiovascular Research Institute Maastricht, University of Limburg, The Netherlands
    J Vasc Res 33:111-8. 1996
    ..It is proposed that the prolonged increase in transmural capillary pressure due to ADO may induce changes in capillary wall configuration, leading to larger diameters...
  11. ncbi request reprint Estimates of regional work in the canine left ventricle
    T Delhaas
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands
    Prog Biophys Mol Biol 69:273-87. 1998
    ..During coronary artery occlusion, however, these values were less reliable, which might be due to inaqdequate knowledge of the (passive) material properties of the myocardium...
  12. ncbi request reprint Differences in near-wall shear rate in the carotid artery within subjects are associated with different intima-media thicknesses
    L Kornet
    Departments of Physiology and Biophysics Cardiovascular Research Institute Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 18:1877-84. 1998
    ..The relative difference between both locations within subjects is independent of age...
  13. ncbi request reprint Heat shock proteins and cardiovascular pathophysiology
    L H Snoeckx
    Department of Physiology, Faculty of Medicine, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Physiol Rev 81:1461-97. 2001
    ..In this review we describe the physiological role of heat shock proteins and discuss their protective potential against various stress agents in the cardiovascular system...
  14. ncbi request reprint Accumulation of arachidonic acid in ischemic/reperfused cardiac tissue: possible causes and consequences
    G J Van der Vusse
    Department of Physiology, Maastricht University, Cardiovascular Research Institute Maastricht, The Netherlands
    Prostaglandins Leukot Essent Fatty Acids 57:85-93. 1997
    ..e., eicosanoids. Arachidonic acid may directly influence ion channel activity, substrate metabolism and signal transduction, thereby affecting the functional characteristics of the ischemic/reperfused myocardium...
  15. ncbi request reprint Ischemic-reperfused isolated working mouse hearts: membrane damage and type IIA phospholipase A2
    L J De Windt
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 280:H2572-80. 2001
    ..These findings argue against a prominent role of type IIA sPLA2 in the development of irreversible cell damage in the ischemic-reperfused murine myocardium...
  16. ncbi request reprint Non-invasive measurement of mechanical properties of arteries in health and disease
    A P Hoeks
    Department of Biophysics, Cardiovascular Research Institute, Maastricht, The Netherlands
    Proc Inst Mech Eng H 213:195-202. 1999
    ..The present paper discusses the techniques in more detail...
  17. ncbi request reprint Endogenous nitric oxide and prostaglandins synergistically counteract thromboembolism in arterioles but not in venules
    M A Broeders
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 21:163-9. 2001
    ....
  18. ncbi request reprint Remodeling by ventricular pacing in hypertrophying dog hearts
    M F van Oosterhout
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University and University Hospital, P.O. Box 616, 6200 MD, Maastricht, The Netherlands
    Cardiovasc Res 49:771-8. 2001
    ..The latter suggests that the local growth response is reduced in hypertrophying hearts...
  19. ncbi request reprint Transcriptional regulation of metabolic processes: implications for cardiac metabolism
    M Van Bilsen
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Pflugers Arch 437:2-14. 1998
    ....
  20. ncbi request reprint Regulation of microvascular thromboembolism in vivo
    Mirjam G Oude Egbrink
    Department of Physiology, Maastricht University, The Netherlands
    Microcirculation 12:287-300. 2005
    ..In addition, the involvement of shear forces in microvascular thromboembolic processes in vivo will be described..
  21. ncbi request reprint Impaired fasting glucose is associated with increased arterial stiffness in elderly people without diabetes mellitus: the Rotterdam Study
    Nicole M van Popele
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Am Geriatr Soc 54:397-404. 2006
    ..To study the association between impaired fasting glucose (IFG) and arterial stiffness in older adults...
  22. ncbi request reprint The onset of ventricular isovolumic contraction as reflected in the carotid artery distension waveform
    Marc J van Houwelingen
    Department of Biophysics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Ultrasound Med Biol 33:371-8. 2007
    ..This study shows that the duration of the isovolumic contraction can be reliably extracted from the carotid artery distension waveform...
  23. ncbi request reprint Carotid artery pulse wave time characteristics to quantify ventriculoarterial responses to orthostatic challenge
    Koen D Reesink
    Department of Biophysics, CARIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    J Appl Physiol 102:2128-34. 2007
    ..We conclude that CA ultrasound and pulse wave analysis enable noninvasive quantification of ventriculoarterial responses to changes in posture...
  24. ncbi request reprint Measurement of local pulse wave velocity: effects of signal processing on precision
    Evelien Hermeling
    Department of Biophysics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Ultrasound Med Biol 33:774-81. 2007
    ..Both methods are less sensitive to (phase) noise than the maximum of the second derivative method and exhibit good precision with a CV of less than 1%...
  25. ncbi request reprint Arterial stiffness, cardiovagal baroreflex sensitivity and postural blood pressure changes in older adults: the Rotterdam Study
    Francesco U S Mattace-Raso
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    J Hypertens 25:1421-6. 2007
    ..In the present study the associations between arterial stiffness and cardiovagal baroreflex sensitivity (BRS) and between BRS and postural blood pressure (BP) changes were investigated within the framework of the Rotterdam Study...
  26. doi request reprint Modeled decomposition of aortic pressure waveforms does not provide estimates for pulse wave velocity
    Evelien Hermeling
    Hypertension 51:e60; author reply e61. 2008
  27. doi request reprint Local blood pressure rather than shear stress should be blamed for plaque rupture
    Arnold P G Hoeks
    J Am Coll Cardiol 52:1107-8; author reply 1108-9. 2008
  28. ncbi request reprint Especially polymorphonuclear leukocytes, but also monomorphonuclear leukocytes, roll spontaneously in venules of intact rat skin: involvement of E-selectin
    Mirjam G A oude Egbrink
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands
    J Invest Dermatol 118:323-6. 2002
    ..One of the adhesion molecules involved in this phenomenon is E-selectin...
  29. ncbi request reprint Hypercholesterolemia enhances thromboembolism in arterioles but not venules: complete reversal by L-arginine
    Martijn A W Broeders
    Department of Physiology, CARIM, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 22:680-5. 2002
    ....
  30. ncbi request reprint Real-time detection of activation patterns in individual platelets during thromboembolism in vivo: differences between thrombus growth and embolus formation
    Miriam A van Gestel
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, NL 6200 MD Maastricht, The Netherlands
    J Vasc Res 39:534-43. 2002
    ..These results show, for the first time, the relation between single platelet activation patterns, which are different during thrombus growth and embolus formation, and their behavior in a thromboembolic process in vivo...
  31. ncbi request reprint Relation between local myocardial growth and blood flow during chronic ventricular pacing
    Matthijs F M Van Oosterhout
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cardiovasc Res 53:831-40. 2002
    ..71). In PACE animals, however, this correlation was poor (r=0.33), because rMBF increased in regions close to the pacing site with initial rMBF<1 and rMBF decreased in regions remote from the pacing site with initial rMBF>1...
  32. ncbi request reprint Both ADP and thrombin regulate arteriolar thrombus stabilization and embolization, but are not involved in initial hemostasis as induced by micropuncture
    Miriam A van Gestel
    Department of Physiology, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    Microcirculation 14:193-205. 2007
    ..Up to now, the relative importance of mediators involved is only partly known. It was the aim of this study to investigate the involvement of ADP and thrombin in subsequent phases of arteriolar hemostasis and thromboembolism in vivo...
  33. ncbi request reprint Carotid diameter variations as a non-invasive tool to examine cardiac baroreceptor sensitivity
    Lilian Kornet
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands
    J Hypertens 20:1165-73. 2002
    ..Moreover, we investigate whether the reduced baroreflex sensitivity in the elderly persists after eliminating the influence of the stiffness of the vessel wall and can be attributed to an impairment of the neural baroreflex pathways...
  34. ncbi request reprint Nirs mediated CBF assessment: validating the indocyanine green bolus transit detection by comparison with coloured microsphere flowmetry
    Geofrey De Visscher
    Department of Molecular Cell Biology, CARIM, University of Maastricht, The Netherlands
    Adv Exp Med Biol 540:37-45. 2003
  35. ncbi request reprint In vivo blockade of platelet ADP receptor P2Y12 reduces embolus and thrombus formation but not thrombus stability
    Miriam A van Gestel
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Arterioscler Thromb Vasc Biol 23:518-23. 2003
    ..ADP is a key platelet agonist in thromboembolism. One of the receptors involved in ADP-induced platelet activation is the P2Y12 receptor, which is a target for antithrombotic drugs...
  36. ncbi request reprint Left ventricular septal and apex pacing for optimal pump function in canine hearts
    Maaike Peschar
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Am Coll Cardiol 41:1218-26. 2003
    ..The goal of this study was to test the hypothesis that left ventricular (LV) pump function is optimal when pacing is performed at the LV near the sites where the impulses exit the Purkinje system...
  37. ncbi request reprint Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study
    Francesco U S Mattace-Raso
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Circulation 113:657-63. 2006
    ..We evaluated whether arterial stiffness is a predictor of coronary heart disease and stroke in a population-based study among apparently healthy subjects...
  38. ncbi request reprint Moderate alcohol consumption is associated with reduced arterial stiffness in older adults: the Rotterdam study
    Francesco U S Mattace-Raso
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    J Gerontol A Biol Sci Med Sci 60:1479-83. 2005
    ..Light-to-moderate alcohol consumption has been associated with a lower risk of cardiovascular disease. The protective effect of alcohol could involve arterial properties as arterial stiffness and distensibility...
  39. ncbi request reprint Cerebral blood flow assessment with indocyanine green bolus transit detection by near-infrared spectroscopy in the rat
    Geofrey De Visscher
    Department of Physiology, CARIM, University of Maastricht, Maastricht, The Netherlands
    Comp Biochem Physiol A Mol Integr Physiol 132:87-95. 2002
    ....